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Volumn 43, Issue 1, 2000, Pages 175-183

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; INDOMETACIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SB 242235; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0034121690     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200001)43:1<175::AID-ANR22>3.0.CO;2-S     Document Type: Article
Times cited : (208)

References (37)
  • 4
    • 0027770052 scopus 로고
    • In vivo differentiation of classical non-steroidal antiinflammatory drugs (NSAID) from cytokine suppressive antiinflammatory drugs (CSAID) and other pharmacological classes using mouse tumor necrosis factor alpha (TNFα) production
    • Griswold DE, Hillegass LM, Breton JJ, Esser KM, Adams JL. In vivo differentiation of classical non-steroidal antiinflammatory drugs (NSAID) from cytokine suppressive antiinflammatory drugs (CSAID) and other pharmacological classes using mouse tumor necrosis factor alpha (TNFα) production. Drugs Clin Res XIX 1993;6:243-8.
    • (1993) Drugs Clin Res XIX , vol.6 , pp. 243-248
    • Griswold, D.E.1    Hillegass, L.M.2    Breton, J.J.3    Esser, K.M.4    Adams, J.L.5
  • 5
    • 10144243335 scopus 로고
    • 1-substituted 4-aryl-5-pyridinylimidazoles: A new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency
    • Boehm JC, Smietana JM, Sorenson ME, Garigipati RS, Gallagher TF, Sheldrake PL, et al. 1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency. J Med Chem 1993;39: 3929-37.
    • (1993) J Med Chem , vol.39 , pp. 3929-3937
    • Boehm, J.C.1    Smietana, J.M.2    Sorenson, M.E.3    Garigipati, R.S.4    Gallagher, T.F.5    Sheldrake, P.L.6
  • 6
    • 0026318171 scopus 로고
    • Inflammatory cytokines: Interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases
    • Dinarello CA. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol 1991;3:941-8.
    • (1991) Curr Opin Immunol , vol.3 , pp. 941-948
    • Dinarello, C.A.1
  • 7
    • 0025274640 scopus 로고
    • Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis
    • Arend WP, Dayer J-M. Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 1990;33: 305-15.
    • (1990) Arthritis Rheum , vol.33 , pp. 305-315
    • Arend, W.P.1    Dayer, J.-M.2
  • 8
    • 0021717618 scopus 로고
    • Cytokines and other mediators in rheumatoid arthritis
    • Dayer JM, Demczuk S. Cytokines and other mediators in rheumatoid arthritis. Springer Semin Immunopathol 1984;7:387-413.
    • (1984) Springer Semin Immunopathol , vol.7 , pp. 387-413
    • Dayer, J.M.1    Demczuk, S.2
  • 9
    • 0029913577 scopus 로고
    • Insights into the role of nitric oxide in inflammatory arthritis
    • Cochran FC, Selph J, Sherman P. Insights into the role of nitric oxide in inflammatory arthritis. Med Res Rev 1966;16:547-63.
    • (1966) Med Res Rev , vol.16 , pp. 547-563
    • Cochran, F.C.1    Selph, J.2    Sherman, P.3
  • 10
    • 0002233301 scopus 로고
    • Proteinases and matrix degradation
    • Kelley WN, Harris ED Jr, Ruddy S, Sledge CB, editors. Philadelphia: WB Saunders
    • Werb Z, Alexander CM. Proteinases and matrix degradation. In: Kelley WN, Harris ED Jr, Ruddy S, Sledge CB, editors. Textbook of rheumatology. 4th ed. Philadelphia: WB Saunders; 1993. p. 248-68.
    • (1993) Textbook of Rheumatology. 4th Ed. , pp. 248-268
    • Werb, Z.1    Alexander, C.M.2
  • 11
    • 0027236839 scopus 로고
    • Role of cytokines in the regulation of bone resorption
    • Roodman GD. Role of cytokines in the regulation of bone resorption. Calcif Tissue Int 1993;53:S94-8.
    • (1993) Calcif Tissue Int , vol.53
    • Roodman, G.D.1
  • 12
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994;372:739-46.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3    Gallagher, T.F.4    Kumar, S.5    Green, D.6
  • 14
    • 0028235297 scopus 로고
    • New directions for biological therapy in rheumatoid arthritis
    • Elliott MJ, Maini RN. New directions for biological therapy in rheumatoid arthritis. Int Arch Allergy Immunol 1994;104:112-5.
    • (1994) Int Arch Allergy Immunol , vol.104 , pp. 112-115
    • Elliott, M.J.1    Maini, R.N.2
  • 15
    • 0030991059 scopus 로고    scopus 로고
    • Biologic agents for treating rheumatoid arthritis: Concepts and progress
    • Moreland LW, Heck LW Jr, Koopman WJ. Biologic agents for treating rheumatoid arthritis: concepts and progress. Arthritis Rheum 1997;40:397-409.
    • (1997) Arthritis Rheum , vol.40 , pp. 397-409
    • Moreland, L.W.1    Heck L.W., Jr.2    Koopman, W.J.3
  • 16
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and in mammalian cells
    • Han J, Lee JD, Bibb SL, Ulevitch RJ. A MAP kinase targeted by endotoxin and in mammalian cells. Science 1994;265:808-11.
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibb, S.L.3    Ulevitch, R.J.4
  • 17
    • 0028022750 scopus 로고
    • Identification of a novel protein kinase cascade stimulated by chemical stress and heat shock which activates MAP kinase-activated protein MAPKAP kinase-2 and induces phosphorylation of the small heat shock proteins
    • Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, et al. Identification of a novel protein kinase cascade stimulated by chemical stress and heat shock which activates MAP kinase-activated protein MAPKAP kinase-2 and induces phosphorylation of the small heat shock proteins. Cell 1994;78: 1027-37.
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3    Morange, M.4    Alonso-Llamazares, A.5    Zamanillo, D.6
  • 18
    • 0028015872 scopus 로고
    • Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27
    • Freshney NW, Rawlinson L, Guesdon F, Jones E, Cowley S, Hsuan J, et al. Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27. Cell 1994; 78:1039-49.
    • (1994) Cell , vol.78 , pp. 1039-1049
    • Freshney, N.W.1    Rawlinson, L.2    Guesdon, F.3    Jones, E.4    Cowley, S.5    Hsuan, J.6
  • 19
    • 0029664650 scopus 로고    scopus 로고
    • Role of CSBP/p38/RK stress response kinase in LPS and cytokine signaling mechanisms
    • Lee JC, Young PR. Role of CSBP/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J Leukoc Biol 1996; 59:152-7.
    • (1996) J Leukoc Biol , vol.59 , pp. 152-157
    • Lee, J.C.1    Young, P.R.2
  • 20
    • 0030426902 scopus 로고    scopus 로고
    • Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
    • Badger AM, Bradbeer JN, Votta B, Lee JC, Adams JL, Griswold DE. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J Pharmacol Exp Ther 1996;279:1453-61.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 1453-1461
    • Badger, A.M.1    Bradbeer, J.N.2    Votta, B.3    Lee, J.C.4    Adams, J.L.5    Griswold, D.E.6
  • 21
    • 0028036678 scopus 로고
    • Pyridinyl imidazoles inhibit the inflammatory phase of delayed type hypersensitivity reactions without affecting T-dependent immune responses
    • Reddy MP, Webb EF, Cassatt D, Maley D, Lee JC, Griswold DE, et al. Pyridinyl imidazoles inhibit the inflammatory phase of delayed type hypersensitivity reactions without affecting T-dependent immune responses. Int J Immunopharmacol 1994;16:795-804.
    • (1994) Int J Immunopharmacol , vol.16 , pp. 795-804
    • Reddy, M.P.1    Webb, E.F.2    Cassatt, D.3    Maley, D.4    Lee, J.C.5    Griswold, D.E.6
  • 22
    • 0024587091 scopus 로고
    • Protective effect of SK&F 86002, a novel dual inhibitor of arachidonic acid metabolism, in murine models of endotoxin shock: Inhibition of tumor necrosis factor as a possible mechanism of action
    • Badger AM, Olivera D, Talmadge JE, Hanna N. Protective effect of SK&F 86002, a novel dual inhibitor of arachidonic acid metabolism, in murine models of endotoxin shock: inhibition of tumor necrosis factor as a possible mechanism of action. Circ Shock 1989;27:51-61.
    • (1989) Circ Shock , vol.27 , pp. 51-61
    • Badger, A.M.1    Olivera, D.2    Talmadge, J.E.3    Hanna, N.4
  • 23
    • 0026725269 scopus 로고
    • Beneficial effects of SK&F 105809, a novel cytokine-suppressive agent, in murine models of endotoxin shock
    • Olivera DL, Esser KM, Lee JC, Greig RG, Badger AM. Beneficial effects of SK&F 105809, a novel cytokine-suppressive agent, in murine models of endotoxin shock. Circ Shock 1992;37:301-6.
    • (1992) Circ Shock , vol.37 , pp. 301-306
    • Olivera, D.L.1    Esser, K.M.2    Lee, J.C.3    Greig, R.G.4    Badger, A.M.5
  • 24
    • 0031803059 scopus 로고    scopus 로고
    • SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes
    • Badger AM, Cook MN, Lark MW, Newman-Tarr TM, Swift BA, Nelson AH, et al. SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes. J Immunol 1998;161:467-73.
    • (1998) J Immunol , vol.161 , pp. 467-473
    • Badger, A.M.1    Cook, M.N.2    Lark, M.W.3    Newman-Tarr, T.M.4    Swift, B.A.5    Nelson, A.H.6
  • 25
    • 0033030207 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase inhibitors - Mechanisms and therapeutic potentials
    • Lee JC, Kassis S, Kumar S, Badger A, Adams JL. p38 mitogen-activated protein kinase inhibitors - mechanisms and therapeutic potentials. Pharmacol Ther 1999;82:389-97.
    • (1999) Pharmacol Ther , vol.82 , pp. 389-397
    • Lee, J.C.1    Kassis, S.2    Kumar, S.3    Badger, A.4    Adams, J.L.5
  • 26
    • 0030924833 scopus 로고    scopus 로고
    • Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site
    • Young PR, McLaughlin MM, Jumar S, Kassis S, Doyle ML, McNulty D, et al. Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J Biol Chem 1997;272:12116-21.
    • (1997) J Biol Chem , vol.272 , pp. 12116-12121
    • Young, P.R.1    McLaughlin, M.M.2    Jumar, S.3    Kassis, S.4    Doyle, M.L.5    McNulty, D.6
  • 27
    • 0031587929 scopus 로고    scopus 로고
    • Novel homologues of CSBP/p38 MAP kinase: Activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
    • Kumar S, McDonnell PC, Gum RJ, Hand AT, Lee JC, Young PR. Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun 1997;235:533-8.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 533-538
    • Kumar, S.1    McDonnell, P.C.2    Gum, R.J.3    Hand, A.T.4    Lee, J.C.5    Young, P.R.6
  • 29
    • 0032582678 scopus 로고    scopus 로고
    • Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059
    • Borsch-Haubold AG, Pasquet S, Watson SP. Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. J Biol Chem 1998;273:28766-72.
    • (1998) J Biol Chem , vol.273 , pp. 28766-28772
    • Borsch-Haubold, A.G.1    Pasquet, S.2    Watson, S.P.3
  • 30
    • 0021134952 scopus 로고
    • Microprocessor-assisted plethysmograph for the measurement of mouse paw volume
    • Webb EF, Griswold DE. Microprocessor-assisted plethysmograph for the measurement of mouse paw volume. J Pharmacol Methods 1984;12:149-53.
    • (1984) J Pharmacol Methods , vol.12 , pp. 149-153
    • Webb, E.F.1    Griswold, D.E.2
  • 31
    • 0001570486 scopus 로고
    • A growth factor for B-cell hybridomas produced by human monocytes
    • Aarden LA, Lansdorp P, de Groot E. A growth factor for B-cell hybridomas produced by human monocytes. Lymphokines 1985; 10:175-85.
    • (1985) Lymphokines , vol.10 , pp. 175-185
    • Aarden, L.A.1    Lansdorp, P.2    De Groot, E.3
  • 33
    • 0024271851 scopus 로고
    • Interleukin-6 (IL-6) in synovial fluid and serum of patients with rheumatic diseases
    • Swaak AJG, Rooyen A, van Nieuwenhuis E, Aarden LA. Interleukin-6 (IL-6) in synovial fluid and serum of patients with rheumatic diseases. Scand J Rheumatol 1988;17:469-74.
    • (1988) Scand J Rheumatol , vol.17 , pp. 469-474
    • Swaak, A.J.G.1    Rooyen, A.2    Van Nieuwenhuis, E.3    Aarden, L.A.4
  • 34
    • 0024269961 scopus 로고
    • Excessive production of IL-6/B cell stimulatory factor-2 in rheumatoid arthritis
    • Hirano T, Matsuda T, Turner M. Excessive production of IL-6/B cell stimulatory factor-2 in rheumatoid arthritis. Eur J Immunol 1988;18:1797-802.
    • (1988) Eur J Immunol , vol.18 , pp. 1797-1802
    • Hirano, T.1    Matsuda, T.2    Turner, M.3
  • 36
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 1995;364:229-33.
    • (1995) FEBS Lett , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.