Translational Control and Insulin Signaling

Handbook of Cell Signaling: Volume 1-3

Volumn 1-3, Issue , 2003, Pages 305-309

  Radimerski, Thomas ^a   Thomas, George ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0038160611     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012124546-7/50677-X     Document Type: Chapter

References (66)

1. J.W.B. Hershey (1991) Translational control in mammalian cells. Annu. Rev. Biochem. 60 717-755.
2. P.B. Dennis, S. Fumagalli and G. Thomas (1999) Target of rapamycin (TOR): Balancing the opposing forces of protein synthesis and degradation. Curr. Opin. Genet. Dev. 9 49-54.
3. A.C. Gingras, B. Raught and N. Sonenberg (2001) Regulation of translation initiation by FRAP/mTOR. Genes Dev. 15(7), 807-826.
4. C.G. Proud and R.M. Denton (1997) Molecular mechanisms for the control of translation by insulin. Biochem. J. 328(Pt 2), 329-341.
5. G. Thomas (2000) An “encore” for ribosome biogenesis in cell proliferation. Nat. Cell Biol. 2 E71-E72.
6. O. Meyuhas, D. Avni and S. Shama (1996) Translational control of ribosomal protein mRNAs in eukaryotes. J.W.B. Hershey, M.B. Mathews, N. Sonenberg,(Eds) Translational Control Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press 363-388.
7. O. Meyuhas (2000) Synthesis of the translational apparatus is regulated at the translational level. Eur. J. Biochem. 267(21), 6321-6330.
8. R.T. Peterson and S.L. Schreiber (1998) Translation control: connecting mitogens and the ribosome. Curr. Biol. 8 R248-R250.
9. D.A. Antonetti, et al. (1993) Regulation of rDNA transcription by insulin in primary cultures of rat hepatocytes. J. Biol. Chem. 268(34), 25277-25284.
10. J.P. Whitehead (2000) Signalling through the insulin receptor. Curr. Opin Cell Biol. 12(2), 222-228.
11. M. Frodin and S. Gammeltoft (1999) Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction. Mol. Cell Endocrinol. 151(1–2), 65-77.
12. S.J. Leevers, B. Vanhaesebroeck and M.D. Waterfield (1999) Signalling through phosphoinositide 3-kinases: The lipids take centre stage. Curr. Opin Cell Biol. 11(2), 219-225.
13. D.P. Brazil and B.A. Hemmings (2001) Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem. Sci. 26(11), 657-664.
14. T. Maehama and J.E. Dixon (1999) PTEN: A tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol. 9(4), 125-128.
15. N. Pullen and G. Thomas (1997) The modular phosphorylation and activation of p70s6k. FEBS Lett. 410 78-82.
16. V.M. Pain (1996) Initiation of protein synthesis in eukaryotic cells. Eur. J. Biochem. 236(3), 747-771.
17. G.I. Welsh and C.G. Proud (1993) Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B. Biochem. J. 294 625-629.
18. A.V. Skurat and P.J. Roach (1995) Phosphorylation of sites 3a and 3b (Ser640 and Ser644) in the control of rabbit muscle glycogen synthase. J. Biol. Chem. 270(21), 12491-12497.
19. D.A. Cross, et al. (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378 785-789.
20. C.A. Towle, et al. (1984) Insulin promoted decrease in the phosphorylation of protein synthesis initiation factor eIF-2. Biochem. Biophys. Res. Commun. 121 134-140.
21. T.V. Pestova, et al. (2001) Molecular mechanisms of translation initiation in eukaryotes. Proc. Natl. Acad. Sci. USA 98(13), 7029-7036.
22. F. Rozen, et al. (1990) Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F. Mol. Cell Biol. 10(3), 1134-1144.
23. R. Duncan, S.C. Milburn and J.W.B. Hershey (1987) Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control: Heat shock effects eIF-4F. J. Biol. Chem. 262 380-388.
24. A.J. Waskiewicz, et al. (1999) Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo. Mol. Cell Biol. 19(3), 1871-1880.
25. S. Pyronnet, et al. (1999) Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E. EMBO J. 18(1), 270-279.
26. W.B. Minich, et al. (1994) Chromatographic resolution of in vivo phosphorylated and nonphosphorylated eukaryotic translation initiation factor eIF-4E: Increased cap affinity of the phosphorylated form. Proc. Natl. Acad. Sci. USA 91 7668-7672.
27. U. Knauf, C. Tschopp and H. Gram (2001) Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2. Mol. Cell Biol. 21(16), 5500-5511.
28. A. Pause, et al. (1994) Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function. Nature 371 762-767.
29. T.A. Lin, et al. (1995) Control of PHAS-I by insulin in 3T3-L1 adipocytes. J. Biol. Chem. 270 18531-18538.
30. A.C. Gingras, et al. (2001) Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev. 15(21), 2852-2864.
31. X. Wang, et al. (2001) Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J. 20(16), 4370-4379.
32. B. Raught, et al. (2000) Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. EMBO J. 19(3), 434-444.
33. P.B. Dennis and G. Thomas (2002) Quick guide: Target of rapamycin. Curr. Biol. 12(8), R269.
34. A. Sekulic, et al. (2000) A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells. Cancer Res. 60(13), 3504-3513.
35. P.B. Dennis, et al. (2001) Mammalian TOR: A homeostatic ATP sensor. Science 294(5544), 1102-1105.
36. S. Oldham, et al. (2000) Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes Dev. 14(21), 2689-2694.
37. D.J. Kwiatkowski, et al. (2002) A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol. Genet. 11(5), 525-534.
38. A. Jaeschke, et al. (2002) Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent. J. Cell Biol. 159(2), 217-224.
39. H.L. Kenerson, et al. (2002) Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. Cancer Res. 62(20), 5645-5650.
40. K. Inoki, et al. (2002) TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4(9), 648-657.
41. X. Gao, et al. (2002) Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat. Cell Biol. 4(9), 699-704.
42. B.D. Manning, et al. (2002) Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol. Cell 10(1), 151-162.
43. D. Avni, et al. (1994) Vertebrate mRNAs with a 5′-terminal pyrimidine tract are candidates for translation repression in quiescent cells. Characterization of the translational cis-regulatory element (TLRE). Mol. Cell. Biol. 14 3822-3833.
44. H.B.J. Jefferies, et al. (1994) Rapamycin selectively represses translation of the “polypyrimidine tract” mRNA family. Proc. Natl. Acad. Sci. USA 91 4441-4445.
45. H.B.J. Jefferies, et al. (1997) Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k. EMBO J. 12 3693-3704.
46. S. Fumagalli and G. Thomas (2000) S6 phosphorylation and signal transduction. N. Sonenberg, J.W.B. Hershey, M.B. Mathews,(Eds) Translational Control of Gene Expression Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
47. E.F. Blommaart, et al. (1995) Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270(5), 2320-2326.
48. P.O. Seglen and P. Bohley (1992) Autophagy and other vacuolar protein degradation mechanisms. Experientia 48(2), 158-172.
49. E.F. Blommaart, J.J. Luiken and A.J. Meijer (1997) Autophagic proteolysis: control and specificity. Histochem J. 29(5), 365-385.
50. N.T. Price, et al. (1991) Identification of the phosphorylation sites in elongation factor-2 from rabbit reticulocytes. FEBS Lett. 282(2), 253-258.
51. N.T. Redpath, E.J. Foulstone and C.G. Proud (1996) Regulation of translation elongation factor-2 by insulin via a rapamycin-sensitive signalling pathway. EMBO J. 15 2291-2297.
52. A.R. Saltiel and C.R. Kahn (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414(6865), 799-806.
53. Q. Wang, et al. (1999) Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Mol. Cell Biol. 19(6), 4008-4018.
54. K. Kotani, et al. (1998) Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes. Mol. Cell Biol. 18(12), 6971-6982.
55. S. Kristiansen, et al. (2001) GLUT-4 translocation in skeletal muscle studied with a cell-free assay: involvement of phospholipase D. Am. J. Physiol. Endocrinol. Metab. 281(3), E608-E618.
56. K. Gottlob, et al. (2001) Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev. 15(11), 1406-1418.
57. J. Deprez, et al. (2000) Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase. Biochem. J. 347(Pt 1), 305-312.
58. L. Bertrand, et al. (1999) Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B. J. Biol. Chem. 274(43), 30927-30933.
59. H.E. McDowell, P.A. Eyers and H.S. Hundal (1998) Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress. FEBS lett. 441(1), 15-19.
60. M. Munoz, J.H. Sweiry and G.E. Mann (1995) Insulin stimulates cationic amino acid transport activity in the isolated perfused rat pancreas. Exp. Physiol. 80(5), 745-753.
61. L.S. Jefferson and S.R. Kimball (2001) Amino acid regulation of gene expression. J. Nutr. 131(9 Suppl), 2460S-2466S. discussion 2486S–2487S
62. S.R. Kimball, et al. (1999) Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6. J. Biol. Chem. 274(17), 11647-11652.
63. T. Schmelzle and M.N. Hall (2000) TOR, a central controller of cell growth. Cell 103(2), 193-200.
64. A. Petiot, et al. (2000) Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macro-autophagy in HT-29 cells. J. Biol. Chem. 275(2), 992-998.
65. K. Shigemitsu, et al. (1999) Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells. J. Biol. Chem. 274(2), 1058-1065.
66. S. Arico, et al. (2001) The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J. Biol. Chem. 276(38), 35243-35246.