Caspase-7 Gene Disruption Reveals an Involvement of the Enzyme during the Early Stages of Apoptosis

Journal of Biological Chemistry

Volumn 279, Issue 2, 2004, Pages 1030-1039

  Korfali, Nadia ^a   Ruchaud, Sandrine ^a   Loegering, David ^b   Bernard, Delphine ^c   Dingwall, Colin ^d   Kaufmann, Scott H ^b   Earnshaw, William C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b MAYO CLINIC   (United States)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; DNA; DRUG PRODUCTS; ENZYMES; GENES;

FRAGMENTATION;

BIOCHEMISTRY;

CASPASE 7; ETOPOSIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLSERINE; STAUROSPORINE;

ALLELE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL TYPE; CELL VIABILITY; CHICKEN; DNA CLEAVAGE; DNA DAMAGE; ENZYME ACTIVATION; ENZYME METABOLISM; GENE DISRUPTION; GENETIC ANALYSIS; INTERNALIZATION; MOLECULAR CLONING; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; TISSUE SPECIFICITY;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANNEXIN A5; APOPTOSIS; BLOTTING, SOUTHERN; CASPASE 7; CASPASES; CELL LINE; CELL NUCLEUS; CELL SURVIVAL; CHICKENS; COLORING AGENTS; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOPOSIDE; HELA CELLS; HUMANS; IMMUNOBLOTTING; IN SITU NICK-END LABELING; KINETICS; LAMIN TYPE B; MODELS, GENETIC; PHOSPHATIDYLSERINES; POLY(ADP-RIBOSE) POLYMERASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAUROSPORINE; TIME FACTORS;

ANIMALIA; GALLUS GALLUS;

EID: 0346463061     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306277200     Document Type: Article

References (63)

1. Ellis, R. E., Yuan, J., and Horvitz, H. R. (1991) Annu. Rev. Cell Biol. 7, 663-698
2. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M., and Horvitz, H. R. (1993) Cell 75, 641-652
3. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 1312-1316
4. Earnshaw, W. C., Martins, L. M., and Kaufmann, S. H. (1999) Annu. Rev. Biochem. 68, 383-424
5. Hengartner, M. O. (2000) Nature 407, 770-776
6. Budihardjo, I., Oliver, H., Lutter, M., Luo, X., and Wang, X. (1999) Annu. Rev. Cell Dev. Biol. 15, 269-290
7. Creagh, E. M., Martin, S. J., Vanags, D. M., Porn-Ares, M. I., Coppola, S., Burgess, D. H., and Orrenius, S. (2001) Biochem. Soc. Trans. 29, 696-702
8. Kuida, K., Haydar, T. F., Kuan, C. Y., Gu, Y., Taya, C., Karasuyama, H., Su, M. S., Rakic, P., Flavell, R. A., Porn-Ares, M. I., Coppola, S., Burgess, D. H., and Orrenius, S. (1998) Cell 94, 325-337
9. Varfolomeev, E. E., Schuchmann, M., Luria, V., Chiannilkulchai, N., Beckmann, J. S., Mett, I. L., Rebrikov, D., Brodianski, V. M., Kemper, O. C., Kollet, O., Lapidot, T., Soffer, D., Sobe, T., Avraham, K. B., Goncharov, T., Holtmann, H., Lonai, P., and Wallach, D. (1998) Immunity 9, 267-276
10. Woo, M., Hakem, R., Soengas, M. S., Duncan, G. S., Shahinian, A., Kägi, D., Hakem, A., McCurrach, M., Khoo, W., Kaufman, S. A., Senaldi, G., Howard, T., Lowe, S. W., and Mak, T. W. (1998) Genes Dev. 12, 806-819
11. Le, D. A., Wu, Y., Huang, Z., Matsushita, K., Plesnila, N., Augustinack, J. C., Hyman, B. T., Yuan, J., Kuida, K., Flavell, R. A., and Moskowitz, M. A. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 15188-15193
12. Bergeron, L., Perez, G. I., Macdonald, G., Shi, L., Sun, Y., Jurisicova, A., Varmuza, S., Latham, K. E., Flaws, J. A., Salter, J. C., Hara, H., Moskowitz, M. A., Li, E., Greenberg, A., Tilly, J. L., and Yuan, J. (1998) Genes Dev. 12, 1304-1314
13. Lassus, P., Opitz-Araya, X., Lazebnik, Y., Chilcote, T. J., Lord, J., Salmon, M., Earnshaw, W. C., and Kaufmann, S. H. (2002) Science 297, 1352-1354
14. Slee, E. A., Adrain, C., and Martin, S. J. (1999) Cell Death Differ. 6, 1067-1074
15. Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. (1995) Cancer Res. 55, 2737-2742
16. Faleiro, L., Kobayashi, R., Fearnhead, H., and Lazebnik, Y. (1997) EMBO J. 16, 2271-2281
17. Martins, L. M., Kottke, T., Mesner, P. W., Basi, G. S., Sinha, S., Frigon, N. J., Tatar, E., Tung, J. S., Bryant, K., Takahashi, A., Svingen, P. A., Madden, B. J., McCormick, D. J., Earnshaw, W. C., and Kaufmann, S. H. (1997) J. Biol. Chem. 272, 7421-7430
18. Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. (1998) Mol. Cell 1, 949-957
19. Samejima, K., Tone, S., and Earnshaw, W. C. (2001) J. Biol. Chem. 276, 45427-45432
20. Kottke, T. J., Blajeski, A. L., Meng, X. W., Svingen, P. A., Ruchaud, S., Mesner, P. W., Jr., Boerner, S. A., Samejima, K., Henriquez, N. V., Chilcote, T. J., Lord, J., Salmon, M., Earnshaw, W. C., and Kaufmann, S. H. (2002) J. Biol. Chem. 277, 804-815
21. Allsopp, T. E., McLuckie, J., Kerr, L. E., Macleod, M., Sharkey, J., and Kelly, J. S. (2000) Cell Death Differ. 7, 984-993
22. Ruchaud, S., Korfali, N., Villa, P., Kottke, T. J., Dingwall, C., Kaufmann, S. H., and Earnshaw, W. C. (2002) EMBO J. 21, 1967-1977
23. Kuida, K., Zheng, T. S., Na, S., Kuan, C., Yang, D., Karasuyama, H., Rakic, P., and Flavell, R. A. (1996) Nature 384, 368-372
24. Jänicke, R. U., Ng, P., Sprengart, M. L., and Porter, A. G. (1998) J. Biol. Chem. 273, 15540-15545
25. Talanian, R. V., Quinlan, C., Trautz, S., Hackett, M. C., Mankovich, J. A., Banach, D., Ghayur, T., Brady, K. D., and Wong, W. W. (1997) J. Biol. Chem. 272, 9677-9682
26. McGee, M. M., Hyland, E., Campiani, G., Ramunno, A., Nacci, V., and Zisterer, D. M. (2002) FEBS Lett. 515, 66-70
27. Germain, M., Affar, E. B., D'Amours, D., Dixit, V. M., Salvesen, G. S., and Poirier, G. G. (1999) J. Biol. Chem. 274, 28379-28384
28. Nitta, T., Igarashi, K., Yamashita, A., Yamamoto, M., and Yamamoto, N. (2001) Exp. Cell Res. 265, 174-183
29. Ruiz-Vela, A., Gonzalez de Buitrago, G., Martinez, A. C., Le, X. F., Marcelli, M., McWatters, A., Nan, B., Mills, G. B., O'Brian, C. A., and Bast, R. C., Jr. (1999) EMBO J. 18, 4988-4998
30. Bras, A., Ruiz-Vela, A., Gonzalez de Buitrago, G., and Martinez, A. C. (1999) FASEB J. 13, 931-944
31. Marsden, V. S., O'Connor, L., O'Reilly, L. A., Silke, J., Metcalf, D., Ekert, P. G., Huang, D. C., Cecconi, F., Kuida, K., Tomaselli, K. J., Roy, S., Nicholson, D. W., Vaux, D. L., Bouillet, P., Adams, J. M., and Strasser, A. (2002) Nature 419, 634-637
32. Zheng, T. S., Hunot, S., Kuida, K., and Flavell, R. A. (1999) Cell Death Differ. 6, 1043-1053
33. Nakagawa, T., Zhu, H., Morishima, N., Li, E., Xu, J., Yankner, B. A., and Yuan, J. (2000) Nature 403, 98-103
34. Zheng, T. S., Hunot, S., Kuida, K., Momoi, T., Srinivasan, A., Nicholson, D. W., Lazebnik, Y., and Flavell, R. A. (2000) Nat. Med. 6, 1241-1247
35. Buerstedde, J.-M., and Takeda, S. (1991) Cell 67, 179-188
36. Wood, E. R., and Earnshaw, W. C. (1990) J. Cell Biol. 111, 2839-2850
37. Kottke, T. J., Blajeski, A. L., Martins, L. M., Mesner, P. W. J., Davidson, N. E., Earnshaw, W. C., Armstrong, D. K., and Kaufmann, S. H. (1999) J. Biol. Chem. 274, 15927-15936
38. Wyllie, A. H., Kerr, J. F. R., and Currie, A. R. (1980) Int. Rev. Cytol. 68, 251-305
39. Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., and Nagata, S. (1998) Nature 391, 43-50
40. Liu, X., Zou, H., Slaughter, C., and Wang, X. (1997) Cell 89, 175-184
41. Halenbeck, R., MacDonald, H., Roulston, A., Chen, T. T., Conroy, L., and Williams, L. T. (1998) Curr. Biol. 8, 537-540
42. Li, L. Y., Luo, X., and Wang, X. (2001) Nature 412, 95-99
43. Parrish, J., Li, L., Klotz, K., Ledwich, D., Wang, X., and Xue, D. (2001) Nature 412, 90-94
44. Zhivotovsky, B., Samali, A., Gahm, A., and Orrenius, S. (1999) Cell Death Differ. 6, 644-651
45. Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. (1993) Cancer Res. 53, 3976-3985
46. Salvesen, G. S., Dixit, V. M., Zheng, T. S., Hunot, S., Kuida, K., Momoi, T., Srinivasan, A., Nicholson, D. W., Lazebnik, Y., and Flavell, R. A. (1997) Cell 91,443-446
47. Lazebnik, Y. A., Cole, S., Cooke, C. A., Nelson, W. G., and Earnshaw, W. C. (1993) J. Cell Biol. 123, 7-22
48. Koopman, G., Reutelingsperger, C. P. M., Kuijten, G. A. M., Keehnen, R. M. J., Pals, S. T., and van Oers, M. H. J. (1994) Blood 84, 1415-1420
49. Martin, S. J., Reutelingsperger, C. P., McGahon, A. J., Rader, J. A., van Schie, R. C., LaFace, D. M., and Green, D. R. (1995) J. Exp. Med. 182, 1545-1556
50. Vanags, D. M., Porn-Ares, M. I., Coppola, S., Burgess, D. H., and Orrenius, S. (1996) J. Biol. Chem. 271, 31075-31085
51. Frasch, S. C., Henson, P. M., Kailey, J. M., Richter, D. A., Janes, M. S., Fadok, V. A., and Bratton, D. L. (2000) J. Biol. Chem. 275, 23065-23073
52. Ferraro-Peyret, C., Quemeneur, L., Flacher, M., Revillard, J. P., and Genestier, L. (2002) J. Immunol. 169, 4805-4810
53. Slee, E. A., Adrain, C., and Martin, S. J. (2001) J. Biol. Chem. 276, 7320-7326
54. Ghayur, T., Hugunin, M., Talanian, R. V., Ratnofsky, S., Quinlan, C., Emoto, Y., Pandey, P., Datta, R., Huang, Y., Kharbanda, S., Allen, H., Kamen, R., Wong, W., and Kufe, D. (1996) J. Exp. Med. 184, 2399-2404
55. McIlroy, D., Sakahira, H., Talanian, R. V., and Nagata, S. (1999) Oncogene 18, 4401-4408
56. Lane, J. D., Vergnolle, M. A., Woodman, P. G., and Allan, V. J. (2001) J. Cell Biol. 153, 1415-1426
57. Bourdon, J. C., Renzing, J., Robertson, P. L., Fernandes, K. N., and Lane, D. P. (2002) J. Cell Biol. 158, 235-246
58. Martin, S. J., Finucane, D. M., Amarante-Mendes, G. P., O'Brien, G. A., and Green, D. R. (1996) J. Biol. Chem. 271, 28753-28756
59. Rodriguez, J., and Lazebnik, Y. (1999) Genes Dev. 13, 3179-3184
60. Riedl, S. J., Fuentes-Prior, P., Renatus, M., Kairies, N., Krapp, S., Huber, R., Salvesen, G. S., and Bode, W. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 14790-14795
61. Coelho, D., Holl, V., Weltin, D., Lacornerie, T., Magnenet, P., Dufour, P., and Bischoff, P. (2000) Br. J. Cancer 83, 642-649
62. Rao, R. V., Hermel, E., Castro-Obregon, S., del Rio, G., Ellerby, L. M., Ellerby, H. M., and Bredesen, D. E. (2001) J. Biol. Chem. 276, 33869-33874
63. Le, X. F., Marcelli, M., McWatters, A., Nan, B., Mills, G. B., O'Brian, C. A., and Bast, R. C., Jr. (2001) Oncogene 20, 8258-8269