Refined model for primer/template binding by HIV-1 reverse transcriptase: Pre-steady-state kinetic analyses of primer/template binding and nucleotide incorporation events distinguish between different binding modes depending on the nature of the nucleic acid substrate

Journal of Molecular Biology

Volumn 292, Issue 2, 1999, Pages 333-344

  Wöhrl, Birgitta M ^a   Krebs, Ruth ^a   Goody, Roger S ^a   Restle, Tobias ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

DNA synthesis; HIV RT; Kinetics; Nucleic acid structure; Polymerisation

Indexed keywords

DNA; PRIMER DNA; RNA; RNA DIRECTED DNA POLYMERASE;

ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DNA SYNTHESIS; DNA TEMPLATE; ENZYME SUBSTRATE COMPLEX; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOMERISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING;

EID: 0040978680     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3057     Document Type: Article

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