-
1
-
-
0034701238
-
The origins of Alzheimer disease: A is for amyloid
-
Selkoe D.J. The origins of Alzheimer disease: A is for amyloid JAMA. 283 2000 1615-1617
-
(2000)
JAMA
, vol.283
, pp. 1615-1617
-
-
Selkoe, D.J.1
-
2
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J. Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science. 297 2002 353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
3
-
-
0001320564
-
Molecular pathology of Alzheimer's disease and related disorders. Cerebral cortex: Neurodegenerative and age-related changes in structure and function of cerebral cortex
-
New York: Kluwer Academic/Plenum
-
Ginsberg S.D. Schmidt M.L. Crino P.B. Eberwine J.H. Lee V.M.-Y. Trojanowski J.Q. Molecular pathology of Alzheimer's disease and related disorders. Cerebral cortex: neurodegenerative and age-related changes in structure and function of cerebral cortex 1999 Kluwer Academic/Plenum New York 603-654
-
(1999)
, pp. 603-654
-
-
Ginsberg, S.D.1
Schmidt, M.L.2
Crino, P.B.3
Eberwine, J.H.4
Lee, V.M.-Y.5
Trojanowski, J.Q.6
-
4
-
-
0035902875
-
Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain
-
Klunk W.E. Wang Y. Huang G.-F. Debnath M.L. Holt D.P. Mathis C.A. Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain Life Sci. 69 2001 1471-1484
-
(2001)
Life Sci.
, vol.69
, pp. 1471-1484
-
-
Klunk, W.E.1
Wang, Y.2
Huang, G.-F.3
Debnath, M.L.4
Holt, D.P.5
Mathis, C.A.6
-
5
-
-
0035893245
-
Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for β-amyloid plaques in Alzheimer's disease
-
Agdeppa E.D. Kepe V. Liu J. et al. Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for β-amyloid plaques in Alzheimer's disease J. Neurosci. 21 2001 RC189
-
(2001)
J. Neurosci.
, vol.21
-
-
Agdeppa, E.D.1
Kepe, V.2
Liu, J.3
-
7
-
-
15844405638
-
Technetium complexes for the quantitation of brain amyloid
-
Han H. Cho C.-G. Lansbury Jr. P.T. Technetium complexes for the quantitation of brain amyloid J. Am. Chem. Soc. 118 1996 4506-4507
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 4506-4507
-
-
Han, H.1
Cho, C.-G.2
Lansbury Jr., P.T.3
-
8
-
-
0033614955
-
Synthesis and amyloid binding properties of rhenium complexes: Preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain
-
Zhen W. Han H. Anguiano M. Lemere C.A. Cho C.G. Lansbury Jr. P.T. Synthesis and amyloid binding properties of rhenium complexes: preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain J. Med. Chem. 42 1999 2805-2815
-
(1999)
J. Med. Chem.
, vol.42
, pp. 2805-2815
-
-
Zhen, W.1
Han, H.2
Anguiano, M.3
Lemere, C.A.4
Cho, C.G.5
Lansbury Jr., P.T.6
-
9
-
-
0029083059
-
Chrysamine-G binding to Alzheimer's and control brain: Autopsy study of a new amyloid probe
-
Klunk W.E. Debnath M.L. Pettegrew J.W. Chrysamine-G binding to Alzheimer's and control brain: autopsy study of a new amyloid probe Neurobiol. Aging. 16 1995 541-548
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 541-548
-
-
Klunk, W.E.1
Debnath, M.L.2
Pettegrew, J.W.3
-
10
-
-
0035821603
-
Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates
-
Zhuang Z.P. Kung M.-P. Hou C. et al. Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates J. Med. Chem. 44 2001 1905-1914
-
(2001)
J. Med. Chem.
, vol.44
, pp. 1905-1914
-
-
Zhuang, Z.P.1
Kung, M.-P.2
Hou, C.3
-
11
-
-
0037059914
-
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain
-
Mathis C.A. Bacskai B.J. Kajdasz S.T.B.M.C. et al. A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. Bioorg Med. Chem. Lett. 12 2002 295-298
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 295-298
-
-
Mathis, C.A.1
Bacskai, B.J.2
Kajdasz, S.T.B.M.C.3
-
12
-
-
0344168212
-
Binding of a benzothiazole amyloid-imaging PET tracer to human brain is dominated by specific interaction with the amyloid component in vitro and in vivo
-
32nd Annual Meeting of Society for Neuroscience, Orlando, FL, Program Number: 228.229
-
Klunk, W.; Mathis, C.; Wang, Y.; et al. Binding of a benzothiazole amyloid-imaging PET tracer to human brain is dominated by specific interaction with the amyloid component in vitro and in vivo. 32nd Annual Meeting of Society for Neuroscience, Orlando, FL, Program Number: 228.229; 2002.
-
(2002)
-
-
Klunk, W.1
Mathis, C.2
Wang, Y.3
-
13
-
-
84903202261
-
Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease: Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer disease
-
Shoghi-Jadid K. Small G.W. Agdeppa E.D. et al. Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease: binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer disease Am. J. Geriatr. Psychiatry. 10 2002 24-35
-
(2002)
Am. J. Geriatr. Psychiatry
, vol.10
, pp. 24-35
-
-
Shoghi-Jadid, K.1
Small, G.W.2
Agdeppa, E.D.3
-
14
-
-
0036173189
-
Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical
-
Lee H.J. Zhang Y. Zhu C. Duff K. Pardridge W.M. Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical J. Cereb. Blood Flow Metab. 22 2002 223-231
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 223-231
-
-
Lee, H.J.1
Zhang, Y.2
Zhu, C.3
Duff, K.4
Pardridge, W.M.5
-
15
-
-
0036672696
-
Synthesis and evaluation of 2-(3'-Iodo-4'-aminophenyl)-6- hydroxybenzothiazole for in vivo quantitation of amyloid deposits in Alzheimer's disease
-
Wang Y. Klunk W.E. Huang G.-F. Debnath M.L. Holt D.P. Mathis C.A. Synthesis and evaluation of 2-(3'-Iodo-4'-aminophenyl)-6- hydroxybenzothiazole for in vivo quantitation of amyloid deposits in Alzheimer's disease J. Mol. Neurosci. 19 2002 11-16
-
(2002)
J. Mol. Neurosci.
, vol.19
, pp. 11-16
-
-
Wang, Y.1
Klunk, W.E.2
Huang, G.-F.3
Debnath, M.L.4
Holt, D.P.5
Mathis, C.A.6
-
16
-
-
0035159024
-
IBOX(2-(4'-dimethylaminophenyl)-6-iodobenzoxazole): A ligand for imaging amyloid plaques in the brain
-
Zhuang Z.P. Kung M.-P. Hou C. et al. IBOX(2-(4'-dimethylaminophenyl)-6- iodobenzoxazole): a ligand for imaging amyloid plaques in the brain Nucl. Med. Biol. 28 2001 887-894
-
(2001)
Nucl. Med. Biol.
, vol.28
, pp. 887-894
-
-
Zhuang, Z.P.1
Kung, M.-P.2
Hou, C.3
-
17
-
-
0036668810
-
Benzofuran derivatives as Aβ-aggregate-specific imaging agents for Alzheimer's disease
-
Ono M. Kung M.-P. Hou C. Kung H.F. Benzofuran derivatives as Aβ-aggregate-specific imaging agents for Alzheimer's disease Nucl. Med. Biol. 29 2002 633-642
-
(2002)
Nucl. Med. Biol.
, vol.29
, pp. 633-642
-
-
Ono, M.1
Kung, M.-P.2
Hou, C.3
Kung, H.F.4
-
19
-
-
0142011533
-
Dimethylamino-fluorenes: Ligands for detecting β-amyloid plaques in the brain
-
Lee C.-W. Kung M.-P. Hou C. Kung H.F. Dimethylamino-fluorenes: ligands for detecting β-amyloid plaques in the brain Nucl. Med. Biol. 30 2003 573-580
-
(2003)
Nucl. Med. Biol.
, vol.30
, pp. 573-580
-
-
Lee, C.-W.1
Kung, M.-P.2
Hou, C.3
Kung, H.F.4
-
20
-
-
0037448350
-
Structure-activity relationship of imidazo[1, 2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain
-
Zhuang Z.P. Kung M.-P. Wilson A. et al. Structure-activity relationship of imidazo[1, 2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain J. Med. Chem. 46 2003 237-243
-
(2003)
J. Med. Chem.
, vol.46
, pp. 237-243
-
-
Zhuang, Z.P.1
Kung, M.-P.2
Wilson, A.3
-
21
-
-
0345030725
-
Synthesis and characterization of 125I/123I IMPY as an abeta-plaque imaging agent
-
Kung H.F. Synthesis and characterization of 125I/123I IMPY as an abeta-plaque imaging agent J. Nucl. Med. 43 2002 166P
-
(2002)
J. Nucl. Med.
, vol.43
-
-
Kung, H.F.1
-
23
-
-
0028076051
-
Development of small molecule probes for the beta-amyloid protein of Alzheimer's disease
-
Klunk W.E. Debnath M.L. Pettegrew J.W. Development of small molecule probes for the beta-amyloid protein of Alzheimer's disease Neurobiol. Aging. 15 1994 691-698
-
(1994)
Neurobiol. Aging
, vol.15
, pp. 691-698
-
-
Klunk, W.E.1
Debnath, M.L.2
Pettegrew, J.W.3
-
24
-
-
0019061918
-
LIGAND: A versatile computerized approach for characterization of ligand-binding systems
-
Munson P.J. Rodbard D. LIGAND: a versatile computerized approach for characterization of ligand-binding systems Anal. Biochem. 107 1980 220-239
-
(1980)
Anal. Biochem.
, vol.107
, pp. 220-239
-
-
Munson, P.J.1
Rodbard, D.2
-
25
-
-
0032417251
-
Transgenic mice expressing Alzheimer amyloid precursor proteins
-
Hsiao K. Transgenic mice expressing Alzheimer amyloid precursor proteins Exp. Gerontol. 33 1998 883-889
-
(1998)
Exp. Gerontol.
, vol.33
, pp. 883-889
-
-
Hsiao, K.1
-
26
-
-
12444341957
-
Detection of amyloid plaques by radioligands for Aβ40 and Aβ42: Potential imaging agents in Alzheimer's patients
-
Kung M. Skovronsky D. Hou C. et al. Detection of amyloid plaques by radioligands for Aβ40 and Aβ42: potential imaging agents in Alzheimer's patients J. Mol. Neurosci. 20 2002 33-41
-
(2002)
J. Mol. Neurosci.
, vol.20
, pp. 33-41
-
-
Kung, M.1
Skovronsky, D.2
Hou, C.3
-
27
-
-
0032211830
-
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe D.J. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease Trends Cell Biol. 8 1998 447-453
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
28
-
-
0030660554
-
Neuropathological diagnosis of Alzheimer's disease: A perspective from longitudinal clinicopathological studies
-
Dickson D.W. Neuropathological diagnosis of Alzheimer's disease: a perspective from longitudinal clinicopathological studies Neurobiol. Aging. 18 1997 S21-S26
-
(1997)
Neurobiol. Aging.
, vol.18
-
-
Dickson, D.W.1
-
29
-
-
0142075238
-
11C-Labeled stilbene derivatives as Aβ-aggregate-specific PET imaging agents for Alzheimer's disease
-
11C-Labeled stilbene derivatives as Aβ-aggregate-specific PET imaging agents for Alzheimer's disease Nucl. Med. Biol. 30 2003 561-571
-
(2003)
Nucl. Med. Biol.
, vol.30
, pp. 561-571
-
-
Ono, M.1
Wilson, A.2
Nobrega, J.3
|