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Volumn 3, Issue 5, 2003, Pages 430-437

Exposure, sensitization, and mechanisms of fungus-induced asthma

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CYSTEINE PROTEINASE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 18; INTERLEUKIN 4 RECEPTOR; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR; TOLL LIKE RECEPTOR;

EID: 0142058021     PISSN: 15297322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11882-003-0080-z     Document Type: Review
Times cited : (53)

References (77)
  • 1
    • 0006422025 scopus 로고    scopus 로고
    • The innate immune response of the respiratory epithelium
    • Diamond G, Legarda D, Ryan LK: The innate immune response of the respiratory epithelium. Immunol Rev 2000, 173:27-38.
    • (2000) Immunol. Rev. , vol.173 , pp. 27-38
    • Diamond, G.1    Legarda, D.2    Ryan, L.K.3
  • 2
    • 0031871906 scopus 로고    scopus 로고
    • Inflammatory cells and airway defense against Aspergillus fumigatus
    • Kauffman HF, Tomee JFC: Inflammatory cells and airway defense against Aspergillus fumigatus. Immunol Allergy Clin North Am 1999, 18:619-640.
    • (1999) Immunol. Allergy Clin. North Am. , vol.18 , pp. 619-640
    • Kauffman, H.F.1    Tomee, J.F.C.2
  • 3
    • 0037167308 scopus 로고    scopus 로고
    • Sensitization to airborne moulds and severity of asthma: Cross sectional study from European Community respiratory health survey
    • Zureik M, Neukirch C, Leynaert B, et al.: Sensitization to airborne moulds and severity of asthma: cross sectional study from European Community respiratory health survey. BMJ 2002, 325:411-414.
    • (2002) BMJ , vol.325 , pp. 411-414
    • Zureik, M.1    Neukirch, C.2    Leynaert, B.3
  • 4
    • 0036793981 scopus 로고    scopus 로고
    • An update on pollen and fungal spore aerobiology
    • Burge HA: An update on pollen and fungal spore aerobiology. J Allergy Clin Immunol 2002, 110:544-552.
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 544-552
    • Burge, H.A.1
  • 5
    • 0035096788 scopus 로고    scopus 로고
    • The role and abatement of fungal allergens in allergic diseases
    • Bush RK, Portnoy JM: The role and abatement of fungal allergens in allergic diseases. J Allergy Clin Immunol 2001, 107:S430-S440.
    • (2001) J. Allergy Clin. Immunol. , vol.107
    • Bush, R.K.1    Portnoy, J.M.2
  • 6
    • 0021328688 scopus 로고
    • The allergenic and antigenic properties of spore extracts of Aspergillus fumigatus: A comparative study of spore extracts with mycelium and culture filtrate extracts
    • Kauffman HF, van der Heide S, Beaumont F, et al.: The allergenic and antigenic properties of spore extracts of Aspergillus fumigatus: a comparative study of spore extracts with mycelium and culture filtrate extracts. J Allergy Clin Immunol 1984, 73:567-573.
    • (1984) J. Allergy Clin. Immunol. , vol.73 , pp. 567-573
    • Kauffman, H.F.1    van der Heide, S.2    Beaumont, F.3
  • 7
    • 0027325285 scopus 로고
    • Environmental exposure to Aspergillus fumigatus allergen (Asp f I)
    • Sporik RB, Arruda LK, Woodfolk J, et al.: Environmental exposure to Aspergillus fumigatus allergen (Asp f I). Clin Exp Allergy 1993, 23:326-331.
    • (1993) Clin. Exp. Allergy , vol.23 , pp. 326-331
    • Sporik, R.B.1    Arruda, L.K.2    Woodfolk, J.3
  • 9
    • 0003058855 scopus 로고
    • Composition of the house dust mycoflora in Japanese houses
    • Edited by Samson RA, Flannigan B, Flannigan ME, Verhoef AP. Amsterdam: Elsevier
    • Takatori K, Lee H-J, Ohta T, Shida T: Composition of the house dust mycoflora in Japanese houses. In Health Implications of Fungi in Indoor Environments. Edited by Samson RA, Flannigan B, Flannigan ME, Verhoef AP. Amsterdam: Elsevier, 1994:93-101.
    • (1994) Health Implications of Fungi in Indoor Environments , pp. 93-101
    • Takatori, K.1    Lee, H.-J.2    Ohta, T.3    Shida, T.4
  • 10
    • 0032844577 scopus 로고    scopus 로고
    • Clinical effects of air cleaners in homes of asthmatic children sensitized to pet allergens
    • van der Heide S, van Aalderen WM, Kauffman HF, et al.: Clinical effects of air cleaners in homes of asthmatic children sensitized to pet allergens. J Allergy Clin Immunol 1999, 104:447-451.
    • (1999) J. Allergy Clin. Immunol. , vol.104 , pp. 447-451
    • van der Heide, S.1    van Aalderen, W.M.2    Kauffman, H.F.3
  • 11
    • 0033016328 scopus 로고    scopus 로고
    • Fungal extracellular polysaccharides in house dust as a marker for exposure to fungi: Relations with culturable fungi, reported home dampness, and respiratory symptoms
    • Douwes J, van der Sluis B, Doekes G, et al.: Fungal extracellular polysaccharides in house dust as a marker for exposure to fungi: relations with culturable fungi, reported home dampness, and respiratory symptoms. J Allergy Clin Immunol 1999, 103:494-500.
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 494-500
    • Douwes, J.1    van der Sluis, B.2    Doekes, G.3
  • 14
    • 0021989320 scopus 로고
    • Volumetric aerobiological survey of conidial fungi in the North-East Netherlands. II. Comparison of aerobiological data and skin tests with mould extracts in an asthmatic population
    • Beaumont F, Kauffman HF, de Monchy JG, et al.: Volumetric aerobiological survey of conidial fungi in the North-East Netherlands. II. Comparison of aerobiological data and skin tests with mould extracts in an asthmatic population. Allergy 1985, 40:181-186.
    • (1985) Allergy , vol.40 , pp. 181-186
    • Beaumont, F.1    Kauffman, H.F.2    de Monchy, J.G.3
  • 15
    • 0003179246 scopus 로고    scopus 로고
    • Ten types of microscopically identifiable airborne fungal spores at Leiden, The Netherlands
    • Nikkels AH, Terstegge P, Spieksma FThM: Ten types of microscopically identifiable airborne fungal spores at Leiden, The Netherlands. Aerobiologia 1996, 12:107-112.
    • (1996) Aerobiologia , vol.12 , pp. 107-112
    • Nikkels, A.H.1    Terstegge, P.2    Spieksma, F.T.H.M.3
  • 16
  • 17
    • 0032749788 scopus 로고    scopus 로고
    • Prevalence and residential determinants of fungi within homes in Melbourne, Australia
    • Dharmage S, Bailey M, Raven J, et al.: Prevalence and residential determinants of fungi within homes in Melbourne, Australia. Clin Exp Allergy 1999, 29:1481-1489.
    • (1999) Clin. Exp. Allergy , vol.29 , pp. 1481-1489
    • Dharmage, S.1    Bailey, M.2    Raven, J.3
  • 18
    • 51249163246 scopus 로고
    • Mold biodiversity in homes I: Air and surface analysis of 130 dwellings
    • Beguin H, Nolard N: Mold biodiversity in homes I: Air and surface analysis of 130 dwellings. Aerobiologia 1994, 10:157-166.
    • (1994) Aerobiologia , vol.10 , pp. 157-166
    • Beguin, H.1    Nolard, N.2
  • 19
    • 0002457068 scopus 로고
    • Incidence and clinical characteristics of mould allergy
    • Edited by Al-Doory Y, Domson JF. Philadelphia: Lea and Febiger
    • Howard WA: Incidence and clinical characteristics of mould allergy. In Mould Allergy. Edited by Al-Doory Y, Domson JF. Philadelphia: Lea and Febiger; 1984:147-156.
    • (1984) Mould Allergy , pp. 147-156
    • Howard, W.A.1
  • 20
    • 0022353766 scopus 로고
    • Cultivation of fungi in synthetic and semi-synthetic liquid medium. II. Immunochemical properties of the antigenic and allergenic extracts
    • Heide Svd, Kauffman HF, De Vries K: Cultivation of fungi in synthetic and semi-synthetic liquid medium. II. Immunochemical properties of the antigenic and allergenic extracts. Allergy 1985, 40:592-598.
    • (1985) Allergy , vol.40 , pp. 592-598
    • Heide, S.V.D.1    Kauffman, H.F.2    De Vries, K.3
  • 21
    • 0028295235 scopus 로고
    • Allergenic exposure, IgE-mediated sensitization, and related symptoms in lawn cutters
    • Gautrin D, Vandenplas O, Dewitte J-D, et al.: Allergenic exposure, IgE-mediated sensitization, and related symptoms in lawn cutters. J Allergy Clin Immunol 1994, 93:437-445.
    • (1994) J. Allergy Clin. Immunol. , vol.93 , pp. 437-445
    • Gautrin, D.1    Vandenplas, O.2    Dewitte, J.-D.3
  • 22
    • 0028800864 scopus 로고
    • Aerobiologic and clinical aspects of mold allergy in Europe
    • D'Amato G, Spieksma FThM: Aerobiologic and clinical aspects of mold allergy in Europe. Allergy 1995, 50:870-877.
    • (1995) Allergy , vol.50 , pp. 870-877
    • D'Amato, G.1    Spieksma, F.T.H.M.2
  • 23
    • 0036675507 scopus 로고    scopus 로고
    • Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey
    • Zock JP, Jarvis D, Luczynska C, et al.: Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey. J Allergy Clin Immunol 2002, 110:285-292.
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 285-292
    • Zock, J.P.1    Jarvis, D.2    Luczynska, C.3
  • 25
    • 0026665922 scopus 로고
    • Age-dependency of sensitization to aero-allergens in asthmatics
    • Niemeyer NR, de Monchy JGR: Age-dependency of sensitization to aero-allergens in asthmatics. Allergy 1992, 47:431-435.
    • (1992) Allergy , vol.47 , pp. 431-435
    • Niemeyer, N.R.1    de Monchy, J.G.R.2
  • 26
    • 0026035583 scopus 로고
    • Use of the extended Phadebas RAST panel in the diagnosis of mould allergy in asthmatic children
    • Koivikko A, Viander M, Lanner A: Use of the extended Phadebas RAST panel in the diagnosis of mould allergy in asthmatic children. Allergy 1991, 46:85-91.
    • (1991) Allergy , vol.46 , pp. 85-91
    • Koivikko, A.1    Viander, M.2    Lanner, A.3
  • 28
    • 0034786605 scopus 로고    scopus 로고
    • Prevalence of immunoglobulin E for fungi in atopic children
    • Nolles G, Hoekstra MO, Schouten JP, et al.: Prevalence of immunoglobulin E for fungi in atopic children. Clin Exp Allergy 2001, 31:1564-1570.
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 1564-1570
    • Nolles, G.1    Hoekstra, M.O.2    Schouten, J.P.3
  • 29
    • 0034054050 scopus 로고    scopus 로고
    • IgE-mediated sensitization to mould allergens among patients with allergic respiratory diseases in a desert environment
    • Ezeamuzie CI, Al Ali S, Khan M, et al.: IgE-mediated sensitization to mould allergens among patients with allergic respiratory diseases in a desert environment. Int Arch Allergy Immunol 2000, 121:300-307.
    • (2000) Int. Arch. Allergy Immunol. , vol.121 , pp. 300-307
    • Ezeamuzie, C.I.1    Al Ali, S.2    Khan, M.3
  • 30
    • 0035402131 scopus 로고    scopus 로고
    • Current indoor allergen levels of fungi and cats, but not house dust mites, influence allergy and asthma in adults with high dust mite exposure
    • Dharmage S, Bailey M, Raven J, et al.: Current indoor allergen levels of fungi and cats, but not house dust mites, influence allergy and asthma in adults with high dust mite exposure. Am J Respir Crit Care Med 2001, 164:65-71.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 65-71
    • Dharmage, S.1    Bailey, M.2    Raven, J.3
  • 32
    • 0030895694 scopus 로고    scopus 로고
    • Alternaria as a major allergen for asthma in children raised in a desert environment
    • Halonen M, Stern DA, Wright AL, et al.: Alternaria as a major allergen for asthma in children raised in a desert environment. Am J Respir Crit Care Med 1997, 155:1356-1361.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 1356-1361
    • Halonen, M.1    Stern, D.A.2    Wright, A.L.3
  • 33
    • 0032984743 scopus 로고    scopus 로고
    • Is sensitization to Alternaria alternata a risk factor for severe asthma? A population-based study
    • Neukirch C, Henry C, Leynaert B, et al.: Is sensitization to Alternaria alternata a risk factor for severe asthma? A population-based study. J Allergy Clin Immunol 1999, 103:709-711.
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 709-711
    • Neukirch, C.1    Henry, C.2    Leynaert, B.3
  • 34
    • 0034058643 scopus 로고    scopus 로고
    • Sensitivity to fungal allergens is a risk factor for life-threatening asthma
    • Black PN, Udi AA, Brodie SM: Sensitivity to fungal allergens is a risk factor for life-threatening asthma. Allergy 2000, 55:501-504.
    • (2000) Allergy , vol.55 , pp. 501-504
    • Black, P.N.1    Udi, A.A.2    Brodie, S.M.3
  • 35
    • 0029038123 scopus 로고
    • Effect of environmental molds on risk of death from asthma during the pollen season
    • Targonski PV, Persky VW, Ramekrishnan V: Effect of environmental molds on risk of death from asthma during the pollen season. J Allergy Clin Immunol 1995, 95:955-961.
    • (1995) J. Allergy Clin. Immunol. , vol.95 , pp. 955-961
    • Targonski, P.V.1    Persky, V.W.2    Ramekrishnan, V.3
  • 36
    • 0034518971 scopus 로고    scopus 로고
    • Influence of ambient fungal spores on emergency visits for asthma to a regional children's hospital
    • Dales RE, Cakmak S, Burnett RT, et al.: Influence of ambient fungal spores on emergency visits for asthma to a regional children's hospital. Am J Respir Crit Care Med 2000, 162:2087-2090.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.162 , pp. 2087-2090
    • Dales, R.E.1    Cakmak, S.2    Burnett, R.T.3
  • 37
    • 0025978793 scopus 로고
    • Exposure to an aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma
    • O'Hollaren MT, Yunginger JW, Offord KP, et al.: Exposure to an aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma. N Engl J Med 1991, 324:359-363.
    • (1991) N. Engl. J. Med. , vol.324 , pp. 359-363
    • O'Hollaren, M.T.1    Yunginger, J.W.2    Offord, K.P.3
  • 39
    • 0036688286 scopus 로고    scopus 로고
    • Effects of meteorological conditions on spore plumes
    • Burch M, Leved E: Effects of meteorological conditions on spore plumes. Int J Biometeorol 2002, 46:107-117.
    • (2002) Int. J. Biometeorol. , vol.46 , pp. 107-117
    • Burch, M.1    Leved, E.2
  • 40
    • 0034307339 scopus 로고    scopus 로고
    • The Toll receptor family and microbial recognition
    • Medzhitov R, Janeway C Jr: The Toll receptor family and microbial recognition. Trends Microbiol 2000, 8:452-456.
    • (2000) Trends Microbiol. , vol.8 , pp. 452-456
    • Medzhitov, R.1    Janeway Jr., C.2
  • 41
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B, Nicolas E, Michaut L, et al.: The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996, 86:973-983.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3
  • 42
    • 0037094116 scopus 로고    scopus 로고
    • The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated Candidiasis
    • Netea MG, Van Der Graaf CA, Vonk AG, et al.: The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated Candidiasis. J Infect Dis 2002, 185:1483-1489.
    • (2002) J. Infect. Dis. , vol.185 , pp. 1483-1489
    • Netea, M.G.1    Van Der Graaf, C.A.2    Vonk, A.G.3
  • 43
    • 0036838272 scopus 로고    scopus 로고
    • Role of the toll-like receptor 4 Asp299Gly polymorphism in susceptibility to Candida albicans infection
    • Morre SA, Murillo LS, Spaargaren J, et al.: Role of the toll-like receptor 4 Asp299Gly polymorphism in susceptibility to Candida albicans infection. J Infect Dis 2002, 186:1377-1379.
    • (2002) J. Infect. Dis. , vol.186 , pp. 1377-1379
    • Morre, S.A.1    Murillo, L.S.2    Spaargaren, J.3
  • 44
    • 0037131427 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus
    • Mambula SS, Sau K, Henneke P, et al.: Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J Biol Chem 2002, 277:39320-39326.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39320-39326
    • Mambula, S.S.1    Sau, K.2    Henneke, P.3
  • 45
    • 0034780463 scopus 로고    scopus 로고
    • Differential roles of Toll-like receptors in the elicitation of proinflammatory responses by macrophages
    • Jones BW, Heldwein KA, Means TK, et al.: Differential roles of Toll-like receptors in the elicitation of proinflammatory responses by macrophages. Ann Rheum Dis 2001, 60(Suppl3):iii6-iii12.
    • (2001) Ann. Rheum. Dis. , vol.60 , Issue.SUPPL.
    • Jones, B.W.1    Heldwein, K.A.2    Means, T.K.3
  • 46
    • 0348025419 scopus 로고    scopus 로고
    • Immunopathogenesis of allergic bronchopulmonary aspergillosis and airway remodeling
    • Kauffman HF: Immunopathogenesis of allergic bronchopulmonary aspergillosis and airway remodeling. Front Biosci 2003, 8:E190-E196.
    • (2003) Front Biosci. , vol.8
    • Kauffman, H.F.1
  • 47
    • 0036533649 scopus 로고    scopus 로고
    • Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
    • Asokananthan N, Graham PT, Fink J, et al.: Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 2002, 168:3577-3585.
    • (2002) J. Immunol. , vol.168 , pp. 3577-3585
    • Asokananthan, N.1    Graham, P.T.2    Fink, J.3
  • 48
    • 0033933005 scopus 로고    scopus 로고
    • Protease-dependent activation of epithelial cells by fungal allergens leads to morphologic changes and cytokine production
    • Kauffman HF, Tomee JF, van de Riet MA, et al.: Protease-dependent activation of epithelial cells by fungal allergens leads to morphologic changes and cytokine production. J Allergy Clin Immunol 2000, 105:1185-1193.
    • (2000) J. Allergy Clin. Immunol. , vol.105 , pp. 1185-1193
    • Kauffman, H.F.1    Tomee, J.F.2    van de Riet, M.A.3
  • 49
    • 0031765220 scopus 로고    scopus 로고
    • Unique role of allergens and the epithelium in asthma
    • Thompson PJ: Unique role of allergens and the epithelium in asthma. Clin Exp Allergy 1998, 28:110-116.
    • (1998) Clin. Exp. Allergy , vol.28 , pp. 110-116
    • Thompson, P.J.1
  • 50
    • 0037529442 scopus 로고    scopus 로고
    • Interaction of environmental allergens with airway epithelium as a key component of asthma
    • Kauffman HF: Interaction of environmental allergens with airway epithelium as a key component of asthma. Curr Allergy Asthma Rep 2003, 3:101-108.
    • (2003) Curr. Allergy Asthma Rep. , vol.3 , pp. 101-108
    • Kauffman, H.F.1
  • 51
    • 0033977013 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interactions in the pathogenesis of asthma
    • Holgate ST, Davies DE, Lackie PM, et al.: Epithelial-mesenchymal interactions in the pathogenesis of asthma. J Allergy Clin Immunol 2000, 105:193-204.
    • (2000) J. Allergy Clin. Immunol. , vol.105 , pp. 193-204
    • Holgate, S.T.1    Davies, D.E.2    Lackie, P.M.3
  • 52
    • 0036974399 scopus 로고    scopus 로고
    • Alkaline serine proteinase from Aspergillus fumigatus has synergistic effects on Asp-f-2-induced immune response in mice
    • Kurup VP, Xia JQ, Shen HD, et al.: Alkaline serine proteinase from Aspergillus fumigatus has synergistic effects on Asp-f-2-induced immune response in mice. Int Arch Allergy Immunol 2002, 129:129-137.
    • (2002) Int. Arch. Allergy Immunol. , vol.129 , pp. 129-137
    • Kurup, V.P.1    Xia, J.Q.2    Shen, H.D.3
  • 53
    • 0032613081 scopus 로고    scopus 로고
    • Aspergillus fumigatus-secreted proteases as antigenic molecules and virulence factors
    • edn 2. Edited by Brakhage AA, Jahn B, Schmidt A. Wuppertal, Germany: Axel Schmidt
    • Monod M, Jaton-Ogay K, Reichard U: Aspergillus fumigatus-secreted proteases as antigenic molecules and virulence factors. In Aspergillus fumigatus: Biology, Clinical Aspects and Molecular Approaches to Pathogenicity, edn 2. Edited by Brakhage AA, Jahn B, Schmidt A. Wuppertal, Germany: Axel Schmidt; 1999:182-192.
    • (1999) Aspergillus Fumigatus: Biology, Clinical Aspects and Molecular Approaches to Pathogenicity , pp. 182-192
    • Monod, M.1    Jaton-Ogay, K.2    Reichard, U.3
  • 54
    • 0030941873 scopus 로고    scopus 로고
    • Proteases from Aspergillus fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines
    • Tomee JF, Wierenga ATJ, Hiemstra PS, Kauffman HF: Proteases from Aspergillus fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines. J Infect Dis 1997, 176:300-303.
    • (1997) J. Infect. Dis. , vol.176 , pp. 300-303
    • Tomee, J.F.1    Wierenga, A.T.J.2    Hiemstra, P.S.3    Kauffman, H.F.4
  • 55
    • 0035496033 scopus 로고    scopus 로고
    • The role of indoor allergen exposure in the development of sensitization and asthma
    • Murray CS, Woodcock A, Custovic A: The role of indoor allergen exposure in the development of sensitization and asthma. Curr Opin Allergy Clin Immunol 2001, 1:407-412.
    • (2001) Curr. Opin. Allergy Clin. Immunol. , vol.1 , pp. 407-412
    • Murray, C.S.1    Woodcock, A.2    Custovic, A.3
  • 56
    • 0033060552 scopus 로고    scopus 로고
    • How much asthma is really attributable to atopy?
    • Pearce N, Pekkanen J, Beasley R: How much asthma is really attributable to atopy? Thorax 1999, 54:268-272.
    • (1999) Thorax , vol.54 , pp. 268-272
    • Pearce, N.1    Pekkanen, J.2    Beasley, R.3
  • 57
    • 0035888720 scopus 로고    scopus 로고
    • Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype?
    • Sundeep SS, Babu KS, Holgate ST: Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype? Am J Respir Crit Care Med 2001, 164:1333-1338.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 1333-1338
    • Sundeep, S.S.1    Babu, K.S.2    Holgate, S.T.3
  • 58
    • 12244313861 scopus 로고    scopus 로고
    • A comparison of the airway response to segmental antigen bronchial provocation in atopic asthma and allergic rhinitis
    • Becky Kelly EA, Busse WW, Jarjour NN: A comparison of the airway response to segmental antigen bronchial provocation in atopic asthma and allergic rhinitis. J Allergy Clin Immunol 2003, 111:79-86.
    • (2003) J. Allergy Clin. Immunol. , vol.111 , pp. 79-86
    • Becky Kelly, E.A.1    Busse, W.W.2    Jarjour, N.N.3
  • 59
    • 3142592470 scopus 로고    scopus 로고
    • Allergen induced bronchial inflammation in house dust mite allergic patients with and without asthma
    • In press
    • Lopuhaa CE, Out TA, Jansen HM, et al.: Allergen induced bronchial inflammation in house dust mite allergic patients with and without asthma. Clin Exp Allergy 2003, In press.
    • (2003) Clin. Exp. Allergy
    • Lopuhaa, C.E.1    Out, T.A.2    Jansen, H.M.3
  • 60
    • 0021848962 scopus 로고
    • Damage of the airway epithelium and bronchial reactivity in patients with asthma
    • Laitinen LA, Heino M, Laitinen A, et al.: Damage of the airway epithelium and bronchial reactivity in patients with asthma. Am Rev Respir Dis 1985, 131:599-606.
    • (1985) Am. Rev. Respir. Dis. , vol.131 , pp. 599-606
    • Laitinen, L.A.1    Heino, M.2    Laitinen, A.3
  • 61
    • 0033801806 scopus 로고    scopus 로고
    • Inflammatory and structural changes in the airways of patients with asthma
    • Holgate ST: Inflammatory and structural changes in the airways of patients with asthma. Respir Med 2000, 94(SupplD):S3-S6.
    • (2000) Respir. Med. , vol.94 , Issue.SUPPL. D
    • Holgate, S.T.1
  • 62
    • 0026769303 scopus 로고
    • The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects
    • Montefort S, Roberts JA, Beasley R, et al.: The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects. Thorax 1992, 47:499-503.
    • (1992) Thorax , vol.47 , pp. 499-503
    • Montefort, S.1    Roberts, J.A.2    Beasley, R.3
  • 63
    • 0035131956 scopus 로고    scopus 로고
    • Histopathology of the airway epithelium in an experimental dual-phase model of bronchial asthma
    • Tohda Y, Kubo H, Ito M, et al.: Histopathology of the airway epithelium in an experimental dual-phase model of bronchial asthma. Clin Exp Allergy 2001, 31:135-143.
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 135-143
    • Tohda, Y.1    Kubo, H.2    Ito, M.3
  • 64
    • 0034541409 scopus 로고    scopus 로고
    • Expression of c-erbB receptors and ligands in human nasal epithelium
    • Polosa R, Prosperini C, Tomaselli V, et al.: Expression of c-erbB receptors and ligands in human nasal epithelium. J Allergy Clin Immunol 2000, 106:1124-1131.
    • (2000) J. Allergy Clin. Immunol. , vol.106 , pp. 1124-1131
    • Polosa, R.1    Prosperini, C.2    Tomaselli, V.3
  • 65
    • 0033923224 scopus 로고    scopus 로고
    • Involvement of the epidermal growth factor receptor in epithelial repair in asthma
    • Puddicombe SM, Polosa R, Richter A, et al.: Involvement of the epidermal growth factor receptor in epithelial repair in asthma. FASEB J 2000, 14:1362-1374.
    • (2000) FASEB J. , vol.14 , pp. 1362-1374
    • Puddicombe, S.M.1    Polosa, R.2    Richter, A.3
  • 66
    • 0035295658 scopus 로고    scopus 로고
    • The bronchial epithelium in chronic and severe asthma
    • Davies DE: The bronchial epithelium in chronic and severe asthma. Curr Allergy Asthma Rep 2001, 1:127-133.
    • (2001) Curr. Allergy Asthma Rep. , vol.1 , pp. 127-133
    • Davies, D.E.1
  • 67
    • 0033826756 scopus 로고    scopus 로고
    • Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma
    • Holgate ST, Lackie P, Wilson S, et al.: Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma. Am J Respir Crit Care Med 2000, 162:S113-S117.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.162
    • Holgate, S.T.1    Lackie, P.2    Wilson, S.3
  • 68
    • 0036126772 scopus 로고    scopus 로고
    • Genome-wide search for atopy susceptibility genes in Dutch families with asthma
    • Koppelman GH, Stine OC, Xu J, et al.: Genome-wide search for atopy susceptibility genes in Dutch families with asthma. J Allergy Clin Immunol 2002, 109:498-506.
    • (2002) J. Allergy Clin. Immunol. , vol.109 , pp. 498-506
    • Koppelman, G.H.1    Stine, O.C.2    Xu, J.3
  • 69
    • 0034797233 scopus 로고    scopus 로고
    • A polymorphism in the coding region of interleukin-13 gene is associated with atopy but not asthma in Chinese children
    • Leung TF, Tang NL, Chan IH, et al.: A polymorphism in the coding region of interleukin-13 gene is associated with atopy but not asthma in Chinese children. Clin Exp Allergy 2001, 31:1515-1521.
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 1515-1521
    • Leung, T.F.1    Tang, N.L.2    Chan, I.H.3
  • 70
    • 0037247362 scopus 로고    scopus 로고
    • Polymorphisms in the IL-18 gene are associated with specific sensitization to common allergens and allergic rhinitis
    • Kruse S, Kuehr J, Moseler M, et al.: Polymorphisms in the IL-18 gene are associated with specific sensitization to common allergens and allergic rhinitis. J Allergy Clin Immunol 2003, 111:117-122.
    • (2003) J. Allergy Clin. Immunol. , vol.111 , pp. 117-122
    • Kruse, S.1    Kuehr, J.2    Moseler, M.3
  • 71
    • 0036859789 scopus 로고    scopus 로고
    • Fine mapping of an IgE-controlling gene on chromosome 2q: Analysis of CTLA4 and CD28
    • Howard TD, Postma DS, Koppelman GA, et al.: Fine mapping of an IgE-controlling gene on chromosome 2q: analysis of CTLA4 and CD28. J Allergy Clin Immunol 2002, 110:743-751.
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 743-751
    • Howard, T.D.1    Postma, D.S.2    Koppelman, G.A.3
  • 72
    • 0033010861 scopus 로고    scopus 로고
    • Genetics of allergy and bronchial hyperresponsiveness
    • Howard TD, Wiesch DG, Koppelman GH, et al.: Genetics of allergy and bronchial hyperresponsiveness. Clin Exp Allergy 1999, 29(Suppl2):86-89.
    • (1999) Clin. Exp. Allergy , vol.29 , Issue.SUPPL. 2 , pp. 86-89
    • Howard, T.D.1    Wiesch, D.G.2    Koppelman, G.H.3
  • 73
    • 0034046480 scopus 로고    scopus 로고
    • Independent inheritance of serum immunoglobulin E concentrations and airway responsiveness
    • Palmer LJ, Burton PR, Faux JA, et al.: Independent inheritance of serum immunoglobulin E concentrations and airway responsiveness. Am J Respir Crit Care Med 2000, 161:1836-1843.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 1836-1843
    • Palmer, L.J.1    Burton, P.R.2    Faux, J.A.3
  • 74
    • 0037173639 scopus 로고    scopus 로고
    • Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
    • Van Eerdewegh P, Little RD, Dupuis J, et al.: Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 2002, 418:426-430.
    • (2002) Nature , vol.418 , pp. 426-430
    • Van Eerdewegh, P.1    Little, R.D.2    Dupuis, J.3
  • 75
    • 0037794414 scopus 로고    scopus 로고
    • ADAM 33: Just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness?
    • Holgate ST, Davies DE, Murphy G, et al.: ADAM 33: just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness? Thorax 2003, 58:466-469.
    • (2003) Thorax , vol.58 , pp. 466-469
    • Holgate, S.T.1    Davies, D.E.2    Murphy, G.3
  • 76
    • 0036138963 scopus 로고    scopus 로고
    • Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma
    • Howard TD, Koppelman GH, Xu J, et al.: Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma. Am J Hum Genet 2002, 70:230-236.
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 230-236
    • Howard, T.D.1    Koppelman, G.H.2    Xu, J.3
  • 77
    • 0036302736 scopus 로고    scopus 로고
    • Immunopathogenesis of allergic bronchopulmonary aspergillosis in cystic fibrosis
    • Knutsen AP, Bellone C, Kauffman HF: Immunopathogenesis of allergic bronchopulmonary aspergillosis in cystic fibrosis. J Cystic Fibrosis 2002, 1:76-89.
    • (2002) J. Cystic Fibrosis , vol.1 , pp. 76-89
    • Knutsen, A.P.1    Bellone, C.2    Kauffman, H.F.3


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