Concomitant block of the rapid (I(Kr)) and slow (I(Ks)) components of the delayed rectifier potassium current is associated with additional drug effects on lengthening of cardiac repolarization

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 4, Issue 3, 1999, Pages 143-150

  Geelen, P ^a   Drolet, B ^a   Lessard, E ^a   Gilbert, P ^a   O'Hara, G E ^a   Turgeon, J ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

I(Kr) blockers; I(Ks) blockers; Potassium channel blockers; Proarrhythmia

Indexed keywords

ACECAINIDE; DOFETILIDE; INDAPAMIDE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION;

ANIMAL TISSUE; ARTICLE; DISEASE PREDISPOSITION; DRUG EFFECT; DRUG INFUSION; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; GUINEA PIG; HEART ARRHYTHMIA; HEART MUSCLE PERFUSION; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; ISOLATED HEART; MALE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RECEPTOR BLOCKING;

EID: 0032860309     PISSN: 10742484     EISSN: None     Source Type: Journal    
DOI: 10.1177/107424849900400303     Document Type: Article

References (33)