The Y181C Substitution in 3′-Azido-3′-deoxythymidine-resistant Human Immunodeficiency Virus, Type 1, Reverse Transcriptase Suppresses the ATP-mediated Repair of the 3′-Azido-3′-deoxythymidine 5′-Monophosphate-terminated Primer

Journal of Biological Chemistry

Volumn 278, Issue 42, 2003, Pages 40464-40472

  Selmi, Boulbaba ^a   Deval, Jérôme ^a   Alvarez, Karine ^a   Boretto, Joëlle ^a   Sarfati, Simon ^b   Guerreiro, Catherine ^b   Canard, Bruno ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; AMINO ACIDS; COMPLEXATION; DNA; ENZYME KINETICS; REACTION KINETICS; RNA;

NUCLEOTIDE BINDING;

VIRUSES;

3' AZIDO 3' DEOXYTHYMIDINE 5' MONOPHOSPHATE TERMINATED PRIMER; ADENOSINE TRIPHOSPHATE; REVERSE TRANSCRIPTASE RIBONUCLEASE H; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

AMINO ACID SUBSTITUTION; ARTICLE; DNA TEMPLATE; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME ACTIVITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RIBONUCLEIC ACID TEMPLATE;

ADENOSINE TRIPHOSPHATE; ANTI-HIV AGENTS; BACTERIOPHAGES; DNA; DNA PRIMERS; DNA REPAIR; DRUG RESISTANCE, VIRAL; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; THYMINE NUCLEOTIDES; TIME FACTORS; ZIDOVUDINE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0142040125     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302928200     Document Type: Article

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