HIV/host interactions: New lessons from the Red Queen's country

AIDS

Volumn 16, Issue SUPPL. 4, 2002, Pages

  Ameisen, Jean Claude ^a,b   Lelièvre, Jean Daniel ^a   Pleskoff, Olivier ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSERM   (France)

Author keywords

Apoptosis; CD4; CD8; Coreceptors; Defensins; Genetic polymorphism; HLA; Immune response; RNA interference

Indexed keywords

ALPHA DEFENSIN; ANTIVIRUS AGENT; BETA DEFENSIN; CD4 ANTIGEN; CELL PROTEIN; CHAPERONE; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DEFENSIN; DNA; EPITOPE; FAS LIGAND; GAG PROTEIN; HLA ANTIGEN CLASS 1; HLA B ANTIGEN; HLA B27 ANTIGEN; HLA B35 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN HP68; RANTES; RIBONUCLEASE; RNA; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VPR PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ALLELE; ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; APOPTOSIS; B LYMPHOCYTE; CELL DEATH; CELL SURVIVAL; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DISEASE COURSE; GENETIC POLYMORPHISM; GENETIC SELECTION; GENETIC VARIABILITY; GENOTYPE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOST CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNE SYSTEM; MOLECULAR EVOLUTION; NATURAL KILLER CELL; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; REVIEW; RNA DEGRADATION; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE; TRANSPOSON; VERTICAL TRANSMISSION; VIRUS ASSEMBLY; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS IMMUNITY; VIRUS INACTIVATION; VIRUS MUTANT; VIRUS MUTATION; VIRUS RECOMBINATION; VIRUS REPLICATION; VIRUS TRANSMISSION;

EID: 0344838619     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200216004-00004     Document Type: Review

References (99)

1. vanValen, L. A new evolutionary law. Evol Theory 1973, I:1-30.
2. Weiss, RA. Virulence and pathogenesis. Trends Microbiol 2002, 10:314-317.
3. Broussard SR, Staprans SI, White R, et al. Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease. J Virol 2001, 75:2262-2275.
4. Jung A, Maier R, Vartanian JP, Bocharov G, et al. Multiply infected spleen cells in HIV patients. Nature 2002, 418:144.
5. Garnett GP, Bartley L, Grassly NC, Anderson RM. Antiretroviral therapy to treat and prevent HIV/AIDS in resource-poor settings. Nat Med 2002, 8:651-654.
6. Gaschen B, Taylor J, Yusim K, et al. Diversity considerations in HIV-1 vaccine selection. Science 2002, 296:2354-2360.
7. McMichael AJ, Rowland-Jones SL. Cellular immune responses to HIV. Nature 2001, 410:980-987.
8. Migueles, SA, Sabbaghian MS, Shupert WL et al. HLA B*5701 is highly associated with restriction of virus replication in a sub-group of HIV-infected long term nonprogressors. Proc Nat Acad Sci USA 2000, 97:2709-2714.
9. Kelleher AD, Long C, Holmes EC, et al. Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses. J Exp Med 2001, 193:375-386.
10. Gao X, Nelson GW, Karacki P, et al. Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS. N Engl J Med 2001, 344:1668-1675.
11. An P, Nelson GW, Wang L, et al. Modulating influence on HIV/AIDS by interacting RANTES gene variants. Proc Natl Acad Sci USA 2002, 99:10002-10007.
12. Bamshad MJ, Mummidi S, Gonzalez E, et al. A strong signature of balancing selection in the 5′ cis-regulatory region of CCR5. Proc Natl Acad Sci USA 2002, 99:10539-10544.
13. Ramaley PA, French N, Kaleebu P, et al. HIV in Africa (Communication arising): chemokine-receptor genes and AIDS risk. Nature 2002, 417:140.
14. Martin MP, Gao X, Lee JH, et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat Genet 2002, 31:429-434.
15. Hoelscher M, Kim B, Maboko U et al. The UNAIDS Network for HIV Isolation and Characterization. High proportion of unrelated HIV-1 intersubtype recombinants in the Mbeya region of southwest Tanzania. AIDS 2001, 15:1461-1470.
16. Sala M, Wain-Hobson S. Are RNA viruses adapting or merely changing? J Mol Evol 2000, 51:12-20.
17. Weiss RA. Gulliver's travels in HIVland. Nature 2001, 410:963-967.
18. O'Connor DH, Allen TM, Vogel TU, et al. Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection. Nat Med 2002, 8:493-499.
19. Goulder PJ, Brander C, Tang Y, et al. Evolution and transmission of stable CTL escape mutations in HIV infection. Nature 2001, 412:334-338.
20. Stoddart CA, Liegler TJ, Mammano F, et al. Impaired replication of protease inhibitor-resistant HIV-1 in human thymus. Nat Med 2001, 7:712-718.
21. Deeks SG, Hoh R, Grant RM, et al. CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy. J Infect Dis 2002, 185:315-323.
22. McMichael A, Klenerman P. HIV/AIDS. HLA leaves its foot-prints on HIV. Science. 2002, 296:1410-1411.
23. Moore CB, John M, James IR, et al. Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level. Science 2002, 296:1439-1443.
24. de Groot NG, Otting N, Doxiadis GG et al. Evidence for an ancient selective sweep in the MHC class I gene repertoire of chimpanzees. Proc Natl Acad Sci USA 1974, 71:4042-4046.
25. Meng G, Wei X, Wu X, et al. Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells. Nat Med 2002, 8:150-156.
26. Bomsel M, David V. Mucosal gatekeepers: selecting HIV viruses for early infection. Nat Med 2002, 8:114-116.
27. Geijtenbeek TB, Kwon DS, Torensma R, et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances transinfection of T cells. Cell 2000, 100:587-597.
28. Kwon DS, Gregorio G, Bitton N, et al. DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection. Immunity 2002, 16:135-144.
29. Engering A, Van Vliet SJ, Geijtenbeek TB, Van Kooyk Y. Subset of DC-SIGN(+) dendritic cells in human blood transmits HIV-1 to T lymphocytes. Blood 2002, 100:1780-1786.
30. Sol-Foulon N, Moris A, Nobile C, et al. HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread. Immunity 2002, 16:145-55.
31. Mukhtar M, Harley S, Chen P, et al. Primary isolated human brain microvascular endothelial cells express diverse HIV/SIV-associated chemokine coreceptors and DC-SIGN and L-SIGN. Virology 2002, 297:78-88.
32. Feinberg H, Mitchell DA, Drickamer K, Weis WI. Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR. Science 2001, 294:2163-2166.
33. Simons K, Toomre D. Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 2000, 1:31-39.
34. del Real G. Jimenez-Baranda S, Lacalle RA et al. Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains. J Exp Med 2002, 196:293-301.
35. Matthias LJ, Yam PT, Jiang XM, et al. Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1. Nat Immunol 2002, 3:727-732.
36. Chou CS, Ramilo O, Vitetta ES. Highly purified CD25- resting T cells cannot be infected de novo with HIV-1. Proc Natl Acad Sci USA 1997, 94:1361-1365.
37. Korin YD, Zack JA. Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cells. J Virol 1998, 72:3161-3168.
38. Eckstein DA, Penn ML, Korin YD, et al. HIV-1 actively replicates in naive CD4(+) T cells residing within human lymphoid tissues. Immunity 2001, 15:671-682.
39. Ducrey-Rundquist O, Guyader M, Trono D. Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes. J Virol 2002, 76:9103-9111.
40. Swingler S, Mann A, Jacque J, et al. HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med 1999, 5:997-1103.
41. Cicala C, Arthos J, Selig SM, et al. HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication. Proc Natl Acad Sci USA 2002, 99:9380-9385.
42. Douek DC, Brenchley JM, Betts MR, et al. HIV preferentially infects HIV-specific CD4+ T cells. Nature 2002, 417:95-98.
43. Harari A, Rizzardi GP, Ellefsen K, et al. Analysis of HIV-1- and CMV-specific memory CD4 T-cell responses during primary and chronic infection. Blood 2002, 100:1381-1387.
44. Greene WC, Peterlin BM. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Nat Med 2002, 8:673-680.
45. Segura-Totten M, Wilson KL. Virology. HIV - breaking the rules for nuclear entry. Science 2001, 294:1016-1017.
46. de Noronha CM, Sherman MP, Lin HW, et al. Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science 2001, 294:1105-1108.
47. Zimmerman C, Klein KC, Kiser PK, et al. Identification of a host protein essential for assembly of immature HIV-1 capsids. Nature 2002, 415:88-92.
48. Ono A, Freed EO. Plasma membrane rafts play a critical role in HIV-1 assembly and release. Proc Natl Acad Sci USA 2001, 98:13925-13930.
49. Miranda LR, Schaefer BC, Kupfer A, et al. Cell surface expression of the HIV-1 envelope glycoproteins is directed from intracellular CTLA-4-containing regulated secretory granules. Proc Natl Acad Sci USA 2002, 99:8031-8036.
50. Sheehy AM, Gaddis NC, Choi JD, Malim MH. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 2002, 418:646-650.
51. Pomerantz RJ. HIV: a tough viral nut to crack. Nature 2002, 418:594-595.
52. Valentin A, Rosati M, Patenaude DJ, et al. Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy. Proc Natl Acad Sci USA 2002, 99:7015-7020.
53. Marras D, Bruggeman LA, Gao F, et al. Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nat Med 2002, 8:522-526.
54. Winston JA, Bruggeman LA, Ross MD, et al. Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection. N Engl J Med. 2001, 344:1979-1984.
55. Ameisen JC. On the origin, evolution, and nature of programmed cell death: a timeline of four billion years. Cell Death Differ 2002, 9:367-393.
56. Xu XN, Screaton GR, McMichael AJ. Virus infections: escape, resistance, and counterattack. Immunity 2001, 15:867-870.
57. Ameisen JC, Pleskoff O, Lelièvre JD, DeBels F. Subversion of cell survival and cell death: viruses as enemies, tools, teachers and allies. Cell Death Differ, in press.
58. Champagne M, Mazen A. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 2001, 410:106-111.
59. Mueller YM, De Rosa SC, Hutton JA, et al. Increased CD95/Fas-induced apoptosis of HIV-specific CD8(+) T cells. Immunity 2001, 15:871-882.
60. Badley AD, Pilon AA, Landay A, Lynch DH. Mechanisms of HIV-associated lymphocyte apoptosis. Blood 2000, 96:2951-2964.
61. Brodie SJ, Lewinsohn DA, Patterson BK et al. In vivo migration and function of transferred HIV-1-specific cytotoxic T cells. Nat Med 2001, 7:1181.
62. Tan R, Xu X, Ogg GS, et al. Rapid death of adoptively transferred T cells in acquired immunodeficiency syndrome. Blood 1999, 93:1506-1510.
63. Ameisen JC. Apoptosis subversion: HIV-Nef provides both armor and sword. Nat Med 2001, 7:1181-1182.
64. Akari H, Bour S, Kao S, Adachi A, Strebel K. The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors. J Exp Med 2001, 194:1299-1311.
65. Vlahakis S, Algeciras-Schimnich A, Bou G, Heppelmann CJ, Villasis-Keever A, Collman RC, Paya CV. Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes. J Clin Invest 2002, 107:207-215.
66. Esser MT, Bess JW Jr, Suryanarayana K, et al. Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1. J Virol 2001, 75:1152-1164.
67. Castedo M, Roumier T, Blanco J, et al. Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. EMBO J 2002, 21:4070-4080.
68. Fackler OT, Baur AS. Live and let die: Nef functions beyond HIV replication. Immunity 2002, 16:493-497.
69. Geleziunas R, Xu W, Takeda K, et al. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 2001, 410:834-838.
70. Wolf D, Witte V, Laffert B, et al. HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals. Nat Med 2001, 7:1217-1224.
71. Somasundaran M, Sharkey M, Brichacek B, Stevenson M. Evidence for a cytopathogenicity determinant in HIV-1 Vpr. Proc Natl Acad Sci USA 2002, 99:9503-9508.
72. Finkel TH, Tudor-Williams G, Banda NK, et al. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat Med 1995, 1:129-134.
73. Muro-Cacho CA, Pantaleo G, Fauci AS. Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J Immunol 1995, 154:5555-5566.
74. Muthumani K, Hwang DS, Desai BM, et al. HIV-1 Vpr Induces Apoptosis through Caspase 9 in T Cells and Peripheral Blood Mononuclear Cells. J Biol Chem 2002, 277:37820-37831.
75. Lenardo MJ, Angleman SB, Bounkeua V, et al. Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env. J Virol 2002, 76:5082-5093.
76. Bolton DL, Hahn BI, Park EA, et al. Death of CD4(+) T-cell lines caused by human immunodeficiency virus type 1 does not depend on caspases or apoptosis. J Virol 2002, 76:5094-5107.
77. Green DR, Beere HM. Apoptosis. Gone but not forgotten. Nature 2000, 405:28-29.
78. Savill J, Fadok V. Corpse clearance defines the meaning of cell death. Nature 2000, 407:784-788.
79. Lima RG, Van Weyenbergh J, Saraiva EM, Barral-Netto M, Galvao-Castro B, Bou-Habib DC. The replication of HIV-1 in macrophages is enhanced after phagocytosis of apoptotic cells. J Inf Dis 2002, 185:1561.
80. th SASS Foundation Conference: Apoptosis in Cancer and Infection, Capri, 2002, p. 10 http://digilander.libero.it/celldeath/capri2002/abstracts.html/.
81. Agrawal A, Eastman QM, Schatz DG. Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 1998, 394:744-751.
82. Hoffmann JA, Reichhart JM. Drosophila innate immunity: an evolutionary perspective. Nat Immunol 2002, 3:121-126.
83. Lehrer RI, Ganz T. Defensins of vertebrate animals. Curr Opin Immunol 2002, 14:96-102.
84. Daher KA, Selsted ME, Lehrer RI. Direct inactivation of viruses by human granulocyte defensins. J Virol 1986, 60:1068-1074.
85. Cole AM, Hong T, Boo LM, et al. Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1. Proc Natl Acad Sci USA 2002, 99:1813-1818.
86. Zhang L, Yu W, He T et al. Contribution of human alpha-defensins 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor. Science 2002, 298:995-1000
87. Walker CM, Moody DJ, Stites DP, Levy JA. CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication. Science 1986, 234:1563-1566.
88. Levy JA, Mackewicz CE, Barker E. Controlling HIV pathogenesis: the role of the noncytotoxic anti-HIV response of CD8+ T cells. Immunol Today 1996, 17:217-224.
89. Sharp PA. RNA interference - 2001. Genes Dev 2001, 15:485-490.
90. Pomerantz RJ. RNA interference meets HIV-1: will silence be golden?. Nat Med 2002, 8:659-660.
91. Carmichael GG. Medicine: silencing viruses with RNA. Nature 2002, 418:379-380.
92. Paul CP, Good PD, Winer I, Engelke DR. Effective expression of small interfering RNA in human cells. Nat Biotechnol 2002, 20:505-508.
93. Yu JY, DeRuiter SL, Turner DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002, 99:6047-6052.
94. Jacque JM, Triques K, Stevenson M. Modulation of HIV-1 replication by RNA interference. Nature 2002, 418:435-438.
95. Novina CD, Murray MF, Dykxhoorn DM, et al. siRNA-directed inhibition of HIV-1 infection. Nat Med 2002, 8:681-686.
96. Lee NS, Dohjima T, Bauer G, Li H, Li MJ, Ehsani A, Salvaterra P, Rossi J. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002, 29:500-505.
97. Li H, Li WX, Ding SW. Induction and suppression of RNA silencing by an animal virus. Science 2002, 296:1319-1321.
98. Natarajan V, Lempicki RA, Sereti I, et al. Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection. Proc Natl Acad Sci USA 2002, 99:10712-10717.
99. Levine BL, Bernstein WB, Aronson NE, et al. Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection. Nat Med 2002, 8:47-53.