Presence of γ-aminobutyric acid transporter mRNA in interneurons and principal cells of rat hippocampus

Neuroscience Letters

Volumn 288, Issue 3, 2000, Pages 175-178

  Frahm, Christiane ^a   Engel, Dominique ^a   Piechotta, Antje ^a   Heinemann, Uwe ^a   Draguhn, Andreas ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Aminobutyric acid uptake; Glutamate dehydrogenase; Hippocampus; In situ hybridization; Inhibition; Interneurons

Indexed keywords

GLUTAMATE DEHYDROGENASE; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; FEMALE; HIPPOCAMPUS; IN SITU HYBRIDIZATION; INTERNEURON; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CARRIER PROTEINS; FEMALE; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; IN SITU HYBRIDIZATION; INTERNEURONS; MALE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; ORGANIC ANION TRANSPORTERS; PLASMA MEMBRANE NEUROTRANSMITTER TRANSPORT PROTEINS; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 0034698496     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01217-9     Document Type: Article

References (20)

1. Cammack J.N., Rakhilin S.V., Schwartz E.A. A GABA transporter operates asymmetrically and with variable stoichiometry. Neuron. 13:1994;949-960.
2. Cao Y., Wolcox K.S., Martin C.E., Rchinsky T.L., Eberwine J., Dichter M.A. Presence of mRNA for glutamate decarboxylase in both excitatory and inhibitory neurons. Proc. Natl. Acad. Sci. USA. 93:1996;9844-9849.
3. Dingledine R., Korn S.J. Gamma-aminobutyric acid uptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice. J. Physiol. (Lond.). 366:1985;387-409.
4. Draguhn A., Heinemann U. Different mechanisms regulate IPSC kinetics in early postnatal and juvenile hippocampal granule cells. J. Neurophysiol. 76:1996;3983-3993.
5. Durkin M.M., Smith K.E., Borden L.A., Weinshank R.L., Branchek T.A., Gustafson E.L. Localization of mRNAs encoding three GABA transporters in rat brain: an in situ hybridization study. Mol. Brain Res. 33:1995;7-21.
6. Engel D., Schmitz D., Gloveli T., Frahm C., Heinemann U., Draguhn A. Laminar difference in GABA uptake and GAT-1 expression in rat CA1. J. Physiol. (Lond.). 512:1998;643-649.
7. Erlander M.G., Tillakaratne N.J.K., Feldblum S., Patel N., Tobin A.J. Two genes encode distinct glutamate decarboxylase. Neuron. 7:1991;91-100.
8. Guastella J., Nelson N., Nelson H., Czyzyk L., Keynan S., Miedel M.C., Davidson N., Lester H., Kanner B. Cloning and expression of a rat brain GABA transporter. Science. 249:1990;1303-1306.
9. Houser C.R., Esclapez M. Localization of mRNAs encoding two forms of glutamic acid decarboxylase in the rat hippocampal formation. Hippocampus. 4:1994;530-545.
10. Krogsgaard-Larsen P., Falch E., Larsson O.M., Schousboe A. GABA uptake inhibitors: relevance to antiepileptic drug research. Epilepsy Res. 1:1987;77-93.
11. Liu Q.R., Lopez-Corcuera B., Mandiyan S., Nelson H., Nelson N. Molecular characterization of four pharmacologically distinct γ-aminobutyric acid transporters in mouse brain. J. Biol. Chem. 268:1993;2106-2112.
12. Michelsen B.K., Petersen J.S., Boel E., Moldrup A., Dyrberg T., Madsen O.D. Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA. 88:1991;8754-8758.
13. Rattray M., Priestley J.V. Differential expression of GABA transporter-1 messenger RNA in subpopulations of GABA neurones. Neurosci. Lett. 156:1993;163-166.
14. Ribak C.E., Tong W., Brecha N.C. The GABA plasma membrane transporters GAT-1 and GAT-3, display different distributions in the rat hippocampus. J. Comp. Neurol. 367:1996;595-606.
15. Schousboe A., Larsson O.M., Wood J.D., Krogsgaard-Larsen P. Transport and metabolism of γ-aminobutyric acid in neurons and glia: implications for epilepsy. Epilepsia. 24:1983;531-538.
16. Schwarzer C., Sperk G. Hippocampal granule cells express glutamic acid decarboxylase-67 after limbic seizures in the rat. Neuroscience. 69:1995;705-709.
17. Sloviter R.S., Dichter M.A., Rachinsky T.L., Dean E., Goodman J.H., Sollas A.L., Martin D.L. Basal expression and induction of glutamate decarboxylase and GABA in excitatory granule cells of the rat and monkey hippocampal dentate gyrus. J. Comp. Neurol. 373:1996;593-618.
18. Swan M., Najlerahim A., Watson R.E.B., Bennett J.P. Distribution of mRNA for the GABA transporter GAT-1 in the rat brain: evidence that GABA uptake is not limited to presynaptic neurons. J. Anat. 185:1994;315-323.
19. Takahashi M., Sarantis M., Attwell D. Postsynaptic glutamate uptake in rat cerebellar Purkinje cells. J. Physiol. (Lond.). 497:1996;523-530.
20. 67) mRNA localization. Mol. Brain Res. 44:1997;205-218.