Genome-wide search for atopy susceptibility genes in Dutch families with asthma

Journal of Allergy and Clinical Immunology

Volumn 109, Issue 3, 2002, Pages 498-506

  Koppelman, Gerard H ^a   Stine, O Colin ^b   Xu, Jianfeng ^a   Howard, Timothy D ^c   Zheng, Siqun L ^d   Kauffman, Henk F ^a   Bleecker, Eugene R ^a   Meyers, Deborah A ^a   Postma, Dirkje S ^a  

^a Department of Pulmonary Rehabilitation ^*  (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Asthma; Eosinophils; Genetics of atopy; Genome wide search; Specific IgE

Indexed keywords

ALLERGEN; DNA; IMMUNOGLOBULIN E;

ADULT; ARTICLE; ASTHMA; ATOPY; CHILD; CHROMOSOME 11Q; CHROMOSOME 13Q; CHROMOSOME 17Q; CHROMOSOME 22Q; CHROMOSOME 2Q; CHROMOSOME 6P; CHROMOSOME 7Q; CONTROLLED STUDY; EOSINOPHIL; FAMILIAL DISEASE; FEMALE; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOME; HERITABILITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NETHERLANDS; PHENOTYPE; PRIORITY JOURNAL; SKIN TEST;

EID: 0036126772     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2002.122235     Document Type: Article

References (34)

1. Epidemiologic trends
2. Genetics of asthma
3. Review articles. Advances in immunology: Allergy and allergic diseases
4. Evidence for the increase in asthma worldwide
5. Is allergy prevention realistic and beneficial?
6. Major genes regulating total serum immunoglobulin E levels in families with asthma
7. Characterization of obstructive airways disease in family members of probands with asthma: An algorithm for the diagnosis of asthma
8. Linkage designer and linkage reporter software for automated gene localization studies
9. Multipoint quantitative-trait linkage analysis in general pedigrees
10. Parametric and non-parametric linkage analyses: A unified multipoint approach
11. Allele-sharing models: LOD scores and accurate linkage tests
12. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
13. Linkage of asthma to markers on chromosome 12 in a sample of 240 families using quantitative phenotype scores
14. Independent inheritance of serum immunoglobulin E concentrations and airway responsiveness
15. Parametric and nonparametric multipoint linkage analysis with imprinting and two-locus-trait models: Application to mite sensitization
16. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population
17. Genome screen for asthma and related phenotypes in the french EGEA study
18. A genome-wide search for quantitative trait loci underlying asthma
19. Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: Evidence from Afro-Caribbean and Caucasian populations
20. Genetic susceptibility to asthma-bronchial hyperresponsiveness coinherited with a major gene for atopy
21. A European study on the genetics of mite sensitization
22. A major susceptibility locus for atopic dermatitis maps to chromosome 3q21
23. A genome-wide search for linkage to asthma
24. Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population
25. Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families
26. Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: Collaborative Study on the Genetics of Asthma
27. Linkage of circulating eosinophils to markers on chromosome 5q
28. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
29. A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population
30. Evidence for genetic associations between asthma, atopy, and bronchial hyperresponsiveness. A study of 8- to 18-yr old twins
31. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q
32. Exclusion of chromosome 11q and the FCERIB gene as aetiological factors in allergy and asthma in a population of Dutch asthmatic families
33. Atopic dermatitis is associated with a functional mutation in the promoter of the C-C chemokine RANTES
34. The -403 G→ A promoter polymorphism in the RANTES gene is associated with atopy and asthma