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Volumn 27, Issue , 1996, Pages 41-64

Serine/threonine kinase receptors: Mediators of transforming growth factor beta family signals

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE; RECEPTOR SUBUNIT; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 0029904671     PISSN: 02612429     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (196)

References (130)
  • 1
    • 0028953810 scopus 로고
    • Transforming growth factor β and cell cycle regulation
    • Alexandrow MG and Moses HL (1995) Transforming growth factor β and cell cycle regulation. Cancer Research 55 1452-1457
    • (1995) Cancer Research , vol.55 , pp. 1452-1457
    • Alexandrow, M.G.1    Moses, H.L.2
  • 2
    • 0024792629 scopus 로고
    • Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-β
    • Andres JL, Stanley K, Cheifetz S and Massagué J (1989) Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-β. Journal of Biological Chemistry 109 3137-3145
    • (1989) Journal of Biological Chemistry , vol.109 , pp. 3137-3145
    • Andres, J.L.1    Stanley, K.2    Cheifetz, S.3    Massagué, J.4
  • 3
    • 0029072998 scopus 로고
    • The Drosophila schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family
    • Arora K, Dai H, Kazuko SG et al (1995) The Drosophila schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family. Cell 81 781-790
    • (1995) Cell , vol.81 , pp. 781-790
    • Arora, K.1    Dai, H.2    Kazuko, S.G.3
  • 4
    • 0026527384 scopus 로고
    • Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
    • Attisano L, Wrana JL, Cheifetz S and Massagué J (1992) Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors. Cell 68 97-108
    • (1992) Cell , vol.68 , pp. 97-108
    • Attisano, L.1    Wrana, J.L.2    Cheifetz, S.3    Massagué, J.4
  • 5
    • 0027525105 scopus 로고
    • Identification of human activin and TGF-β type I receptors that form heteromeric kinase complexes with type II receptors
    • Attisano L, Cárcamo J, Ventura F et al (1993) Identification of human activin and TGF-β type I receptors that form heteromeric kinase complexes with type II receptors. Cell 75 671-680
    • (1993) Cell , vol.75 , pp. 671-680
    • Attisano, L.1    Cárcamo, J.2    Ventura, F.3
  • 7
    • 0027953410 scopus 로고
    • A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the Müllerian duct
    • Baarens WM, van Helmaond MJL, Post M et al (1994) A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the Müllerian duct. Development 120 189-197
    • (1994) Development , vol.120 , pp. 189-197
    • Baarens, W.M.1    Van Helmaond, M.J.L.2    Post, M.3
  • 8
    • 0028267256 scopus 로고
    • A transforming growth factor β type I receptor that signals to activate gene expression
    • Bassing CH, Yingling JM, Howe DJ et al (1994) A transforming growth factor β type I receptor that signals to activate gene expression. Science 263 87-89
    • (1994) Science , vol.263 , pp. 87-89
    • Bassing, C.H.1    Yingling, J.M.2    Howe, D.J.3
  • 9
    • 0026778310 scopus 로고
    • Transforming growth factor-β in disease: The dark side of tissue repair
    • Border WA and Ruoslahti E (1992) Transforming growth factor-β in disease: the dark side of tissue repair. Journal of Clinical Investigation 90 1-7
    • (1992) Journal of Clinical Investigation , vol.90 , pp. 1-7
    • Border, W.A.1    Ruoslahti, E.2
  • 10
    • 0024538265 scopus 로고
    • Growth inhibitory response to transforming growth factor-β linked to expression of a 53 kDa cell surface TGF-β receptor
    • Boyd FT and Massagué J (1989) Growth inhibitory response to transforming growth factor-β linked to expression of a 53 kDa cell surface TGF-β receptor. Journal of Biological Chemistry 264 2272-2278
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 2272-2278
    • Boyd, F.T.1    Massagué, J.2
  • 11
    • 0028910192 scopus 로고
    • Inactive type II and type I receptors for TGF beta are dominant inhibitors of TGF-beta-dependent transcription
    • Brand T and Schneider MD (1995) Inactive type II and type I receptors for TGF beta are dominant inhibitors of TGF-beta-dependent transcription. Journal of Biological Chemistry 270 8274-8284
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 8274-8284
    • Brand, T.1    Schneider, M.D.2
  • 12
    • 0027300034 scopus 로고
    • A dominant-negative receptor for type βtransforming growth factor created by deletion of the kinase domain
    • Brand T, MacLelland WR and Schneider MD (1993) A dominant-negative receptor for type βtransforming growth factor created by deletion of the kinase domain. Journal of Biological Chemistry 268 11500-11503
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 11500-11503
    • Brand, T.1    MacLelland, W.R.2    Schneider, M.D.3
  • 13
    • 0028103859 scopus 로고
    • Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila
    • Brummel T, Twombly V, Marques G et al (1994) Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila. Cell 78 251-261
    • (1994) Cell , vol.78 , pp. 251-261
    • Brummel, T.1    Twombly, V.2    Marques, G.3
  • 14
    • 0028359376 scopus 로고
    • Type I receptors specify growth inhibitory and transcriptional responses to TGF-β and activin
    • Cárcamo J, Weis FMB, Ventura F et al (1994) Type I receptors specify growth inhibitory and transcriptional responses to TGF-β and activin. Molecular and Cellular Biology 14 3810-3821
    • (1994) Molecular and Cellular Biology , vol.14 , pp. 3810-3821
    • Cárcamo, J.1    Weis, F.M.B.2    Ventura, F.3
  • 15
    • 0028894025 scopus 로고
    • Disruption of TGF-β signaling by a mutation that prevents transphosphorylation within the receptor complex
    • Cárcamo J, Zentella A and Massagué J (1995) Disruption of TGF-β signaling by a mutation that prevents transphosphorylation within the receptor complex. Molecular and Cellular Biology 15 1573-1581
    • (1995) Molecular and Cellular Biology , vol.15 , pp. 1573-1581
    • Cárcamo, J.1    Zentella, A.2    Massagué, J.3
  • 16
    • 0022499726 scopus 로고
    • Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells
    • Cate RL, Mattaliano RJ, Hession C et al (1986) Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells. Cell 45 685-698
    • (1986) Cell , vol.45 , pp. 685-698
    • Cate, R.L.1    Mattaliano, R.J.2    Hession, C.3
  • 17
    • 0023652332 scopus 로고
    • The transforming growth factor-β system, a complex pattern of crossreactive ligands and receptors
    • Cheifetz S, Weatherbee JA, Tsang ML-S et al (1987) The transforming growth factor-β system, a complex pattern of crossreactive ligands and receptors. Cell 48 409-415
    • (1987) Cell , vol.48 , pp. 409-415
    • Cheifetz, S.1    Weatherbee, J.A.2    Tsang, M.L.-S.3
  • 18
    • 0026646785 scopus 로고
    • Endoglin is a component of the TGF-β receptor system in human endothelial cells
    • Cheifetz S, Bellón T, Calés C et al (1992) Endoglin is a component of the TGF-β receptor system in human endothelial cells. Journal of Biological Chemistry 267 19027-19030
    • (1992) Journal of Biological Chemistry , vol.267 , pp. 19027-19030
    • Cheifetz, S.1    Bellón, T.2    Calés, C.3
  • 19
    • 0028937160 scopus 로고
    • Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor β receptor kinases
    • Chen F and Weinberg RA (1995) Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor β receptor kinases. Proceedings of the National Academy of Sciences of the USA 92 1565-1569
    • (1995) Proceedings of the National Academy of Sciences of the USA , vol.92 , pp. 1565-1569
    • Chen, F.1    Weinberg, R.A.2
  • 20
    • 0028059199 scopus 로고
    • Homomeric interactions between type II transforming growth factor-β receptors
    • Chen R-H and Derynck R (1994) Homomeric interactions between type II transforming growth factor-β receptors. Journal of Biological Chemistry 269 22868-22874
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 22868-22874
    • Chen, R.-H.1    Derynck, R.2
  • 21
    • 0027250810 scopus 로고
    • Inactivation of type II receptor reveals two receptor pathways for the diverse TGF-β activities
    • Chen R-H, Ebner R and Derynck R (1993) Inactivation of type II receptor reveals two receptor pathways for the diverse TGF-β activities. Science 260 1335-1338
    • (1993) Science , vol.260 , pp. 1335-1338
    • Chen, R.-H.1    Ebner, R.2    Derynck, R.3
  • 22
    • 0029157432 scopus 로고
    • A WD-domain protein that is associated with and phosphorylated by the type II TGF-β receptor
    • Chen R-H, Miettinen PJ, Maruoka EM, Choy L and Derynck R (1995a) A WD-domain protein that is associated with and phosphorylated by the type II TGF-β receptor. Nature 377 548-552
    • (1995) Nature , vol.377 , pp. 548-552
    • Chen, R.-H.1    Miettinen, P.J.2    Maruoka, E.M.3    Choy, L.4    Derynck, R.5
  • 23
    • 0029010192 scopus 로고
    • Phosphorylation-dependent interaction of the cytoplasmic domains of the type I and type II transforming growth factor-β receptors
    • Chen R-H, Moses HL, Maruoka EM, Derynck R and Kawabata M (1995b) Phosphorylation-dependent interaction of the cytoplasmic domains of the type I and type II transforming growth factor-β receptors. Journal of Biological Chemistry 270 12235-12241
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 12235-12241
    • Chen, R.-H.1    Moses, H.L.2    Maruoka, E.M.3    Derynck, R.4    Kawabata, M.5
  • 25
    • 0027943249 scopus 로고
    • Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle
    • Daksis JI, Lu RY, Facchini LM and Marhin WW (1994) Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle. Oncogene 9 3635-3645
    • (1994) Oncogene , vol.9 , pp. 3635-3645
    • Daksis, J.I.1    Lu, R.Y.2    Facchini, L.M.3    Marhin, W.W.4
  • 26
    • 0029073142 scopus 로고
    • Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanisms
    • Datto MB, Li Y, Panus JF et al (1995a) Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanisms. Proceedings of the National Academy of Sciences of the USA 92 5545-5549
    • (1995) Proceedings of the National Academy of Sciences of the USA , vol.92 , pp. 5545-5549
    • Datto, M.B.1    Li, Y.2    Panus, J.F.3
  • 27
    • 0028829465 scopus 로고
    • Functional analysis of the transforming growth factor β responsive elements in WAF1/Cip1/p21 promoter
    • Datto MB, Yu Y and Wang X-F (1995b) Functional analysis of the transforming growth factor β responsive elements in WAF1/Cip1/p21 promoter. Journal of Biological Chemistry 270 28623-28628
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 28623-28628
    • Datto, M.B.1    Yu, Y.2    Wang, X.-F.3
  • 28
    • 0028106201 scopus 로고
    • Cloning expression and alternative splicing of the receptor for anti-Müllerian hormone
    • di Clemente N, Wilson C, Faure E et al (1994) Cloning expression and alternative splicing of the receptor for anti-Müllerian hormone. Molecular Endocrinology 8 1006-1020
    • (1994) Molecular Endocrinology , vol.8 , pp. 1006-1020
    • Di Clemente, N.1    Wilson, C.2    Faure, E.3
  • 29
    • 0027219671 scopus 로고
    • Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor
    • Ebner R, Chen R-H, Shum L et al (1993) Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor. Science 260 1344-1348
    • (1993) Science , vol.260 , pp. 1344-1348
    • Ebner, R.1    Chen, R.-H.2    Shum, L.3
  • 30
    • 0027373733 scopus 로고
    • The daf-4 gene encodes a bone morphogenetic protein receptor controlling C elegans larva development
    • Estevez M, Attisano L, Wrana JL et al (1993) The daf-4 gene encodes a bone morphogenetic protein receptor controlling C elegans larva development. Nature 365 644-649
    • (1993) Nature , vol.365 , pp. 644-649
    • Estevez, M.1    Attisano, L.2    Wrana, J.L.3
  • 31
    • 0027374766 scopus 로고
    • TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest
    • Ewen ME, Sluss HK, Whitehouse LL and Livingston DM (1993) TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74 1009-1020
    • (1993) Cell , vol.74 , pp. 1009-1020
    • Ewen, M.E.1    Sluss, H.K.2    Whitehouse, L.L.3    Livingston, D.M.4
  • 32
    • 0028972072 scopus 로고
    • Transforming growth factor-β (TGF-β)-induced down regulation of cyclin A expression requires a functional TGF-β receptor complex
    • Feng X-H, Filvaroff EH, Derynck R (1995) Transforming growth factor-β (TGF-β)-induced down regulation of cyclin A expression requires a functional TGF-β receptor complex. Journal of Biological Chemistry 270 24237-24245
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 24237-24245
    • Feng, X.-H.1    Filvaroff, E.H.2    Derynck, R.3
  • 33
    • 0027332995 scopus 로고
    • Cloning of a TGF-β type I receptor that forms a heteromeric complex with the TGF-β type II receptor
    • Franzén P, ten Dijke P, Ichijo H et al (1993) Cloning of a TGF-β type I receptor that forms a heteromeric complex with the TGF-β type II receptor. Cell 75 681-692
    • (1993) Cell , vol.75 , pp. 681-692
    • Franzén, P.1    Ten Dijke, P.2    Ichijo, H.3
  • 34
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis
    • Fynan TM and Reiss M (1993) Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis. Critical Reviews in Oncogenesis 4 493-540
    • (1993) Critical Reviews in Oncogenesis , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 35
    • 0029114477 scopus 로고
    • Missense mutations in the transforming growth factor β type II receptor in human head and neck squamous cell carcinomas
    • Garrigue-Antar L, Muñoz-Antonia T, Antonia SJ et al (1995) Missense mutations in the transforming growth factor β type II receptor in human head and neck squamous cell carcinomas. Cancer Research 55 3982-3987
    • (1995) Cancer Research , vol.55 , pp. 3982-3987
    • Garrigue-Antar, L.1    Muñoz-Antonia, T.2    Antonia, S.J.3
  • 36
    • 0027500836 scopus 로고
    • Tranforming growth factor β1 (TGF-β1) controls expression of major histocompatibility genes in the postnatal mouse: Aberrant histocompatibility antigen expression in the pathogenesis of the TGF-β1 null mouse phenotype
    • Geiser AG, Letterio JJ, Kulkarni AB et al (1993) Tranforming growth factor β1 (TGF-β1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-β1 null mouse phenotype. Proceedings of the National Academy of Sciences of the USA 90 9944-9948
    • (1993) Proceedings of the National Academy of Sciences of the USA , vol.90 , pp. 9944-9948
    • Geiser, A.G.1    Letterio, J.J.2    Kulkarni, A.B.3
  • 37
    • 0025281396 scopus 로고
    • daf-1 a C elegans gene controlling dauer larva development, encodes a novel receptor protein kinase
    • Georgi LL, Albert PS and Riddle DL (1990) daf-1 a C elegans gene controlling dauer larva development, encodes a novel receptor protein kinase. Cell 61 635-645
    • (1990) Cell , vol.61 , pp. 635-645
    • Georgi, L.L.1    Albert, P.S.2    Riddle, D.L.3
  • 38
    • 0028331587 scopus 로고
    • Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic
    • Gibbs JB, Oliff A and Kohl NE (1994) Farnesyltransferase inhibitors: ras research yields a potential cancer therapeutic. Cell 77 175-178
    • (1994) Cell , vol.77 , pp. 175-178
    • Gibbs, J.B.1    Oliff, A.2    Kohl, N.E.3
  • 39
    • 0028171401 scopus 로고
    • Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma
    • Glick AB, Lee MM, Darwiche N et al (1994) Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma. Genes and Development 8 2429-2440
    • (1994) Genes and Development , vol.8 , pp. 2429-2440
    • Glick, A.B.1    Lee, M.M.2    Darwiche, N.3
  • 40
    • 0025310515 scopus 로고
    • Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells
    • Gougos A and Letarte M (1990) Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells. Journal of Biological Chemistry 265 8361-8364
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 8361-8364
    • Gougos, A.1    Letarte, M.2
  • 41
    • 0028170038 scopus 로고
    • Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
    • Graff JM, Thies RS, Song JJ, Celeste AJ and Melton DA (1994) Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79 169-179
    • (1994) Cell , vol.79 , pp. 169-179
    • Graff, J.M.1    Thies, R.S.2    Song, J.J.3    Celeste, A.J.4    Melton, D.A.5
  • 42
    • 0028990126 scopus 로고
    • Shnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1
    • Grieder NC, Nellen D, Burke R, Basler K and Affolter M (1995) shnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell 81 791-800
    • (1995) Cell , vol.81 , pp. 791-800
    • Grieder, N.C.1    Nellen, D.2    Burke, R.3    Basler, K.4    Affolter, M.5
  • 43
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon GJ and Beach D (1994) p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371 257-261
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 44
    • 0028053916 scopus 로고
    • The transforming growth factor β family and induction of vertebrate mesoderm: Bone morphogenetic proteins are ventral inducers
    • Harland RM (1994) The transforming growth factor β family and induction of vertebrate mesoderm: bone morphogenetic proteins are ventral inducers. Proceedings of the National Academy of Sciences of the USA 91 10243-10246
    • (1994) Proceedings of the National Academy of Sciences of the USA , vol.91 , pp. 10243-10246
    • Harland, R.M.1
  • 45
    • 0028291369 scopus 로고
    • The type II and III transforming growth factor-β receptors form homo-oligomers
    • Henis YI, Moustakas A, Lin HY and Lodish HF (1994) The type II and III transforming growth factor-β receptors form homo-oligomers. Journal of Cell Biology 126 139-154
    • (1994) Journal of Cell Biology , vol.126 , pp. 139-154
    • Henis, Y.I.1    Moustakas, A.2    Lin, H.Y.3    Lodish, H.F.4
  • 48
    • 0027938209 scopus 로고
    • Cylins and cancer II: Cyclin D and CDK inhibitiors come of age
    • Hunter T and Pines J (1994) Cylins and cancer II: cyclin D and CDK inhibitiors come of age. Cell 79 573-582
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 49
    • 0028972867 scopus 로고
    • Insensitivity to anti-Müllerian hormone due to a mutation in the human anti-Müllerian hormone receptor
    • Imbeaud S, Faure E, Lamarre I et al (1995) Insensitivity to anti-Müllerian hormone due to a mutation in the human anti-Müllerian hormone receptor. Nature Genetics 11 382-388
    • (1995) Nature Genetics , vol.11 , pp. 382-388
    • Imbeaud, S.1    Faure, E.2    Lamarre, I.3
  • 50
    • 0027164326 scopus 로고
    • Growth inhibition by transforming growth factor-β (TGF-β) is restored in TGF-β-resistant hepatoma cells after expression of TGF-β receptor type II
    • Inagaki M, Moustakas A, Lin HY, Lodish HF and Carr BI (1993) Growth inhibition by transforming growth factor-β (TGF-β) is restored in TGF-β-resistant hepatoma cells after expression of TGF-β receptor type II. Proceedings of the National Academy of Sciences of the USA 90 5359-5363
    • (1993) Proceedings of the National Academy of Sciences of the USA , vol.90 , pp. 5359-5363
    • Inagaki, M.1    Moustakas, A.2    Lin, H.Y.3    Lodish, H.F.4    Carr, B.I.5
  • 51
    • 0028176086 scopus 로고
    • TGF-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site
    • Inagaki Y, Truter S and Ramirez F (1994) TGF-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site. Journal of Biological Chemistry 269 14828-14834
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 14828-14834
    • Inagaki, Y.1    Truter, S.2    Ramirez, F.3
  • 52
    • 0027440164 scopus 로고
    • Rapamycin-FKBP12 blocks proliferation induces differentiation and inhibits cdc2 kinase activity in a myogenic cell line
    • Jayaraman T and Marks AR (1993) Rapamycin-FKBP12 blocks proliferation induces differentiation and inhibits cdc2 kinase activity in a myogenic cell line. Journal of Biological Chemistry 268 25385-25388
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 25385-25388
    • Jayaraman, T.1    Marks, A.R.2
  • 54
    • 0028931238 scopus 로고
    • Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-β receptor
    • Kawabata M, Chytil A and Moses HL (1995a) Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-β receptor. Journal of Biological Chemistry 270 5625-5630
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 5625-5630
    • Kawabata, M.1    Chytil, A.2    Moses, H.L.3
  • 55
    • 0029610361 scopus 로고
    • Interaction of the transforming growth factor-β type I receptor with farnesyl-protein transferase-α
    • Kawabata M, Imamura T, Miyazono K, Engel ME and Moses HL (1995b) Interaction of the transforming growth factor-β type I receptor with farnesyl-protein transferase-α. Journal of Biological Chemistry 270 29628-29631
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 29628-29631
    • Kawabata, M.1    Imamura, T.2    Miyazono, K.3    Engel, M.E.4    Moses, H.L.5
  • 56
    • 0025920616 scopus 로고
    • Anti-Müllerian hormone Bruxelles: A nonsense mutation associated with the persistent Müllerian duct syndrome
    • Knebelmann B, Boussin L, Guerrier D et al (1991) Anti-Müllerian hormone Bruxelles: a nonsense mutation associated with the persistent Müllerian duct syndrome. Proceedings of the National Academy of Sciences of the USA 88 3767-3771
    • (1991) Proceedings of the National Academy of Sciences of the USA , vol.88 , pp. 3767-3771
    • Knebelmann, B.1    Boussin, L.2    Guerrier, D.3
  • 57
    • 0028142801 scopus 로고
    • Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH3T3 cells
    • Koenig BB, Cook JS, Wolsing DH et al (1994) Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH3T3 cells. Molecular and Cellular Biology 14 5961-5974
    • (1994) Molecular and Cellular Biology , vol.14 , pp. 5961-5974
    • Koenig, B.B.1    Cook, J.S.2    Wolsing, D.H.3
  • 59
    • 0025326725 scopus 로고
    • Growth inhibition by TGF-β1 linked to suppression of retinoblastoma protein phosphorylation
    • Laiho M, DeCaprio JA, Ludlow JW, Livingston DM and Massagué J (1990) Growth inhibition by TGF-β1 linked to suppression of retinoblastoma protein phosphorylation. Cell 62 175-185
    • (1990) Cell , vol.62 , pp. 175-185
    • Laiho, M.1    DeCaprio, J.A.2    Ludlow, J.W.3    Livingston, D.M.4    Massagué, J.5
  • 60
    • 0025773387 scopus 로고
    • Responsiveness to transforming growth factor-β restored by complementation between cells defective in TGF-β receptors I and II
    • Laiho M, Weis FMB, Boyd FT, Ignotz RA and Massagué J (1991) Responsiveness to transforming growth factor-β restored by complementation between cells defective in TGF-β receptors I and II. Journal of Biological Chemistry 266 9108-9112
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 9108-9112
    • Laiho, M.1    Weis, F.M.B.2    Boyd, F.T.3    Ignotz, R.A.4    Massagué, J.5
  • 61
    • 0025129867 scopus 로고
    • Concomitant loss of transforming growth factor-β receptor types I and II in cell mutants resistant to TGF-β
    • Laiho M, Weis FMB and Massagué J (1990) Concomitant loss of transforming growth factor-β receptor types I and II in cell mutants resistant to TGF-β. Journal of Biological Chemistry 265 18518-18524
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 18518-18524
    • Laiho, M.1    Weis, F.M.B.2    Massagué, J.3
  • 62
    • 0028907069 scopus 로고
    • Drosophila dpp signaling is mediated by the punt gene product: A dual ligand binding type II receptor of the TGF-β receptor family
    • Letsou A, Arora K, Wrana J et al (1995) Drosophila dpp signaling is mediated by the punt gene product: a dual ligand binding type II receptor of the TGF-β receptor family. Cell 80 899-908
    • (1995) Cell , vol.80 , pp. 899-908
    • Letsou, A.1    Arora, K.2    Wrana, J.3
  • 64
    • 0026537831 scopus 로고
    • Expression cloning of the TGF-β type II receptor a functional transmembrane serine/threonine kinase
    • Lin HY, Wang X-F, Ng-Eaton E, Weinberg R and Lodish H (1992) Expression cloning of the TGF-β type II receptor a functional transmembrane serine/threonine kinase. Cell 68 775-785
    • (1992) Cell , vol.68 , pp. 775-785
    • Lin, H.Y.1    Wang, X.-F.2    Ng-Eaton, E.3    Weinberg, R.4    Lodish, H.5
  • 65
    • 0029008597 scopus 로고
    • Human type II receptor for bone morphogenetic proteins (BMPs): Extension of the two-kinase receptor model to the BMPs
    • Liu F, Ventura F, Doody J and Massagué J (1995) Human type II receptor for bone morphogenetic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Molecular and Cellular Biology 15 3479-3486
    • (1995) Molecular and Cellular Biology , vol.15 , pp. 3479-3486
    • Liu, F.1    Ventura, F.2    Doody, J.3    Massagué, J.4
  • 66
    • 0025987832 scopus 로고
    • Structure and expression of the membrane proteoglycan betaglycan a component of the TGF-β receptor system
    • López-Casillas F, Cheifetz S, Doody J et al (1991) Structure and expression of the membrane proteoglycan betaglycan a component of the TGF-β receptor system. Cell 67 785-795
    • (1991) Cell , vol.67 , pp. 785-795
    • López-Casillas, F.1    Cheifetz, S.2    Doody, J.3
  • 67
    • 0027276765 scopus 로고
    • Betaglycan presents ligand to the TGF-β signaling receptor
    • López-Casillas F, Wrana JL and Massagué J (1993) Betaglycan presents ligand to the TGF-β signaling receptor. Cell 73 1435-1444
    • (1993) Cell , vol.73 , pp. 1435-1444
    • López-Casillas, F.1    Wrana, J.L.2    Massagué, J.3
  • 69
    • 0028171579 scopus 로고
    • Endoglin a TGF-β binding protein of endothelial cells is the gene for hereditary haemorrhagic telangiectasia type 1
    • McAllister KA, Grogg KM, Johnson DW et al (1994) Endoglin a TGF-β binding protein of endothelial cells is the gene for hereditary haemorrhagic telangiectasia type 1. Nature Genetics 8 345-351
    • (1994) Nature Genetics , vol.8 , pp. 345-351
    • McAllister, K.A.1    Grogg, K.M.2    Johnson, D.W.3
  • 71
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
    • Markowitz S, Wang J, Myeroff L et al (1995) Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 268 1336-1338
    • (1995) Science , vol.268 , pp. 1336-1338
    • Markowitz, S.1    Wang, J.2    Myeroff, L.3
  • 72
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • Massagué J (1990) The transforming growth factor-β family. Annual Review of Cell Biology 6 597-641
    • (1990) Annual Review of Cell Biology , vol.6 , pp. 597-641
    • Massagué, J.1
  • 73
    • 0030604542 scopus 로고    scopus 로고
    • TGFβ signaling: Receptors, transducers and Mad proteins
    • Massagué J (1996) TGFβ signaling: receptors, transducers and Mad proteins. Cell 85 947-950
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 74
    • 0028273882 scopus 로고
    • Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22
    • Mathew S, Murty VVV, Cheifetz S et al (1994) Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22. Genomics 20 114-115
    • (1994) Genomics , vol.20 , pp. 114-115
    • Mathew, S.1    Murty, V.V.V.2    Cheifetz, S.3
  • 75
    • 0025905181 scopus 로고
    • Expression cloning of an activin receptor, a predicted transmembrane kinase
    • Mathews LS and Vale WW (1991) Expression cloning of an activin receptor, a predicted transmembrane kinase. Cell 65 973-982
    • (1991) Cell , vol.65 , pp. 973-982
    • Mathews, L.S.1    Vale, W.W.2
  • 76
    • 0027160743 scopus 로고
    • Characterization of type II activin receptors: Binding, processing and phosphorylation
    • Mathews LS and Vale WW (1993) Characterization of type II activin receptors: binding, processing and phosphorylation. Journal of Biological Chemistry 268 19013-19018
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 19013-19018
    • Mathews, L.S.1    Vale, W.W.2
  • 77
    • 0026529503 scopus 로고
    • Cloning of a second type of activin receptor and functional characterization in Xenopus embryos
    • Mathews LS, Vale WW and Kintner CR (1992) Cloning of a second type of activin receptor and functional characterization in Xenopus embryos. Science 255 1702-1705
    • (1992) Science , vol.255 , pp. 1702-1705
    • Mathews, L.S.1    Vale, W.W.2    Kintner, C.R.3
  • 78
    • 0028929864 scopus 로고
    • Different phenotypes for mice deficient in either activins or the activin type II receptor
    • Matzuk MM, Kumar TR and Bradley A (1995) Different phenotypes for mice deficient in either activins or the activin type II receptor. Nature 374 356-359
    • (1995) Nature , vol.374 , pp. 356-359
    • Matzuk, M.M.1    Kumar, T.R.2    Bradley, A.3
  • 79
    • 0028603343 scopus 로고
    • TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
    • Mienttinen PJ, Ebner R, Lopez AR and Derynck R (1994) TGF-β induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. Journal of Cell Biology 127 2021-2036
    • (1994) Journal of Cell Biology , vol.127 , pp. 2021-2036
    • Mienttinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 80
    • 0027466618 scopus 로고
    • Transforming growth factor-β: Latent forms, binding proteins and receptors
    • Miyazono K, Ichijo H and Heldin C-H (1993) Transforming growth factor-β: latent forms, binding proteins and receptors. Growth Factors 8 11-22
    • (1993) Growth Factors , vol.8 , pp. 11-22
    • Miyazono, K.1    Ichijo, H.2    Heldin, C.-H.3
  • 81
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO (1995) Principles of CDK regulation. Nature 374 131-134
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 82
    • 0025104027 scopus 로고
    • TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
    • Moses HL, Yang EY and Pietenpol JA (1990) TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63 245-247
    • (1990) Cell , vol.63 , pp. 245-247
    • Moses, H.L.1    Yang, E.Y.2    Pietenpol, J.A.3
  • 84
    • 0025117393 scopus 로고
    • Activin-binding protein from rat ovary is follistatin
    • Nakamura T, Takio K, Eto Y et al (1990) Activin-binding protein from rat ovary is follistatin. Science 247 836-838
    • (1990) Science , vol.247 , pp. 836-838
    • Nakamura, T.1    Takio, K.2    Eto, Y.3
  • 85
    • 0027953772 scopus 로고
    • Receptor ser/thr kinases implicated in the control of Drosophila body pattern by decapentaplegic
    • Nellen D, Affolter M and Basler K (1994) Receptor ser/thr kinases implicated in the control of Drosophila body pattern by decapentaplegic. Cell 78 225-237
    • (1994) Cell , vol.78 , pp. 225-237
    • Nellen, D.1    Affolter, M.2    Basler, K.3
  • 86
    • 0029153741 scopus 로고
    • Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors
    • Nohno T, Ishikawa T, Saito T et al (1995) Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors. Journal of Biological Chemistry 270 22522-22526
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 22522-22526
    • Nohno, T.1    Ishikawa, T.2    Saito, T.3
  • 87
    • 0023193194 scopus 로고
    • Latent transforming growth factor-β in serum: A specific complex with α2-macroglobulin
    • O'Connor-McCourt MD and Wakefield LM (1987) Latent transforming growth factor-β in serum: a specific complex with α2-macroglobulin. Journal of Biological Chemistry 262 14090-14099
    • (1987) Journal of Biological Chemistry , vol.262 , pp. 14090-14099
    • O'Connor-McCourt, M.D.1    Wakefield, L.M.2
  • 88
    • 0028062958 scopus 로고
    • Distinct roles of the intracellular domains of transforming growth factor-β type I and type II receptors in signal transduction
    • Okadome T, Yamashita H, Franzén P et al (1994) Distinct roles of the intracellular domains of transforming growth factor-β type I and type II receptors in signal transduction. Journal of Biological Chemistry 269 30753-30756
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 30753-30756
    • Okadome, T.1    Yamashita, H.2    Franzén, P.3
  • 89
    • 0028987265 scopus 로고
    • Mutations in the p16INK4/MTS1/CDKN2, p15INK4B/MTS2 and p18 genes in primary and metastatic lung cancer
    • Okamoto A, Hussain SP, Hagiwara K et al (1995) Mutations in the p16INK4/MTS1/CDKN2, p15INK4B/MTS2 and p18 genes in primary and metastatic lung cancer. Cancer Research 55 1448-1451
    • (1995) Cancer Research , vol.55 , pp. 1448-1451
    • Okamoto, A.1    Hussain, S.P.2    Hagiwara, K.3
  • 91
    • 0028556486 scopus 로고
    • Genetic changes in the transforming growth factor β type II receptor gene in human gastric cancer cells: Correlation with sensitivity to growth inhibition by TGF-β
    • Park K, Kin S-J, Bang YJ et al (1994) Genetic changes in the transforming growth factor β type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-β. Proceedings of the National Academy of Sciences of the USA 91 8772-8776
    • (1994) Proceedings of the National Academy of Sciences of the USA , vol.91 , pp. 8772-8776
    • Park, K.1    Kin, S.-J.2    Bang, Y.J.3
  • 92
    • 0028141433 scopus 로고
    • Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor
    • Penton A, Chen Y, Staehling-Hampton K et al (1994) Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell 78 239-250
    • (1994) Cell , vol.78 , pp. 239-250
    • Penton, A.1    Chen, Y.2    Staehling-Hampton, K.3
  • 93
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arest in response to TGF-β
    • Reynisdóttir I, Polyak K, Iavarone A and Massagué J (1995) Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arest in response to TGF-β. Genes and Development 9 1831-1845
    • (1995) Genes and Development , vol.9 , pp. 1831-1845
    • Reynisdóttir, I.1    Polyak, K.2    Iavarone, A.3    Massagué, J.4
  • 94
    • 0000116653 scopus 로고
    • The transforming growth factor-betas
    • Sporn MB and Roberts AB (eds). Springer-Verlag, Heidelberg
    • Roberts AB and Sporn MB (1990) The transforming growth factor-betas, In: Sporn MB and Roberts AB (eds). Peptide growth factors and their receptors, pp 419-472, Springer-Verlag, Heidelberg
    • (1990) Peptide Growth Factors and Their Receptors , pp. 419-472
    • Roberts, A.B.1    Sporn, M.B.2
  • 96
    • 0028923022 scopus 로고
    • An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo
    • Ruberte E, Marty T, Nellen D, Affolter M and Basler K (1995) An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell 80 889-897
    • (1995) Cell , vol.80 , pp. 889-897
    • Ruberte, E.1    Marty, T.2    Nellen, D.3    Affolter, M.4    Basler, K.5
  • 97
    • 0026625939 scopus 로고
    • Immunophilin-sensitive protein phosphatase action in cell signaling pathways
    • Schreiber S (1992) Immunophilin-sensitive protein phosphatase action in cell signaling pathways. Cell 70 385-368
    • (1992) Cell , vol.70 , pp. 385-1368
    • Schreiber, S.1
  • 98
    • 0023948067 scopus 로고
    • The high molecular weight receptor to transforming growth factor-β contains glycosaminoglycan chains
    • Segarini PR and Seyedin SM (1988) The high molecular weight receptor to transforming growth factor-β contains glycosaminoglycan chains. Journal of Biological Chemistry 263 8366-8370
    • (1988) Journal of Biological Chemistry , vol.263 , pp. 8366-8370
    • Segarini, P.R.1    Seyedin, S.M.2
  • 99
    • 0028940853 scopus 로고
    • Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
    • Sekelsky JJ, Newfeld SJ, Raftery LA, Chartoff EH and Gelbart WM (1995) Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139 1347-1358
    • (1995) Genetics , vol.139 , pp. 1347-1358
    • Sekelsky, J.J.1    Newfeld, S.J.2    Raftery, L.A.3    Chartoff, E.H.4    Gelbart, W.M.5
  • 100
    • 0028171292 scopus 로고
    • 1 phase progression: Cycling on cue
    • 1 phase progression: cycling on cue. Cell 79 551-555
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 102
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB et al (1992) Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359 693-699
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3
  • 103
    • 0025354027 scopus 로고
    • Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-β
    • Sieweke MH, Thompson NL, Sporn MB and Bissell MJ (1990) Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-β. Science 248 1656-1660
    • (1990) Science , vol.248 , pp. 1656-1660
    • Sieweke, M.H.1    Thompson, N.L.2    Sporn, M.B.3    Bissell, M.J.4
  • 106
    • 0027328191 scopus 로고
    • Activin receptor-like kinases: A novel subclass of cell-surface receptors with predicted serine/threonine kinase activity
    • ten Dijke P, Ichijo H, Franzén P et al (1993) Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. Oncogene 8 2879-2887
    • (1993) Oncogene , vol.8 , pp. 2879-2887
    • Ten Dijke, P.1    Ichijo, H.2    Franzén, P.3
  • 107
    • 0028295762 scopus 로고
    • Characterization of type I receptors for transforming growth factor-β and activin
    • ten Dijke P, Yamashita H, Ichijo H et al (1994a) Characterization of type I receptors for transforming growth factor-β and activin. Science 264 101-104
    • (1994) Science , vol.264 , pp. 101-104
    • Ten Dijke, P.1    Yamashita, H.2    Ichijo, H.3
  • 108
    • 0028332818 scopus 로고
    • Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4
    • ten Dijke P, Yamashita H, Sampath TK et al (1994b) Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. Journal of Biological Chemistry 269 16985-16988
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 16985-16988
    • Ten Dijke, P.1    Yamashita, H.2    Sampath, T.K.3
  • 109
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich A and Schlessinger J (1990) Signal transduction by receptors with tyrosine kinase activity. Cell 61 203-212
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 110
    • 0000775642 scopus 로고
    • The inhibin/activin family of hormones and growth factors
    • Sporn MB and Roberts AB (eds). Springer-Verlag, Heidelberg
    • Vale W, Hsueh A, Rivier C and Yu J (1990) The inhibin/activin family of hormones and growth factors, In: Sporn MB and Roberts AB (eds). Peptide growth factors and their receptors, pp 211-248.95, Springer-Verlag, Heidelberg
    • (1990) Peptide Growth Factors and Their Receptors , pp. 211-248
    • Vale, W.1    Hsueh, A.2    Rivier, C.3    Yu, J.4
  • 111
    • 0028171082 scopus 로고
    • Reconstitution and transphos-phorylation of TGF-β receptor complexes
    • Ventura F, Doody J, Liu F, Wrana JL and Massagué J (1994) Reconstitution and transphos-phorylation of TGF-β receptor complexes. EMBO Journal 13 5581-5589
    • (1994) EMBO Journal , vol.13 , pp. 5581-5589
    • Ventura, F.1    Doody, J.2    Liu, F.3    Wrana, J.L.4    Massagué, J.5
  • 112
    • 0029941824 scopus 로고    scopus 로고
    • Transforming growth factor-β receptor type I interacts with farnesyl transferase-α in mammalian cells
    • Ventura F, Liu F, Doody J and Massagué J (1996) Transforming growth factor-β receptor type I interacts with farnesyl transferase-α in mammalian cells. journal of Biological Chemistry 271 13931-13934
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 13931-13934
    • Ventura, F.1    Liu, F.2    Doody, J.3    Massagué, J.4
  • 114
    • 0026559398 scopus 로고
    • Transforming growth factor-β (TGF-β) in inflammation: A cause and a cure
    • Wahl SM (1992) Transforming growth factor-β (TGF-β) in inflammation: a cause and a cure. Journal of Clinical Immunology 12 61-74
    • (1992) Journal of Clinical Immunology , vol.12 , pp. 61-74
    • Wahl, S.M.1
  • 115
    • 0028108801 scopus 로고
    • Specific interaction of type I receptors of the TGF-β family with the immunophilin FKBP-12
    • Wang T, Donahoe PK and Zervos AS (1994) Specific interaction of type I receptors of the TGF-β family with the immunophilin FKBP-12. Science 265 674-676
    • (1994) Science , vol.265 , pp. 674-676
    • Wang, T.1    Donahoe, P.K.2    Zervos, A.S.3
  • 116
    • 0029670049 scopus 로고    scopus 로고
    • The p21RAS farnesyltransferase α subunit in TGF-β and activin signaling
    • Wang T, Danielson PD, Li B, Shah PC, Kim SD and Donohoe PK (1996) The p21RAS farnesyltransferase α subunit in TGF-β and activin signaling. Science 271 1120-1122
    • (1996) Science , vol.271 , pp. 1120-1122
    • Wang, T.1    Danielson, P.D.2    Li, B.3    Shah, P.C.4    Kim, S.D.5    Donohoe, P.K.6
  • 117
    • 0025989562 scopus 로고
    • Expression cloning and characterization of the TGF-β type III receptor
    • Wang X-F, Lin HY, Ng-Eaton E et al (1991) Expression cloning and characterization of the TGF-β type III receptor. Cell 67 797-805
    • (1991) Cell , vol.67 , pp. 797-805
    • Wang, X.-F.1    Lin, H.Y.2    Ng-Eaton, E.3
  • 118
    • 0030030373 scopus 로고    scopus 로고
    • Complementation between kinase-defective and activation-defective TGF-β receptors reveals a novel form of receptor cooperativity essential for signaling
    • Weis-Garcia F and Massagué J (1996) Complementation between kinase-defective and activation-defective TGF-β receptors reveals a novel form of receptor cooperativity essential for signaling. EMBO Journal 15 276-289
    • (1996) EMBO Journal , vol.15 , pp. 276-289
    • Weis-Garcia, F.1    Massagué, J.2
  • 119
    • 0027367937 scopus 로고
    • Signalling activity of TGF-β type II receptors lacking specific domains in the cytoplasmic region
    • Wieser R, Attisano L, Wrana JL and Massagué J (1993) Signalling activity of TGF-β type II receptors lacking specific domains in the cytoplasmic region. Molecular and Cellular Biology 13 7239-7247
    • (1993) Molecular and Cellular Biology , vol.13 , pp. 7239-7247
    • Wieser, R.1    Attisano, L.2    Wrana, J.L.3    Massagué, J.4
  • 120
    • 0029022221 scopus 로고
    • GS domain mutations that constitutively activate TßR-I, the downstream signaling component in the TGF-β receptor complex
    • Wieser R, Wrana JL and Massagué J (1995) GS domain mutations that constitutively activate TßR-I, the downstream signaling component in the TGF-β receptor complex. EMBO Journal 14 2199-2208
    • (1995) EMBO Journal , vol.14 , pp. 2199-2208
    • Wieser, R.1    Wrana, J.L.2    Massagué, J.3
  • 121
    • 0024521844 scopus 로고
    • Signal transduction by the platelet-derived growth factor receptor
    • Williams LT (1989) Signal transduction by the platelet-derived growth factor receptor. Science 243 1564-1570
    • (1989) Science , vol.243 , pp. 1564-1570
    • Williams, L.T.1
  • 122
    • 0028978274 scopus 로고
    • INK4A-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in human melanoma
    • INK4A-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in human melanoma. Science 269 1281-1284
    • (1995) Science , vol.269 , pp. 1281-1284
    • Wölfel, T.1    Hauer, M.2    Schneider, J.3
  • 123
    • 0026496172 scopus 로고
    • TGF-β signals through a heteromeric protein kinase receptor complex
    • Wrana JL, Attisano L, Carcamo J et al (1992) TGF-β signals through a heteromeric protein kinase receptor complex. Cell 71 1003-1014
    • (1992) Cell , vol.71 , pp. 1003-1014
    • Wrana, J.L.1    Attisano, L.2    Carcamo, J.3
  • 125
    • 0028014395 scopus 로고
    • Two distinct transmembrane serine/threonine kinases from Drosophila form an activin receptor complex
    • Wrana JL, Tran H, Attisano L et al (1994b) Two distinct transmembrane serine/threonine kinases from Drosophila form an activin receptor complex. Molecular and Cellular Biology 14 944-950
    • (1994) Molecular and Cellular Biology , vol.14 , pp. 944-950
    • Wrana, J.L.1    Tran, H.2    Attisano, L.3
  • 126
    • 0028218186 scopus 로고
    • The Drosophila saxophone gene: A serine-threonine kinase receptor of the TGF-β superfamily
    • Xie T, Finelli AL and Padgett RW (1994) The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-β superfamily. Science 263 1756-1759
    • (1994) Science , vol.263 , pp. 1756-1759
    • Xie, T.1    Finelli, A.L.2    Padgett, R.W.3
  • 127
    • 0025353729 scopus 로고
    • Negative regulation of transforming growth factor-β by the proteoglycan decorin
    • Yamaguchi Y, Mann DM and Ruoslahti E (1990) Negative regulation of transforming growth factor-β by the proteoglycan decorin. Nature 346 281-283
    • (1990) Nature , vol.346 , pp. 281-283
    • Yamaguchi, Y.1    Mann, D.M.2    Ruoslahti, E.3
  • 128
    • 0027930903 scopus 로고
    • Formation of heterooligomeric complexes of type I and type II receptors for transforming growth factor-β
    • Yamashita H, ten Dijke P, Franzén P, Miyazono K and Heldin C-H (1994) Formation of heterooligomeric complexes of type I and type II receptors for transforming growth factor-β. Journal of Biological Chemistry 269 20172-20178
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 20172-20178
    • Yamashita, H.1    Ten Dijke, P.2    Franzén, P.3    Miyazono, K.4    Heldin, C.-H.5
  • 129
    • 0029003377 scopus 로고
    • Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects
    • Yamashita H, ten Dijke P, Huylebroeck D et al (1995) Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects. Journal of Cell Biology 130 217-226
    • (1995) Journal of Cell Biology , vol.130 , pp. 217-226
    • Yamashita, H.1    Ten Dijke, P.2    Huylebroeck, D.3


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