-
1
-
-
0034699492
-
BCX-1812 (RWJ-270201): Discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design
-
(2000)
J. Med. Chem.
, vol.43
, pp. 3482-3486
-
-
Babu, Y.S.1
Chand, P.2
Bantia, S.3
Kotian, P.4
Dehghani, A.5
El Kattan, Y.6
Lin, T.H.7
Hutchison, T.L.8
Elliott, A.J.9
Parker, C.D.10
Ananth, S.L.11
Horn, L.L.12
Laver, G.W.13
Montgomery, J.A.14
-
2
-
-
0035080983
-
Comparison of the antiinfluenza activity of RWJ-270201 with those of oseltamivir and zanamivir
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 1162-1167
-
-
Bantia, S.1
Parker, C.D.2
Ananth, S.L.3
Horn, L.L.4
Andries, K.5
Chand, P.6
Kotian, P.L.7
Dehghani, A.8
El-Kattan, Y.9
Lin, T.10
Hutchinson, T.L.11
Montgomery, J.A.12
Kellog, D.L.13
Babu, Y.S.14
-
4
-
-
17344383981
-
Zanamivir susceptibility monitoring and characterization of influenza virus clinical isolates obtained during phase II clinical efficacy studies
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 78-87
-
-
Barnett, J.M.1
Cadman, A.2
Gor, D.3
Dempsey, M.4
Walters, M.5
Candlin, A.6
Tisdale, M.7
Morley, P.J.8
Owens, I.J.9
Fenton, R.J.10
Lewis, A.P.11
Claas, E.C.12
Rimmelzwaan, G.F.13
De Groot, R.14
Osterhaus, A.D.15
-
11
-
-
0034597724
-
Inhaled zanamivir for the prevention of influenza in families
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1282-1289
-
-
Hayden, F.G.1
Gubareva, L.V.2
Monto, A.S.3
Klein, T.4
Elliott, M.J.5
Hammond, J.M.6
Sharp, S.J.7
Ossi, M.J.8
-
12
-
-
0033530264
-
Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: Randomized controlled trials for prevention and treatment
-
(1999)
JAMA
, vol.282
, pp. 1240-1246
-
-
Hayden, F.G.1
Treanor, J.J.2
Fritz, R.S.3
Lobo, M.4
Betts, R.F.5
Miller, M.6
Kinnersley, N.7
Mills, R.G.8
Ward, P.9
Straus, S.E.10
-
13
-
-
0033777454
-
Oral oseltamivir in human experimental influenza B infection
-
(2000)
Antivir. Ther.
, vol.5
, pp. 205-213
-
-
Hayden, F.G.1
Jennings, L.2
Robson, R.3
Schiff, G.4
Jackson, H.5
Rana, B.6
McClelland, G.7
Ipe, D.8
Roberts, N.9
Ward, P.10
-
15
-
-
15444353753
-
Structureactivity relationship studies of novel carbocyclic influenza neuraminidase inhibitors
-
(1998)
J. Med. Chem.
, vol.41
, pp. 2451-2460
-
-
Kim, C.U.1
Lew, W.2
Williams, M.A.3
Wu, H.4
Zhang, L.5
Chen, X.6
Escarpe, P.A.7
Mendel, D.B.8
Laver, W.G.9
Stevens, R.C.10
-
17
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
(1998)
J. Virol.
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkin, J.L.1
Sahasrabudhe, A.2
Blick, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
22
-
-
0026008031
-
Structural characteristics of the M2 protein of influenza A viruses: Evidence that it forms a tetrameric channel
-
(1991)
Virology
, vol.180
, pp. 617-624
-
-
Sugrue, R.J.1
Hay, A.J.2
-
23
-
-
0031787185
-
Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS 4071
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 3234-3241
-
-
Tai, C.Y.1
Escarpe, P.A.2
Sidwell, R.W.3
Williams, M.A.4
Lew, W.5
Wu, H.6
Kim, C.U.7
Mendel, D.B.8
-
24
-
-
0032510373
-
Dihydropyrancarboxamides related to zanamivir: A new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B
-
(1998)
J. Med. Chem.
, vol.41
, pp. 798-807
-
-
Taylor, N.R.1
Cleasby, A.2
Singh, O.3
Skarzynski, T.4
Wonacott, A.J.5
Smith, P.W.6
Sollis, S.L.7
Howes, P.D.8
Cherry, P.C.9
Bethell, R.10
Colman, P.11
Varghese, J.12
-
25
-
-
17744412173
-
Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: A randomized controlled trial
-
(2000)
JAMA
, vol.283
, pp. 1016-1024
-
-
Treanor, J.J.1
Hayden, F.G.2
Vrooman, P.S.3
Barbarash, P.4
Bettis, R.5
Riff, D.6
Singh, S.7
Kinnersley, N.8
Ward, P.9
Mills, R.G.10
-
30
-
-
0035121720
-
Oral oseltamivir treatment of influenza in children
-
(2001)
Pediatr. Infect. Dis. J.
, vol.20
, pp. 127-133
-
-
Whitley, R.J.1
Hayden, F.G.2
Reisenger, K.S.3
Young, N.4
Dutkowski, R.5
Ipe, D.6
Mills, R.G.7
Ward, P.8
|