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Volumn 164, Issue 1, 2000, Pages 512-521

Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner

Author keywords

[No Author keywords available]

Indexed keywords

CD40 LIGAND MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 0033980596     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.1.512     Document Type: Article
Times cited : (193)

References (66)
  • 1
    • 0032904420 scopus 로고    scopus 로고
    • Induction of immunological tolerance for transplantation
    • Rossini, A. A., D. L. Greiner, and J. P. Mordes. 1999. Induction of immunological tolerance for transplantation. Physiol. Rev. 79:99.
    • (1999) Physiol. Rev. , vol.79 , pp. 99
    • Rossini, A.A.1    Greiner, D.L.2    Mordes, J.P.3
  • 4
    • 0026476032 scopus 로고
    • CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation
    • Noelle, R. J., J. A. Ledbetter, and A. Aruffo. 1992. CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. Immunol. Today 13:431.
    • (1992) Immunol. Today , vol.13 , pp. 431
    • Noelle, R.J.1    Ledbetter, J.A.2    Aruffo, A.3
  • 7
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle, R. J., M. Roy, D. M. Shepherd, I. Stamenkovic, J. A. Ledbetter, and A. Aruffo. 1992. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc. Natl. Acad. Sci. USA 89:6550.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6550
    • Noelle, R.J.1    Roy, M.2    Shepherd, D.M.3    Stamenkovic, I.4    Ledbetter, J.A.5    Aruffo, A.6
  • 8
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal, I. S., and R. A. Flavell. 1998. CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 16:111.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 111
    • Grewal, I.S.1    Flavell, R.A.2
  • 10
    • 0033062447 scopus 로고    scopus 로고
    • Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody
    • Rossini, A. A., J. P. Mordes, T. G. Markees, N. E. Phillips, E. J. Gordon, and D. L. Greiner. 1999. Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody. Transplant. Proc. 31:629.
    • (1999) Transplant. Proc. , vol.31 , pp. 629
    • Rossini, A.A.1    Mordes, J.P.2    Markees, T.G.3    Phillips, N.E.4    Gordon, E.J.5    Greiner, D.L.6
  • 12
    • 0033056599 scopus 로고    scopus 로고
    • Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody
    • Markees, T. G., N. E. Phillips, E. J. Gordon, R. J. Noelle, J. P. Mordes, D. L. Greiner, and A. A. Rossini. 1999. Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody. Transplant. Proc. 31:884.
    • (1999) Transplant. Proc. , vol.31 , pp. 884
    • Markees, T.G.1    Phillips, N.E.2    Gordon, E.J.3    Noelle, R.J.4    Mordes, J.P.5    Greiner, D.L.6    Rossini, A.A.7
  • 13
    • 0031704504 scopus 로고    scopus 로고
    • Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody
    • Markees, T. G., N. E. Phillips, E. J. Gordon, R. J. Noelle, J. P. Mordes, D. L. Greiner, and A. A. Rossini. 1998. Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody. Transplant. Proc. 30:2444.
    • (1998) Transplant. Proc. , vol.30 , pp. 2444
    • Markees, T.G.1    Phillips, N.E.2    Gordon, E.J.3    Noelle, R.J.4    Mordes, J.P.5    Greiner, D.L.6    Rossini, A.A.7
  • 15
    • 0030860995 scopus 로고    scopus 로고
    • Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand
    • Markees, T. G., N. E. Phillips, R. J. Noelle, L. D. Shultz, J. P. Mordes, D. L. Greiner, and A. A. Rossini. 1997. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation 64:329.
    • (1997) Transplantation , vol.64 , pp. 329
    • Markees, T.G.1    Phillips, N.E.2    Noelle, R.J.3    Shultz, L.D.4    Mordes, J.P.5    Greiner, D.L.6    Rossini, A.A.7
  • 22
    • 0028466130 scopus 로고
    • Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
    • Kearney, E. R., K. A. Pape, D. Y. Loh, and M. K. Jenkins. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1:327.
    • (1994) Immunity , vol.1 , pp. 327
    • Kearney, E.R.1    Pape, K.A.2    Loh, D.Y.3    Jenkins, M.K.4
  • 23
    • 0025176675 scopus 로고
    • A simple screening method for transgenic mice using the polymerase chain reaction
    • Chen, S. Z., and G. A. Evans. 1990. A simple screening method for transgenic mice using the polymerase chain reaction. BioTechniques 8:32.
    • (1990) BioTechniques , vol.8 , pp. 32
    • Chen, S.Z.1    Evans, G.A.2
  • 24
    • 0025286125 scopus 로고
    • A novel type of aberrant T cell receptor α-chain gene rearrangement: Implications for allelic exclusion and the V-J recombination process
    • Hue, I., J. Trucy, C. McCoy, D. Couez, B. Malissen, and M. Malissen. 1990. A novel type of aberrant T cell receptor α-chain gene rearrangement: implications for allelic exclusion and the V-J recombination process. J. Immunol. 144:4410.
    • (1990) J. Immunol. , vol.144 , pp. 4410
    • Hue, I.1    Trucy, J.2    McCoy, C.3    Couez, D.4    Malissen, B.5    Malissen, M.6
  • 25
    • 0027493906 scopus 로고
    • In vivo CD40-gp39 interactions are essential for thymusdependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39
    • Foy, T. M., D. M. Shepherd, F. H. Durie, A. Aruffo, J. A. Ledbetter, and R. J. Noelle. 1993. In vivo CD40-gp39 interactions are essential for thymusdependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. J. Exp. Med. 178:1567.
    • (1993) J. Exp. Med. , vol.178 , pp. 1567
    • Foy, T.M.1    Shepherd, D.M.2    Durie, F.H.3    Aruffo, A.4    Ledbetter, J.A.5    Noelle, R.J.6
  • 26
    • 9644312932 scopus 로고
    • Care and handling of laboratory animals. Survival surgery: Removal of the spleen or thymus
    • J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds. Wiley, New York
    • Reeves, J. P., and P. A. Reeves. 1994. Care and handling of laboratory animals. Survival surgery: removal of the spleen or thymus. In Current Protocols in Immunology. J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds. Wiley, New York, p. 1.10.1.
    • (1994) Current Protocols in Immunology , pp. 1101
    • Reeves, J.P.1    Reeves, P.A.2
  • 27
    • 0000363116 scopus 로고
    • In vivo depletion of CD4- and CD8-specific T cells
    • J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds. Wiley, New York
    • Kruisbeek, A. M. 1994. In vivo depletion of CD4- and CD8-specific T cells. In Current Protocols in Immunology. J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds. Wiley, New York, p. 4.1.1.
    • (1994) Current Protocols in Immunology , pp. 411
    • Kruisbeek, A.M.1
  • 28
    • 0141839298 scopus 로고
    • Anatomy
    • H. L. Foster, J. D. Small, and J. G. Fox, eds. Academic, New York
    • Cook, M. J. 1983. Anatomy. In The Mouse in Biomedical Research. H. L. Foster, J. D. Small, and J. G. Fox, eds. Academic, New York, p. 101.
    • (1983) The Mouse in Biomedical Research , pp. 101
    • Cook, M.J.1
  • 29
    • 0029959203 scopus 로고    scopus 로고
    • Abnormalities in the export and fate of recent thymic emigrants in diabetes-prone BB/W rats
    • Zadeh, H. H., D. L. Greiner, D. Y. Wu, F. Tausche, and I. Goldschneider, 1996. Abnormalities in the export and fate of recent thymic emigrants in diabetes-prone BB/W rats. Autoimmunity 24:35.
    • (1996) Autoimmunity , vol.24 , pp. 35
    • Zadeh, H.H.1    Greiner, D.L.2    Wu, D.Y.3    Tausche, F.4    Goldschneider, I.5
  • 31
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan, E. L., and P. Meier. 1958. Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53:457.
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 457
    • Kaplan, E.L.1    Meier, P.2
  • 34
    • 0031022715 scopus 로고    scopus 로고
    • Accessory molecule and costimulation requirements for CD4 T cell response
    • Croft, M., and C. Dubey. 1997. Accessory molecule and costimulation requirements for CD4 T cell response. CRC Crit. Rev. Immunol. 17:89.
    • (1997) CRC Crit. Rev. Immunol. , vol.17 , pp. 89
    • Croft, M.1    Dubey, C.2
  • 35
    • 0033534678 scopus 로고    scopus 로고
    • From TCR engagement to T cell activation: A kinetic view of T cell behavior
    • Lanzavecchia, A., G. Iezzi, and A. Viola. 1999. From TCR engagement to T cell activation: a kinetic view of T cell behavior. Cell 96:1.
    • (1999) Cell , vol.96 , pp. 1
    • Lanzavecchia, A.1    Iezzi, G.2    Viola, A.3
  • 36
    • 0031977605 scopus 로고    scopus 로고
    • The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells
    • Mackey, M. F., R. J. Barth, Jr., and R. J. Noelle. 1998. The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells. J. Leukocyte Biol. 63:418.
    • (1998) J. Leukocyte Biol. , vol.63 , pp. 418
    • Mackey, M.F.1    Barth R.J., Jr.2    Noelle, R.J.3
  • 37
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • Van Parijs, L., A. Ibraghimov, and A. K. Abbas. 1996. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 4:321.
    • (1996) Immunity , vol.4 , pp. 321
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 39
    • 0030006733 scopus 로고    scopus 로고
    • CD28 costimulation prevents cell death during primary T cell activation
    • Noel, P. J., L. H. Boise, J. M. Green, and C. B. Thompson. 1996. CD28 costimulation prevents cell death during primary T cell activation. J. Immunol. 157:636.
    • (1996) J. Immunol. , vol.157 , pp. 636
    • Noel, P.J.1    Boise, L.H.2    Green, J.M.3    Thompson, C.B.4
  • 40
    • 0031658184 scopus 로고    scopus 로고
    • CD40 ligand signals optimize T helper cell cytokine production: Role in Th2 development and induction of germinal centers
    • Poudrier, J., D. Van Essen, S. Morales-Alcelay, T. Leanderson, S. Bergthorsdottir, and D. Gray. 1998. CD40 ligand signals optimize T helper cell cytokine production: role in Th2 development and induction of germinal centers. Eur. J. Immunol. 28:3371.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3371
    • Poudrier, J.1    Van Essen, D.2    Morales-Alcelay, S.3    Leanderson, T.4    Bergthorsdottir, S.5    Gray, D.6
  • 41
    • 0031049085 scopus 로고    scopus 로고
    • The natural killer gene complex: A genetic basis for understanding natural killer cell function and innate immunity
    • Brown, M. G., A. A. Scalzo, K. Matsumoto, and W. M. Yokoyama. 1997. The natural killer gene complex: A genetic basis for understanding natural killer cell function and innate immunity. Immunol. Rev. 155:53.
    • (1997) Immunol. Rev. , vol.155 , pp. 53
    • Brown, M.G.1    Scalzo, A.A.2    Matsumoto, K.3    Yokoyama, W.M.4
  • 43
    • 0025602793 scopus 로고
    • Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity
    • Webb, S., C. Morris, and J. Sprent. 1990. Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell 63:1249.
    • (1990) Cell , vol.63 , pp. 1249
    • Webb, S.1    Morris, C.2    Sprent, J.3
  • 44
    • 0027457378 scopus 로고
    • Peripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus
    • Waanders, G. A., A. N. Shakhov, W. Held, O. Karapetian, H. Acha-Orbea, and H. R. MacDonald. 1993. Peripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus. J. Exp. Med. 177:1359.
    • (1993) J. Exp. Med. , vol.177 , pp. 1359
    • Waanders, G.A.1    Shakhov, A.N.2    Held, W.3    Karapetian, O.4    Acha-Orbea, H.5    MacDonald, H.R.6
  • 47
    • 0025865438 scopus 로고
    • A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus
    • Choi, Y., J. W. Kappler, and P. Marrack. 1991. A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus. Nature 350:203.
    • (1991) Nature , vol.350 , pp. 203
    • Choi, Y.1    Kappler, J.W.2    Marrack, P.3
  • 49
    • 0032526283 scopus 로고    scopus 로고
    • Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
    • Wekerle, T., M. H. Sayegh, J. Hill, Y. Zhao, A. Chandraker, K. G. Swenson, G. Zhao, and M. Sykes. 1998. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance. J. Exp. Med. 187:2037.
    • (1998) J. Exp. Med. , vol.187 , pp. 2037
    • Wekerle, T.1    Sayegh, M.H.2    Hill, J.3    Zhao, Y.4    Chandraker, A.5    Swenson, K.G.6    Zhao, G.7    Sykes, M.8
  • 50
    • 0027218331 scopus 로고
    • Superantigen-driven peripheral deletion of T cells. Apoptosis occurs in cells that have lost the α/β T cell receptor
    • Huang, L., and I. N. Crispe. 1993. Superantigen-driven peripheral deletion of T cells. Apoptosis occurs in cells that have lost the α/β T cell receptor. J. Immunol. 151:1844.
    • (1993) J. Immunol. , vol.151 , pp. 1844
    • Huang, L.1    Crispe, I.N.2
  • 51
    • 0026068601 scopus 로고
    • +T cells in mice tolerant to Staphylococcus aureus enterotoxin B
    • +T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature 349:245.
    • (1991) Nature , vol.349 , pp. 245
    • Kawabe, Y.1    Ochi, A.2
  • 52
    • 0025908321 scopus 로고
    • Peripheral selection of the T cell repertoire
    • Rocha, B., and H. Von Boehmer. 1991. Peripheral selection of the T cell repertoire. Science 251:1225.
    • (1991) Science , vol.251 , pp. 1225
    • Rocha, B.1    Von Boehmer, H.2
  • 54
    • 0029817181 scopus 로고    scopus 로고
    • The fate of adoptively transferred antigen-specific T cells in vivo
    • Zhang, L. 1996. The fate of adoptively transferred antigen-specific T cells in vivo. Eur. J. Immunol. 26:2208.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2208
    • Zhang, L.1
  • 57
    • 0033557716 scopus 로고    scopus 로고
    • The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival
    • Judge, T. A., Z. H. Wu, X. G. Zheng, A. H. Sharpe, M. H. Sayegh, and L. A. Turka. 1999. The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival. J. Immunol. 162:1947.
    • (1999) J. Immunol. , vol.162 , pp. 1947
    • Judge, T.A.1    Wu, Z.H.2    Zheng, X.G.3    Sharpe, A.H.4    Sayegh, M.H.5    Turka, L.A.6
  • 58
    • 0031154577 scopus 로고    scopus 로고
    • CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice
    • Tivol, E. A., S. D. Boyd, S. McKeon, F. Borriello, P. Nickerson, T. B. Strom, and A. H. Sharpe. 1997. CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice. J. Immunol. 158:5091.
    • (1997) J. Immunol. , vol.158 , pp. 5091
    • Tivol, E.A.1    Boyd, S.D.2    McKeon, S.3    Borriello, F.4    Nickerson, P.5    Strom, T.B.6    Sharpe, A.H.7
  • 61
    • 0030300154 scopus 로고    scopus 로고
    • The complexities of T-cell co-stimulation: CD28 and beyond
    • Sperling, A. I., and J. A. Bluestone. 1996. The complexities of T-cell co-stimulation: CD28 and beyond. Immunol. Rev. 153:155.
    • (1996) Immunol. Rev. , vol.153 , pp. 155
    • Sperling, A.I.1    Bluestone, J.A.2
  • 62
    • 0031464292 scopus 로고    scopus 로고
    • Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allograft recipients
    • Sayegh, M. H., X. G. Zheng, C. Magee, W. W. Hancock, and L. A. Turka. 1997. Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allograft recipients. Transplantation 64:1646.
    • (1997) Transplantation , vol.64 , pp. 1646
    • Sayegh, M.H.1    Zheng, X.G.2    Magee, C.3    Hancock, W.W.4    Turka, L.A.5
  • 65
    • 0028237260 scopus 로고
    • Anergic T cells as suppressor cells in vitro
    • Lombardi, G., S. Sidhu, R. Batchelor, and R. Lechler. 1994. Anergic T cells as suppressor cells in vitro. Science 264:1587.
    • (1994) Science , vol.264 , pp. 1587
    • Lombardi, G.1    Sidhu, S.2    Batchelor, R.3    Lechler, R.4


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