Stromelysin inhibitors designed from weakly bound fragments: Effects of linking and cooperativity

Journal of the American Chemical Society

Volumn 119, Issue 25, 1997, Pages 5828-5832

  Olejniczak, E T ^a   Hajduk, P J ^a   Marcotte, P A ^a   Nettesheim, D G ^a   Meadows, R P ^a   Edalji, R ^a   Holzman, T F ^a   Fesik, Stephen W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETOHYDROXAMIC ACID; MATRIX METALLOPROTEINASE; STROMELYSIN; STROMELYSIN INHIBITOR;

ARTICLE; CALORIMETRY; DRUG DETERMINATION; ENTHALPY; ENZYME MECHANISM; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE; TITRIMETRY;

EID: 0030829408     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9702780     Document Type: Article

References (19)

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