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Volumn 4, Issue 10, 2003, Pages 1637-1641

Spinocerebellar degeneration

Author keywords

Animal models; Antioxidants; Biomarkers; Rating scales; Spinocerebellar

Indexed keywords

3,4 DIAMINOPYRIDINE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; ACETAZOLAMIDE; ACETYLCYSTEINE; ALPHA TOCOPHEROL; AMANTADINE; BACLOFEN; BENZODIAZEPINE DERIVATIVE; BIOLOGICAL MARKER; BUSPIRONE; CARBONATE DEHYDRATASE INHIBITOR; CARNITINE; CLONAZEPAM; CREATININE; GABAPENTIN; ICOSAPENTAENOIC ACID ETHYL ESTER; IDEBENONE; NEUROTRANSMITTER; POTASSIUM CHANNEL BLOCKING AGENT; PROTIRELIN; RIBOFLAVIN; SCAVENGER; SELENIUM; SEROTONIN 1A AGONIST; SOMATOMEDIN C; TALTIRELIN; THIOCTIC ACID; UBIDECARENONE; UNINDEXED DRUG;

EID: 0142179179     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.4.10.1637     Document Type: Editorial
Times cited : (5)

References (58)
  • 2
    • 0142143796 scopus 로고    scopus 로고
    • Inherited cerebellar ataxias
    • Johnson RT, Griffin JW, McArthur JC (Eds), Mosby, St. Louis, USA
    • GOMEZ C: Inherited cerebellar ataxias. In: Current Therapy in Neurological Disease. Johnson RT, Griffin JW, McArthur JC (Eds), Mosby, St. Louis, USA (2001).
    • (2001) Current Therapy in Neurological Disease
    • Gomez, C.1
  • 3
    • 84902404999 scopus 로고    scopus 로고
    • Diagnostic evaluation of ataxic patients
    • Pulst SM (Ed.), Academic Press, San Diego, USA
    • PERLMAN SL: Diagnostic evaluation of ataxic patients. In: Genetics of Movement Disorders. Pulst SM (Ed.), Academic Press, San Diego, USA (2003).
    • (2003) Genetics of Movement Disorders
    • Perlman, S.L.1
  • 4
    • 0036098482 scopus 로고    scopus 로고
    • Friedreich ataxia: Effects of generic understanding on clinical evaluation and therapy
    • LYNCH DR, FARMER JM, BALCER LJ, WILSON RB: Friedreich ataxia: effects of generic understanding on clinical evaluation and therapy. Arch. Neurol. (2002) 59:743-747.
    • (2002) Arch. Neurol. , vol.59 , pp. 743-747
    • Lynch, D.R.1    Farmer, J.M.2    Balcer, L.J.3    Wilson, R.B.4
  • 5
    • 0037077040 scopus 로고    scopus 로고
    • Toxic proteins in neurodegenerative disease
    • TAYLOR JP, HARDY J, FISCHBECK KH: Toxic proteins in neurodegenerative disease. Science (2002) 296:1991-1995.
    • (2002) Science , vol.296 , pp. 1991-1995
    • Taylor, J.P.1    Hardy, J.2    Fischbeck, K.H.3
  • 6
    • 0036591663 scopus 로고    scopus 로고
    • Dominantly inherited, non-coding microsatellite expansion disorders
    • RANUM LP, DAY JW: Dominantly inherited, non-coding microsatellite expansion disorders. Curr. Opin. Genet. Dev. (2002) 12:266-271.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 266-271
    • Ranum, L.P.1    Day, J.W.2
  • 7
    • 0029163222 scopus 로고
    • SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat
    • BURRIGHT EN, CLARK HB, SERVADIO A et al.: SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat. Cell (1995) 82:937-948.
    • (1995) Cell , vol.82 , pp. 937-948
    • Burright, E.N.1    Clark, H.B.2    Servadio, A.3
  • 8
    • 0033811788 scopus 로고    scopus 로고
    • Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human
    • HUYNH DP, FIGUEROA K, HOANG N, PULST SM: Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human. Nat. Genet. (2000) 26:44-50.
    • (2000) Nat. Genet. , vol.26 , pp. 44-50
    • Huynh, D.P.1    Figueroa, K.2    Hoang, N.3    Pulst, S.M.4
  • 9
    • 0036566229 scopus 로고    scopus 로고
    • YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit
    • CEMAL CK, CARROLL CJ, LAWRENCE L et al.: YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit. Hum. Mol. Genet. (2002) 11:1075-1094.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1075-1094
    • Cemal, C.K.1    Carroll, C.J.2    Lawrence, L.3
  • 10
    • 0034641891 scopus 로고    scopus 로고
    • Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice
    • YVERT G, LINDENBERG KS, PICAUD S, LANDWEHRMEYER GB, SAHEL JA, MANDEL JL: Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice. Hum. Mol. Genet. (2000) 9:2491-2506.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2491-2506
    • Yvert, G.1    Lindenberg, K.S.2    Picaud, S.3    Landwehrmeyer, G.B.4    Sahel, J.A.5    Mandel, J.L.6
  • 11
    • 0032907359 scopus 로고    scopus 로고
    • Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients
    • SATO T, OYAKE M, NAKAMURA K et al.: Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients. Hum. Mol. Genet. (1999) 8:99-106.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 99-106
    • Sato, T.1    Oyake, M.2    Nakamura, K.3
  • 13
    • 0029937595 scopus 로고    scopus 로고
    • The insulin-like growth Factor I system in cerebellar degeneration
    • TORRES-ALEMAN I, BARRIOS V, LLEDO A, BERCIANO J: The insulin-like growth Factor I system in cerebellar degeneration. Ann. Neurol. (1996) 39:335-342.
    • (1996) Ann. Neurol. , vol.39 , pp. 335-342
    • Torres-Aleman, I.1    Barrios, V.2    Lledo, A.3    Berciano, J.4
  • 14
    • 0035780208 scopus 로고    scopus 로고
    • Glutathione in blood of patients with Friedreich's ataxia
    • PIEMONTE F, PASTORE A, TOZZI G et al.: Glutathione in blood of patients with Friedreich's ataxia. Eur. J. Clin. Invest. (2001) 31:1007-1011.
    • (2001) Eur. J. Clin. Invest. , vol.31 , pp. 1007-1011
    • Piemonte, F.1    Pastore, A.2    Tozzi, G.3
  • 15
    • 0034642203 scopus 로고    scopus 로고
    • Oxidative stress in patients with Friedreich ataxia
    • SCHULZ JB, DEHMER T, SCHOLS L et al.: Oxidative stress in patients with Friedreich ataxia. Neurology (2000) 55:1719-1721.
    • (2000) Neurology , vol.55 , pp. 1719-1721
    • Schulz, J.B.1    Dehmer, T.2    Schols, L.3
  • 16
    • 0030939011 scopus 로고    scopus 로고
    • International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. The Ataxia Neuropharmacology Committee of the World Federation of Neurology
    • TROUILLAS P, TAKAYANAGI T, HALLETT M et al.: International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. The Ataxia Neuropharmacology Committee of the World Federation of Neurology. J. Neurol. Sci. (1997) 145:205-211.
    • (1997) J. Neurol. Sci. , vol.145 , pp. 205-211
    • Trouillas, P.1    Takayanagi, T.2    Hallett, M.3
  • 18
    • 0034636062 scopus 로고    scopus 로고
    • Quantitative neurological assessment of ataxia-telangiectasia
    • CRAWFORD TO, MANDIR AS, LEFTON-GREIF MA et al.: Quantitative neurological assessment of ataxia-telangiectasia. Neurology (2000) 54:1505-1509.
    • (2000) Neurology , vol.54 , pp. 1505-1509
    • Crawford, T.O.1    Mandir, A.S.2    Lefton-Greif, M.A.3
  • 19
    • 0142174637 scopus 로고
    • Neurotransmitters in the cerebellum. Scientific aspects and clinical relevance
    • Harding AE, Deufel T (Eds), Raven Press, New York, USA
    • OERTEL WH: Neurotransmitters in the cerebellum. Scientific aspects and clinical relevance. In: Inherited Ataxias. Harding AE, Deufel T (Eds), Raven Press, New York, USA (1993).
    • (1993) Inherited Ataxias
    • Oertel, W.H.1
  • 20
    • 4243285373 scopus 로고    scopus 로고
    • Improvement of ataxic signs in cortical cerebellar atrophy with the GABAergic drug gabapentin
    • GAZULLA JE JM, BENAVENTE I, TORDESILLAS C: Improvement of ataxic signs in cortical cerebellar atrophy with the GABAergic drug gabapentin. Neurology (2003) 60:A472.
    • (2003) Neurology , vol.60
    • Gazulla, J.E.1    Gazulla, J.M.2    Benavente, I.3    Tordesillas, C.4
  • 21
    • 0030715601 scopus 로고    scopus 로고
    • Efficacy of TRH-T for spinocerebellar degeneration - The relation between clinical features and effect of TRH therapy
    • WARAGAI M, OGAWARA K, TAKAYA Y, HAYASHI M: [Efficacy of TRH-T for spinocerebellar degeneration - the relation between clinical features and effect of TRH therapy]. Rinsho Shinkeigaku (1997) 37:587-594.
    • (1997) Rinsho Shinkeigaku , vol.37 , pp. 587-594
    • Waragai, M.1    Ogawara, K.2    Takaya, Y.3    Hayashi, M.4
  • 24
    • 0038119445 scopus 로고    scopus 로고
    • Treatment of downbeat nystagmus with 3,4-diaminopyridine: A placebo-controlled study
    • STRUPP M, SCHULER O, KRAFCZYK S et al.: Treatment of downbeat nystagmus with 3,4-diaminopyridine: a placebo-controlled study. Neurology (2003) 61:165-170.
    • (2003) Neurology , vol.61 , pp. 165-170
    • Strupp, M.1    Schuler, O.2    Krafczyk, S.3
  • 25
    • 0142236696 scopus 로고    scopus 로고
    • Mechanism of action of acetazolamide in treatment of episodic ataxia Type 2
    • WAN J, BALOH RW, JEN JC: Mechanism of action of acetazolamide in treatment of episodic ataxia Type 2. Neurology (2003) 60:A330.
    • (2003) Neurology , vol.60
    • Wan, J.1    Baloh, R.W.2    Jen, J.C.3
  • 26
    • 0031726082 scopus 로고    scopus 로고
    • Spinocerebellar ataxia Type 6 with positional vertigo and acetazolamide responsive episodic ataxia
    • JEN JC, YUE Q, KARRIM J, NELSON SF, BALOH RW: Spinocerebellar ataxia Type 6 with positional vertigo and acetazolamide responsive episodic ataxia. J. Neurol. Neurosurg. Psychiatry (1998) 65:565-568.
    • (1998) J. Neurol. Neurosurg. Psychiatry , vol.65 , pp. 565-568
    • Jen, J.C.1    Yue, Q.2    Karrim, J.3    Nelson, S.F.4    Baloh, R.W.5
  • 27
    • 0034960740 scopus 로고    scopus 로고
    • Clinical trial of acetazolamide in SCA6, with assessment using the Ataxia Rating Scale and body stabilometry
    • YABE I, SASAKI H, YAMASHITA I, TAKEI A, TASHIRO K: Clinical trial of acetazolamide in SCA6, with assessment using the Ataxia Rating Scale and body stabilometry. Acta Neurol. Scand. (2001) 104:44-47.
    • (2001) Acta Neurol. Scand. , vol.104 , pp. 44-47
    • Yabe, I.1    Sasaki, H.2    Yamashita, I.3    Takei, A.4    Tashiro, K.5
  • 28
    • 0036372896 scopus 로고    scopus 로고
    • Genetics of episodic ataxia
    • JEN JC, BALOH RW: Genetics of episodic ataxia. Adv. Neurol. (2002) 89:459-461.
    • (2002) Adv. Neurol. , vol.89 , pp. 459-461
    • Jen, J.C.1    Baloh, R.W.2
  • 29
    • 0030066723 scopus 로고    scopus 로고
    • Grafted cerebellar cells in a mouse model of hereditary ataxia express IGF-I system genes and partially restore behavioral function
    • ZHANG W, LEE WH, TRIARHOU LC: Grafted cerebellar cells in a mouse model of hereditary ataxia express IGF-I system genes and partially restore behavioral function. Nat. Med. (1996) 2:65-71.
    • (1996) Nat. Med. , vol.2 , pp. 65-71
    • Zhang, W.1    Lee, W.H.2    Triarhou, L.C.3
  • 30
    • 0032854754 scopus 로고    scopus 로고
    • Cerebellar allografts survive and transiently alleviate ataxia in a transgenic model of spinocerebellar ataxia type-1
    • KAEMMERER WF, LOW WC: Cerebellar allografts survive and transiently alleviate ataxia in a transgenic model of spinocerebellar ataxia type-1. Exp. Neurol. (1999) 158:301-311.
    • (1999) Exp. Neurol. , vol.158 , pp. 301-311
    • Kaemmerer, W.F.1    Low, W.C.2
  • 31
    • 0033046355 scopus 로고    scopus 로고
    • Neuroprotective actions of peripherally administered insulin-like growth Factor I in the injured olivo-cerebellar pathway
    • FERNANDEZ AM, GONZALEZ DE LA VEGA AG, PLANAS B, TORRES-ALEMAN I: Neuroprotective actions of peripherally administered insulin-like growth Factor I in the injured olivo-cerebellar pathway Eur. J. Neurosci. (1999) 11:2019-2030.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2019-2030
    • Fernandez, A.M.1    Gonzalez Dela Vega, A.G.2    Planas, B.3    Torres-Aleman, I.4
  • 32
    • 0037314215 scopus 로고    scopus 로고
    • Neuronal degeneration and mitochondrial dysfunction
    • SCHON EA, MANFREDI G: Neuronal degeneration and mitochondrial dysfunction. J. Clin. Invest. (2003) 111:303-312.
    • (2003) J. Clin. Invest. , vol.111 , pp. 303-312
    • Schon, E.A.1    Manfredi, G.2
  • 33
    • 0043180531 scopus 로고    scopus 로고
    • Excitotoxic and excitoprotective mechanisms: Abundant targets for the prevention and treatment of neurodegenerative disorders
    • MATTSON MP: Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromolecular Med. (2003) 3:65-94.
    • (2003) Neuromolecular Med. , vol.3 , pp. 65-94
    • Mattson, M.P.1
  • 34
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • FRIEDLANDER RM: Apoptosis and caspases in neurodegenerative diseases. N. Engl. J. Med. (2003) 348:1365-1375.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 35
    • 0037398112 scopus 로고    scopus 로고
    • The use of antioxidants in Friedreich's ataxia treatment
    • 569-275
    • RUSTIN P: The use of antioxidants in Friedreich's ataxia treatment. Expert Opin. Investig. Drugs (2003) 12:569-275.
    • (2003) Expert Opin. Investig. Drugs , vol.12
    • Rustin, P.1
  • 38
    • 0036221156 scopus 로고    scopus 로고
    • Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia
    • HAUSSE AO, AGGOUN Y, BONNET D et al.: Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia. Heart (2002) 87:346-349.
    • (2002) Heart , vol.87 , pp. 346-349
    • Hausse, A.O.1    Aggoun, Y.2    Bonnet, D.3
  • 39
    • 0038187688 scopus 로고    scopus 로고
    • Idebenone treatment in Friedreich's ataxia: Neurological, cardiac, and biochemical monitoring
    • BUYSE G, MERTENS L, DI SALVO G et al.: Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring. Neurology (2003) 60:1679-1681.
    • (2003) Neurology , vol.60 , pp. 1679-1681
    • Buyse, G.1    Mertens, L.2    Di Salvo, G.3
  • 40
    • 0037849955 scopus 로고    scopus 로고
    • Idebenone treatment in Friedreich patients: One-year-long randomized placebo-controlled trial
    • MARIOTTI C, SOLARI A, TORTA D, MARANO I, FIORENTINI C, DI DONATO S: Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial. Neurology (2003) 60:1676-1679.
    • (2003) Neurology , vol.60 , pp. 1676-1679
    • Mariotti, C.1    Solari, A.2    Torta, D.3    Marano, I.4    Fiorentini, C.5    Di Donato, S.6
  • 41
    • 0036237241 scopus 로고    scopus 로고
    • Prevention of mitochondrial oxidative damage using targeted antioxidants
    • KELSO GF, PORTEOUS CM, HUGHES G et al.: Prevention of mitochondrial oxidative damage using targeted antioxidants. Ann. NY Acad. Sci. (2002) 959:263-274.
    • (2002) Ann. NY Acad. Sci. , vol.959 , pp. 263-274
    • Kelso, G.F.1    Porteous, C.M.2    Hughes, G.3
  • 42
    • 0037317490 scopus 로고    scopus 로고
    • Friedreich's ataxia: Iron chelators that target the mitochondrion as a therapeutic strategy?
    • RICHARDSON DR: Friedreich's ataxia: iron chelators that target the mitochondrion as a therapeutic strategy?. Expert Opin. Investig. Drugs (2003) 12:235-245.
    • (2003) Expert Opin. Investig. Drugs , vol.12 , pp. 235-245
    • Richardson, D.R.1
  • 43
    • 0035925748 scopus 로고    scopus 로고
    • Creatine-supplemented diet extends Purkinje cell survival in spinocerebellar ataxia Type 1 transgenic mice but does not prevent the ataxic phenotype
    • KAEMMERER WF, RODRIGUES CM, STEER CJ, LOW WC: Creatine-supplemented diet extends Purkinje cell survival in spinocerebellar ataxia Type 1 transgenic mice but does not prevent the ataxic phenotype. Neuroscience (2001) 103:713-724.
    • (2001) Neuroscience , vol.103 , pp. 713-724
    • Kaemmerer, W.F.1    Rodrigues, C.M.2    Steer, C.J.3    Low, W.C.4
  • 44
    • 0028856571 scopus 로고
    • Trial of d-alpha-tocopherol in Huntington's disease
    • PEYSER CE, FOLSTEIN M, CHASE GA et al.: Trial of d-alpha-tocopherol in Huntington's disease. Am. J. Psychiatry (1995) 152:1771-1775.
    • (1995) Am. J. Psychiatry , vol.152 , pp. 1771-1775
    • Peyser, C.E.1    Folstein, M.2    Chase, G.A.3
  • 45
    • 85009226418 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease
    • GROUP HS: A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology (2001) 57:397-404.
    • (2001) Neurology , vol.57 , pp. 397-404
    • Group, H.S.1
  • 46
    • 0037677341 scopus 로고    scopus 로고
    • Creatine therapy for Huntington's disease: Clinical and MRS findings in a 1-year pilot study
    • TABRIZI SJ, BLAMIRE AM, MANNERS DN et al.: Creatine therapy for Huntington's disease: clinical and MRS findings in a 1-year pilot study. Neurology (2003) 61:141-142.
    • (2003) Neurology , vol.61 , pp. 141-142
    • Tabrizi, S.J.1    Blamire, A.M.2    Manners, D.N.3
  • 47
    • 0036725642 scopus 로고    scopus 로고
    • Effect of vitamin E (DL-alpha-tocopherol) on the frequency of chromosomal damage in lymphocytes from patients with ataxia telangiectasia
    • MARCELAIN K, NAVARRETE CL, BRAVO M, SANTOS M, BE C, PINCHEIRA J: [Effect of vitamin E (DL-alpha-tocopherol) on the frequency of chromosomal damage in lymphocytes from patients with ataxia telangiectasia]. Rev. Med. Chil. (2002) 130:957-963.
    • (2002) Rev. Med. Chil. , vol.130 , pp. 957-963
    • Marcelain, K.1    Navarrete, C.L.2    Bravo, M.3    Santos, M.4    Be, C.5    Pincheira, J.6
  • 48
    • 0035905742 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: Chronic activation of damage-responsive functions is reduced by alpha-lipoic acid
    • GATEI M, SHKEDY D, KHANNA KK et al.: Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by alpha-lipoic acid. Oncogene (2001) 20:289-294.
    • (2001) Oncogene , vol.20 , pp. 289-294
    • Gatei, M.1    Shkedy, D.2    Khanna, K.K.3
  • 49
    • 0034796483 scopus 로고    scopus 로고
    • Riluzole in Huntington's disease (HD): An open label study with one year follow up
    • SEPPI K, MUELLER J, BODNER T et al.: Riluzole in Huntington's disease (HD): an open label study with one year follow up. J. Neurol. (2001) 248:866-869.
    • (2001) J. Neurol. , vol.248 , pp. 866-869
    • Seppi, K.1    Mueller, J.2    Bodner, T.3
  • 51
    • 0037398420 scopus 로고    scopus 로고
    • Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases
    • STEFFAN JS, THOMPSON LM: Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases. Expert Opin. Ther. Targets (2003) 7:201-213.
    • (2003) Expert Opin. Ther. Targets , vol.7 , pp. 201-213
    • Steffan, J.S.1    Thompson, L.M.2
  • 52
    • 12244265476 scopus 로고    scopus 로고
    • Minocycline for Huntington's disease: An open label study
    • BONELLI RM, HEUBERGER C, REISECKER F: Minocycline for Huntington's disease: an open label study. Neurology (2003) 60:883-884.
    • (2003) Neurology , vol.60 , pp. 883-884
    • Bonelli, R.M.1    Heuberger, C.2    Reisecker, F.3
  • 53
    • 0042845880 scopus 로고    scopus 로고
    • Minocycline and doxycycline are not beneficial in a model of Huntington's disease
    • SMITH DL, WOODMAN B, MAHAL A et al.: Minocycline and doxycycline are not beneficial in a model of Huntington's disease. Ann. Neurol. (2003) 54:186-196.
    • (2003) Ann. Neurol. , vol.54 , pp. 186-196
    • Smith, D.L.1    Woodman, B.2    Mahal, A.3
  • 54
    • 0035394668 scopus 로고    scopus 로고
    • Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
    • CUMMINGS CJ, SUN Y, OPAL P et al.: Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum. Mol. Genet. (2001) 10:1511-1518.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1511-1518
    • Cummings, C.J.1    Sun, Y.2    Opal, P.3
  • 55
    • 0036073289 scopus 로고    scopus 로고
    • Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch
    • YOSHIDA H, YOSHIZAWA T, SHIBASAKI F, SHOJI S, KANAZAWA I: Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch. Neurobiol. Dis. (2002) 10:88-99.
    • (2002) Neurobiol. Dis. , vol.10 , pp. 88-99
    • Yoshida, H.1    Yoshizawa, T.2    Shibasaki, F.3    Shoji, S.4    Kanazawa, I.5
  • 56
    • 0035909330 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
    • STEFFAN JS, BODAI L, PALLOS J et al.: Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature (2001) 413:739-743.
    • (2001) Nature , vol.413 , pp. 739-743
    • Steffan, J.S.1    Bodai, L.2    Pallos, J.3
  • 57
    • 0037452775 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
    • HOCKLY E, RICHON VM, WOODMAN B et al.: Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proc. Natl. Acad. Sci. USA (2003) 100:2041-2046.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2041-2046
    • Hockly, E.1    Richon, V.M.2    Woodman, B.3
  • 58
    • 0038132996 scopus 로고    scopus 로고
    • Allele-specific silencing of dominant disease genes
    • MILLER VM, XIA H, MARRS GL et al.: Allele-specific silencing of dominant disease genes. Proc. Natl. Acad. Sci. USA (2003) 100:7195-7200.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7195-7200
    • Miller, V.M.1    Xia, H.2    Marrs, G.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.