The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin

Journal of Neurochemistry

Volumn 72, Issue 6, 1999, Pages 2323-2333

  Neely, M D ^a,b   Sidell, K R ^a   Graham, D G ^a   Montine, T J ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

4 Hydroxynonenal; Alzheimer's disease; Lipid peroxidation; Neurite growth; Neuronal microtubules; Tubulin

Indexed keywords

4 HYDROXYNONENAL; TUBULIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CYTOSKELETON; DRUG EFFECT; GENE DISRUPTION; LIPID PEROXIDATION; MICROTUBULE ASSEMBLY; NERVE FIBER GROWTH; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PYRAMIDAL NERVE CELL;

ALDEHYDES; ANIMALS; CELL SURVIVAL; LIPID PEROXIDATION; MICROFILAMENTS; MICROTUBULES; NEURITES; NEUROBLASTOMA; NEURONS; OXIDATIVE STRESS; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0033006380     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0722323.x     Document Type: Article

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