PI3-kinase and MAP-kinase signaling cascades in AILIM/ICOS- and CD28-costimulated T-cells have distinct functions between cell proliferation and IL-10 production

Biochemical and Biophysical Research Communications

Volumn 310, Issue 3, 2003, Pages 691-702

  Okamoto, Naokazu ^a   Tezuka, Katsunari ^b   Kato, Masako ^a   Abe, Ryo ^a   Tsuji, Takashi ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b JT Inc   (Japan)

Author keywords

AILIM ICOS; CD28; IL 10; IL 2; MAP kinase; PI3 kinase Akt

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATION INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE INDUCIBLE COSTIMULATOR; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CD28 ANTIGEN; CD3 ANTIGEN; ENZYME INHIBITOR; INTERLEUKIN 10; INTERLEUKIN 2; JANUS KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN; PROTEIN KINASE B; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0141757328     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.09.065     Document Type: Article

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