LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence

Microbiology

Volumn 148, Issue 3, 2002, Pages 763-772

  Burgess, Nicola A ^a   Kirke, David F ^a   Williams, Paul ^a   Winzer, Klaus ^a   Hardie, Kim R ^a   Meyers, Nicholas L ^a   Aduse Opoku, Joseph ^a   Curtis, Michael A ^a   Cámara, Miguel ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Gingipains; Haemagglutinins; LuxS; Porphyromonas gingivalis; Quorum sensing

Indexed keywords

CYSTEINE; CYSTEINE PROTEINASE; GINGIPAIN R; HEMAGGLUTININ; LACTONE DERIVATIVE; LUCIFERASE; LYSINE; PROTEIN ANTIBODY; RECOMBINANT PROTEIN;

ANAEROBIC BACTERIUM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM CULTURE; BACTERIUM MUTANT; BACTERIUM TRANSFORMATION; BIOSENSOR; CELL DENSITY; CONTROLLED STUDY; ENZYME REGULATION; ESCHERICHIA COLI; GENE MUTATION; GRAM NEGATIVE BACTERIUM; MOLECULAR CLONING; MOLECULE; MOUSE; NONHUMAN; PERIODONTAL DISEASE; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRAIN DIFFERENCE; SUPERNATANT; WESTERN BLOTTING;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MURINAE; NEGIBACTERIA; PORPHYROMONAS; PORPHYROMONAS GINGIVALIS; VIBRIO; VIBRIO HARVEYI;

EID: 0036128062     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-148-3-763     Document Type: Article

References (57)

1. Characterization, genetic analysis and expression of a protease antigen (PrpRI) of Porphyromonas gingivalis W50
2. Maturation of the arginine-specific proteases of Porphyromonas gingivalis W50 is dependent on a functional prR2 protease gene
3. Generation of Lys-gingipain protease activity in Porphyromonas gingivalis W50 is independent of Arg-gingipain protease activities
4. How bacteria talk to each other: Regulation of gene expression by quorum sensing
5. Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: Sequence and function of genes encoding a second sensory pathway
6. Cross-species induction of luminescence in the quorum sensing bacterium Vibrio harveyi
7. Periodontal disease and cardiovascular disease
8. Detection, purification and synthesis of N-acyl homoserine lactone quorum sensing molecules
9. Porphyromonas gingivalis gingipains and adhesion to epithelial cells
10. Signaling system in Porphyromonas gingivalis based on a LuxS protein
11. Cloning and expression of Escherichia coli 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase: Identification of the pfs gene product
12. Molecular genetics and nomenclature of proteases of Porphyromonas gingivalis
13. Shigella flexneri LuxS quorum sensing system modulates virB expression but is not essential for virulence
14. Isolation and characterization of a cloned Porphyromonas gingivalis hemagglutinin from an avirulent strain of Salmonella typhimurium
15. Cloning and characterisation of a new protease gene (prtH) from Porphyromonas gingivalis
16. Intercellular communication in Helicobacter pylori: LuxS is essential for the production of an extracellular signaling molecule
17. Periodontal pathogens produce quorum sensing signal molecules
18. Characterization of a Tn4351-generated hemin uptake mutant of Porphyromonas gingivalis: Evidence for the coordinate regulation of virulence factors by hemin
19. Induction of luciferase synthesis in Beneckea harveyi by other marine bacteria
20. The hemagglutinin gene A (hagA) of Porphyromonas gingivalis 381 contains four large contiguous direct repeats
21. Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in gram-negative bacteria
22. Virulence factors of Porphyromonas gingivalis
23. Evidence for a signaling system in Helicobacter pylori: Detection of a luxS-encoded autoinducer
24. Porphyromonas gingivalis virulence in mice: Induction of immunity to bacterial components
25. Characterization of coaggregation between principal periodontal pathogens
26. Multiple colonization defects in cysteine protease mutant of Porphyromonas gingivalis
27. Life below the gum line: Pathogenic mechanisms of Porphyromonas gingivalis
28. The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-(3-hydroxy-7-cis-tetradecenoyl)-homoserine lactone, via HdtS, a putative novel N-acylhomoserine lactone synthase
29. Construction and preliminary characterization of three hemagglutinin mutants of Porphyromonas gingivalis
30. Quorum sensing and Chromobacterium violaceum: Exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones
31. Biology of asaccharolytic black-pigmented Bacteroides species
32. Development of a simple chemically defined medium for Porphyromonas gingivalis: Requirement for alpha-ketoglutarate
33. Rapid isolation of high-molecular-weight plant DNA
34. Construction and characterization of arginine-specific cysteine proteinase (Arg-gingipain)-deficient mutants of Porphyromonas gingivalis
35. Periodontal infection as a possible risk factor for preterm low birth weight
36. Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (Lys-gingipain) in Porphyromonas gingivalis: Structural relationship with the arginine-specific cysteine proteinase (Arg-gingipain)
37. Molecular cloning and structural characterization of the arg-gingipain proteinase of Porphyromonas gingivalis - Biosynthesis as a proteinase adhesion polyprotein
38. The prpR1 and prR2 arginine-specific protease genes of Porphyromonas gingivalis W50 produce five biochemically distinct enzymes
39. Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes
40. The LuxS family of bacterial autoinducers: Biosynthesis of a novel quorum sensing signal molecule
41. Ecological events in subgingival dental plaque with reference to Bacteroides and Fuso-bacterium species
42. Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli
43. pHG165: A pBR322 copy number derivative of pUC8 for cloning and expression
44. Quorum sensing in Escherichia coli and Salmonella typhimurium
45. Regulation of autoinducer production in Salmonella typhimurium
46. Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: A new family of genes responsible for autoinducer production
47. A novel strategy for the isolation of luxI homologues; evidence for the widespread distribution of a LuxR: LuxI superfamily in enteric bacteria
48. Regulation of protease expression in Porphyromonas gingivalis
49. Quorum sensing and the population dependent control of virulence
50. Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acylhomoserine lactone-mediated quorum sensing
51. LuxS: Its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone
52. Quorum sensing as an integral component of gene regulatory networks in Gram negative bacteria
53. Regulation of Porphyromonas gingivalis fim A (fimbrillin) gene
54. Genetic evidence for the relationship of Porphyromonas gingivalis cysteine protease and hemagglutinin activities