Evolution and clinical implications of the myofibroblast concept

Cardiovascular Research

Volumn 38, Issue 3, 1998, Pages 545-548

  Gabbiani, Giulio ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ACTIVATION; CELL ULTRASTRUCTURE; CYTOKINE PRODUCTION; CYTOSKELETON; GRANULATION TISSUE; MYOFIBROBLAST; PRIORITY JOURNAL; REVIEW; SCAR FORMATION; WOUND CONTRACTION;

ACTINS; APOPTOSIS; CICATRIX; CYTOKINES; FIBROBLASTS; GRANULATION TISSUE; HUMANS; MUSCLE, SMOOTH; WOUND HEALING;

EID: 0032103658     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00065-0     Document Type: Review

References (56)

1. [1] Majno G. The healing hand: man and wound in the ancient world. Cambridge: Harvard University Press, 1975.
2. [2] Carrel A, Hartmann A. Cicatrization of wounds. I. The relation between the size and the rate if its cicatrization. J Exp Med 1916;24:429-450.
3. [3] Abercrombie M, Flint MH, James DW. Wound contraction in relation to collagen formation is scorbutic guinea pigs. J Embryol Exp Morphol 1956;4:167-175.
4. [4] Hoffmann-Beerling H. Adenosintriphosphat als Betriebsstoff von Zellbewegungen. Biochim Biophys Acta 1954;14:182-194.
5. [5] Bray D. Cytoplasmic actin: a comparative study. In: Gordon J, editor. Cold Spring Harbor symposia on quantitative biology: the mechanisms of muscle contraction. Cold Spring Harbor: The Cold Spring Harbor Laboratory, 1973:567-571.
6. [6] Gabbiani G, Ryan GB, Majno G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia 1971;27:549-550.
7. [7] Majno G, Gabbiani G, Hirschel BJ, Ryan GB, Statkov PR. Contraction of granulation tissue in vitro: similarity to smooth muscle. Science 1971;173:548-550.
8. [8] Gabbiani G, Hirschel BJ, Ryan GB, Statkov PR, Majno G. Granulation tissue as a contractile organ. A study of structure and function. Exp Med 1972;135:719-734.
9. [9] Gabbiani G, Majno G. Dupuytren's contracture: fibroblast contraction. Am J Pathol 1972;66:131-146.
10. [10] Ramadori G, Veit T, Schwögler S, et al. Expression of the gene of α-smooth muscle-actin isoform in rat liver and in rat fat-storing (Ito) cells. Virchows Arch B Cell Pathol 1990;59:349-357.
11. [11] Adler KB, Low RB, Leslie KO, Mitchell J, Evans JN. Biology of disease. Contractile cells in normal and fibrotic lung. Lab Invest 1989;60:473-485.
12. [12] Johnson RJ, Iida H, Alpers CE, et al. Expression of smooth muscle cell phenotype by rat mesangial cell sin immune complex nephritis. J Clin Invest 1991;87:847-858.
13. [13] Czernobilsky B, Shezen E, Lifschitz-Mercer B, et al. Alpha smooth muscle actin (α-SM actin) in normal human ovaries, in ovarian stromal hyperplasia and in ovarian neoplasma. Virchows Arch B Cell Pathol 1989;57:55-61.
14. [14] Kapanci Y, Assimacopoulos A, Irlé C, Zwahlen A, Gabbiani G. Contractile interstitial cells in pulmonary septa. J Cell Biol 1974;60:375-392.
15. [15] Sappino AP, Dietrich PY, Widgren S, Gabbiani G. Colonic pericryptal fibroblasts. Differentiation pattern in embryogenesis and phenotypic modulation in epithelial proliferative lesions. Virchows Arch A Pathol Anat 1989;415:551-557.
16. [16] Desmoulière A, Gabbiani G. Modulation of fibroblastic cytoskeletal features during pathological situations: the role of extracellular matrix and cytokines. Cell Motil Cytoskeleton 1994;29:195-203.
17. [17] Sappino AP, Schürch W, Gabbiani G. Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulation. Lab Invest 1990;63:144-161.
18. [18] Low RB, Chaponnier C, Gabbiani G. Organization of actin in epithelial cells during regenerative and neoplastic conditions. Correlation of morphologic, immunofluorescent, and biochemical findings. Lab Invest 1981;44:359-367.
19. [19] Evans JN, Adler KB. The lung strip: evaluation of a method to study contractility of pulmonary parenchyma. Exp Lung Res 1981;2:187-195.
20. [20] Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G. A monoclonal antibody against α-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 1986;103:2787-2796.
21. [21] Gabbiani G, Schmid E, Winter S, et al. Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific α-type actin. Proc Natl Acad Sci USA 1981;78:298-302.
22. [22] Darby I, Skalli O, Gabbiani G. α-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest 1990;63:21-29.
23. [23] Schmitt-Gräff A, Krüger S, Bochard F, Gabbiani G, Denk H. Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers. Am J Pathol 1991;138:1233-1242.
24. [24] Friedman SL. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. New Engl J Med 1993;328:1828-1835.
25. [25] Kapanci Y, Ribaux C, Chaponnier C, Gabbiani G. Cytoskeletal features of alveolar myofibroblasts and pericytes in normal human and rat lung. J Histochem Cytochem 1992;40:1955-1963.
26. [26] Diamond JR, van Goor H, Ding G, Engelmyer E. Myofibroblasts in experimental hydronephrosis. Am J Pathol 1995;146:121-129.
27. [27] Sun Y, Weber KT. Angiotensin converting enzyme and myofibroblasts during tissue repair in the rat heart. J Mol Cell Cardiol 1996;28:851-858.
28. [28] Blankesteijn WM, Essers-Janssen YPG, Verluyten MJA, Daemen MJA, Smits JFM. A homologue of Drosophila tissue polarity gene frizzled is expressed in migrating myofibroblasts in the infarcted rat heart. Nat Med 1997;3:541-544.
29. [29] Schürch W, Seemayer TA, Lagacé R. Stromal myofibroblasts in primary invasive and metastatic carcinoma. A combined immunological, light and electron microscopic study. Virchows Arch A 1981;391:125-139.
30. [30] Ronnov-Jessen L, Petersen OW, Koteliansky VE, Bissell MJ. The origin of the myofibroblasts in breast cancer. J Clin Invest 1995;95:859-873.
31. [31] Lazard D, Sastre X, Frid MG, Glukhova MA, Thiery JP, Koteliansky VE. Expression of smooth muscle-specific proteins in myoepithelium and stromal myofibroblasts of normal and malignant human breast. Proc Natl Acad Sci USA 1993;90:999-1003.
32. [32] Vracko R, Thorning D. Contractile cells in rat myocardial scar tissue. Lab Invest 1991;65:214-227.
33. [33] Estes JM, Vande Berg JS, Adzick NS, MacGillivray TE, Desmoulière A, Gabbiani G. Phenotypic and functional features of myofibroblasts in sheep fetal wounds. Differentiation 1994;56:173-181.
34. [34] Weber KT. Extracellular matrix remodeling in heart failure. A role for de novo angiotensin II generation. Circulation 1997;96:4065-4082.
35. [35] Chiavegato A, Bochaton-Piallat ML, D'Amore E, Sartore S, Gabbiani G. Expression of myosin heavy chain isoforms in mammary epithelial cells in myofibroblasts from different fibrotic settings during neoplasia. Virchows Arch 1995;426:77-86.
36. [36] Schmitt-Gräff A, Desmoulière A, Gabbiani G. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Arch 1994;425:3-24.
37. [37] Gabbiani G, Le Lous M, Bailey AJ, Bazin S, Delaunay A. Collagen and myofibroblasts of granulation tissue. A chemical, ultrastructural an immunologic study. Virchows Arch B Cell Pathol 1976;21:133-145.
38. [38] Zhang K, Rekhter MD, Gordon D, Phan SH. Myofibroblasts and their role in lung collagen gene expression during pulmonary during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study. Am J Pathol 1994;145:114-125.
39. [39] Desmoulière A, Redard M, Darby I, Gabbiani G. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol 1995;146:56-66.
40. [40] Hansson GK, Hellstrand M, Rymo L, Rubbia L, Gabbiani G. Interferon γ inhibits both proliferation and expression of differentiation-specific α-smooth muscle actin in arterial smooth muscle cells. J Exp Med 1989;170:1595-1608.
41. [41] Desmoulière A, Rubbia-Brandt L, Abdiu A, Walz T, Macieira-Coelho A, Gabbiani G. α-smooth muscle actin is expressed in a subpopulation of cultured and cloned fibroblasts and is modulated by γ-interferon. Exp Cell Res 1992;201:64-73.
42. [42] Shi Z, Wakil AE, Rockey DC. Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses. Proc Natl Acad Sci USA 1997;94:10663-10668.
43. [43] Pittet B, Rubbia-Brandt L, Desmoulière A, et al. Effect of γ-interferon on the clinical and biological evolution of hypertrophic scars and Dupuytren's disease: an open pilot study. Plast Reconstr Surg 1994;93:1224-1235.
44. [44] Rubbia-Brandt L, Sappino AP, Gabbiani G. Locally applied GM-CSF induces the accumulation of α-smooth muscle actin containing myofibroblasts. Virchows Arch B Cell Pathol 1991;60:73-82.
45. [45] Serini G, Gabbiani G. Modulation of α-smooth muscle actin expression in fibroblasts by transforming growth factor-β isoforms: an in vivo and in vitro study. Wound Rep Reg 1996;4:277-287.
46. [46] Desmoulière A, Geinoz A, Gabbiani F, Gabbiani G. Transforming growth factor-β 1 induces α-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 1993;122:103-111.
47. [47] Ronnov-Jessen L, Petersen OW. Induction of α-smooth muscle actin by transforming growth factor-β1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia. Lab Invest 1993;68:696-707.
48. [48] Border WA, Noble NA. Transforming growth factor β in tissue fibrosis. New Engl J Med 1994;331:1286-1292.
49. [49] Xing Z, Tremblay GM, Sime PJ, Gauldie J. Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by inductions of transforming growth factor-β1 and myofibroblast accumulation. Am J Pathol 1997;150:59-66.
50. [50] Chadban SJ, Tesch GH, Foti R, Atkins RC, Nikolic-Paterson DJ. Interkeukin-10 is a mesangial cell growth factor in vitro and in vivo. Lab Invest 1997;76:619-627.
51. [51] Serini G, Bochaton-Piallat ML, Zardi L, Gabbiani G. ED-A fibronectin mediates the TGF-β 1 induction of the myofibroblastic phenotype. Abstract.
52. [52] Balza E, Borsi L, Allemmanni G, Zardi L. Transforming growth factor β regulates the levels of different fibronectin isoforms in normal cultured fibroblasts. FEBS Lett 1988;228:42-44.
53. [53] Harris AK, Wild P, Stopak D. Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science 1980;208:177-179.
54. [54] Ingber DE, Dike L, Hansen L, et al. Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. Int Rev Cytol 1994;150:173-224.
55. 2-terminal sequence Ac-EEED of α-smooth muscle actin plays a role in polymerization in vitro and in vivo. J Cell Biol 1995;130:887-895.
56. [56] Ronnov-Jessen L, Petersen OW. A function for filamentous α-smooth muscle actin: retardation of motility in fibroblasts. J Cell Biol 1996;134:67-80.