Inhibiting HIV-1 entry with fusion inhibitors

Current Medicinal Chemistry

Volumn 10, Issue 17, 2003, Pages 1633-1642

  Baldwin, C E ^a   Sanders, R W ^a   Berkhout, B ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Entry inhibitors; Fuseon; Fusion inhibitors; gp41; HIV 1; Resistance mutations; T 20; T20

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); 4 [(4 BROMOPHENYL)(ETHOXYIMINO)METHYL] 1' [(2,4 DIMETHYL 3 PYRIDINYL)CARBONYL] 4' METHYL 1,4' BIPIPERIDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT; ANTIVIRUS AGENT; C 34; CD4 IMMUNOGLOBULIN G2; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR5; ENFUVIRTIDE; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NUCLEOSIDE ANALOG; PEPTIDE DERIVATIVE; PROTEIN INHIBITOR; PROTEINASE INHIBITOR; T 1249; T 649; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL ACTIVITY; CLINICAL TRIAL; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG RESISTANCE; DRUG SAFETY; DRUG SENSITIVITY; DRUG TARGETING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; REVIEW; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS INHIBITION;

CLINICAL TRIALS; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP41; HIV FUSION INHIBITORS; HIV-1; HUMANS; MEMBRANE FUSION; MODELS, BIOLOGICAL; PEPTIDE FRAGMENTS;

EID: 0042924167     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033457124     Document Type: Review

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