메뉴 건너뛰기




Volumn 10, Issue 4, 2003, Pages 797-802

Hypoxia-inducible factor-1α expression and angiogenesis in gastrointestinal stromal tumor of the stomach

Author keywords

GIST; HIF 1 ; MVD; Prognosis; VEGF

Indexed keywords

HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; TRANSCRIPTION FACTOR; VASCULOTROPIN A;

EID: 0142175222     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.10.4.797     Document Type: Article
Times cited : (78)

References (46)
  • 1
    • 0022648938 scopus 로고
    • How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes Memorial Award Lecture
    • Folkman J: How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes Memorial Award Lecture. Cancer Res 46: 467-473, 1986.
    • (1986) Cancer Res , vol.46 , pp. 467-473
    • Folkman, J.1
  • 2
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J and Shing Y: Angiogenesis. J Biol Chem 267: 10931-10934, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 3
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • DOI 10.1210/er.18.1.4
    • Ferrara N and Davis-Smyth T: The biology of vascular endothelial growth factor. Endocr Rev 18: 4-25, 1997. (Pubitemid 27076453)
    • (1997) Endocrine Reviews , vol.18 , Issue.1 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 4
    • 0028842903 scopus 로고
    • Role of VEGF-FLT receptor system in normal and tumor angiogenesis
    • Shibuya M: Role of VEGF-FLT receptor system in normal and tumor angiogenesis. Adv Cancer Res 67: 281-316, 1995.
    • (1995) Adv Cancer Res , vol.67 , pp. 281-316
    • Shibuya, M.1
  • 5
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
    • Dvorak HF, Brown LF, Detmar M and Dvorak AM: Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 146: 1029-1039, 1995.
    • (1995) Am J Pathol , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    Dvorak, A.M.4
  • 6
    • 0030265393 scopus 로고
    • Vascular endothelial growth factor and its receptors
    • Klagsbrun M and D'Amore PA: Vascular endothelial growth factor and its receptors. Cytokine Growth Factor Rev 7: 259-270, 1995.
    • (1995) Cytokine Growth Factor Rev , vol.7 , pp. 259-270
    • Klagsbrun, M.1    D'Amore, P.A.2
  • 7
    • 84880449850 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach
    • In press
    • Takahashi R, Tanaka S, Kitadai Y, Sumii M, Yoshihara M, Haruma K and Chayama K: Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach. Oncology 2002 (In press).
    • (2002) Oncology
    • Takahashi, R.1    Tanaka, S.2    Kitadai, Y.3    Sumii, M.4    Yoshihara, M.5    Haruma, K.6    Chayama, K.7
  • 10
    • 0034255151 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murin model of colorectal carcinoma liver metastases
    • Christiane JB, Wenbiao L, Darren WD, Raymond MS, David JM, Michael RW, Corazon DB, Daniel JH and Lee ME: Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murin model of colorectal carcinoma liver metastases. Cancer 89: 488-499, 2000.
    • (2000) Cancer , vol.89 , pp. 488-499
    • Christiane, J.B.1    Wenbiao, L.2    Darren, W.D.3    Raymond, M.S.4    David, J.M.5    Michael, R.W.6    Corazon, D.B.7    Daniel, J.H.8    Lee, M.E.9
  • 11
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Takahashi Y, Kitadai Y, Bucana CD, Cleary KR and Ellis LM: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 55: 3964-3968, 1995.
    • (1995) Cancer Res , vol.55 , pp. 3964-3968
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 12
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor-1 is basic-helix-loop-helix-PAS heterodimer regulated by cellular 0-2 tension
    • Wang GL, Jiang BH, Rue EA and Semenza GL: Hypoxia-inducible factor-1 is basic-helix-loop-helix-PAS heterodimer regulated by cellular 0-2 tension. Proc Natl Acad Sci USA 92: 5510-5514, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 13
    • 0032030839 scopus 로고    scopus 로고
    • Control of cell lineage-specific development and transcription by bHLH-PAS proteins
    • Crews ST: Control of cell lineage-specific development and transcription by bHLH-PAS proteins. Genes Dev 12: 607-620, 1998.
    • (1998) Genes Dev , vol.12 , pp. 607-620
    • Crews, S.T.1
  • 15
    • 0032213236 scopus 로고    scopus 로고
    • The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
    • Tian H, Hammer RE, Matsumoto AM, Russell DW and McKnight SL: The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev 12: 3320-3324, 1998. (Pubitemid 28520979)
    • (1998) Genes and Development , vol.12 , Issue.21 , pp. 3320-3324
    • Tian, H.1    Hammer, R.E.2    Matsumoto, A.M.3    Russell, D.W.4    McKnight, S.L.5
  • 16
    • 0029842459 scopus 로고    scopus 로고
    • Oxygen sensing and molecular adaptation to hypoxia
    • Bunn HF and Polyton RO: Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76: 839-885, 1996. (Pubitemid 26286080)
    • (1996) Physiological Reviews , vol.76 , Issue.3 , pp. 839-885
    • Bunn, H.F.1    Poyton, R.O.2
  • 17
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
    • Semenza GL: Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15: 551-578, 1999.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 18
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • DOI 10.1074/jbc.272.36.22642
    • Salceda S and Caro J: Hypoxia-inducible factor 1 alpha-(HIF-1 alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. J Biol Chem 272: 22642-22647, 1997. (Pubitemid 27386079)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.36 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 19
    • 0032493368 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor-1 alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
    • Huang LE, Gu J, Schau M and Bunn HF: Regulation of hypoxia-inducible factor-1 alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 95: 7987-7992, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7987-7992
    • Huang, L.E.1    Gu, J.2    Schau, M.3    Bunn, H.F.4
  • 21
    • 1842416574 scopus 로고    scopus 로고
    • Oxygen(es) and the hypoxia-inducible factor-1
    • Wenger RH and Gassmann M: Oxygen(es) and the hypoxia-inducible factor-1. Biol Chem 378: 609-616, 1997. (Pubitemid 27361853)
    • (1997) Biological Chemistry , vol.378 , Issue.7 , pp. 609-616
    • Wenger, R.H.1    Gassmann, M.2
  • 24
    • 0030659531 scopus 로고    scopus 로고
    • V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: Involvement of HIF-1 in tumor progression
    • Jiang BH, Agani F, Passaniti A and Semenza GL: V-SRC induces expression of hypoxia-inducible factor-1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression. Cancer Res 57: 5328-5335, 1997. (Pubitemid 27516371)
    • (1997) Cancer Research , vol.57 , Issue.23 , pp. 5328-5335
    • Jiang, B.-H.1    Agani, F.2    Passaniti, A.3    Semenza, G.L.4
  • 25
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1alpha is required for solid tumor formation and embryonic vascularization
    • DOI 10.1093/emboj/17.11.3005
    • Ryan HE, Lo J and Johnson RS: HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J 17: 3005-3015, 1998. (Pubitemid 28254373)
    • (1998) EMBO Journal , vol.17 , Issue.11 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 27
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • DOI 10.1038/82146
    • Kung AL, Wang S, Klco JM, Kaelin WG and Livingston DM: Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med 6: 1335-1340, 2000. (Pubitemid 32001016)
    • (2000) Nature Medicine , vol.6 , Issue.12 , pp. 1335-1340
    • Kung, A.L.1    Wang, S.2    Klco, J.M.3    Kaelin Jr., W.G.4    Livingston, D.M.5
  • 28
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis-dependent?
    • Folkman J: What is the evidence that tumors are angiogenesis-dependent? J Natl Cancer Inst 82: 4-6, 1990.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 31
    • 0344239658 scopus 로고
    • Expression implications for induction and inhibition of tumor angiogenesis
    • Plate KH, Breier G and Weich HA: Expression implications for induction and inhibition of tumor angiogenesis. Cancer Res 5: 4575-4580, 1995.
    • (1995) Cancer Res , vol.5 , pp. 4575-4580
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3
  • 32
    • 0030021835 scopus 로고    scopus 로고
    • The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences
    • Shima DT, Kuroki M, Deutsch U, Ng YS, Adamis AP and D'Amore PA: The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences. J Biol Chem 271: 3877-3883, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 3877-3883
    • Shima, D.T.1    Kuroki, M.2    Deutsch, U.3    Ng, Y.S.4    Adamis, A.P.5    D'Amore, P.A.6
  • 34
    • 0035413326 scopus 로고    scopus 로고
    • HIF-1alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis
    • Fang J, Yan L, Shing Y and Moses MA: HIF-1-alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis. Cancer Res 61: 5731-5735, 2001. (Pubitemid 32769087)
    • (2001) Cancer Research , vol.61 , Issue.15 , pp. 5731-5735
    • Fang, J.1    Yan, L.2    Shing, Y.3    Moses, M.A.4
  • 38
    • 0026757013 scopus 로고
    • Flow cytometric DNA analysis of gastric smooth muscle tumors
    • Shimamoto T, Haruma K, Sumii K, Kajiyama G and Tahara E: Flow cytometric DNA analysis of gastric smooth muscle tumors. Cancer 70: 2031-2034, 1992.
    • (1992) Cancer , vol.70 , pp. 2031-2034
    • Shimamoto, T.1    Haruma, K.2    Sumii, K.3    Kajiyama, G.4    Tahara, E.5
  • 39
    • 0027497621 scopus 로고
    • Usefulness of nucleolar organizer region staining in gastric myogenic tumors: Correlation with ploidy by DNA flow cytometry
    • Shimamoto T, Haruma K, Tanaka S, Todo H, Yoshihara M, Sumii K and Kajiyama G: Usefulness of nucleolar organizer region staining in gastric myogenic tumors: correlation with ploidy by DNA flow cytometry. Oncology 50: 52-56, 1993. (Pubitemid 23041112)
    • (1993) Oncology , vol.50 , Issue.1 , pp. 52-56
    • Shimamoto, T.1    Haruma, K.2    Tanaka, S.3    Todo, H.4    Yoshihara, M.5    Sumii, K.6    Kajiyama, G.7
  • 40
    • 0027504671 scopus 로고
    • Prognostic value of proliferating cell nuclear antigen index in gastric stromal tumors: Correlation with mitotic count and clinical outcome
    • Amin MB, Ma CK, Linden MD, Kubus JJ and Zarbo RJ: Prognostic value of proliferating cell nuclear antigen index in gastric stromal tumors, correlation with mitotic count and clinical outcome. Am J Clin Pathol 100: 428-432, 1993. (Pubitemid 23296510)
    • (1993) American Journal of Clinical Pathology , vol.100 , Issue.4 , pp. 428-432
    • Amin, M.B.1    Ma, C.K.2    Linden, M.D.3    Kubus, J.J.4    Zarbo, R.J.5
  • 41
    • 7344219816 scopus 로고    scopus 로고
    • Small intestinal stromal tumors: A clinicopathologic study of 31 tumors
    • Chang MS, Choe G, Kim WH and Kim YI: Small intestinal stromal tumors: a clinicopathologic study of 31 tumors. Pathol Int 48: 341-347, 1998. (Pubitemid 28355157)
    • (1998) Pathology International , vol.48 , Issue.5 , pp. 341-347
    • Chang, M.S.1    Choe, G.2    Kim, W.H.3    Kim, Y.I.4
  • 42
    • 0032235314 scopus 로고    scopus 로고
    • Prognostic factors of gastrointestinal stromal tumors of the stomach
    • Hillemanns M, Pasold S, Bottcher K and Hofler H: Prognostic factors of gastrointestinal stromal tumors of the stomach. Verh Dusch Ges Pathol 82: 261-266, 1998.
    • (1998) Verh Dusch Ges Pathol , vol.82 , pp. 261-266
    • Hillemanns, M.1    Pasold, S.2    Bottcher, K.3    Hofler, H.4
  • 43
    • 0030667413 scopus 로고    scopus 로고
    • Small intestinal stromal tumors: A clinicopathologic study of 20 cases with immunohistochemical assessment of cell differentiation and the prognostic role of proliferation antigens
    • Ma CK, De Peralta MN, Amin MB, Linden MD, De Kovich AA, Kubus JJ and Zarbo RJ: Small intestinal stromal tumors: a clinicopathologic study of 20 cases with immunohistochemical assessment of cell differentiation and the prognostic role of proliferating antigens. Am J Clin Pathol 108: 641-651, 1997. (Pubitemid 27506230)
    • (1997) American Journal of Clinical Pathology , vol.108 , Issue.6 , pp. 641-651
    • Ma, C.K.1    De Peralta, M.N.2    Amin, M.B.3    Linden, M.D.4    Dekovich, A.A.5    Kubus, J.J.6    Zarbo, R.J.7
  • 44
    • 0031015032 scopus 로고    scopus 로고
    • Prognostic significance of DNA ploidy and proliferative index (MIB-1 index) in gastrointestinal stromal tumors
    • DOI 10.1016/S0046-8177(97)90100-3
    • Carrillo R, Candia A, Rodriguez-Peralto JL and Caz V: Prognosis significance of DNA ploidy and proliferative index (MIB-1 index) in gastrointestinal stromal tumors. Hum Pathol 28: 160-165, 1997. (Pubitemid 27069180)
    • (1997) Human Pathology , vol.28 , Issue.2 , pp. 160-165
    • Carrillo, R.1    Candia, A.2    Rodriguez-Peralto, J.L.3    Caz, V.4
  • 46
    • 0033814350 scopus 로고    scopus 로고
    • Biological and clinical review of stromal tumors in the gastrointestinal tract
    • Nishida T and Hirota S: Biological and clinical review of stromal tumors in the gastrointestinal tract. Histol Histopathol 15: 1293-1301, 2000.
    • (2000) Histol Histopathol , vol.15 , pp. 1293-1301
    • Nishida, T.1    Hirota, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.