Significance of vessel count and vascular endothelial growth factor in human esophageal carcinomas

Clinical Cancer Research

Volumn 4, Issue 9, 1998, Pages 2195-2200

  Kitadai, Yasuhiko ^a   Haruma, Ken ^a   Tokutomi, Tadashi ^a   Tanaka, Shinji ^a   Sumii, Koji ^a   Carvalho, Monica ^a   Kuwabara, Masaki ^b   Yoshida, Kazuhiro ^b   Hirai, Toshihiro ^b   Kajiyama, Goro ^a   Tahara, Eiichi ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER SURVIVAL; CELL CULTURE; CELL LINE; ESOPHAGUS CANCER; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MICROVASCULATURE; NORTHERN BLOTTING; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL RATE;

BLOTTING, NORTHERN; CARCINOMA, SQUAMOUS CELL; DISEASE PROGRESSION; ENDOTHELIAL GROWTH FACTORS; ESOPHAGEAL NEOPLASMS; HUMANS; LYMPHOKINES; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0031712037     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Folkman, J. How is blood vessel growth regulated in normal and neoplastic tissue? G. H. A. Clowes Memorial Award Lecture. Cancer Res., 46: 467-473, 1986.
2. Folkman, J. What is the evidence that tumors are angiogenesis-dependent? J. Natl. Cancer Inst., 82: 4-6, 1990.
3. Weidner, N., Semple, J. P., Welch, W. R., and Folkman, J. Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N. Engl. J. Med., 324: 1-8, 1991.
4. Macchiarini, P., Fontanini, G., Hardin, M. J., Squartini, F., and Angeletti, C. A. Relation of neovascularization to metastasis of non-small cell lung cancer. Lancet, 340: 145-147, 1992.
5. Weidner, N., Carroll, P. R., Flax, J., Blumenfeld, W., and Folkman, J. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am. J. Pathol., 143: 401-409, 1993.
6. Smith-MacCune, K. K., and Weidner, N. Demonstration and characterization of the angiogenic properties of cervical dysplasia. Cancer Res., 54: 800-804, 1994.
7. Takahashi, Y., Kitadai, Y., Bucana, C. D., Cleary, K., and Ellis, L. M. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res., 55: 3964-3968, 1995.
8. Graham, C. H., Rivers, J., Kerbel, R. S., Stankiewicz, K. S., and White, W. L. Extent of vascularization as a prognostic indicator in thin (<0.76 mm) malignant melanomas. Am. J. Pathol., 145: 570-574, 1994.
9. Tanimoto, H., Yoshida, K., Yokozaki, H., Yasui, W., Nakayama, H., Ito, H., Ohama, K., and Tahara, E. Expression of basic fibroblast growth factor in human gastric carcinomas. Virchows Arch. B Cell Pathol., 61: 263-267, 1991.
10. Takahashi, Y., Cleary, K. R., Mai, M., Kitadai, Y., Bucana, C. D., and Ellis, L. M. Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer. Clin. Cancer Res., 2: 1679-1684, 1996.
11. Yamamoto, S., Yasui, W., Kitadai, Y., Yokozaki, H., Haruma, K., Kajiyama, G., and Tahara, E. Expression of vascular endothelial growth factor in human gastric carcinomas. Pathol. Int., in press, 1998.
12. Kitadai, Y., Haruma, K., Sumii, K., Yamamoto, S., Ue, T., Yokozaki, H., Yasui, W., Ohmoto, K., Kajiyama, G., Fidler, I. J., and Tahara, E. Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. Am. J. Pathol., 152: 93-100, 1998.
13. Boring, C. C., Squires, T. S., Tong, T., and Montgomery, S. Cancer statistics, 1994. CA Cancer J. Clin., 44: 7-26, 1994.
14. Earlam, R., and Cunha-Melo, J. R. Oesophageal squamous cell carcinoma. I. A critical review of surgery. Br. J. Surg., 67: 381-390, 1980.
15. Berse, B., Brown, L., Van De Water, L., Devorak, H., and Senger, D. R. Vascular permeability gene is expressed differentially in a normal tissues, macrophages, and tumors. Mol. Biol. Cell, 3: 211-220, 1992.
16. Houck, K. A., Ferrara, N., Winer, J., Cachianes, G., Li, B., and Leung, D. W. The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol. Endocrinol., 5: 1806-1814, 1991.
17. Ferrara, N., Houck, K. A., Jakeman, L. B., and Leung, D. W. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr. Rev., 13: 18-32, 1992.
18. de-Vries, C., Escobedo, J. A., Ueno, H., Houck, K., Ferrara, N., and Williams, L. T. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science (Washington DC), 255: 989-991, 1992.
19. Terman, B. I., Vermazen, M. D., Carrion, M. E., Dimitrov, D., Armellino, D. C., Gospodarowicz, D., and Bohlen, P. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem. Biophys. Res. Commun., 187: 1579-1586, 1992.
20. Japanese Society for Esophageal Diseases. Guidelines for the Clinical and Pathologic Studies on Carcinoma of the Esophagus, 8th ed. Tokyo: Kanehara, 1992.
21. Radinsky, R., Kraemer, P. M., Raines, M. A., Kung, H. J., and Culp, L. A. Amplification and rearrangement of Kirsten ras oncogene in virus transformed BALB/3T3 cells during malignant tumor progression. Proc. Natl. Acad. Sci. USA, 84: 5143-5147, 1987.
22. Feinberg, A. P., and Vogelstein, B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132: 6-13, 1983.
23. Leung, D. W., Cachianes, G., Kuang, W-J., Goeddele, D. V., and Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science (Washington DC), 246: 1306-1309, 1989.
24. Toi, M., Hoshina, S., Takayanagi, T., and Tominaga, T. Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer. Jpn. J. Cancer Res., 85: 1045-1049, 1994.
25. Mise, M., Arii, S., Higashituji, H., Furutani, M., Niwano, M., Harada, T., Ishigami, S., Toda, Y., Nakayama, H., Fukumoto, M., Fujita, J., and Imamura, M. Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor. Hepatology, 23: 455-464, 1996.
26. Itakura, J., Ishiwata, T., Friess, H., Fujii, H., Matsumoto, Y., Buchler, M. W., and Kork, M. Enhanced expression of vascular endothelial growth factor in human pancreatic cancer correlates with local disease progression. Clin. Cancer Res., 3: 1309-1316, 1997.
27. Kim, K. J., Li, B., Winer, J., Armanini, M., Gillet, N., Philips, H. S., and Ferrara, N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Science (Washington DC), 362: 841-844, 1993.
28. Shweiki, D., Itin, A., Soffer, D., and Keshet, E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature (Lond.), 359: 843-845, 1992.
29. Shima, D. T., Deutsch, U., and D'Amore, P. A. Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability. FEBS Lett., 370: 203-208, 1995.
30. Levy, A. P., Levy, N. S., Wegner, S., and Goldberg, M. A. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J. Biol. Chem., 270: 13333-13340, 1995.
31. Ikeda, E., Achen, M. G., Breier, G., and Risau, W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J. Biol. Chem., 34: 19761-19768, 1995.
32. Goldberg, M. A., and Schneider, J. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J. Biol. Chem., 269: 4355-4359, 1994.
33. Rak, J., Mitsuhashi, Y., Bakyo, L., Filmus, J., Shirakawa, S., Sasazuki, T., and Kerbel, R. S. Mutant ras oncogenes up-regulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis. Cancer Res., 55: 4575-4580, 1995.
34. Keiser, A., Weich, H. A., Brandner, G., Marme, D., and Kolch, W. Mutant p53 potentiates protein kinase-C induction of vascular endothelial growth factor expression. Oncogene, 9: 963-969, 1994.
35. Takahashi, Y., Bucana, C. D., Cleary, K. R., and Ellis, L. M. p53, vessel count, and vascular endothelial growth factor expression in human colon cancer. Int. J. Cancer, 79: 34-38, 1998.
36. Hollstein, M. C., Metcalf, R. A., Welsh, J. A., Montesano, R., and Harris, C. C. Frequent mutation of the p53 gene in human esophageal cancer. Proc. Natl. Acad. Sci. USA, 87: 9958-9961, 1990.
37. Dolecki, G. J., and Connolly, D. T. Effects of a variety of cytokines and including agents on vascular permeability factor mRNA levels in U973 cells. Biochem. Biophys. Res. Commun., 180: 572-578, 1991.
38. Pertovaara, L., Kaipainen, A., Mustonen, T., Orpana, A., Ferrara, N., Saksela, O., and Alitalo, K. Vascular endothelial growth factor is induced in response to transforming growth factor β in fibroblastic and epithelial cells. J. Biol. Chem., 269: 6271-6274, 1994.
39. Goad, D. L., Rubin, J., Wang, H., Tashjian, A. H., and Patterson, C. Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I. Endocrinology. 137: 2262-2268, 1996.
40. Kim, K-W., Bae, S-K., Lee, O-H., Bae, M-H., Lee, M-J., and Park, B. C. Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma. Cancer Res., 58: 348-351, 1998.
41. Cohen, T., Nahari, D., Cerem, L. W., Neufeld, G., and Levi, B. Z. Interleukin 6 induces the expression of vascular endothelial growth factor. J. Biol. Chem., 271: 736-741, 1996.
42. Yoshida, K., Kuniyasu, H., Yasui, W., Kitadai, Y., Toge, T., and Tahara, E. Expression of growth factors and their receptors in human esophageal carcinomas: regulation of expression by epidermal growth factor and transforming growth factor α. J. Cancer Res. Clin. Oncol., 119: 401-407, 1993.
43. Yoshida, K., Kyo, E., Tsuda, T., Tsujino, T., Ito, M., Niimoto, M., and Tahara, E. EGF and TGF-α, the ligands of hyperproduced EGFR in human esophageal carcinoma cells, act as autocrine growth factors. Int. J. Cancer, 45: 131-135, 1990.
44. Inoue, K., Ozeki, Y., Sugamura, Y., Sugiura, Y., and Tanaka, S. Vascular endothelial growth factor expression in primary esophageal squamous cell carcinoma. Cancer (Phila.), 79: 206-213, 1997.
45. Guidi, A. J., Fischer, L., Harris, J. R., and Schnitt, S. J. Microvessel density and distribution in ductal carcinoma in situ of breast. J. Natl. Cancer Inst., 86: 614-619, 1994.
46. Smith, S., and Basu, P. Mast cells in corneal immune reaction. Can. J. Ophthalmol., 5: 173-183, 1970.
47. Bosari, S., Lee, A. K. C., Dlellis, R. A., Wiley, B. D., Healtley, G. J., and Silverman, M. L. Microvessel quantitation and prognosis in invasive breast carcinoma. Hum. Pathol., 23: 755-761, 1992.