-
1
-
-
0036133115
-
The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease
-
Aliev G., Smith M.A., Seyidova D., et al. The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. Brain Pathol. 12:2002;21-35.
-
(2002)
Brain Pathol.
, vol.12
, pp. 21-35
-
-
Aliev, G.1
Smith, M.A.2
Seyidova, D.3
-
2
-
-
0035370372
-
Insulin/IGF signalling and aging: Seeing the bigger picture
-
Gems D., Partridge L. Insulin/IGF signalling and aging: seeing the bigger picture. Curr. Opin. Genet. Dev. 11:2001;287-292.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 287-292
-
-
Gems, D.1
Partridge, L.2
-
3
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein τ (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I., Iqbal K., Tung Y.C., Quinlan M., Wisniewski H.M., Binder L.I. Abnormal phosphorylation of the microtubule-associated protein τ (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA. 83:1986;4913-4917.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
4
-
-
0034626747
-
Genetic pathways that regulate aging in model organisms
-
Guarente L., Kenyon C. Genetic pathways that regulate aging in model organisms. Nature. 408:2000;255-262.
-
(2000)
Nature
, vol.408
, pp. 255-262
-
-
Guarente, L.1
Kenyon, C.2
-
6
-
-
0034440140
-
A unifying hypothesis of Alzheimer's disease. IV. Causation and sequence of events
-
Heininger, K., 2000. A unifying hypothesis of Alzheimer's disease. IV. Causation and sequence of events. Rev. Neurosci. 11 Spec No.: 213-328.
-
(2000)
Rev. Neurosci.
, vol.11
, Issue.SPEC. NO.
, pp. 213-328
-
-
Heininger, K.1
-
7
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai K., Aliev G., Nunomura A., et al. Mitochondrial abnormalities in Alzheimer's disease. J. Neurosci. 21:2001;3017-3023.
-
(2001)
J. Neurosci.
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
-
8
-
-
0024204731
-
The glucose transporter of the human brain and blood-brain barrier
-
Kalaria R.N., Gravina S.A., Schmidley J.W., Perry G., Harik S.I. The glucose transporter of the human brain and blood-brain barrier. Ann. Neurol. 24:1988;757-764.
-
(1988)
Ann. Neurol.
, vol.24
, pp. 757-764
-
-
Kalaria, R.N.1
Gravina, S.A.2
Schmidley, J.W.3
Perry, G.4
Harik, S.I.5
-
9
-
-
0035917440
-
A conserved regulatory system for aging
-
Kenyon C. A conserved regulatory system for aging. Cell. 105:2001;165-168.
-
(2001)
Cell
, vol.105
, pp. 165-168
-
-
Kenyon, C.1
-
10
-
-
0035929569
-
New leads on the 'how' of Alzheimer's
-
Marx J. New leads on the 'how' of Alzheimer's. Science. 293:2001;2192-2194.
-
(2001)
Science
, vol.293
, pp. 2192-2194
-
-
Marx, J.1
-
11
-
-
0029890685
-
The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu, Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease
-
Mourelatos Z., Gonatas N.K., Stieber A., Gurney M.E., Dal Canto M.C. The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu, Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease. Proc. Nat. Acad. Sci. USA. 93:1996;5472-5477.
-
(1996)
Proc. Nat. Acad. Sci. USA
, vol.93
, pp. 5472-5477
-
-
Mourelatos, Z.1
Gonatas, N.K.2
Stieber, A.3
Gurney, M.E.4
Dal Canto, M.C.5
-
12
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura A., Perry G., Pappolla M.A., et al. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J. Neurosci. 19:1999;1959-1964.
-
(1999)
J. Neurosci.
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
-
13
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A., Perry G., Aliev G., et al. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol. 60:2001;759-767.
-
(2001)
J. Neuropathol. Exp. Neurol.
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
-
14
-
-
0034098189
-
Lipoperoxidation is selectively involved in progressive supranuclear palsy
-
Odetti P., Garibaldi S., Norese R., et al. Lipoperoxidation is selectively involved in progressive supranuclear palsy. J. Neuropathol. Exp. Neurol. 59:2000;393-397.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 393-397
-
-
Odetti, P.1
Garibaldi, S.2
Norese, R.3
-
15
-
-
0343336439
-
Ferritin is associated with the aberrant tau filaments present in progressive supranuclear palsy
-
Perez M., Valpuesta J.M., de Garcini E.M., et al. Ferritin is associated with the aberrant tau filaments present in progressive supranuclear palsy. Am. J. Pathol. 152:1998;1531-1539.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 1531-1539
-
-
Perez, M.1
Valpuesta, J.M.2
De Garcini, E.M.3
-
16
-
-
0034672554
-
Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal
-
Perez M., Cuadros R., Smith M.A., Perry G., Avila J. Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal. FEBS Lett. 486:2000;270-274.
-
(2000)
FEBS Lett.
, vol.486
, pp. 270-274
-
-
Perez, M.1
Cuadros, R.2
Smith, M.A.3
Perry, G.4
Avila, J.5
-
17
-
-
0036118882
-
Formation of aberrant phosphotau fibrillar polymers in neural cultured cells
-
Pérez M., Hernández F., Gómez A., Smith M.A., Perry G., Avila J. Formation of aberrant phosphotau fibrillar polymers in neural cultured cells. Eur. J. Biochem. 269:2002;1484-1489.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 1484-1489
-
-
Pérez, M.1
Hernández, F.2
Gómez, A.3
Smith, M.A.4
Perry, G.5
Avila, J.6
-
18
-
-
0345419152
-
Paired helical filaments from Alzheimer disease patients contain cytoskeletal components
-
Perry G., Rizzuto N., Autilio-Gambetti L., Gambetti P. Paired helical filaments from Alzheimer disease patients contain cytoskeletal components. Proc. Natl. Acad. Sci. USA. 82:1985;3916-3920.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 3916-3920
-
-
Perry, G.1
Rizzuto, N.2
Autilio-Gambetti, L.3
Gambetti, P.4
-
19
-
-
0031880094
-
A suicide note from Alzheimer disease neurons? (News and Views)
-
Perry G., Nunomura A., Smith M.A. A suicide note from Alzheimer disease neurons? (News and Views). Nature Med. 4:1998a;897-898.
-
(1998)
Nature Med.
, vol.4
, pp. 897-898
-
-
Perry, G.1
Nunomura, A.2
Smith, M.A.3
-
20
-
-
0032514882
-
Apoptosis and Alzheimer's disease (Letter)
-
Perry G., Nunomura A., Lucassen P., Lassmann H., Smith M.A. Apoptosis and Alzheimer's disease (Letter). Science. 282:1998b;1268-1269.
-
(1998)
Science
, vol.282
, pp. 1268-1269
-
-
Perry, G.1
Nunomura, A.2
Lucassen, P.3
Lassmann, H.4
Smith, M.A.5
-
22
-
-
0033516947
-
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
-
Perry G., Roder H., Nunomura A., et al. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 10:1999;2411-2415.
-
(1999)
Neuroreport
, vol.10
, pp. 2411-2415
-
-
Perry, G.1
Roder, H.2
Nunomura, A.3
-
24
-
-
0033569839
-
Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease
-
Russell R.L., Siedlak S.L., Raina A.K., Bautista J.M., Smith M.A., Perry G. Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease. Arch. Biochem. Biophys. 370:1999;236-239.
-
(1999)
Arch. Biochem. Biophys.
, vol.370
, pp. 236-239
-
-
Russell, R.L.1
Siedlak, S.L.2
Raina, A.K.3
Bautista, J.M.4
Smith, M.A.5
Perry, G.6
-
25
-
-
0033964859
-
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: A central role for bound transition metals
-
Sayre L.M., Perry G., Harris P.L.R., Liu Y., Schubert K.A., Smith M.A. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J. Neurochem. 74:2000;270-279.
-
(2000)
J. Neurochem.
, vol.74
, pp. 270-279
-
-
Sayre, L.M.1
Perry, G.2
Harris, P.L.R.3
Liu, Y.4
Schubert, K.A.5
Smith, M.A.6
-
26
-
-
8044246570
-
Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging
-
Small G.W., Komo S., La Rue A., et al. Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging. Ann. NY Acad. Sci. 802:1996;70-78.
-
(1996)
Ann. NY Acad. Sci.
, vol.802
, pp. 70-78
-
-
Small, G.W.1
Komo, S.2
La Rue, A.3
-
28
-
-
0030043292
-
In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic
-
Stieber A., Mourelatos Z., Gonatas N.K. In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic. Am. J. Pathol. 148:1996;415-426.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 415-426
-
-
Stieber, A.1
Mourelatos, Z.2
Gonatas, N.K.3
-
29
-
-
0033836580
-
In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of τ induced by 4-hydroxy-2-nonenal modification
-
Takeda A., Smith M.A., Avilá J., et al. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of τ induced by 4-hydroxy-2-nonenal modification. J. Neurochem. 75:2000a;1234-1241.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1234-1241
-
-
Takeda, A.1
Smith, M.A.2
Avilá, J.3
-
30
-
-
0034052839
-
Overexpression of heme oxygenase in neuronal cells, the possible interaction with tau
-
Takeda A., Perry G., Abraham N.G., et al. Overexpression of heme oxygenase in neuronal cells, the possible interaction with tau. J. Biol. Chem. 275:2000b;5395-5399.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5395-5399
-
-
Takeda, A.1
Perry, G.2
Abraham, N.G.3
-
31
-
-
0029795197
-
The pathogenesis of Alzheimer disease: An alternative to the amyloid hypothesis
-
Terry R.D. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J. Neuropath. Exp. Neurol. 55:1996;10231025.
-
(1996)
J. Neuropath. Exp. Neurol.
, vol.55
, pp. 10231025
-
-
Terry, R.D.1
-
33
-
-
0037085455
-
High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal
-
Wataya T., Nunomura A., Smith M.A., et al. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. J. Biol. Chem. 277:2002;4644-4648.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4644-4648
-
-
Wataya, T.1
Nunomura, A.2
Smith, M.A.3
-
34
-
-
0032911488
-
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
-
Zhang J., Perry G., Smith M.A., et al. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am. J. Pathol. 154:1999;1423-1429.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1423-1429
-
-
Zhang, J.1
Perry, G.2
Smith, M.A.3
-
35
-
-
0034978320
-
Hibernation, a model of neuroprotection
-
Zhou F., Zhu X., Castellani R.J., et al. Hibernation, a model of neuroprotection. Am. J. Pathol. 158:2001;2145-2151.
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 2145-2151
-
-
Zhou, F.1
Zhu, X.2
Castellani, R.J.3
-
36
-
-
0033782845
-
Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
-
Zhu X., Rottkamp C.A., Boux H., Takeda A., Perry G., Smith M.A. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J. Neuropathol. Exp. Neurol. 59:2000;880-888.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 880-888
-
-
Zhu, X.1
Rottkamp, C.A.2
Boux, H.3
Takeda, A.4
Perry, G.5
Smith, M.A.6
-
37
-
-
0035142804
-
Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
-
Zhu X., Raina A.K., Rottkamp C.A., et al. Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J. Neurochem. 76:2001a;435-441.
-
(2001)
J. Neurochem.
, vol.76
, pp. 435-441
-
-
Zhu, X.1
Raina, A.K.2
Rottkamp, C.A.3
-
38
-
-
0034797352
-
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: The 'two hit' hypothesis
-
Zhu X., Castellani R.J., Takeda A., et al. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mech. Aging Dev. 123:2001b;39-46.
-
(2001)
Mech. Aging Dev.
, vol.123
, pp. 39-46
-
-
Zhu, X.1
Castellani, R.J.2
Takeda, A.3
-
39
-
-
0034781046
-
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease
-
Zhu X., Rottkamp C.A., Hartzler A., et al. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. J. Neurochem. 79:2001c;311-318.
-
(2001)
J. Neurochem.
, vol.79
, pp. 311-318
-
-
Zhu, X.1
Rottkamp, C.A.2
Hartzler, A.3
|