Structures of an ActRIIB:activin a complex reveal a novel binding mode for TGF-β ligand:receptor interactions

EMBO Journal

Volumn 22, Issue 7, 2003, Pages 1555-1566

  Thompson, Thomas B ^a   Woodruff, Teresa K ^a   Jardetzky, Theodore S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Activin; ActRIIB; Receptors; Signaling; Structure; TGF

Indexed keywords

ACTIVIN A; ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR 2B ACTIVIN A COMPLEX; DIMER; ISOPROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; COMPLEX FORMATION; CRYSTAL STRUCTURE; EXTRACELLULAR SPACE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ACTIVIN RECEPTORS, TYPE II; ACTIVINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; INHIBIN-BETA SUBUNITS; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA;

EID: 0345269804     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg156     Document Type: Article

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