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Volumn 14, Issue 9, 2001, Pages 1331-1341

Gene Therapy for Bovine Fatty Liver : Possibilities and Problems - A Review

Author keywords

Bovine; Fatty Liver; Gene Therapy; VLDL

Indexed keywords

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0345859711     PISSN: 10112367     EISSN: None     Source Type: Journal    
DOI: 10.5713/ajas.2001.1331     Document Type: Review
Times cited : (3)

References (85)
  • 1
    • 0029040203 scopus 로고
    • Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation
    • Abdel-Fattah, G., M. L. Fernandez and D. J. McNamara. 1995. Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation. J. Lipid Res. 36:1188-1198.
    • (1995) J. Lipid Res. , vol.36 , pp. 1188-1198
    • Abdel-Fattah, G.1    Fernandez, M.L.2    McNamara, D.J.3
  • 2
    • 0017070905 scopus 로고
    • Subcellular localization of B apolipoprotein of plasma lipoproteins in rat liver
    • Alexander, C. A., R. L. Hamilton and R. J. Havel. 1976. Subcellular localization of B apolipoprotein of plasma lipoproteins in rat liver. J. Cell Biol. 69:241-263.
    • (1976) J. Cell Biol. , vol.69 , pp. 241-263
    • Alexander, C.A.1    Hamilton, R.L.2    Havel, R.J.3
  • 3
    • 0025319210 scopus 로고
    • Possible role of the Golgi apparatus in the assembly of very low density lipoproteins
    • Bamberger, M. J. and M. D. Lane. 1990. Possible role of the Golgi apparatus in the assembly of very low density lipoproteins. Proc. Natl. Acad. Sci. USA. 87:3555-3562.
    • (1990) Proc. Natl. Acad. Sci. USA. , vol.87 , pp. 3555-3562
    • Bamberger, M.J.1    Lane, M.D.2
  • 4
    • 0024429636 scopus 로고
    • Plasma lipoproteins and apolipoproteins in the preruminant calf, Bos spp: Density distribution, physicochemical properties, and the in vivo evaluation of the contribution of the liver to lipoprotein homeostasis
    • Bauchart, D., D. Durand, P. M. Laplaud, P. Forgez, S. Goulinet, and M. J. Chapman. 1989. Plasma lipoproteins and apolipoproteins in the preruminant calf, Bos spp: density distribution, physicochemical properties, and the in vivo evaluation of the contribution of the liver to lipoprotein homeostasis. J. Lipid Res. 30:1499-1514.
    • (1989) J. Lipid Res. , vol.30 , pp. 1499-1514
    • Bauchart, D.1    Durand, D.2    Laplaud, P.M.3    Forgez, P.4    Goulinet, S.5    Chapman, M.J.6
  • 6
    • 0026892035 scopus 로고
    • Effect of prepartum dry matter intake and liver triglyceride concentration and early lactation
    • Bertics, S. J., R. R. Grummer, C. Cadorniga-Valino, D. W. LaCount and E. E. Stoddard. 1992. Effect of prepartum dry matter intake and liver triglyceride concentration and early lactation. J. Dairy Sci. 75:1914.
    • (1992) J. Dairy Sci. , vol.75 , pp. 1914
    • Bertics, S.J.1    Grummer, R.R.2    Cadorniga-Valino, C.3    LaCount, D.W.4    Stoddard, E.E.5
  • 7
    • 0030948670 scopus 로고    scopus 로고
    • Gene therapy: Progress, problems, prospects
    • Blau, H. and P. Khavari. 1997. Gene therapy: progress, problems, prospects. Nat. Med. 3:612-613.
    • (1997) Nat. Med. , vol.3 , pp. 612-613
    • Blau, H.1    Khavari, P.2
  • 10
    • 0023892889 scopus 로고
    • High density lipoproteins from bovine plasma and follicular fluid do not possess a high affinity for glycosaminoglycans
    • Brantmeier, S. A., R. R. Grummer and R. L. Ax. 1988. High density lipoproteins from bovine plasma and follicular fluid do not possess a high affinity for glycosaminoglycans. Lipids 23:
    • (1988) Lipids , vol.23
    • Brantmeier, S.A.1    Grummer, R.R.2    Ax, R.L.3
  • 11
    • 0346111697 scopus 로고    scopus 로고
    • Differences in activity of hepatic microsomal triglyceride transfer protein among species
    • Bremmer, D. R., R. R. Grummer and S. J. Bertics. 1998. Differences in activity of hepatic microsomal triglyceride transfer protein among species. J. Dairy Sci. 81:351.
    • (1998) J. Dairy Sci. , vol.81 , pp. 351
    • Bremmer, D.R.1    Grummer, R.R.2    Bertics, S.J.3
  • 12
    • 0346742239 scopus 로고    scopus 로고
    • Academic Press, San Diego, California
    • Brody, T. 1999. Nutritional Biochemistry (2nd. Ed.), Academic Press, San Diego, California, Carwright, I. J. and J. A. Higgins. 1995. Intracellular events in the assembly of very low density lipoprotein lipids with apolipoprotein B in isolated rabbit hepatocytes. Biochem. J. 310:897-907.
    • (1999) Nutritional Biochemistry (2nd. Ed.)
    • Brody, T.1
  • 13
    • 0029128035 scopus 로고
    • Intracellular events in the assembly of very low density lipoprotein lipids with apolipoprotein B in isolated rabbit hepatocytes
    • Brody, T. 1999. Nutritional Biochemistry (2nd. Ed.), Academic Press, San Diego, California, Carwright, I. J. and J. A. Higgins. 1995. Intracellular events in the assembly of very low density lipoprotein lipids with apolipoprotein B in isolated rabbit hepatocytes. Biochem. J. 310:897-907.
    • (1995) Biochem. J. , vol.310 , pp. 897-907
    • Carwright, I.J.1    Higgins, J.A.2
  • 14
    • 0019162990 scopus 로고
    • Animal lipoproteins: Chemistry, structure, and comparative aspects
    • Chapman, M. J. 1980. Animal lipoproteins: chemistry, structure, and comparative aspects. J. Lipid Res. 789-853.
    • (1980) J. Lipid Res. , pp. 789-853
    • Chapman, M.J.1
  • 15
    • 0025667289 scopus 로고
    • Regulation of apoB secretion from HepG2 cells; evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge
    • Cianflone, K. M., Z. Yasruel, M. A. Rodriguez, D. Vas and A. D. Sniderman. 1990. Regulation of apoB secretion from HepG2 cells; evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge. J. Lipid Res. 31:2045-2055.
    • (1990) J. Lipid Res. , vol.31 , pp. 2045-2055
    • Cianflone, K.M.1    Yasruel, Z.2    Rodriguez, M.A.3    Vas, D.4    Sniderman, A.D.5
  • 16
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • Davignon, J., R. E. Gregg and C. F. Sing. 1988. Apolipoprotein E polymorphism and atherosclerosis. Artheriosclerosis. 8:1-21.
    • (1988) Artheriosclerosis. , vol.8 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 17
    • 0020456601 scopus 로고
    • Intrahepatic assembly of very low density lipoproteins
    • Davis, R. A. and J. R. Boogaerts. 1982. Intrahepatic assembly of very low density lipoproteins. J. Biol. Chem. 257:10908-10913.
    • (1982) J. Biol. Chem. , vol.257 , pp. 10908-10913
    • Davis, R.A.1    Boogaerts, J.R.2
  • 18
    • 0022401768 scopus 로고
    • Intrahepatic assembly of very low density lipoproteins: Varied synthetic response of individual apolipoproteins to fasting
    • Davis, R. A., J. R. Boogaerts, R. A. Borchardt, M. Malone-McNeal and J. Archambault-Schexnayder. 1985. Intrahepatic assembly of very low density lipoproteins: varied synthetic response of individual apolipoproteins to fasting. J. Biol. Chem. 260:14137-14144.
    • (1985) J. Biol. Chem. , vol.260 , pp. 14137-14144
    • Davis, R.A.1    Boogaerts, J.R.2    Borchardt, R.A.3    Malone-McNeal, M.4    Archambault-Schexnayder, J.5
  • 19
    • 0030913589 scopus 로고    scopus 로고
    • Evolution of processes and regulators of lipoprotein synthesis:From birds to mammals
    • Davis, R. A. 1997. Evolution of processes and regulators of lipoprotein synthesis:from birds to mammals. J. Nutr. 127:794S-800S.
    • (1997) J. Nutr. , vol.127
    • Davis, R.A.1
  • 20
    • 0025723924 scopus 로고
    • Influence of apolipoprotein E polymorphism on apolipoprotein B-100 metabolism in normolipemic subjects
    • Demant, T., D. Bedford, C. J. Packard and J. Shepherd. 1991. Influence of apolipoprotein E polymorphism on apolipoprotein B-100 metabolism in normolipemic subjects. J. Clin. Invest. 88:1490-1501.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1490-1501
    • Demant, T.1    Bedford, D.2    Packard, C.J.3    Shepherd, J.4
  • 21
    • 0027531667 scopus 로고
    • Regulation of hepatic secretion of apolipoprotein B-containmg lipoproteins: Information obtained from cultured liver cells
    • Dixon, J. L. and H. N. Ginsberg. 1993. Regulation of hepatic secretion of apolipoprotein B-containmg lipoproteins: information obtained from cultured liver cells. J. Lipid Res. 34:167-179.
    • (1993) J. Lipid Res. , vol.34 , pp. 167-179
    • Dixon, J.L.1    Ginsberg, H.N.2
  • 22
    • 0008821336 scopus 로고    scopus 로고
    • What is gene therapy
    • (Ed. N. R. Lemoine). BIOS Scientific Publishers Limited.
    • Drew, J. and L. Martin. 1999. What is gene therapy. In Understanding Gene Therapy (Ed. N. R. Lemoine). BIOS Scientific Publishers Limited. pp. 1-10.
    • (1999) Understanding Gene Therapy , pp. 1-10
    • Drew, J.1    Martin, L.2
  • 23
    • 0021681194 scopus 로고
    • Extraheparic synthesis of apolipoprotein E
    • Driscoll, D. M. and G. S. Getz. 1984. Extraheparic synthesis of apolipoprotein E. J. Lipid Res. 25:1368-1379.
    • (1984) J. Lipid Res. , vol.25 , pp. 1368-1379
    • Driscoll, D.M.1    Getz, G.S.2
  • 26
    • 0027487995 scopus 로고
    • Rapid stimulation of apolipoprotein B secretion by oleate is not associated with cholesteryl ester synthesis in Hep G2 cells
    • Furukawa, S. and T. Hirano. 1993. Rapid stimulation of apolipoprotein B secretion by oleate is not associated with cholesteryl ester synthesis in Hep G2 cells. Biochem. Biophys. Acta. 1170:32-37.
    • (1993) Biochem. Biophys. Acta. , vol.1170 , pp. 32-37
    • Furukawa, S.1    Hirano, T.2
  • 27
    • 0022725355 scopus 로고
    • Inositol and hepatic lipidosis. I. Effect of inositol supplementation and time from parturition on liver and serum lipids in dairy cattle
    • Gerloff, B. J., T. H. Herdt, W. W. Wells, J. S. Liesman and R. S. Emery. 1986. Inositol and hepatic lipidosis. I. Effect of inositol supplementation and time from parturition on liver and serum lipids in dairy cattle. J. Anim. Sci. 62:1682-1692.
    • (1986) J. Anim. Sci. , vol.62 , pp. 1682-1692
    • Gerloff, B.J.1    Herdt, T.H.2    Wells, W.W.3    Liesman, J.S.4    Emery, R.S.5
  • 28
    • 0029033102 scopus 로고
    • Synthesis and secretion of apolipoprotein B from cultured liver cell
    • Ginsberg, H. N. 1995. Synthesis and secretion of apolipoprotein B from cultured liver cell. Curr. Opin. Lipidol. 6:275-280.
    • (1995) Curr. Opin. Lipidol. , vol.6 , pp. 275-280
    • Ginsberg, H.N.1
  • 29
    • 0030859321 scopus 로고    scopus 로고
    • Recent advances in elucidating the role of microsomal triglyceride transfer protein in apolipoprotein B lipoprotein assembly
    • Gordon, D. A. 1997. Recent advances in elucidating the role of microsomal triglyceride transfer protein in apolipoprotein B lipoprotein assembly. Curr. Opin. Lipidol. 8:131-137.
    • (1997) Curr. Opin. Lipidol. , vol.8 , pp. 131-137
    • Gordon, D.A.1
  • 31
    • 0030253703 scopus 로고    scopus 로고
    • Nutrition during the dry period alters hepatic lipid metabolism in periparturient dairy cows
    • Grum, D. E., J. K. Drackley, R. S. Younker, D. W. Lacount and J. J. Veenhuizen. 1996. Nutrition during the dry period alters hepatic lipid metabolism in periparturient dairy cows. J. Dairy Sci. 79:1850-1864.
    • (1996) J. Dairy Sci. , vol.79 , pp. 1850-1864
    • Grum, D.E.1    Drackley, J.K.2    Younker, R.S.3    Lacount, D.W.4    Veenhuizen, J.J.5
  • 32
    • 0027764872 scopus 로고
    • Etiology of lipid-related metabolic disorders in periparturient dairy cows
    • Grummer, R. R. 1993. Etiology of lipid-related metabolic disorders in periparturient dairy cows. J. Dairy Sci. 76:3882-3896.
    • (1993) J. Dairy Sci. , vol.76 , pp. 3882-3896
    • Grummer, R.R.1
  • 33
    • 0029363056 scopus 로고
    • Impact of changes in organic nutrient metabolism on feeding the transition dairy cow
    • Grummer, R. R. 1995. Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. J. Anim. Sci. 73:2820-2838.
    • (1995) J. Anim. Sci. , vol.73 , pp. 2820-2838
    • Grummer, R.R.1
  • 34
    • 0024232434 scopus 로고
    • A review of lipoprotein cholesterol metabolism:Importance to ovarian function
    • Grummer, R. R. and D. J. Carroll. 1988. A review of lipoprotein cholesterol metabolism:importance to ovarian function. J. Anim. Sci. 66:3160-3173.
    • (1988) J. Anim. Sci. , vol.66 , pp. 3160-3173
    • Grummer, R.R.1    Carroll, D.J.2
  • 35
    • 0021019991 scopus 로고
    • Comparison of ultracentrifugation and gel filtration for the isolation of bovine lipoproteins
    • Grummer, R. R., C. L. Davis and H. M. Hegarty. 1983. Comparison of ultracentrifugation and gel filtration for the isolation of bovine lipoproteins. Lipids 18:795-802.
    • (1983) Lipids , vol.18 , pp. 795-802
    • Grummer, R.R.1    Davis, C.L.2    Hegarty, H.M.3
  • 36
    • 0022018768 scopus 로고
    • Net portal absorption of lactate and volatile fatty acids in steers experiencing glucose-induced acidosis or fed a 70% concentrate diet ad libitum
    • Harmon, D. L., R. A. Britton, R. L. Prior and R. A. Stock. 1985. Net portal absorption of lactate and volatile fatty acids in steers experiencing glucose-induced acidosis or fed a 70% concentrate diet ad libitum. J. Anim. Sci. 60:560-569.
    • (1985) J. Anim. Sci. , vol.60 , pp. 560-569
    • Harmon, D.L.1    Britton, R.A.2    Prior, R.L.3    Stock, R.A.4
  • 37
    • 0032900336 scopus 로고    scopus 로고
    • Disruption of LDL receptor gene in transgenic SRBBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL
    • Horton, J. D., H. Shimano, R. L. Hamilton, M. S. Brown and J. L. Goldstein. 1999. Disruption of LDL receptor gene in transgenic SRBBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL. J. Clin. Invest. 103: 1067-1076.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1067-1076
    • Horton, J.D.1    Shimano, H.2    Hamilton, R.L.3    Brown, M.S.4    Goldstein, J.L.5
  • 39
    • 0033238035 scopus 로고    scopus 로고
    • Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis
    • Huang, Y., Ji, Z. S., Brecht, W. J., S. C. Jr. Rall, J. M. Taylor and R. W. Mahley. 1999. Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis. Arterioscler Thromb Vasc Biol. 19:2952-2959.
    • (1999) Arterioscler Thromb Vasc Biol. , vol.19 , pp. 2952-2959
    • Huang, Y.1    Ji, Z.S.2    Brecht, W.J.3    Rall S.C., Jr.4    Taylor, J.M.5    Mahley, R.W.6
  • 40
    • 0021685314 scopus 로고
    • Binding of chylomicron remnants and β-VLDL to hepatic and extrahepatic lipoprotein receptors
    • Hui, D. Y. T. L. Innerarity, R. W. Milne, Y. L. Marcel and R. W. Mahley. 1984. Binding of chylomicron remnants and β-VLDL to hepatic and extrahepatic lipoprotein receptors. J. Biol. Chem. 259:15060-15068.
    • (1984) J. Biol. Chem. , vol.259 , pp. 15060-15068
    • Hui, D.Y.1    Innerarity, T.L.2    Milne, R.W.3    Marcel, Y.L.4    Mahley, R.W.5
  • 41
    • 0032802253 scopus 로고    scopus 로고
    • The mammalian low-density lipoprotein receptor family
    • Hussain, M. M., D. K. Strickland and A. Bakillah. 1999. The mammalian low-density lipoprotein receptor family. Annu. Rev. Nutr. 19:141-172.
    • (1999) Annu. Rev. Nutr. , vol.19 , pp. 141-172
    • Hussain, M.M.1    Strickland, D.K.2    Bakillah, A.3
  • 42
    • 0029993847 scopus 로고    scopus 로고
    • Apolipoprotein B-100 destined for lipoprotein assembly and intracellular degradation undergoes efficient translocation across the endoplasmic reticulum membrane
    • Ingram, M. F. and G. S. Shelness. 1996. Apolipoprotein B-100 destined for lipoprotein assembly and intracellular degradation undergoes efficient translocation across the endoplasmic reticulum membrane. J. Lipid Res. 37:2202-2214.
    • (1996) J. Lipid Res. , vol.37 , pp. 2202-2214
    • Ingram, M.F.1    Shelness, G.S.2
  • 44
    • 0031874552 scopus 로고    scopus 로고
    • Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells
    • Jamil, H., C. H. Chu, J. K. Jr. Dickson, Y. Chen, M. Yan, S. A. Biller, R. E. Gregg, J. R. Wetterau and D. A. Gordon. 1998. Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells. J. Lipid Res. 39:1448-1454.
    • (1998) J. Lipid Res. , vol.39 , pp. 1448-1454
    • Jamil, H.1    Chu, C.H.2    Dickson J.K., Jr.3    Chen, Y.4    Yan, M.5    Biller, S.A.6    Gregg, R.E.7    Wetterau, J.R.8    Gordon, D.A.9
  • 45
    • 0028302931 scopus 로고
    • Effect of dietary addition of myo-inositol on lipid metabolism in rats fed sucrose or corn starch
    • Katayama, T. 1994. Effect of dietary addition of myo-inositol on lipid metabolism in rats fed sucrose or corn starch. Nutr. Res. 14:699-706.
    • (1994) Nutr. Res. , vol.14 , pp. 699-706
    • Katayama, T.1
  • 46
    • 0027374578 scopus 로고
    • Effect of estradiol administration and subsequent nonfeeding on liver estrogen receptor, serum apolipoprotein B-100 and serum triglycerides concentrations in steers
    • Katoh, N., S. Minoura, E. Uchida and K. Takahashi. 1993. Effect of estradiol administration and subsequent nonfeeding on liver estrogen receptor, serum apolipoprotein B-100 and serum triglycerides concentrations in steers. Am. J. Vet. Res. 54:1476-1482.
    • (1993) Am. J. Vet. Res. , vol.54 , pp. 1476-1482
    • Katoh, N.1    Minoura, S.2    Uchida, E.3    Takahashi, K.4
  • 48
    • 0024043996 scopus 로고
    • Triglyceride accumulation and very low density lipoprotein secretion by rat and goat hepatocytes in vitro
    • Kleppe, B. B., R. J. Aiello, R. R. Grummer and L. E. Armentano, 1988. Triglyceride accumulation and very low density lipoprotein secretion by rat and goat hepatocytes in vitro. J. Dairy Sci. 71:1813-1822.
    • (1988) J. Dairy Sci. , vol.71 , pp. 1813-1822
    • Kleppe, B.B.1    Aiello, R.J.2    Grummer, R.R.3    Armentano, L.E.4
  • 49
    • 0029610830 scopus 로고
    • Role of neutral lipid accessible pool in the regulation of secretion of apo B-100 lipoprotein particles by HepG2 cells
    • Kohen, A. R., K. Cianflone and A. D. Sniderman. 1995. Role of neutral lipid accessible pool in the regulation of secretion of apo B-100 lipoprotein particles by HepG2 cells. J. Lipid Res. 36:2513-2528.
    • (1995) J. Lipid Res. , vol.36 , pp. 2513-2528
    • Kohen, A.R.1    Cianflone, K.2    Sniderman, A.D.3
  • 52
    • 0023898940 scopus 로고
    • Apolipoprotein gene expression in the rabbit: Abundance, size and distribution of apolipoprotein mRNA species in different tissues
    • Lenich, C., P. Brecher, S. Makrides, A. Chobanian and VI. Zannis. 1988. Apolipoprotein gene expression in the rabbit: abundance, size and distribution of apolipoprotein mRNA species in different tissues. J. Lipid Res. 29:755-764.
    • (1988) J. Lipid Res. , vol.29 , pp. 755-764
    • Lenich, C.1    Brecher, P.2    Makrides, S.3    Chobanian, A.4    Zannis, V.I.5
  • 53
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley, R. W. 1988. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Sci. 240:622-630.
    • (1988) Sci. , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 54
    • 0032895028 scopus 로고    scopus 로고
    • Remnant lipoprotein metabolism:Key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E
    • Mahley, R. W. and Z. S. Ji. 1999. Remnant lipoprotein metabolism:key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E. J. Lipid Res. 40:1-16.
    • (1999) J. Lipid Res. , vol.40 , pp. 1-16
    • Mahley, R.W.1    Ji, Z.S.2
  • 58
    • 0034202522 scopus 로고    scopus 로고
    • Inclusion of the hepatic locus control region, an intron, and untranslated region increases and stabilizes hepatic factor IX gene expression in vivo but not in vitro
    • Miao, C. H., K. Ohashi, G. A. Patijn, L. Meuse, X. Ye, A. R. Thompson and M. A. Kay. 2000. Inclusion of the hepatic locus control region, an intron, and untranslated region increases and stabilizes hepatic factor IX gene expression in vivo but not in vitro. Molecular Therapy 1(6):522-532
    • (2000) Molecular Therapy , vol.1 , Issue.6 , pp. 522-532
    • Miao, C.H.1    Ohashi, K.2    Patijn, G.A.3    Meuse, L.4    Ye, X.5    Thompson, A.R.6    Kay, M.A.7
  • 59
    • 0034104640 scopus 로고    scopus 로고
    • Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system
    • Nishikawa, M., M. Yamauchi, K. Morimoto, E. Ishida, Y. Takakura and M Hashida. 2000. Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system. Gene Therapy 7:548-555.
    • (2000) Gene Therapy , vol.7 , pp. 548-555
    • Nishikawa, M.1    Yamauchi, M.2    Morimoto, K.3    Ishida, E.4    Takakura, Y.5    Hashida, M.6
  • 60
    • 0030054587 scopus 로고    scopus 로고
    • Regulation of hepatic apolipoprotein B-containing lipoprotein secretion
    • Pease, R. J. and J. M. Leiper. 1996. Regulation of hepatic apolipoprotein B-containing lipoprotein secretion. Curr. Opin. Lipidol. 7:132-138.
    • (1996) Curr. Opin. Lipidol. , vol.7 , pp. 132-138
    • Pease, R.J.1    Leiper, J.M.2
  • 61
    • 0025427649 scopus 로고    scopus 로고
    • A species comparison of liver slice synthesis and secretion of triacylglycerol from nonesterifies fatty acids in media
    • 19990
    • Pullen, D. L., J. S. Liesman and R. S. Emery. 19990. A species comparison of liver slice synthesis and secretion of triacylglycerol from nonesterifies fatty acids in media. J. Anim. Sc. 68:1395-1399.
    • J. Anim. Sc. , vol.68 , pp. 1395-1399
    • Pullen, D.L.1    Liesman, J.S.2    Emery, R.S.3
  • 62
    • 0027535128 scopus 로고
    • Assembly of rat hepatic very low density lipoproteins in endoplasmic reticulum
    • Rusinol, A. E., H. J. Verkade and J. E. Vance. 1993. Assembly of rat hepatic very low density lipoproteins in endoplasmic reticulum. J. Biol. Chem. 268:3555-3562.
    • (1993) J. Biol. Chem. , vol.268 , pp. 3555-3562
    • Rusinol, A.E.1    Verkade, H.J.2    Vance, J.E.3
  • 64
    • 0032927776 scopus 로고    scopus 로고
    • Apolipoprotein B in the rough endoplasmic reticulum: Translation, translocatiion and the initiation of lipoprotein assembly
    • Shelness, G. S., M. F. Ingram, X. F. Huang and J. A. Delozier. 1999. Apolipoprotein B in the rough endoplasmic reticulum: translation, translocatiion and the initiation of lipoprotein assembly. J. Nutr .129:456S-462S.
    • (1999) J. Nutr . , vol.129
    • Shelness, G.S.1    Ingram, M.F.2    Huang, X.F.3    Delozier, J.A.4
  • 65
    • 0019153305 scopus 로고
    • Rapid hepatic clearance of the canine lipoproteins containing only the E apoprotein by a high affinity receptor
    • Sherill, B. C., T. L. Innerarity and R. W. Mahley. 1980. Rapid hepatic clearance of the canine lipoproteins containing only the E apoprotein by a high affinity receptor. J. Biol. Chem. 255: 1804-1807.
    • (1980) J. Biol. Chem. , vol.255 , pp. 1804-1807
    • Sherill, B.C.1    Innerarity, T.L.2    Mahley, R.W.3
  • 66
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SRBBP-1a
    • Shirnano, H., J. D. Horton, R. E. Hammer, I. Shimomura, M. S. Brown and J. L. Goldstein. 1996. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SRBBP-1a. J. Clin. Invest. 98:1575-1584.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1575-1584
    • Shirnano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 67
    • 0024708667 scopus 로고
    • Seasonal effects of prepartum and postpartum fat and niacin feeding on lactation performance and lipid metabolism
    • Skaar, T. C., R. R. Grummer, M. R. Dentine and R. H. Stauffacher. 1989. Seasonal effects of prepartum and postpartum fat and niacin feeding on lactation performance and lipid metabolism. J. Dairy Sci. 72:2028-2038.
    • (1989) J. Dairy Sci. , vol.72 , pp. 2028-2038
    • Skaar, T.C.1    Grummer, R.R.2    Dentine, M.R.3    Stauffacher, R.H.4
  • 68
    • 0032789462 scopus 로고    scopus 로고
    • Gene therapy-where are we?
    • Smith, A. E. 1999. Gene therapy-where are we? Molecular Medicine 354(suppl.1):1-4.
    • (1999) Molecular Medicine , vol.354 , Issue.1 SUPPL. , pp. 1-4
    • Smith, A.E.1
  • 69
    • 0027155457 scopus 로고
    • Hormonal regulation of lipoprotein assembly and secretion
    • Sparks, J. D. and C. E. Sparks. 1993. Hormonal regulation of lipoprotein assembly and secretion. Curr. Opin. Lipidol. 4:177-186.
    • (1993) Curr. Opin. Lipidol. , vol.4 , pp. 177-186
    • Sparks, J.D.1    Sparks, C.E.2
  • 70
    • 0032524616 scopus 로고    scopus 로고
    • Selective uptake of low density lipoprotein-cholesteryl ester is enhanced by inducible apolipoprotein E expression in cultured mouse adrenocortical cells
    • Swarnakar, S., M. E. Reyland, J. Deng, S. Azhar and D. L. Williams. 1998. Selective uptake of low density lipoprotein-cholesteryl ester is enhanced by inducible apolipoprotein E expression in cultured mouse adrenocortical cells. J. Biol. Chem. 273:12140-12147.
    • (1998) J. Biol. Chem. , vol.273 , pp. 12140-12147
    • Swarnakar, S.1    Reyland, M.E.2    Deng, J.3    Azhar, S.4    Williams, D.L.5
  • 71
    • 0032717454 scopus 로고    scopus 로고
    • Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B
    • Tietge, U. J. F., A. Bakillah, C. Mangeais, K. Tsukamoto, M. Hussain and D. J. Rader. 1999. Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B. J. Lipid Res. 40: 2134-2139.
    • (1999) J. Lipid Res. , vol.40 , pp. 2134-2139
    • Tietge, U.J.F.1    Bakillah, A.2    Mangeais, C.3    Tsukamoto, K.4    Hussain, M.5    Rader, D.J.6
  • 72
    • 0033999663 scopus 로고    scopus 로고
    • Markedly increased secretion of VLDL triglycerides induced by gene transfer of apolipoprotein E isoforms in apoE-deficient mice
    • Tsukamoto, K., C. Maugeais, J. M. Click and D. J. Rader. 2000. Markedly increased secretion of VLDL triglycerides induced by gene transfer of apolipoprotein E isoforms in apoE-deficient mice. J. Lipid Res. 41:253-259.
    • (2000) J. Lipid Res. , vol.41 , pp. 253-259
    • Tsukamoto, K.1    Maugeais, C.2    Click, J.M.3    Rader, D.J.4
  • 74
    • 0026483805 scopus 로고
    • Induction of fatty liver in cows by ethionine administration and concomitant decreases of serum lipoproteins B-100 and A-1 concentrations
    • Uchida, E., N. Katoh and K. Takahashi. 1992. Induction of fatty liver in cows by ethionine administration and concomitant decreases of serum lipoproteins B-100 and A-1 concentrations. Am. J. Vet. Res. 53:2035-2042.
    • (1992) Am. J. Vet. Res. , vol.53 , pp. 2035-2042
    • Uchida, E.1    Katoh, N.2    Takahashi, K.3
  • 76
    • 0029852240 scopus 로고    scopus 로고
    • In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2 (Arg-158→Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice
    • Van Vlijmen, B. J., K. W. van Dijk, H. B. van't Hof, P. J. van Gorp, A. van der Zee, H. van der Boom, M. L. breuer, M. H. Hofker, and L. M. Havekes. 1996. In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2 (Arg-158→Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice. J. Biol. Chem. 271:30595-30602.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30595-30602
    • Van Vlijmen, B.J.1    Van Dijk, K.W.2    Van't Hof, H.B.3    Van Gorp, P.J.4    Van Der Zee, A.5    Van Der Boom, H.6    Breuer, M.L.7    Hofker, M.H.8    Havekes, L.M.9
  • 78
    • 0027484196 scopus 로고
    • Impaired biosynthesis of phosphatidylcholine causes a decrease in the number of very low density lipoprotein particles in the Golgi but not in the endoplasmic reticulum of rat liver
    • Verkade, H. J., D. G. Fast, A. E. Rusinol, D. G. Scraba and D. E. Vance. 1993. Impaired biosynthesis of phosphatidylcholine causes a decrease in the number of very low density lipoprotein particles in the Golgi but not in the endoplasmic reticulum of rat liver. J. Biol. Chem. 268:24990-24996.
    • (1993) J. Biol. Chem. , vol.268 , pp. 24990-24996
    • Verkade, H.J.1    Fast, D.G.2    Rusinol, A.E.3    Scraba, D.G.4    Vance, D.E.5
  • 79
    • 0025329901 scopus 로고
    • Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex
    • Wetterau, J. R., A. Combs, S. N. Spinner and B. J. Joiner. 1990. Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex. J. Biol. Chem. 265:9801-9807.
    • (1990) J. Biol. Chem. , vol.265 , pp. 9801-9807
    • Wetterau, J.R.1    Combs, A.2    Spinner, S.N.3    Joiner, B.J.4
  • 80
    • 0028365288 scopus 로고
    • Evidence for a lack of regulation of assembly and secretion of apolipoprotein B-containing lipoprotein from HepG2 cells by cholesteryl ester
    • Wu, X., N. Sakata, E. Liu and H. N. Ginsberg. 1994. Evidence for a lack of regulation of assembly and secretion of apolipoprotein B-containing lipoprotein from HepG2 cells by cholesteryl ester. J. Biol. Chem. 269:12375-12382.
    • (1994) J. Biol. Chem. , vol.269 , pp. 12375-12382
    • Wu, X.1    Sakata, N.2    Liu, E.3    Ginsberg, H.N.4
  • 81
    • 0032949030 scopus 로고    scopus 로고
    • Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer
    • F. C. Jr.
    • Ye, X., V. M. Rivera, P. Zoltick, F. C. Jr., M. A. Schnell, G. Gao, J. V. Hughes, M. Gilman and J. M. Wilson. 1999. Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer. Science 283:88-91.
    • (1999) Science , vol.283 , pp. 88-91
    • Ye, X.1    Rivera, V.M.2    Zoltick, P.3    Schnell, M.A.4    Gao, G.5    Hughes, J.V.6    Gilman, M.7    Wilson, J.M.8
  • 82
    • 0028303299 scopus 로고
    • Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins
    • Yao, Z. and R. S. Mcleod. 1994. Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins. Biochem. Biophys. Acta. 1212:152-166.
    • (1994) Biochem. Biophys. Acta. , vol.1212 , pp. 152-166
    • Yao, Z.1    Mcleod, R.S.2
  • 83
    • 0030725291 scopus 로고    scopus 로고
    • Intracellular degradation of newly synthesized apolipoprotein B
    • Yao, Z., K. Ttan and R. S. Mcleod. 1997. Intracellular degradation of newly synthesized apolipoprotein B. J. Lipid Res. 38:1937-1953.
    • (1997) J. Lipid Res. , vol.38 , pp. 1937-1953
    • Yao, Z.1    Ttan, K.2    Mcleod, R.S.3
  • 84
    • 0023003519 scopus 로고
    • Apo E distribution among lipoproteins of Rhesus monkeys is modulated by dietary fat and cholesterol
    • Zanni, E. E., Z. F. Stephan, V. I. Zannis, J. L. Breslow and K. C. Hayes. 1986. Apo E distribution among lipoproteins of Rhesus monkeys is modulated by dietary fat and cholesterol. J. Nutr. 116:1611-1619.
    • (1986) J. Nutr. , vol.116 , pp. 1611-1619
    • Zanni, E.E.1    Stephan, Z.F.2    Zannis, V.I.3    Breslow, J.L.4    Hayes, K.C.5
  • 85
    • 0033893570 scopus 로고    scopus 로고
    • Long-term expression of human alpha1-antitrypsin gene in mouse liver achieved by intravenous administration of plasmid DNA using a hydrodynamics-based procedure
    • Zhang, G., Y. K. Song and D. Liu. 2000. Long-term expression of human alpha1-antitrypsin gene in mouse liver achieved by intravenous administration of plasmid DNA using a hydrodynamics-based procedure. Gene Therapy 7:1344-1349.
    • (2000) Gene Therapy , vol.7 , pp. 1344-1349
    • Zhang, G.1    Song, Y.K.2    Liu, D.3


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