Humic acid induces oxidative DNA damage, growth retardation, and apoptosis in human primary fibroblasts

Experimental Biology and Medicine

Volumn 228, Issue 4, 2003, Pages 413-423

  Cheng, Mei Ling ^a   Ho, Hung Yao ^a,b   Huang, Yi Wen ^a   Lu, Fung Jou ^c   Chiu, Daniel Tsun Yee ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

8 OHdG; Apoptosis; DNA damage; Growth arrest; Humic acid; ROS; Vitamin E

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALPHA TOCOPHEROL; CELL DNA; HUMIC ACID; REACTIVE OXYGEN METABOLITE; 8-HYDROXY-2'-DEOXYGUANOSINE; DEOXYGUANOSINE; DNA; DRUG DERIVATIVE;

APOPTOSIS; ARTICLE; BLACKFOOT DISEASE; CONTROLLED STUDY; DNA DAMAGE; GROWTH RETARDATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; SKIN FIBROBLAST; CELL CULTURE; CELL DIVISION; DRUG EFFECT; FIBROBLAST; HUMIC SUBSTANCE; METABOLISM; NICK END LABELING;

MELAMPODIUM;

APOPTOSIS; CELL DIVISION; CELLS, CULTURED; DEOXYGUANOSINE; DNA; FIBROBLASTS; HUMANS; HUMIC SUBSTANCES; IN SITU NICK-END LABELING; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; VITAMIN E;

EID: 0141792629     PISSN: 15353702     EISSN: None     Source Type: Journal    
DOI: 10.1177/153537020322800412     Document Type: Article

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