Accommodating haploinsufficient tumour suppressor genes in Knudson's model

Oncogene

Volumn 19, Issue 30, 2000, Pages 3434-3438

  Cook, Wendy D ^a,b   McCaw, Benjamin J ^b,c  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Haploinsufficient; p27Kip1; p53; Tumour suppressor

Indexed keywords

PROTEIN P27; PROTEIN P53; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DNA BINDING PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; ONCOPROTEIN; RUNX1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; TUMOR SUPPRESSOR PROTEIN;

CANCER SUSCEPTIBILITY; CARCINOGENIC ACTIVITY; EMBRYO DEVELOPMENT; FAMILIAL CANCER; GENE LOSS; GENE MUTATION; GENETIC MODEL; HAPLOIDY; HUMAN; PRIORITY JOURNAL; REVIEW; TUMOR SUPPRESSOR GENE; ANIMAL; BIOLOGICAL MODEL; COLON TUMOR; GENETICS; RETINOBLASTOMA;

ANIMALS; CELL CYCLE PROTEINS; COLONIC NEOPLASMS; CORE BINDING FACTOR ALPHA 2 SUBUNIT; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DNA-BINDING PROTEINS; GENES, TUMOR SUPPRESSOR; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, GENETIC; PROTO-ONCOGENE PROTEINS; RETINOBLASTOMA; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0034643955     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203653     Document Type: Review

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