메뉴 건너뛰기




Volumn 25, Issue 2, 2004, Pages 137-145

Two components of delayed rectifier K+ current in heart: Molecular basis, functional diversity, and contribution to repolarization

Author keywords

Action potentials; Anti arrhythmia agents; Beta adrenergic receptors; Long QT syndrome; Potassium channels

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; MEMBRANE PROTEIN; MIRP1 PROTEIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNQ1; UNCLASSIFIED DRUG;

EID: 0442278007     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (62)

References (62)
  • 1
    • 0025351245 scopus 로고
    • + current: Differential sensitivity to block by class III antiarrhythmic agents
    • + current: differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol 1990; 96: 195-215.
    • (1990) J Gen Physiol , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 3
    • 0032999081 scopus 로고    scopus 로고
    • + current: A potential mechanism of the proarrhythmic effects of methanesulfonanilide class III agents
    • + current: a potential mechanism of the proarrhythmic effects of methanesulfonanilide class III agents. Cardiovasc Res 1999; 43: 135-47.
    • (1999) Cardiovasc Res , vol.43 , pp. 135-147
    • Cheng, J.1    Kamiya, K.2    Liu, W.3    Tsuji, Y.4    Toyama, J.5    Kodama, I.6
  • 5
    • 0035110307 scopus 로고    scopus 로고
    • The slow component of the delayed rectifier potassium current in undiseased human ventricular myocytes
    • Virag L, Iost N, Opincariu M, Szolnoky J, Szecsi J, Bogats G, et al. The slow component of the delayed rectifier potassium current in undiseased human ventricular myocytes. Cardiovasc Res 2001; 49: 790-7.
    • (2001) Cardiovasc Res , vol.49 , pp. 790-797
    • Virag, L.1    Iost, N.2    Opincariu, M.3    Szolnoky, J.4    Szecsi, J.5    Bogats, G.6
  • 6
    • 0032402399 scopus 로고    scopus 로고
    • Delayed rectifier potassium current in undiseased human ventricular myocytes
    • Iost N, Virag L, Opincariu M, Szecsi J, Varro A, Papp JG. Delayed rectifier potassium current in undiseased human ventricular myocytes. Cardiovasc Res 1998; 40: 508-15.
    • (1998) Cardiovasc Res , vol.40 , pp. 508-515
    • Iost, N.1    Virag, L.2    Opincariu, M.3    Szecsi, J.4    Varro, A.5    Papp, J.G.6
  • 7
    • 0035916884 scopus 로고    scopus 로고
    • Left ventricular hypertrophy decreases slowly but not rapidly activating delayed rectifier potassium currents of epicardial and endocardial myocytes in rabbits
    • Xu X, Rials SJ, Wu Y, Salata JJ, Liu T, Bharucha DB, et al. Left ventricular hypertrophy decreases slowly but not rapidly activating delayed rectifier potassium currents of epicardial and endocardial myocytes in rabbits. Circulation 2001; 103: 1585-90.
    • (2001) Circulation , vol.103 , pp. 1585-1590
    • Xu, X.1    Rials, S.J.2    Wu, Y.3    Salata, J.J.4    Liu, T.5    Bharucha, D.B.6
  • 9
    • 0035928757 scopus 로고    scopus 로고
    • Ks blockade at high heart rate in guinea pig and rabbit: Implications for arrhythmogenesis in humans
    • Ks blockade at high heart rate in guinea pig and rabbit: implications for arrhythmogenesis in humans. Circulation 2001; 104: 951-6.
    • (2001) Circulation , vol.104 , pp. 951-956
    • Lu, Z.1    Kamiya, K.2    Opthof, T.3    Yasui, K.4    Kodama, I.5
  • 10
    • 0030056967 scopus 로고    scopus 로고
    • Ks play a role in the reverse rate dependence of class III agents?
    • Ks play a role in the reverse rate dependence of class III agents? Circ Res 1996; 78: 26-37.
    • (1996) Circ Res , vol.78 , pp. 26-37
    • Gintant, G.A.1
  • 11
    • 0026542247 scopus 로고
    • Potassium rectifier currents differ in myocytes of endocardial and epicardial origin
    • Furukawa T, Kimura S, Furukawa N, Bassett AL, Myerburg RJ. Potassium rectifier currents differ in myocytes of endocardial and epicardial origin. Circ Res 1992; 70: 91-103.
    • (1992) Circ Res , vol.70 , pp. 91-103
    • Furukawa, T.1    Kimura, S.2    Furukawa, N.3    Bassett, A.L.4    Myerburg, R.J.5
  • 12
    • 0028881535 scopus 로고
    • Ks contributes to the longer action potential of the M cell
    • Ks contributes to the longer action potential of the M cell. Circ Res 1995; 76: 351-65.
    • (1995) Circ Res , vol.76 , pp. 351-365
    • Liu, D.W.1    Antzelevitch, C.2
  • 13
    • 0032211575 scopus 로고    scopus 로고
    • Ks) contribute to the differences in action potential duration in basal left ventricular myocytes in guinea-pig
    • Ks) contribute to the differences in action potential duration in basal left ventricular myocytes in guinea-pig. Cardiovasc Res 1998; 40: 322-31.
    • (1998) Cardiovasc Res , vol.40 , pp. 322-331
    • Bryant, S.M.1    Wan, X.2    Shipsey, S.J.3    Hart, G.4
  • 14
    • 0029844535 scopus 로고    scopus 로고
    • Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium: In vitro and in vivo correlations
    • Anyukhovsky EP, Sosunov EA, Rosen MR. Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium: in vitro and in vivo correlations. Circulation 1996; 94: 1981-8.
    • (1996) Circulation , vol.94 , pp. 1981-1988
    • Anyukhovsky, E.P.1    Sosunov, E.A.2    Rosen, M.R.3
  • 17
    • 0029799072 scopus 로고    scopus 로고
    • Effects of long-term oral administration of amiodarone on the ventricular repolarization of rabbit hearts
    • Iwata H, Kodama I, Suzuki R, Kamiya K, Toyama J. Effects of long-term oral administration of amiodarone on the ventricular repolarization of rabbit hearts. Jpn Circ J 1996; 60: 662-72.
    • (1996) Jpn Circ J , vol.60 , pp. 662-672
    • Iwata, H.1    Kodama, I.2    Suzuki, R.3    Kamiya, K.4    Toyama, J.5
  • 21
    • 0029007356 scopus 로고
    • HERG, a human inward rectifier in the voltage-gated potassium channel family
    • Trudeau MC, Warmke JW, Ganetzky B, Robertson GA. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science 1995; 269: 92-5.
    • (1995) Science , vol.269 , pp. 92-95
    • Trudeau, M.C.1    Warmke, J.W.2    Ganetzky, B.3    Robertson, G.A.4
  • 24
    • 0034962859 scopus 로고    scopus 로고
    • + currents by an antisense oligodeoxynucleotide against IsK (minK) and over-expression of IsK mutant D77N in neonatal mouse hearts
    • + currents by an antisense oligodeoxynucleotide against IsK (minK) and over-expression of IsK mutant D77N in neonatal mouse hearts. Pflügers Arch 2001; 442: 329-35.
    • (2001) Pflügers Arch , vol.442 , pp. 329-335
    • Ohyama, H.1    Kajita, H.2    Omori, K.3    Takumi, T.4    Hiramoto, N.5    Iwasaka, T.6
  • 25
    • 0036554839 scopus 로고    scopus 로고
    • A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?
    • Weerapura M, Nattel S, Chartier D, Caballero R, Hebert TE. A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link? J Physiol 2002; 540: 15-27.
    • (2002) J Physiol , vol.540 , pp. 15-27
    • Weerapura, M.1    Nattel, S.2    Chartier, D.3    Caballero, R.4    Hebert, T.E.5
  • 28
    • 0032538558 scopus 로고    scopus 로고
    • + channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current
    • + channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current. J Biol Chem 1998; 273: 27231-5.
    • (1998) J Biol Chem , vol.273 , pp. 27231-27235
    • Kupershmidt, S.1    Snyders, D.J.2    Raes, A.3    Roden, D.M.4
  • 29
    • 0029854263 scopus 로고    scopus 로고
    • Coassembly of KvLQT1 and minK (IsK) proteins to form cardiac IKs potassium channel
    • Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, et al. Coassembly of KvLQT1 and minK (IsK) proteins to form cardiac IKs potassium channel. Nature 1996; 384: 81-3.
    • (1996) Nature , vol.384 , pp. 81-83
    • Sanguinetti, M.C.1    Curran, M.E.2    Zou, A.3    Shen, J.4    Spector, P.S.5    Atkinson, D.L.6
  • 33
    • 0029023244 scopus 로고
    • Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: Evidence for presence of M cells
    • Drouin E, Charpentier F, Gauthier C, Laurent K, Le Marec H. Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells. J Am Coll Cardiol 1995; 26: 185-92.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 185-192
    • Drouin, E.1    Charpentier, F.2    Gauthier, C.3    Laurent, K.4    Le Marec, H.5
  • 34
    • 0032970148 scopus 로고    scopus 로고
    • Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia
    • Sanguinetti MC. Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia. Ann N Y Acad Sci 1999; 868: 406-13.
    • (1999) Ann N Y Acad Sci , vol.868 , pp. 406-413
    • Sanguinetti, M.C.1
  • 35
    • 0033514263 scopus 로고    scopus 로고
    • Low penetrance in the long-QT syndrome: Clinical impact
    • Priori SG, Napolitano C, Schwartz PJ. Low penetrance in the long-QT syndrome: clinical impact. Circulation 1999; 99: 529-33.
    • (1999) Circulation , vol.99 , pp. 529-533
    • Priori, S.G.1    Napolitano, C.2    Schwartz, P.J.3
  • 36
    • 0032145675 scopus 로고    scopus 로고
    • Evaluation of QT interval duration and dispersion and proposed clinical criteria in diagnosis of long QT syndrome in patients with a genetically uniform type of LQT1
    • Swan H, Saarinen K, Kontula K, Toivonen L, Viitasalo M. Evaluation of QT interval duration and dispersion and proposed clinical criteria in diagnosis of long QT syndrome in patients with a genetically uniform type of LQT1. J Am Coll Cardiol 1998; 32: 486-91.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 486-491
    • Swan, H.1    Saarinen, K.2    Kontula, K.3    Toivonen, L.4    Viitasalo, M.5
  • 37
    • 0025963987 scopus 로고
    • Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action
    • Sanguinetti MC, Jurkiewicz NK, Scott A, Siegl PK. Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action. Circ Res 1991; 68: 77-84.
    • (1991) Circ Res , vol.68 , pp. 77-84
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2    Scott, A.3    Siegl, P.K.4
  • 38
    • 0034966964 scopus 로고    scopus 로고
    • Slow delayed rectifier current and repolarization in canine cardiac Purkinje cells
    • Han W, Wang Z, Nattel S. Slow delayed rectifier current and repolarization in canine cardiac Purkinje cells. Am J Physiol Heart Circ Physiol 2001; 280: H1075-80.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Han, W.1    Wang, Z.2    Nattel, S.3
  • 40
    • 0037127028 scopus 로고    scopus 로고
    • Requirement of a macromolecular signaling complex for β-adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel
    • Marx SO, Kurokawa J, Reiken S, Motoike H, D'Armiento J, Marks AR, et al. Requirement of a macromolecular signaling complex for β-adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 2002; 295: 496-9.
    • (2002) Science , vol.295 , pp. 496-499
    • Marx, S.O.1    Kurokawa, J.2    Reiken, S.3    Motoike, H.4    D'Armiento, J.5    Marks, A.R.6
  • 41
    • 0028292927 scopus 로고
    • A family of potassium channel genes related to eag in drosophila and mammals
    • Warmke JW, Ganetzky B. A family of potassium channel genes related to eag in drosophila and mammals. Proc Natl Acad Sci USA 1994; 91: 3438-42.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3438-3442
    • Warmke, J.W.1    Ganetzky, B.2
  • 44
    • 0032860309 scopus 로고    scopus 로고
    • Ks) components of the delayed rectifier potassium current is associated with additional drug effects on lengthening of cardiac repolarization
    • Ks) components of the delayed rectifier potassium current is associated with additional drug effects on lengthening of cardiac repolarization. J Cardiovasc Pharmacol Ther 1999; 4: 143-150.
    • (1999) J Cardiovasc Pharmacol Ther , vol.4 , pp. 143-150
    • Geelen, P.1    Drolet, B.2    Lessard, E.3    Gilbert, P.4    O'Hara, G.E.5    Turgeon, J.6
  • 45
    • 0029822088 scopus 로고    scopus 로고
    • Ionic mechanisms for prolongation of refractoriness and their proarrhythmic and antiarrhythmic correlates
    • Roden DM. Ionic mechanisms for prolongation of refractoriness and their proarrhythmic and antiarrhythmic correlates. Am J Cardiol 1996; 72: 12-6.
    • (1996) Am J Cardiol , vol.72 , pp. 12-16
    • Roden, D.M.1
  • 46
    • 0030905460 scopus 로고    scopus 로고
    • Emerging class III antiarrhythmic agents: Mechanism of action and proarrhythmic potential
    • Nair LA, Grant AO. Emerging class III antiarrhythmic agents: mechanism of action and proarrhythmic potential. Cardiovasc Drugs Ther 1997; 11: 149-67.
    • (1997) Cardiovasc Drugs Ther , vol.11 , pp. 149-167
    • Nair, L.A.1    Grant, A.O.2
  • 47
    • 0031468470 scopus 로고    scopus 로고
    • Differential effect of beta-adrenergic stimulation on the frequency-dependent electrophysiologic actions of the new class III antiarrhythmics dofetilide, ambasilide, and chromanol 293B
    • Schreieck J, Wang Y, Gjini V, Korth M, Zrenner B, Schomig A, et al. Differential effect of beta-adrenergic stimulation on the frequency-dependent electrophysiologic actions of the new class III antiarrhythmics dofetilide, ambasilide, and chromanol 293B. J Cardiovasc Electrophysiol 1997; 8: 1420-30.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , pp. 1420-1430
    • Schreieck, J.1    Wang, Y.2    Gjini, V.3    Korth, M.4    Zrenner, B.5    Schomig, A.6
  • 48
    • 0033996414 scopus 로고    scopus 로고
    • Ks does not induce early afterdepolarization activity but promotes β-adrenergic agonist-induced delayed afterdepolarization activity
    • Ks does not induce early afterdepolarization activity but promotes β-adrenergic agonist-induced delayed afterdepolarization activity. J Cardiovasc Electrophysiol 2000; 11: 458-65.
    • (2000) J Cardiovasc Electrophysiol , vol.11 , pp. 458-465
    • Burashnikov, A.1    Antzelevitch, C.2
  • 51
    • 0033771820 scopus 로고    scopus 로고
    • + currents have reduced amplitudes and altered kinetics in myocytes from infarcted canine ventricle
    • + currents have reduced amplitudes and altered kinetics in myocytes from infarcted canine ventricle. Cardiovasc Res 2000; 48: 34-43.
    • (2000) Cardiovasc Res , vol.48 , pp. 34-43
    • Jiang, M.1    Cabo, C.2    Yao, J.3    Boyden, P.A.4    Tseng, G.5
  • 52
    • 0033770327 scopus 로고    scopus 로고
    • Pacing-induced heart failure causes a reduction of delayed rectifier potassium currents along with decreases in calcium and transient outward currents in rabbit ventricle
    • Tsuji Y, Opthof T, Kamiya K, Yasui K, Liu W, Lu Z, et al. Pacing-induced heart failure causes a reduction of delayed rectifier potassium currents along with decreases in calcium and transient outward currents in rabbit ventricle. Cardiovasc Res 2000; 48: 300-9.
    • (2000) Cardiovasc Res , vol.48 , pp. 300-309
    • Tsuji, Y.1    Opthof, T.2    Kamiya, K.3    Yasui, K.4    Liu, W.5    Lu, Z.6
  • 53
    • 0034612363 scopus 로고    scopus 로고
    • Effects of experimental heart failure on atrial cellular and ionic electrophysiology
    • Li D, Melnyk P, Feng J, Wang Z, Petrecca K, Shrier A, et al. Effects of experimental heart failure on atrial cellular and ionic electrophysiology. Circulation 2000; 101: 2631-8.
    • (2000) Circulation , vol.101 , pp. 2631-2638
    • Li, D.1    Melnyk, P.2    Feng, J.3    Wang, Z.4    Petrecca, K.5    Shrier, A.6
  • 54
    • 0033498478 scopus 로고    scopus 로고
    • Changes in the mRNA levels of delayed rectifier potassium channels in human atrial fibrillation
    • Lai LP, Su MJ, Lin JL, Lin FY, Tsai CH, Chen YS, et al. Changes in the mRNA levels of delayed rectifier potassium channels in human atrial fibrillation. Cardiology 1999; 92: 248-55.
    • (1999) Cardiology , vol.92 , pp. 248-255
    • Lai, L.P.1    Su, M.J.2    Lin, J.L.3    Lin, F.Y.4    Tsai, C.H.5    Chen, Y.S.6
  • 55
    • 0028890324 scopus 로고
    • Reproducible induction of early afterdepolarization and torsades de pointes arrhythmias by d-sotalol and pacing in dogs with chronic atrioventricular block
    • Vos MA, Verduyn SC, Gorgels AP, Lipcsei GC, Wellens HJ. Reproducible induction of early afterdepolarization and torsades de pointes arrhythmias by d-sotalol and pacing in dogs with chronic atrioventricular block. Circulation 1995; 91: 864-72.
    • (1995) Circulation , vol.91 , pp. 864-872
    • Vos, M.A.1    Verduyn, S.C.2    Gorgels, A.P.3    Lipcsei, G.C.4    Wellens, H.J.5
  • 56
    • 0032530525 scopus 로고    scopus 로고
    • Enhanced susceptibility for acquired torsades de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling
    • Vos MA, de Groot SH, Verduyn SC, van der Zande J, Leunissen HD, Cleutjens JP, et al. Enhanced susceptibility for acquired torsades de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling. Circulation 1998; 98: 1125-35.
    • (1998) Circulation , vol.98 , pp. 1125-1135
    • Vos, M.A.1    De Groot, S.H.2    Verduyn, S.C.3    Van Der Zande, J.4    Leunissen, H.D.5    Cleutjens, J.P.6
  • 57
    • 0032530552 scopus 로고    scopus 로고
    • Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic atriventricular block and acquired torsades de pointes
    • Volders PG, Sipido KR, Vos MA, Kulcsar A, Verduyn SC, Wellens HJ. Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic atriventricular block and acquired torsades de pointes. Circulation 1998; 98: 1136-47.
    • (1998) Circulation , vol.98 , pp. 1136-1147
    • Volders, P.G.1    Sipido, K.R.2    Vos, M.A.3    Kulcsar, A.4    Verduyn, S.C.5    Wellens, H.J.6
  • 59
    • 0037044405 scopus 로고    scopus 로고
    • Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block
    • Tsuji Y, Opthof T, Yasui K, Inden Y, Takemura H, Niwa N, et al. Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block. Circulation 2002; 106: 2012-8.
    • (2002) Circulation , vol.106 , pp. 2012-2018
    • Tsuji, Y.1    Opthof, T.2    Yasui, K.3    Inden, Y.4    Takemura, H.5    Niwa, N.6
  • 60
    • 0034917323 scopus 로고    scopus 로고
    • Organizing evidence on QT prolongation and occurrence of torsades de pointes with non-antiarrhythmic drugs: A call for consensus
    • De Ponti F, Poluzzi E, Montanaro N. Organizing evidence on QT prolongation and occurrence of torsades de pointes with non-antiarrhythmic drugs: a call for consensus. Eur J Clin Pharmacol 2001; 57: 185-209.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 185-209
    • De Ponti, F.1    Poluzzi, E.2    Montanaro, N.3
  • 62
    • 0035040834 scopus 로고    scopus 로고
    • Pharmacogenetics and drug-induced arrhythmias
    • Roden DM. Pharmacogenetics and drug-induced arrhythmias. Cardiovasc Res 2001; 50: 224-31.
    • (2001) Cardiovasc Res , vol.50 , pp. 224-231
    • Roden, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.