Detection of amyloid plaques by radioligands for aβ40 and aβ42: Potential imaging agents in Alzheimer's patients

Journal of Molecular Neuroscience

Volumn 20, Issue 1, 2003, Pages 15-23

  Kung, Mei Ping ^a   Skovronsky, Daniel M ^a   Hou, Catherine ^a   Zhuang, Zhi Ping ^a   Gur, Tamar L ^a   Zhang, Bin ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a   Kung, Hank F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

A fibrils; Alzheimer's disease; Blood brain barrier; Imaging; Radioligand; Senile plaques

Indexed keywords

1 IODO 2,5 BIS(3 HYDROXYCARBONYL 4 METHOXY)STYRYLBENZENE I 125; 2 (4' DIMETHYLAMINOPHENYL) 6 IODOBENZOTHIAZOLE I 125; AMYLOID BETA PROTEIN; ISOPROTEIN; RADIOLIGAND; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; BRAIN REGION; CONTROLLED STUDY; FIBER; IMAGING; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; SENILE PLAQUE; VASCULAR AMYLOIDOSIS; WHITE MATTER;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ARTIFACTS; BINDING, COMPETITIVE; BLOOD-BRAIN BARRIER; BRAIN; HUMANS; IMMUNOHISTOCHEMISTRY; IODINE RADIOISOTOPES; MICE; MICE, TRANSGENIC; NERVE FIBERS, MYELINATED; PEPTIDE FRAGMENTS; RADIONUCLIDE IMAGING; REPRODUCIBILITY OF RESULTS; SENILE PLAQUES; STYRENES; THIAZOLES;

ANIMALIA;

EID: 12444341957     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:20:1:15     Document Type: Article

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