Functional characterization of the betaine/γ/-aminobutyric acid transporter BGT-1 expressed in Xenopus oocytes

Journal of Biological Chemistry

Volumn 274, Issue 24, 1999, Pages 16709-16716

  Matskevitch, Ioulia ^a,b   Wagner, Carsten A ^a,c,d   Stegen, Carola ^a   Bröer, Stefan ^a   Noll, Birgitta ^a   Risler, Teut ^a   Kwon, H Moo ^b   Handler, Joseph S ^b   Waldegger, Siegfried ^a   Busch, Andreas E ^a   Lang, Florian ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

^d Interdisc Clinical Research Center   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; BETA ALANINE; BETAINE; CARRIER PROTEIN; CHLORIDE ION; DIAMINOBUTYRIC ACID; DIMETHYLGLYCINE; GLYCINE; PROLINE; PROTEIN BGT 1; QUINIDINE; SARCOSINE; SODIUM ION; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; NONHUMAN; OSMOREGULATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; XENOPUS;

ANIMALS; BETAINE; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CATIONS, MONOVALENT; CHLORIDES; DOGS; ELECTRIC CONDUCTIVITY; GAMMA-AMINOBUTYRIC ACID; MODELS, BIOLOGICAL; OOCYTES; PATCH-CLAMP TECHNIQUES; RECOMBINANT PROTEINS; SODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; XENOPUS;

ANIMALIA;

EID: 0033546413     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.24.16709     Document Type: Article

References (30)

1. Lang, F., Busch, G. L., Ritter, M., Völkl, H., Waldegger, S., Gulbins, E. J., and Häussinger, D. (1998) Physiol Rev. 78, 247-306
2. Lang, F., Busch, G. L., and Völkl, H. (1998) Cell. Physiol. Biochem. 8, 1-45
3. Burg, M. B. (1995) Am. J. Physiol. 268, F983-F996
4. Handler, J. S., and Kwon, H. M. (1993) Am. J. Physiol. 265, C1449-C1455
5. Burg, M. B. (1994) J. Exp. Zool. 268, 171-175
6. Burg, M. B., Kwon, E. D., and Kultz, D. (1996) FASEB J. 10, 1598-1606
7. Yamauchi, A., Uchida, S., Kwon, H. M., Preston, A. S., Robey, R. B., Garcia-Perez, A., Burg, M., and Handler, J. S. (1992) J. Biol. Chem. 267, 649-652
8. Rasola, A., Galietta, L. J. V., Barone, V., Romeo, G., and Bagnasco, S. (1995) FEBS Lett. 373, 229-233
9. Borden, L. A., Smith, K. E., Gustafson, E. L., Branchek, T. A., and Weinshank, R. L. (1995) J. Neurochem. 64, 977-984
10. Lopez-Corcuera, B., Liu, Q.-R., Mandiyan, S., Nelson, H., and Nelson, N. (1992) J. Biol. Chem. 267, 17491-17493
11. Uchida, S., Kwon, H. M., Yamauchi, A., Preston, A. S., Marumo, F., and Handler, J. S. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 8230-8234
12. Smith, K. E., Borden, L. A., Wang, C.-H. D., Hartig, P. R., Branchek, T. A., and Weinshank, R. L. (1992) Mol. Pharmacol. 42, 563-569
13. Kwon, H. M., Yamauchi, A., Uchida, S., Preston, A. S., Garcia-Perez, A. Burg, M. B., and Handler, J. S. (1992) J. Biol. Chem. 267, 6297-6301
14. Borden, L. A. (1996) Neurochem. Int. 29, 335-356
15. Liu, Q.-R., Lopez-Corcuera, B., Mandiyan, S., Nelson, H., and Nelson, N. (1993) J. Biol. Chem. 268, 2106-2112
16. Borden, L. A., Smith, K. E., Hartig, P. R., Branchek, T. A., and Weinshank, R. L. (1992) J. Biol. Chem. 267, 21098-21104
17. Liu Q. R., Mandiyan S., Nelson H., and Nelson N. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 6639-6643
18. Guastella, J., Nelson, N., Nelson, H., Czyzyk, L., Keynan, S., Miedel, M. C., Davidson, N., Lester, H. A., and Kanner, B. I. (1990) Science 249, 1303-1306
19. Kavanaugh, M. P., Arriza, J. L., North, E. A., and Amara, S. G. (1992) J. Biol. Chem. 267, 22007-22009
20. Mager, S., Naeve, J., Quick, M., Labarca, C., Davidson, N., and Lester, H. A. (1993). Neuron 10, 177-188
21. Cammack, J. N. (1994) Neuron 13, 949-960
22. Cammack, J. N., and Schwartz, E. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 723-727
23. Risso, S., DeFelcie, L. J., and Blakely, R. D. (1996) J. Physiol. (Lond.) 490, 691-702
24. Su, A., Mager, S., Mayo, S. L., and Lester, H. A. (1996) Biophys. J. 70, 762-777
25. Lester, H. A., Mager, S., Quick, M. W., and Corey, J. L. (1994) Annu. Rev. Pharmacol. Toxicol. 34, 219-249
26. Sonders, M. S., and Amara S. G. (1996) Curr. Opin. Neurobiol. 6, 294-302
27. Busch, A. E., Kopp, H.-G., Waldegger, S., Samarzija, I., Suessbrich, H., Raber, G., Kunzelmann, K., Ruppersberg, J. P., and Lang, F. (1996) J. Physiol. (Lond.) 491, 735-741
28. Peng, H. B. (1991) Methods Cell Biol. 36, 657-662
29. Quick, M. W., Corey, J. L., Davidson, N., and Lester, H. A. (1997) J. Neurosci. 17, 2967-2979
30. Stein, W. D. (1986) Academic Press, Orlando, FL