IL-4 and IL-13 expression in chronic sinusitis: Relationship with cellular infiltrate and effect of topical corticosteroid treatment

Journal of Otolaryngology

Volumn 26, Issue 3, 1997, Pages 160-165

  Ghamdi, Khalid Al ^a,c   Ghaffar, Omar ^a   Small, Peter ^b   Frenkiel, Saul ^b   Hamid, Qutayba ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Eosinophils; Interleukin 13 (IL 13); Interleukin 4 (IL 4); Sinusitis; Steroid

Indexed keywords

FLUTICASONE PROPIONATE; INTERLEUKIN 13; INTERLEUKIN 4; MESSENGER RNA;

ADULT; AGED; ALLERGY; ARTICLE; CELL INFILTRATION; CHRONIC SINUSITIS; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; EOSINOPHIL; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; PRICK TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; TOPICAL DRUG ADMINISTRATION;

ADOLESCENT; ADULT; AGED; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD3; ANTIGENS, CD8; CHRONIC DISEASE; EOSINOPHILS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERLEUKIN-13; INTERLEUKIN-4; MALE; MIDDLE AGED; RHINITIS, ALLERGIC, PERENNIAL; RNA, MESSENGER; SINUSITIS; STEROIDS; T-LYMPHOCYTES;

EID: 0030877164     PISSN: 03816605     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Gliklich RE, Metson R. The health impact of chronic sinusitis in patients seeking otolaryngologic care. Otolaryngol Head Neck Surg 1995; 113:104-109.
2. Van Nostrand AWP, Goodman WS. Pathologic aspects of mucosal lesions of the maxillary sinus. Otolaryngol Clin North Am 1976; 9:21-27.
3. Varney V, Jacobson M, Sudderick R, et al. Immunohistology of the nasal mucosa following allergen-induced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils. Am Rev Respir Dis 1992; 145:170-175.
4. Wardlaw AJ, Dunnettes S, Gleich GJ, et al. Eosinophils and mast cells in bronchoalveolar lavage in mild asthma. Relationship to bronchial hyper-reactivity. Am Rev Respir Dis 1988; 137:62-69.
5. Harlin SL, Lane SR, Myers J, et al. A clinical and pathologic study of chronic sinusitis: the role of the eosinophil. J Allergy Clin Immunol 1988; 81:867-875.
6. Hamilos D, Leung D, Wood R, et al. Evidence for distinct cytokine expression in allergic vs. nonallergic chronic sinusitis. J Allergy Clin Immunol 1995; 96:537-544.
7. Schleimer R, Sterbinsky S, Kaiser J, et al. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium: association with expression of VCAM-1. J Immunol 1992; 148:1086-1092.
8. Durham D, Ying S, Varney V, et al. Cytokine mRNA expression for IL-3, IL-4, IL-5, and GM-CSF in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia. J Immunol 1992; 148:2390-2394.
9. Masuyama K, Jacobson M, Rak S, et al. Topical corticosteroid (fluticasone propionate) inhibits cell expressing cytokine mRNA for IL-4 in the nasal mucosa in allergen-induced rhinitis. J Immunol 1994; 151:192-199.
10. Zurawski G, de Vries J. IL-13, and IL-4 like cytokine that acts on monocytes and B cells, but not on T cells. Immunol Today 1994; 15:19-26.
11. Bochner B, Klunk D, Sterbinsky S, et al. IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J Immunol 1995; 154:799-803.
12. Punnonen J, Aversa G, Benjamin G, et al. IL-13 induces IL-4 independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci U S A 1993; 90:3730-3734.
13. Frew AJ, Kay AB. The relationship between infiltrating CD4 lymphocytes, activated eosinophils and the magnitude of the allergen-induced late phase cutaneous reaction in man. J Immunol 1988; 141:4158-4164.
14. Hamid Q, Wharton J, Terenghi G, et al. Localization of atrial natriuretic peptide mRNA and immunoreactivity in rat heart and human atrial appendage. Proc Natl Acad Sci USA 1987; 84:6760-6764.
15. Frenkiel S. The surgical management of chronic rhinitis and sinusitis. Pract Allergy Immunol 1993; 8:160-164.
16. Hamilos D, Leung D, Wood R, et al. Chronic hyperplastic sinusitis: Association of tissue eosinophilia with mRNA expression of granulocyte-macrophage colony-stimulating factor and interleukin-3. J Allergy Clin Immunol 1993; 92: 39-48.
17. Walker C, Bode E, Boer L, et al. Allergic and nonallergic asthmatics have different pattern of T cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis 1992; 146:109-115.
18. Minty A, Chalon P, Derocq J, et al. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 1993; 362:248-250.
19. Mosman T, Cherwinski H, Bond M, et al. Two types of murine helper T cell clone. 1. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-2357.
20. Celis E, Miller RW, Wiktor TJ, et al. Isolation and characterization of human T cell lines and clones reactive to rabies virus: antigen specificity and production of interferon-gamma. J Immunol 1986; 136:692-697.
21. Durham S, Gould H, Jacobson M, et al. Local control of ε-gene expression in B cells of the nasal mucosa in hay fever patients following allergen-challenge (abstract). J Allergy Clin Immunol 1996; 97:460.