Regional localization of ERG, the channel protein responsible for the rapid component of the delayed rectifier, K+ current in the ferret heart

Circulation Research

Volumn 81, Issue 1, 1997, Pages 128-135

  Brahmajothi, Mulugu V ^a   Morales, Michael J ^a,b   Reimer, Keith A ^a   Strauss, Harold C ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Atrium; Immunolocalization; In situ hybridization; K+ channel; Ventricle

Indexed keywords

MEMBRANE PROTEIN; POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FERRET; FLUORESCENCE IN SITU HYBRIDIZATION; HEART ARRHYTHMIA; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; IMMUNOFLUORESCENCE; LONG QT SYNDROME; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

EID: 0031007731     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.81.1.128     Document Type: Article

References (47)

1. Barry DM, Nerbonne JM. Myocardial potassium channels: electrophysiological and molecular diversity. In: Annual Review of Physiology. San Diego, Calif: Annual Reviews Inc; 1996;58:363-394.
2. Campbell DL, Rasmusson RL, Comer MB, Strauss HC. The cardiac calcium-independent transient outward potassium current: kinetics, molecular properties, and role in ventricular repolarization. In: Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. 2nd ed. Philadelphia, Pa: WB Saunders Co; 1995:83-96.
3. Kass RS. Delayed potassium channels in the heart: cellular, molecular, and regulatory properties. In: Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. 2nd ed. Philadelphia, Pa: WB Saunders Co; 1995:74-82.
4. Trudeau MC, Warrake JW, Ganetzky B, Robertson GA. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science. 1995;269:92-95.
5. Kr potassium channel. Cell. 1995;81:299-307.
6. Ks cardiac potassium current. Nature. 1996;384:78-80.
7. v, potassium channel. Nature. 1996;384:80-83.
8. Chandy KG, Gutman GA. Voltage-gated potassium channel genes. In: North RA, ed. Handbook of Receptors and Channels: Ligand and Voltage-Gated Ion Channels. Boca Raton, Fla: CRC Press; 1995:1-71.
9. + channels altered by presence of θ-subunit. Nature. 1994;369:289-294.
10. + channel β subunit increases the rate of C-type inactivation from the cytoplasmic side of the channel. Proc Natl Acad Sci U.S.A. 1996;93:15119-15123.
11. vβ1 subunits. J Biol Chem. 1996;271:28311-28317.
12. + channel β subunit to specifically enhance Kv2.2(CDRK) expression. J Biol Chem. 1996;271:26341-26348.
13. + channel surface expression through effects early in biosynthesis. Neuron. 1996;16:843-852.
14. + channels detected in vivo. Nature. 1993; 365:72-75.
15. + channels in terminal and juxtaparanodal regions of neurons. Nature. 1993;365:75-79.
16. + channel mRNA in isolated ferret cardiac myocytes. Circ Res. 1996;78:1083-1089.
17. Dixon JE, McKinnon D. Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats. Circ Res. 1994;75:252-260.
18. + channel in ventricular muscle: a molecular correlate for the transient outward current. Circ Res. 1996;79:659-668.
19. + channels? Circ Res. 1994;77:361-369.
20. Beckh S, Pongs O. Members of the RCK potassium channel family are differentially expressed in the rat nervous system. EMBO J. 1990;9:777-782.
21. + channel isoforms in the developing rat brain. FEBS Lett. 1993;324:205-210.
22. + channel polypeptides in rat hippocampal neurons developing in situ and in vitro. J Neurosci. 1995;15:3840-3851.
23. Warmke JW, Ganetzky B. A family of potassium channel genes related to eag in Drosophila and mammals. Proc Natl Acad Sci U S A. 1994;91:3438-3442.
24. Curran ME, Splawski I, Timothy KW, Vincent GM, Green ED, Keating MT. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell. 1995;80:795-803.
25. + current in cardiac myocyles by dofetilide. J Pharmacol Exp Ther. 1992;262:809-817.
26. + current by amokalant in rabbit ventricular myocytes. Circ Res. 1993;73:857-868.
27. + current by dofetilide. Circ Res. 1993;72:75-83.
28. Colatsky TJ, Argentieri TM. Potassium channel blockers as antiarrhythmic drugs. Drug Dev Res. 1994;33:255-249.
29. Campbell DL, Rasmusson RL, Ou Y, Strauss HC. The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes, I: basic characterization and kinetic analysis. J Gen Physiol. 1993;101:571-601.
30. Pellequer J-L, Westhof E, van Regenmortel MHV. Epitope predictions from the primary structure of proteins. In: Wisdom GB, ed. Peptide Antigens: A Practical Approach. Oxford, UK: IRL Press; 1994:7-25.
31. Tam JP. Immunization with peptide-carrier complexes: traditional and multiple-antigen peptide systems. In: Wisdom GB, ed. Peptide Antigens: A Practical Approach. Oxford, UK: IRL Press; 1994:83-115.
32. Harlow E, Lane D. Antibodies: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Press; 1988.
33. Young JM, Cheadle C, Foulke JS Jr, Drohan WN, Sarver N. Utilization of an Epstein-Barr virus replicon as a eukaryotic expression vector. Gene. 1988;62:171-185.
34. Gorza L, Ausoni S, Merciai N, Hastings KEM, Schiaffino S. Regional differences in troponin I isoform switching during rat heart development. Dev Biol. 1993;156:253-264.
35. Op't Hof T. The Mammalian Sinoatrial Node: A Comparative Morphological and Electrophysiological Study. Amsterdam, Netherlands: University of Amsterdam; 1986:250, Thesis.
36. Giles W, Imaizumi Y. Comparison of potassium currents in rabbit atrial and ventricular cells. J Physiol (Lond). 1988;405:123-145.
37. Litovsky SH, Antzelevitch C. Transient outward current prominent in canine epicardium but not endocardium. Circ Res. 1988;62:116-126.
38. + currents in nonfailing human hearts: similarities between right septal subendocardial and left subepicardial ventricular myocytes. Circulation. 1995;92:1179-1187.
39. Näbauer M, Beuckelmann DJ, Uberfuhr P, Steinbeck G. Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle. Circulation. 1996;93:168-177.
40. Antzelevitch C, Sicouri S, Lukas A, Nesterenko VV, Liu D-W, Di Diego JM. Regional differences in the electrophysiology of ventricular cells: physiological and clinical implications. In: Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. 2nd ed. Philadelphia, Pa: WB Sounders Co; 1995:228-245.
41. Ks contributes to the longer action potential of the M cell. Circ Res. 1995;76:351-365.
42. + current in rabbit atrial myocytes. Am J Physiol. 1995;38:H524-H532.
43. Kr) from single ferret atrial myocytes. Biophys J. 1996;70:2704-2715.
44. + channel, erg. Circ Res. 1997;80:261-268.
45. Veldkamp MW, van Ginneken ACG, Opthof T, Bouman LN. Delayed rectifier channels in human ventricular myocytes. Circulation. 1995;92:3497-3504.
46. + current in human ventricular myocytes. Circ Res. 1996;78:689-696.
47. Schwartz PJ, Locati EH, Napolitano C, Priori SG. The long QT syndrome. In: Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Beside. 2nd ed. Philadelphia, Pa: WB Saunders; 1995:788-811.