Inhibition of γ-aminobutyric acid uptake: Anatomy, physiology and effects against epileptic seizures

European Journal of Pharmacology

Volumn 479, Issue 1-3, 2003, Pages 127-137

  Dalby, Nils Ole ^a  

^a H LUNDBECK A S   (Denmark)

Author keywords

Epilepsy; Extrasynaptic; GABA transport; GAT 1 (GABA transporter 1); GAT 2 (GABA transporter 2); GAT 3 (GABA transporter 3); Tiagabine; Tonic conductance

Indexed keywords

1 (4,4 DIPHENYL 3 BUTENYL)GUVACINE; 1 (4,4 DIPHENYL 3 BUTENYL)NIPECOTIC ACID; 1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 1 [2 [4,4' BIS(TRIFLUOROMETHYL)BENZHYDRYLOXY]ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 1 [2 [TRIS(4 METHOXYPHENYL)METHOXY]ETHYL] 3 PIPERIDINECARBOXYLIC ACID; 1 [3 (9H CARBAZOL 9 YL) 1 PROPYL] 4 (2 METHOXYPHENYL) 4 PIPERIDINOL; 1 [3 (9H CARBAZOL 9 YL) 1 PROPYL] 4 (4 METHOXYPHENYL) 4 PIPERIDINOL; 1 [[3 (CARBAZOL 9 YL) 2 METHYL]PROPYL] 4 PHENYL 4 PIPERIDINOL; 3 AMINOCYCLOHEXANECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID TRANSPORTER 1; 4 AMINOBUTYRIC ACID TRANSPORTER 2; 4 AMINOBUTYRIC ACID TRANSPORTER 3; 4,5,6,7 TETRAHYDROISOXAZOLO[4,5 C]PYRIDIN 3 OL; AMINO ACID TRANSPORTER; ANTICONVULSIVE AGENT; BETA ALANINE; BETAINE 4 AMINOBUTYRIC ACID TRANSPORTER 1; GABOXADOL; GUVACINE; NIPECOTIC ACID; NNC 052045; NNC 052090; NNC 052101; PROTEIN INHIBITOR; TIAGABINE; UNCLASSIFIED DRUG; VESICULAR INHIBITORY AMINO ACID TRANSPORTER;

4 AMINOBUTYRIC ACID UPTAKE; ANTICONVULSANT ACTIVITY; BLOOD BRAIN BARRIER; BRAIN REGION; CONCENTRATION RESPONSE; DRUG BINDING SITE; DRUG EFFECT; DRUG PENETRATION; DRUG PROTEIN BINDING; EXCITATORY POSTSYNAPTIC POTENTIAL; GABAERGIC SYSTEM; HUMAN; INHIBITORY POSTSYNAPTIC POTENTIAL; NEUROANATOMY; NEUROPHYSIOLOGY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SEIZURE; SYNAPSE; TRANSPORT KINETICS;

EID: 0242660375     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.08.063     Document Type: Article

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