-
1
-
-
0002121788
-
The role of uracil misincorporation in thymineless death
-
Anticancer Drug Development Guide: Antifolate Drugs in Cancer Therapy. AL Jackman (ed). Humana Press Inc: Totowa, NJ
-
(1999)
, pp. 409-421
-
-
Aherne, G.W.1
Brown, S.D.2
-
6
-
-
0004315244
-
-
Deoxyuridine triphosphatase (dUTPase) expression and cellular response to TS inhibitors. In Chemistry and Biology of Pteridines and Folates. Pfleider W and Rokos H (eds). Berlin: Blackwell Science
-
(1997)
, pp. 271-274
-
-
Brown, S.D.1
Hardcastle, A.2
Aherne, G.W.3
-
10
-
-
0021331954
-
Purification and properties of the deoxyuridine triphosphate nucleotidohydrolase enzyme derived from HeLa S3 cells: Comparison to a distinct dUTP nucleotidohydrolase induced in herpes simplex virus-infected Hela S3 cells
-
(1984)
J Biol Chem
, vol.259
, pp. 5459-5464
-
-
Caradonna, S.J.1
Adamkiewicz, D.M.2
-
13
-
-
0025832444
-
Mechanisms of cell death following thymidylate synthase inhibition: 2 Deoxyuridine 5 triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole
-
(1991)
Cancer Res
, vol.51
, pp. 2346-2352
-
-
Curtin, N.J.1
Harris, A.L.2
Aherne, G.W.3
-
14
-
-
0030670390
-
The relationship between intrinsic thymidylate synthase expression and sensitivity to thymilaq in human leukaemia and colorectal carcinoma Cell lines
-
(1997)
Br J Cancer
, vol.76
, pp. 1579-1585
-
-
Estlin, E.J.1
Babmanno, K.2
Calvert, A.H.3
Hall, A.G.4
Lunec, J.5
Newell, D.R.6
Pearson, A.D.7
Taylor, G.A.8
-
16
-
-
0027279128
-
Bcl-2 modulation apoptosis induced by anticancer drugs-resistance to thymidylate stress is independent of classical resistance pathways
-
(1993)
Cancer Res
, vol.53
, pp. 3321-3326
-
-
Fisher, T.C.1
Milner, A.E.2
Gregory, C.D.3
Jackman, A.L.4
Aherne, G.W.5
Hartley, J.A.6
Drive, C.7
Hickman, J.8
-
23
-
-
0029031286
-
Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines
-
(1995)
Br J Cancer
, vol.71
, pp. 914-924
-
-
Jackman, A.L.1
Kelland, L.R.2
Kimbell, R.3
Brown, M.4
Gibson, W.5
Aherne, G.W.6
Hardcastle, A.7
Boyle, F.T.8
-
24
-
-
0030988738
-
Cellular pharmacology and in vivo activity of a new anticancer agent ZD9331: A water-soluble, nonpolyglutamatable, quinazoline inhibitor of thymidylate synthase
-
(1997)
Clin Cancer Res
, vol.3
, pp. 911-921
-
-
Jackman, A.L.1
Kimbell, R.2
Aherne, G.W.3
Brunton, L.4
Jansen, G.5
Stephens, T.C.6
Smith, M.C.7
Wardleworth, J.M.8
Boyle, F.T.9
-
25
-
-
0021015054
-
Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-((2-amino-4-hydroxy-6-quinazolinyl)-methyl)prop-2-ynylamino)benzoy)-L -glutamic acid (CB3717), on human lymphoblastoid cells
-
(1983)
Biochem Pharmacol
, vol.32
, pp. 3783-3790
-
-
Jackson, R.C.1
Jackman, A.L.2
Calvert, A.H.3
-
26
-
-
0028151449
-
The rule of thymidylate synthase expression in prognosis and outcome or adjuvant chemotherapy in patients with rectal cancer
-
(1994)
J Clin Oncol
, vol.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.R.2
Rockette, H.E.3
Fisher, B.4
Wolmark, N.5
Drake, J.C.6
Chabner, B.A.7
Allergra, C.J.8
-
28
-
-
0031019404
-
Thymidylate synthase expression and response to neoadjuvant chemotherapy in patients with advanced head and neck cancer
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 308-313
-
-
Johnston, P.G.1
Mick, R.2
Recant, W.3
Behan, K.A.4
Dolan, M.E.5
Ratain, M.J.6
Beckman, E.7
Weichselbaum, R.R.8
Allegra, C.J.9
Vokes, E.E.10
-
33
-
-
9044250848
-
Thymidylate synthase mRNA level in adenocarcinoma of the stomach: A predictor for primary turnout response and overall survival
-
(1995)
J Clin Oncol
, vol.14
, pp. 176-182
-
-
Lenz, H.J.1
Leichman, C.G.2
Danenberg, K.D.3
Danenberg, P.V.4
Grohen, S.5
Cohen, H.6
Laine, L.7
Crookes, P.8
Silberman, H.9
Baranda, J.10
Garcia, Y.11
Li, J.12
Leichman, L.13
-
37
-
-
0030986625
-
Prognostic importance of thymidylate synthase expression in early breast cancer
-
(1997)
J Clin Oncol
, vol.15
, pp. 1923-1931
-
-
Pestalozzi, B.C.1
Peterson, H.F.2
Gelber, R.D.3
Goldhirsch, A.4
Fusterson, B.A.5
Trihia, H.6
Lindtner, J.7
Cortes-Funes, H.8
Simmoncini, E.9
Hyrne, M.J.10
Golouh, R.11
Rudenstam, C.M.12
Castiglione-Gertsch, M.13
Allegra, C.J.14
Johnston, P.G.15
-
41
-
-
0027254420
-
Maturation stage and proliferatopm-dependent expression of dUTP Pase in human T-cells
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4991-4995
-
-
Strahler, J.R.1
Zhu, X.-X.2
Hora, N.3
Wang, Y.K.4
Andres, P.C.5
Roseman, N.A.6
Neel, J.V.7
Turka, L.8
Hanash, S.M.9
-
42
-
-
0032994840
-
Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines
-
(1999)
Clin Cancer Res
, vol.5
, pp. 643-654
-
-
Van Triest, B.1
Pinedo, H.M.2
Van Hensbergen, Y.3
Smid, K.4
Telleman, F.5
Schoenmakers, P.S.6
Van der Wilt, C.L.7
Van Laar, J.A.M.8
Noordhuis, P.9
Jansen, G.10
Peters, G.J.11
-
43
-
-
9044239673
-
AG337 is a novel lipophilic thymidylate synthase inhibitor: In vitro and in vivo preclinical studies
-
(1996)
Cancer Chemother Pharmacol
, vol.37
, pp. 309-317
-
-
Webber, S.1
Bartlett, C.2
Boritzki, T.J.3
Hillard, J.A.4
Howland, E.F.5
Johnston, A.L.6
Kosa, M.7
Margosiak, S.A.8
Morse, C.A.9
Shetty, D.V.10
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