-
1
-
-
0024353079
-
Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
2
-
-
0028970060
-
IL-12, a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
-
Trinchieri, G. 1995. IL-12, a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 251
-
-
Trinchieri, G.1
-
3
-
-
16044363695
-
IL-12-deficient mice are defective in IFN-γ production and type 1 cytokine responses
-
Magram, J., S. E. Connaughton, R. R. Warrier, D. M. Carvajal, C. Wu, J. Ferrante, C. Stewart, U. Sarmiento, D. A. Faherty, and M. K. Gately. 1996. IL-12-deficient mice are defective in IFN-γ production and type 1 cytokine responses Immunity 4:471.
-
(1996)
Immunity
, vol.4
, pp. 471
-
-
Magram, J.1
Connaughton, S.E.2
Warrier, R.R.3
Carvajal, D.M.4
Wu, C.5
Ferrante, J.6
Stewart, C.7
Sarmiento, U.8
Faherty, D.A.9
Gately, M.K.10
-
4
-
-
0031571205
-
Characterization of IL-12 receptor β1-chain-deficient mice: IL-12 receptor β1 is an essential component of the functional mouse IL-12 receptor
-
Wu, C., J. Ferrante, M. K. Gately, and J. Magram. 1997. Characterization of IL-12 receptor β1-chain-deficient mice: IL-12 receptor β1 is an essential component of the functional mouse IL-12 receptor. J. Immunol. 159:1658.
-
(1997)
J. Immunol.
, vol.159
, pp. 1658
-
-
Wu, C.1
Ferrante, J.2
Gately, M.K.3
Magram, J.4
-
5
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan, M. H., Y. L. Sun, T. Hoey, and M. J. Grusby. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:174.
-
(1996)
Nature
, vol.382
, pp. 174
-
-
Kaplan, M.H.1
Sun, Y.L.2
Hoey, T.3
Grusby, M.J.4
-
6
-
-
0028949152
-
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 development pathways: Application to autoimmune disease therapy
-
Kuchroo, V. K., M. P. Das, J. A. Brown, A. M. Ranger, S. S. Zamvil, R. A. Sobel, H. L. Weiner, N. Nabavi, and L. H. Glimcher. 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 development pathways: application to autoimmune disease therapy. Cell 80:707.
-
(1995)
Cell
, vol.80
, pp. 707
-
-
Kuchroo, V.K.1
Das, M.P.2
Brown, J.A.3
Ranger, A.M.4
Zamvil, S.S.5
Sobel, R.A.6
Weiner, H.L.7
Nabavi, N.8
Glimcher, L.H.9
-
7
-
-
0029838995
-
Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in NOD mice
-
Mueller, R., T. Krahl, and N. Sarvetnick. 1996. Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in NOD mice. J. Exp. Med. 184:1093.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1093
-
-
Mueller, R.1
Krahl, T.2
Sarvetnick, N.3
-
8
-
-
0031131886
-
A noncytolytic IL-10/Fc fusion protein prevents diabetes, blocks autoimmunity, and promotes suppressor phenomena in NOD mice
-
Zheng, X. X., A. W. Steele, W. W. Hancock, A. C. Stevens, P. W. Nickerson, P. Roy-Chaudhury, Y. Tian, and T. B. Strom. 1997. A noncytolytic IL-10/Fc fusion protein prevents diabetes, blocks autoimmunity, and promotes suppressor phenomena in NOD mice. J. Immunol. 158:4507.
-
(1997)
J. Immunol.
, vol.158
, pp. 4507
-
-
Zheng, X.X.1
Steele, A.W.2
Hancock, W.W.3
Stevens, A.C.4
Nickerson, P.W.5
Roy-Chaudhury, P.6
Tian, Y.7
Strom, T.B.8
-
9
-
-
0031202296
-
Neutralizing IL-12 during induction of murine acute graft-versus-host disease polarizes the cytokine profile toward a Th2-type alloimmune response and confers long-term protection from disease
-
Williamson, E., P. Garside, J. A. Bradley, I. A. R. More, and A. M. Mowat. 1997. Neutralizing IL-12 during induction of murine acute graft-versus-host disease polarizes the cytokine profile toward a Th2-type alloimmune response and confers long-term protection from disease. J. Immunol. 159:1208.
-
(1997)
J. Immunol.
, vol.159
, pp. 1208
-
-
Williamson, E.1
Garside, P.2
Bradley, J.A.3
More, I.A.R.4
Mowat, A.M.5
-
10
-
-
0028966091
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin-12
-
Leonard, J. P., K. E. Waldburger, and S. J. Goldman. 1995. Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin-12. J. Exp. Med. 181:381.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 381
-
-
Leonard, J.P.1
Waldburger, K.E.2
Goldman, S.J.3
-
11
-
-
0028861975
-
Antibodies to interleukin-12 abrogate established experimental colitis in mice
-
Neurath, M. F., I. Fuss, B. L. Kelsall, E. Stuber, and W. Strober. 1995. Antibodies to interleukin-12 abrogate established experimental colitis in mice. J. Exp. Med. 182:1281.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1281
-
-
Neurath, M.F.1
Fuss, I.2
Kelsall, B.L.3
Stuber, E.4
Strober, W.5
-
12
-
-
0028821825
-
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
-
Gavett, S. H., D. J. O'Hearn, X. Li, S. K. Huang, F. D. Finkelman, and M. Wills-Karp. 1995. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J. Exp. Med. 182:1527.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1527
-
-
Gavett, S.H.1
O'Hearn, D.J.2
Li, X.3
Huang, S.K.4
Finkelman, F.D.5
Wills-Karp, M.6
-
13
-
-
0026729563
-
Heart allografts in murine systems: The differential activation of Th2-like effector cells in peripheral tolerance
-
Takeuchi, T., R. P. Lowry, and B. Konieczny. 1992. Heart allografts in murine systems: the differential activation of Th2-like effector cells in peripheral tolerance. Transplantation 53:1281.
-
(1992)
Transplantation
, vol.53
, pp. 1281
-
-
Takeuchi, T.1
Lowry, R.P.2
Konieczny, B.3
-
14
-
-
0029664599
-
Prevention of Th1 responses is critical for tolerance
-
Chen, N., Q. Gao, and E. H. Field. 1996. Prevention of Th1 responses is critical for tolerance. Transplantation 61:1076.
-
(1996)
Transplantation
, vol.61
, pp. 1076
-
-
Chen, N.1
Gao, Q.2
Field, E.H.3
-
15
-
-
0031568550
-
Type 2 helper T cell-type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients
-
Onodera, K., W. W. Hancock, E. Graser, M. Lehmann, M. H. Sayegh, T. B. Strom, H. D. Volk, and J. W. Kupiec-Weglinski. 1997. Type 2 helper T cell-type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients. J. Immunol. 158:1572.
-
(1997)
J. Immunol.
, vol.158
, pp. 1572
-
-
Onodera, K.1
Hancock, W.W.2
Graser, E.3
Lehmann, M.4
Sayegh, M.H.5
Strom, T.B.6
Volk, H.D.7
Kupiec-Weglinski, J.W.8
-
16
-
-
13344249764
-
Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival
-
Qin, L., K. D. Chavin, Y. Ding, H. Tahara, J. P. Favaro, J. E. Woodward, T. Suzuki, P. D. Robbins, M. T. Lotze, and J. S. Bromberg. 1996. Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival. J. Immunol. 156:2316.
-
(1996)
J. Immunol.
, vol.156
, pp. 2316
-
-
Qin, L.1
Chavin, K.D.2
Ding, Y.3
Tahara, H.4
Favaro, J.P.5
Woodward, J.E.6
Suzuki, T.7
Robbins, P.D.8
Lotze, M.T.9
Bromberg, J.S.10
-
17
-
-
0028903939
-
CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
-
Sayegh, M. H., E. Akalin, W. W. Hancock, M. E. Russell, and C. B. Carpenter. 1995. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J. Exp. Med. 181:1869.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1869
-
-
Sayegh, M.H.1
Akalin, E.2
Hancock, W.W.3
Russell, M.E.4
Carpenter, C.B.5
-
18
-
-
0028997995
-
IL-2 knockout recipient mice reject islet cell allografts
-
Steiger, J., P. W. Nickerson, W. Steurer, M. Moscovitch-Lopatin, and T. B. Strom. 1995. IL-2 knockout recipient mice reject islet cell allografts. J. Immunol. 155:489.
-
(1995)
J. Immunol.
, vol.155
, pp. 489
-
-
Steiger, J.1
Nickerson, P.W.2
Steurer, W.3
Moscovitch-Lopatin, M.4
Strom, T.B.5
-
19
-
-
0029886947
-
Prolonged islet allograft acceptance in the absence of interleukin-4 expression
-
Nickerson, P. W., X. X. Zheng, J. Steiger, A. W. Steele, W. Steurer, P. Roy-Chaudhury, W. Muller, and T. B. Strom. 1996. Prolonged islet allograft acceptance in the absence of interleukin-4 expression. Transpl. Immunol. 4:81.
-
(1996)
Transpl. Immunol.
, vol.4
, pp. 81
-
-
Nickerson, P.W.1
Zheng, X.X.2
Steiger, J.3
Steele, A.W.4
Steurer, W.5
Roy-Chaudhury, P.6
Muller, W.7
Strom, T.B.8
-
20
-
-
0031091771
-
Blocking the CD28-B7 T cell costimulation pathway induces long-term cardiac allograft acceptance in the absence of IL-4
-
Lakkis, F. G., B. T. Konieczny, S. Saleem, F. K. Baddoura, P. S. Linsley, D. Z. Alexander, R. P. Lowry, T. C. Pearson, and C. P. Larsen. 1997. Blocking the CD28-B7 T cell costimulation pathway induces long-term cardiac allograft acceptance in the absence of IL-4. J. Immunol. 158:2443.
-
(1997)
J. Immunol.
, vol.158
, pp. 2443
-
-
Lakkis, F.G.1
Konieczny, B.T.2
Saleem, S.3
Baddoura, F.K.4
Linsley, P.S.5
Alexander, D.Z.6
Lowry, R.P.7
Pearson, T.C.8
Larsen, C.P.9
-
21
-
-
0029020011
-
Administration of noncytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation
-
Zheng, X. X., A. W. Steele, P. W. Nickerson, W. Steurer, J. Steiger, and T. B. Strom. 1995. Administration of noncytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation. J. Immunol. 154:5590.
-
(1995)
J. Immunol.
, vol.154
, pp. 5590
-
-
Zheng, X.X.1
Steele, A.W.2
Nickerson, P.W.3
Steurer, W.4
Steiger, J.5
Strom, T.B.6
-
22
-
-
0030240073
-
IL-12 antagonism induces Th2 responses, yet exacerbates cardiac allograft rejection
-
Piccotti, J. R., S. Y. Chan, R. E. Goodman, J. Magram, E. J. Eichwald, and D. K. Bishop. 1996. IL-12 antagonism induces Th2 responses, yet exacerbates cardiac allograft rejection. J. Immunol. 157:1951.
-
(1996)
J. Immunol.
, vol.157
, pp. 1951
-
-
Piccotti, J.R.1
Chan, S.Y.2
Goodman, R.E.3
Magram, J.4
Eichwald, E.J.5
Bishop, D.K.6
-
23
-
-
0030470416
-
The role of interleukin-4 in the induction phase of allogeneic neonatal tolerance
-
Gao, Q., N. Chen, T. M. Rouse, and E. H. Field. 1996. The role of interleukin-4 in the induction phase of allogeneic neonatal tolerance. Transplantation 62:1847.
-
(1996)
Transplantation
, vol.62
, pp. 1847
-
-
Gao, Q.1
Chen, N.2
Rouse, T.M.3
Field, E.H.4
-
24
-
-
0030006103
-
T cell regulation in adult transplantation tolerance
-
Davies, J. D., G. Martin, J. Phillips, S. E. Marshall, S. P. Cobbold, and H. Waldmann. 1996. T cell regulation in adult transplantation tolerance. J. Immunol. 157:529.
-
(1996)
J. Immunol.
, vol.157
, pp. 529
-
-
Davies, J.D.1
Martin, G.2
Phillips, J.3
Marshall, S.E.4
Cobbold, S.P.5
Waldmann, H.6
-
25
-
-
0029068458
-
Critical role of interleukin-4 in the induction of neonatal transplantation tolerance
-
Donckier, V., M. Wissing, C. Bruyns, D. Abramwicz, M. Lybin, M. L. Vanderhaeghen, and M. Goldman. 1995. Critical role of interleukin-4 in the induction of neonatal transplantation tolerance. Transplantation 59:1571.
-
(1995)
Transplantation
, vol.59
, pp. 1571
-
-
Donckier, V.1
Wissing, M.2
Bruyns, C.3
Abramwicz, D.4
Lybin, M.5
Vanderhaeghen, M.L.6
Goldman, M.7
-
26
-
-
0028031970
-
Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo
-
Lee, R. S., M. J. Grusby, L. H. Glimcher, H. J. Winn, and H. Auchincloss, Jr. 1994. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J. Exp. Med. 179:865.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 865
-
-
Lee, R.S.1
Grusby, M.J.2
Glimcher, L.H.3
Winn, H.J.4
Auchincloss Jr., H.5
-
27
-
-
0031027528
-
Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation
-
Strehlau, J., M. Pavlakis, M. Lipman, M. Shapiro, L. Vasconcellos, W. Harmon, and T. B. Strom. 1997. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation. Proc. Natl. Acad. Sci. USA 94:695.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 695
-
-
Strehlau, J.1
Pavlakis, M.2
Lipman, M.3
Shapiro, M.4
Vasconcellos, L.5
Harmon, W.6
Strom, T.B.7
-
28
-
-
0028308632
-
Presentation and recognition of major and minor histocompatibility antigens
-
Warrens, A. N., G. Lombardi, and R. I. Lechler. 1994. Presentation and recognition of major and minor histocompatibility antigens. Transpl. Immunol. 2:103.
-
(1994)
Transpl. Immunol.
, vol.2
, pp. 103
-
-
Warrens, A.N.1
Lombardi, G.2
Lechler, R.I.3
-
29
-
-
0028176656
-
Indirect presentation of MHC antigens in transplantation
-
Shoskes, D. A., and K. J. Wood. 1994. Indirect presentation of MHC antigens in transplantation. Immunol. Today 15:32.
-
(1994)
Immunol. Today
, vol.15
, pp. 32
-
-
Shoskes, D.A.1
Wood, K.J.2
-
30
-
-
0025941970
-
Evidence for direct and indirect pathways in the generation of the alloimmune response against pancreatic islets
-
Stock, P. G., N. L. Ascher, S. Chen, J. Field, F. H. Bach, and D. E. Sutherland. 1991. Evidence for direct and indirect pathways in the generation of the alloimmune response against pancreatic islets. Transplantation 52:704.
-
(1991)
Transplantation
, vol.52
, pp. 704
-
-
Stock, P.G.1
Ascher, N.L.2
Chen, S.3
Field, J.4
Bach, F.H.5
Sutherland, D.E.6
-
31
-
-
0030272486
-
The Th1/Th2 paradigm and the allograft response
-
Strom, T. B., P. Roy-Chaudhury, R. Manfro, X. X. Zheng, P. W. Nickerson, K. Wood, and A. Bushell. 1996. The Th1/Th2 paradigm and the allograft response. Curr. Opin. Immunol. 8:688.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 688
-
-
Strom, T.B.1
Roy-Chaudhury, P.2
Manfro, R.3
Zheng, X.X.4
Nickerson, P.W.5
Wood, K.6
Bushell, A.7
-
32
-
-
0030951832
-
Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival?
-
Piccotti, J. R., S. Y. Chan, A. M. VanBuskirk, E. J. Eichwald, and D. K. Bishop. 1997. Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival? Transplantation 63:619.
-
(1997)
Transplantation
, vol.63
, pp. 619
-
-
Piccotti, J.R.1
Chan, S.Y.2
Vanbuskirk, A.M.3
Eichwald, E.J.4
Bishop, D.K.5
-
33
-
-
0031571310
-
IL-4 expression by grafts from transgenic mice fails to prevent allograft rejection
-
Mueller, R., J. D. Davis, T. Krahl, and N. Sarvetnick. 1997. IL-4 expression by grafts from transgenic mice fails to prevent allograft rejection. J. Immunol. 159: 1599.
-
(1997)
J. Immunol.
, vol.159
, pp. 1599
-
-
Mueller, R.1
Davis, J.D.2
Krahl, T.3
Sarvetnick, N.4
-
34
-
-
0030266857
-
Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease
-
Seder, R. A., B. L. Kelsall, and D. Jankovic. 1996. Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease. J. Immunol. 157:2745.
-
(1996)
J. Immunol.
, vol.157
, pp. 2745
-
-
Seder, R.A.1
Kelsall, B.L.2
Jankovic, D.3
|