Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity

European Journal of Pharmacology

Volumn 375, Issue 1-3, 1999, Pages 367-374

  Bolvig, Tina ^a   Larsson, Orla M ^a   Pickering, Darryl S ^a   Nelson, Nathan ^c   Falch, Erik ^b   Krogsgaard Larsen, Povl ^b   Schousboe, Arne ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Anticonvulsant; DPB (4,4 diphenyl 3 butenyl) THPO; DPB THAO; Epilepsy; GABA ( Aminobutyric acid) transporter; GABA uptake inhibitor; THAO (5,6,7,8 tetrahydro 4H isoxazolo 4,5 c azepin 3 ol); THPO (4,5,6,7 tetrahydroisoxazolo 4,5 c pyridin 3 ol)

Indexed keywords

4 AMINOBUTYRIC ACID DERIVATIVE; 4,5,6,7 TETRAHYDROISOXAZOLO[4,5 C]PYRIDIN 3 OL; ANTICONVULSIVE AGENT; ISOXAZOLE DERIVATIVE; TIAGABINE;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL CELL; ANTICONVULSANT ACTIVITY; ARTICLE; ASTROCYTE; BRAIN CORTEX; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; EPILEPSY; HUMAN; HUMAN CELL; KIDNEY CELL; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ANIMALS; ANIMALS, NEWBORN; ANTICONVULSANTS; ASTROCYTES; CELLS, CULTURED; EMBRYO; GAMMA-AMINOBUTYRIC ACID; HUMANS; KIDNEY; MICE; NEURONS; SEIZURES;

EID: 0032980011     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00263-0     Document Type: Article

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