Oxidative stress induces axonal beading in cultured human brain tissue

Neurobiology of Disease

Volumn 13, Issue 3, 2003, Pages 222-229

  Roediger, Ben ^a   Armati, Patricia J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Central nervous system; Human brain tissue; Hydrogen peroxide; Neuronal beading; Oxidative stress

Indexed keywords

ANTIOXIDANT; GLIAL FIBRILLARY ACIDIC PROTEIN; HYDROGEN PEROXIDE; PROTEIN ANTIBODY; TUBULIN;

APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN CELL; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; FETUS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; MICROTUBULE; NERVE CELL; NERVE FIBER; NERVE FIBER DEGENERATION; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0043095315     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-9961(03)00038-X     Document Type: Article

References (54)

1. Aksenov M.Y., Aksenova M.V., Butterfield D.A., Geddes J.W., Markesbery W.R. Protein oxidation in the brain in Alzheimer's disease. Neuroscience. 103:2001;373-383.
2. Behl C. Vitamin E protects neurons against oxidative cell death in vitro more effectively than 17-beta estradiol and induces the activity of the transcription factor NF-kappaB. J. Neural Transm. 107:2000;393-407.
3. Bellomo G., Mirabelli F. Oxidative stress and cytoskeletal alterations. Ann. NY Acad. Sci. 663:1992;97-109.
4. Braak E., Braak H., Mandelkow E.M. A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol. (Berl.). 87:1994;554-567.
5. Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berl.). 82:1991;239-259.
6. Braak H., Braak E., Grundke-Iqbal I., Iqbal K. Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: a third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques. Neurosci. Lett. 65:1986;351-355.
7. Brion J.P. The pathology of the neuronal cytoskeleton in Alzheimer's disease. Biochim. Biophys. Acta. 1160:1992;134-142.
8. Burns R.G., Islam K., Chapman R. The multiple phosphorylation of the microtubule-associated protein MAP2 controls the MAP2: tubulin interaction. Eur. J. Biochem. 141:1984;609-615.
9. Desagher S., Glowinski J., Premont J. Astrocytes protect neurons from hydrogen peroxide toxicity. J. Neurosci. 16:1996;2553-2562.
10. Eiserich J.P., Estevez A.G., Bamberg T.V., Ye Y.Z., Chumley P.H., Beckman J.S., Freeman B.A. Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin: a nitric oxide-dependent mechanism of cellular injury. Proc. Natl. Acad. Sci. USA. 96:1999;6365-6370.
11. Facchinetti F., Dawson V.L., Dawson T.M. Free radicals as mediators of neuronal injury. Cell Mol. Neurobiol. 18:1998;667-682.
12. Floyd R.A. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc. Soc. Exp. Biol. Med. 222:1999;236-245.
13. Gaskin F., Shelanski M.L. Microtubules and intermediate filaments. Essays Biochem. 12:1976;115-146.
14. Gilgun-Sherki Y., Rosenbaum Z., Melamed E., Offen D. Antioxidant therapy in acute central nervous system injury: current state. Pharmacol. Rev. 54:2002;271-284.
15. Goldstein L.S., Yang Z. Microtubule-based transport systems in neurons: the roles of kinesins and dyneins. Annu. Rev. Neurosci. 23:2000;39-71.
16. Good P.F., Werner P., Hsu A., Olanow C.W., Perl D.P. Evidence of neuronal oxidative damage in Alzheimer's disease. Am. J. Pathol. 149:1996;21-28.
17. Halliwell B. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1992;1609-1623.
18. Halliwell B., Clement M.V., Long L.H. Hydrogen peroxide in the human body. FEBS Lett. 486:2000;10-13.
19. Hirai K., Aliev G., Nunomura A., Fujioka H., Russell R.L., Atwood C.S., Johnson A.B., Kress Y., Vinters H.V., Tabaton M., Shimohama S., Cash A.D., Siedlak S.L., Harris P.L., Jones P.K., Petersen R.B., Perry G., Smith M.A. Mitochondrial abnormalities in Alzheimer's disease. J. Neurosci. 21:2001;3017-3023.
20. Hirokawa N. Axonal transport and the cytoskeleton. Curr. Opin. Neurobiol. 3:1993;724-731.
21. Ishihara I., Minami Y., Nishizaki T., Matsuoka T., Yamamura H. Activation of calpain precedes morphological alterations during hydrogen peroxide-induced apoptosis in neuronally differentiated mouse embryonal carcinoma P19 cell line. Neurosci. Lett. 279:2000;97-100.
22. Jortner B.S., Dyer K., Walton A., Ehrich M. Synaptophysin immunoreactive axonal swelling in p-bromophenylacetylurea-induced neuropathy. Neurotoxicology. 18:1997;161-168.
23. Kalaria R.N. The role of cerebral ischemia in Alzheimer's disease. Neurobiol. Aging. 21:2000;321-330.
24. Kehrer J.P. The Haber-Weiss reaction and mechanisms of toxicity. Toxicology. 149:2000;43-50.
25. Lewen A., Matz P., Chan P.H. Free radical pathways in CNS injury. J. Neurotrauma. 17:2000;871-890.
26. Martins R.N., Harper C.G., Stokes G.B., Masters C.L. Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress. J. Neurochem. 46:1986;1042-1045.
27. Mirabelli F., Salis A., Vairetti M., Bellomo G., Thor H., Orrenius S. Cytoskeletal alterations in human platelets exposed to oxidative stress are mediated by oxidative and Ca2+-dependent mechanisms. Arch. Biochem. Biophys. 270:1989;478-488.
28. Morel Y., Barouki R. Repression of gene expression by oxidative stress. Biochem. J. 342:1999;481-496.
29. Neely M.D., Sidell K.R., Graham D.G., Montine T.J. The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin. J. Neurochem. 72:1999;2323-2333.
30. Nemetz P.N., Leibson C., Naessens J.M., Beard M., Kokmen E., Annegers J.F., Kurland L.T. Traumatic brain injury and time to onset of Alzheimer's disease: a population-based study. Am. J. Epidemiol. 149:1999;32-40.
31. Nunomura A., Perry G., Aliev G., Hirai K., Takeda A., Balraj E.K., Jones P.K., Ghanbari H., Wataya T., Shimohama S., Chiba S., Atwood C.S., Petersen R.B., Smith M.A. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol. 60:2001;759-767.
32. Pappolla M.A., Omar R.A., Kim K.S., Robakis N.K. Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease. Am. J. Pathol. 140:1992;621-628.
33. Park J.S., Bateman M.C., Goldberg M.P. Rapid alterations in dendrite morphology during sublethal hypoxia or glutamate receptor activation. Neurobiol. Dis. 3:1996;215-227.
34. Perry G., Kawai M., Tabaton M., Onorato M., Mulvihill P., Richey P., Morandi A., Connolly J.A., Gambetti P. Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton. J. Neurosci. 11:1991;1748-1755.
35. Perry G., Taddeo M.A., Nunomura A., Zhu X., Zenteno-Savin T., Drew K.L., Shimohama S., Avila J., Castellani R.J., Smith M.A. Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. Comp. Biochem. Physiol C. Toxicol. Pharmacol. 133:20002;507-513.
36. Povlishock J.T., Kontos H.A. The role of oxygen radicals in the pathobiology of traumatic brain injury. Hum. Cell. 5:1992;345-353.
37. Praprotnik D., Smith M.A., Richey P.L., Vinters H.V., Perry G. Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress. Acta Neuropathol. (Berl.). 91:1996;1-5.
38. Praticò D., Delanty N. Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease. Am. J. Med. 109:2000;577-585.
39. Ramassamy C., Averill D., Beffert U., Theroux L., Lussier-Cacan S., Cohn J.S., Christen Y., Schoofs A., Davignon J., Poirier J. Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain. Neurobiol. Dis. 7:2000;23-37.
40. Ricart K.C., Fiszman M.L. Hydrogen peroxide-induced neurotoxicity in cultured cortical cells grown in serum-free and serum-containing media. Neurochem. Res. 26:2001;801-808.
41. Rogers K.R., Morris C.J., Blake D.R. Cytoskeletal rearrangement by oxidative stress. Int. J. Tissue React. 11:1989;309-314.
42. Röhrdanz E., Schmuck G., Ohler S., Kahl R. The influence of oxidative stress on catalase and MnSOD gene transcription in astrocytes. Brain Res. 900:2001;128-136.
43. Sahuquillo J., Poca M.A., Amoros S. Current aspects of pathophysiology and cell dysfunction after severe head injury. Curr. Pharm. Des. 7:2001;1475-1503.
44. Sayre L.M., Perry G., Smith M.A. In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders. Methods Enzymol. 309:1999;133-152.
45. Sies H. Oxidative Stress: Oxidants and Antioxidants. 1991;Academic Press, London.
46. Smith M.A., Nunomura A., Zhu X., Takeda A., Perry G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxid. Redox. Signal. 2:2000;413-420.
47. Smith M.A., Rottkamp C.A., Nunomura A., Raina A.K., Perry G. Oxidative stress in Alzheimer's disease. Biochim. Biophys. Acta. 1502:2000;139-144.
48. Sokolova T., Gutterer J.M., Hirrlinger J., Hamprecht B., Dringen R. Catalase in astroglia-rich primary cultures from rat brain: immunocytochemical localization and inactivation during the disposal of hydrogen peroxide. Neurosci. Lett. 297:2001;129-132.
49. Stamer K., Vogel R., Thies E., Mandelkow E., Mandelkow E.M. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J. Cell Biol. 156:2002;1051-1063.
50. Sullivan K.F., Cleveland D.W. Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes. Proc. Natl. Acad. Sci. USA. 83:1986;4327-4331.
51. Vale R.D., Reese T.S., Sheetz M.P. Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell. 42:1985;39-50.
52. Velasco M.E., Smith M.A., Siedlak S.L., Nunomura A., Perry G. Striation is the characteristic neuritic abnormality in Alzheimer disease. Brain Res. 813:1998;329-333.
53. Wilkinson A.E., Bridges L.R., Sivaloganathan S. Correlation of survival time with size of axonal swellings in diffuse axonal injury. Acta Neuropathol. (Berl.). 98:1999;197-202.
54. Zhu X., Raina A.K., Rottkamp C.A., Aliev G., Perry G., Boux H., Smith M.A. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J. Neurochem. 76:2001;435-441.