A member of the GAGE family of tumor antigens is an anti-apoptotic gene that confers resistance to Fas/CD95/APO-1, interferon-γ, taxol and γ-irradiation

Cancer Biology and Therapy

Volumn 1, Issue 4, 2002, Pages 380-387

  Cilensek, Zoran M ^a   Yehiely, Fruma ^a   Kular, Rupinder K ^a   Deiss, Louis P ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Apoptosis; Cancer therapy; Fas CD95 APO 1; GAGE; Taxol resistance; Tumor antigen; irradiation resistance

Indexed keywords

ANTINEOPLASTIC AGENT; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 8; CASPASE 9; FAS ANTIGEN; GAGE7 PROTEIN, HUMAN; GAMMA INTERFERON; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; TUMOR ANTIGEN; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CHEMISTRY; DRUG RESISTANCE; ENZYME ACTIVATION; GAMMA RADIATION; GENETIC TRANSFECTION; GENETICS; HELA CELL; HUMAN; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; PLASMID; PROGNOSIS; RADIATION RESPONSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; WESTERN BLOTTING;

ANTIGENS, CD95; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CASPASE 8; CASPASE 9; CASPASES; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; GAMMA RAYS; HELA CELLS; HUMANS; INTERFERON TYPE II; JURKAT CELLS; NEOPLASM PROTEINS; PACLITAXEL; PLASMIDS; POLY(ADP-RIBOSE) POLYMERASES; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TRANSFECTION;

EID: 0038495255     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.1.4.11     Document Type: Article

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