Allele-specific suppression of temperature-sensitive mutations of the Saccharomyces cerevisiae RAD52 gene

Current Genetics

Volumn 29, Issue 3, 1996, Pages 203-210

  Kaytor, Michael D ^a   Livingston, Dennis M ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Mutations; RAD52; Suppressors; Yeast

Indexed keywords

ALLELE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DELETION MUTANT; GENE REPRESSION; GENETIC SCREENING; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TEMPERATURE SENSITIVE MUTANT;

SACCHAROMYCES CEREVISIAE;

EID: 0030021997     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02221549     Document Type: Article

References (28)

1. Adzuma K, Osawa T, Ogawa H (1984) Primary structure of the RAD52 sene in Saccharomyces cerevisiae. Mol Cell Biol 4:2735-2744
2. Basile G, Aker M, Mortimer RK (1992) Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51. Mol Cell Biol 12:3225-3246
3. Becker DM, Guarente L (1991) Electroporation of yeast. Methods Enzymol 194:182-187
4. Boundy-Mills KL, Livingston DM (1993) A Saccharomyces cerevisiae RAD52 allele expressing a C-terminal truncation protein: activities and intragenic complementation of missense mutations. Genetics 133:39-49
5. Calderon IL, Contopoulou CR, Mortimer RK (1983) Isolation and Characterization of yeast DNA repair genes. Curr Genet 93-100
6. Donovan JW, Milne GT, Weaver DT (1994) Homotypic and heterotypic protein associations control Rad51 function in double-strand break repair. Genes Dev 8:2552-2562
7. Dornfeld KJ, Livingston DM (1991) Effects of controlled RAD52 expression on repair and recombination in Saccharomyces cerevisiae. Mol Cell Biol 11:2013-2017
8. Firmenich AE, Elias-Arnanz M, Berg P (1995) A novel allele of Saccharomyces cerevisiae RF A1 that is deficient in recombination and repair and suppressible by RAD52. Mol Cell Biol 15:1620-1631
9. Game JC (1993) DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces. Semin Cancer Biol 4:73-83
10. Hartman PE, Roth JR (1973) Mechanisms of suppression. Adv Genet 17:1-105
11. Haynes RH, Kunz BA (1981) DNA repair and mutagenesis in yeast In: Strathen JN, Jones EW, Broach JR (eds) The molecular biology of the yeast Saccharomyces: life cycle and inheritance. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp 371-414
12. Huffaker TC, Hoyt MA, Botstein D (1987) Genetic analysis of the yeast cytoskeleton. Annu Rev Genet 21:259-284
13. Johnston M, Davis RW (1984) Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol 4:1440-1448
14. Kaytor MD, Livingston DM (1994) Saccharomyces cerevisiae RAD52 alleles temperature-sensitive for the repair of double-strand breaks. Genetics 137:933-944
15. Milne GT, Weaver DT (1993) Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52. Genes Dev 7:1755-1765
16. Milne GT, Ho T, Weaver DT (1995) Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51. Genetics 139:1189-1199
17. Resnick MA (1969) Genetic control of radiation sensitivity in Saccharomyces cerevisiae. Genetics 62:519-531
18. Rothstein RJ (1983) One-step gene disruption in yeast. Methods Enzymol 101:202-211
19. Scherer S, Davis RW (1979) Replacement of chromosome segments with altered DNA sequences constructed in vitro. Proc Natl Acad Sci USA 76:4951-4955
20. Schiestl RH, Gietz RG (1989) High-efficiency transformation of intact yeast cells using single-stranded nucleic acid as a carrier. Curr Genet 16:339-346
21. Schild D (1995) Suppression of a new allele of the yeast RAD52 gene by over-expression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity. Genetics 140:115-127
22. Sherman F (1991) Getting started with yeast. Methods Enzymol 194:3-21
23. Shinohara A, Ogawa H, Ogawa T (1992) Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 69:457-470
24. Shore D, Squire M, Nasmyth KA (1984) Characterization of two genes required for the position-effect control of yeast mating-type genes. EMBO J 3:2817-2823
25. Smith J, Rothstein R (1995) A mutation in the gene encoding the Saccharomyces cerevisiae single-stranded DNA-binding protein Rfa1 stimulates a RAD52-independent pathway for direct-repeat recombination. Mol Cell Biol 15:1632-1641
26. Strike TL (1978) Characterization of mutants of yeast sensitive to X-rays, Thesis. University of California, Davis
27. Stotz A, Linder P (1990) The ADE2 gene of Saccharomyces cerevisiae: sequence and new vectors. Gene 95:91-98
28. Tsao SGS, Brunk CF, Pearlman RE (1983) Hybridization of nucleic acids directly in agarose gels. Anal Biochem 131:365-372