A point mutation in influenza B neuraminidase confers resistance to peramivir and loss of slow binding

Antiviral Research

Volumn 59, Issue 1, 2003, Pages 13-22

  Baum, Ellen Z ^a   Wagaman, Pamela C ^a   Ly, Linh ^a   Turchi, Ignatius ^a   Le, Jianhua ^b   Bucher, Doris ^b   Bush, Karen ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Drug resistance; Influenza virus; Neuraminidase inhibitor

Indexed keywords

4 ACETAMIDO 5 AMINO 3 (1 ETHYLPROPOXY) 1 CYCLOHEXENE 1 CARBOXYLIC ACID; HISTIDINE; HISTIDYLTYROSINE; PEPTIDE; PERAMIVIR; SIALIDASE; SIALIDASE INHIBITOR; TYROSINE; UNCLASSIFIED DRUG; ZANAMIVIR;

ANTIBIOTIC RESISTANCE; ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; ENZYME ASSAY; ENZYME INHIBITION; HEMAGGLUTINATION; IC 50; INFLUENZA VIRUS A; INFLUENZA VIRUS B; INHIBITION KINETICS; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; TISSUE CULTURE; VIRUS ISOLATION; VIRUS MUTANT; VIRUS STRAIN; WILD TYPE;

INFLUENZA VIRUS; INFLUENZAVIRUS B;

EID: 0038798654     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(03)00011-1     Document Type: Article

References (42)

1. Babu Y.S., Chand P., Bantia S., Kotian P., Dehghani A., El-Kattan Y., Lin T.-H., Hutchison T.L., Elliott A.J., Parker C.D., Ananth S.L., Horn L.L., Laver G.W., Montgomery J.A. J. Med. Chem. 43:2000;3482-3486.
2. Bantia, S., Ananth, S., Horn, L., Parker, C., Gulati, U., Chand, P., Babu, Y. and Air, G., 2000. Antivir. Res. 46 (Abstract 82).
3. Bantia S., Parker C.D., Ananth S.L., Horn L.L., Andries K., Chand P., Kotian P.L., Dehghani A., El-Kattan Y., Lin T., Hutchison T.L., Montgomery J.A., Kellog D.L., Babu Y.S. Antimicrob. Agents Chemother. 45:2001;1162-1167.
4. Barnett J.M., Cadman A., Burrell F.M., Madar S.H., Lewis A.P., Tisdale M., Bethell R. Virology. 265:1999;286-295.
5. Barnett J.M., Cadman A., Gor D., Dempsey M., Walters M., Candlin A., Tisdale M., Morley P.J., Owens I.J., Fenton R.J., Lewis A.P., Claas E.C.J., Rimmelzwaan G.F., De Groot R., Osterhaus A.D.M.E. Antimicrob. Agents Chemother. 44:2000;78-87.
6. Baum, E.Z., Andries, K., Willebrords, R., Ly, L., Bush, K., 2000. Antivir. Res. 46 (Abstract 58).
7. Bethell R.C., Hart G.J., Blick T.J., Sahasrabudhe A., McKimm-Breschkin J.L. Methods Mol. Med. 24:2000;367-374.
8. Blick T.J., Tiong T., Sahasrabudhe A., Varghese J.N., Colman P.M., Hart G.J., Bethell R.C., McKimm-Breschkin J.L. Virology. 214:1995;475-484.
9. Bossart-Whitaker P., Carson M., Babu Y.S., Smith C.D., Laver W.G., Air G.M. J. Mol. Biol. 232:1993;1069-1083.
10. Burmeister W.P., Ruigrok R.W., Cusack S. EMBO J. 11:1992;49-56.
11. Burmeister W.P., Baudin F., Cudsack S., Ruigrok R.W.H. Virology. 192:1993;683-686.
12. Colman P.M., Hoyne P.A., Lawrence M.C. J Virol. 67:1993;2972-2980.
13. Finley J.B., Atigadda V.R., Duarte F., Zhao J.J., Brouillette W.J., Air G.M., Luo M. J. Mol. Biol. 293:1999;1107-1119.
14. Gallagher M., Bucher D.J., Dourmashkin R., Davis J.F., Rosenn G., Kilbourne E.D. J. Clin. Microbiol. 20:1984;89-93.
15. Ghate A.A., Air G.M. Virology. 264:1999;265-277.
16. Gubareva L.V., Bethell R., Hart G.J., Murti K.G., Penn C.R., Webster R.G. J. Virol. 70:1996;1818-1827.
17. Gubareva L.V., Robinson M.J., Bethell R.C., Webster R.G. J. Virol. 71:1997;3385-3390.
18. Gubareva L.V., McCullers J.A., Bethell R.C., Webster R.G. J. Infect. Dis. 178:1998;1592-1596.
19. Gubareva L.V., Kaiser L., Hayden F.G. Lancet. 355:2000;827-835.
20. Gubareva L.V., Kaiser L., Matrosovich M.N., Yee S.-H., Hayden F.G. J. Infect. Dis. 183:2001a;523-531.
21. Gubareva L.V., Webster R.G., Hayden F.G. Antimicrob. Agents Chemother. 45:2001;3403-3408.
22. Hart G.J., Bethell R.C. Biochem. Mol. Biol. Int. 36:1995;695-703.
23. Ives J.A.L., Carr J.A., Mendel D.B., Tai C.Y., Lambkin R., Kelly L., Oxford J.S., Hayden F.G., Roberts N.A. Antivir. Res. 55:2002;307-317.
24. Kanegae Y., Sugita S., Endo A., Ishida M., Senya S., Osako K., Nerome K., Oya A. J. Virol. 64:1990;2860-2865.
25. Kati W.M., Saldivar A.S., Mohamadi F., Sham H.L., Laver W.G., Kohlbrenner W.E. Biochem. Biophys. Res. Commun. 244:1998;408-413.
26. Kati W.M., Montgomery D., Carrick R., Gubareva L., Maring C., McDaniel K., Steffy K., Molla A., Hayden F., Kempf D., Kohlbrenner W. Antimicrob. Agents Chemother. 46:2002;1014-1021.
27. Kellogg G.E., Joshi G.S., Abraham D.J. Med. Chem. Res. 1:1991;444-453.
28. Kim C.U., Lew W., Williams M.A., Zhang L., Liu H., Swaminathan S., Bischofberger N., Chen M.S., Tai C.Y., Mendel D.B., Laver W.G., Stevens R.C. J. Am. Chem. Soc. 119:1997;681-690.
29. Kitz R., Wilson I.B. J. Biol. Chem. 237:1962;3245-3249.
30. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. J. Biol. Chem. 193:1951;265-275.
31. McKimm-Breschkin J.L. Antivir. Res. 47:2000;1-17.
32. McKimm-Breschkin J.L., Blick T.J., Sahasrabudhe A., Tiong T., Marshall D., Hart G.J., Bethell R.C., Penn C.R. Antimicrob. Agents Chemother. 40:1996a;40-46.
33. McKimm-Breschkin J.L., McDonald M., Blick T.J., Colman P.M. Virology. 225:1996b;240-242.
34. Pegg M.S., von Itzstein M. Biochem. Mol. Biol. Int. 32:1994;851-858.
35. Sidwell R.W. Expert Opin. Investig. Drugs. 11:2002;859-869.
36. Smee D.F., Sidwell R.W., Morrison A.C., Bailey K.W., Baum E.Z., Ly L., Wagaman P.C. Antivir. Res. 52:2001;251-259.
37. Staschke K.A., Colacino J.M., Baxter A.J., Air G.M., Bansal A., Hornback W.J., Munroe J.E., Laver W.G. Virology. 214:1995;642-646.
38. Stoeckle M.Y., Shaw M.W., Choppin P.W. Proc. Natl. Acad. Sci. U.S.A. 84:1987;2703-2707.
39. Taylor N.R., Cleasby A., Singh O., Skarzynski T., Wonacott A.J., Smith P.W., Sollis S.L., Howes P.D., Cherry P.C., Bethell R., Colman P., Varghese J. J. Med. Chem. 41:1998;798-807.
40. Thompson J.D., Higgins D.G., Gibson T.J. Nucleic Acids Res. 22:1994;4673-4680.
41. von Itzstein M., Wu W.Y., Kok G.B., Pegg M.S., Dyason J.C., Jin B., Phan Tho V., Smythe M.L., White H.F.et al. Nature (Lond., U.K.). 363:1993;418-423.
42. Wang, Z. M., Tai, C. Y., Mendel, D. B., 2000. Antivir. Res. 46 (Abstract 80).