On the target of a novel class of antibiotics, oxazolidinones, active against multidrug-resistant Gram-positive bacteria

FEBS Letters

Volumn 425, Issue 1, 1998, Pages 40-44

  Burghardt, Helena ^a   Schimz, Karl Ludwig ^b   Müller, Matthias ^a,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Antibiotic; Gram positive bacterium; Oxazolidinone; Ribosomal subunit; Translation initiation

Indexed keywords

ANTIBIOTIC AGENT; N [[3 (4 ACETYLPHENYL) 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; OXAZOLIDINONE DERIVATIVE;

ARTICLE; DOSE RESPONSE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; RIBOSOME SUBUNIT; RNA BINDING; RNA TRANSLATION; TRANSLATION INITIATION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, MICROBIAL; DRUG RESISTANCE, MULTIPLE; ESCHERICHIA COLI; OXAZOLES; OXAZOLIDINONES; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; STAPHYLOCOCCUS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

EID: 0032549507     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)00194-X     Document Type: Article

References (18)

1. Slee A.M., Wuonola M.A., McRipley R.J., Zajac I., Zawada M.J., Bartholomew P.T., Gregory W.A., Forbes M. Antimicrob. Agents Chemother. 31:1987;1791-1797.
2. Ford C.W., Hamel J.C., Stapert D., Moerman J.K., Hutchinson D.K., Barbachyn M.R., Zurenko G.E. Trends Microbiol. 5:1997;196-200.
3. Eustice D.C., Feldman P.A., Slee A.M. Biochem. Biophys. Res. Commun. 150:1988;965-971.
4. Eustice D.C., Feldman P.A., Zajac I., Slee A.M. Antimicrob. Agents Chemother. 32:1988;1218-1222.
5. Götz F., Popp F., Korn E., Schleifer K.H. Nucleic Acids Res. 13:1985;5895-5906.
6. Schimz K.L., Decker G., Frings E., Meens J., Klein M., Müller M. FEBS Lett. 362:1995;29-33.
7. Helde R., Wieseler B., Wachter E., Neubüser A., Hoffschulte H.K., Hengelage T., Schimz K.L., Stuart R.A., Müller M. J. Bacteriol. 179:1997;4003-4012.
8. Hoffschulte H.K., Drees B., Müller M. J. Biol. Chem. 269:1994;12833-12839.
9. Müller M., Blobel G. Proc. Natl. Acad. Sci. USA. 81:1984;7421-7425.
10. Modolell J. Methods Enzymol. 30:1974;79-86.
11. La Teana A., Pon C.L., Gualerzi C.O. J. Mol. Biol. 256:1996;667-675.
12. Grunberg-Manago M., Clark B.F.C., Revel M., Rudland P.S., Dondon J. J. Mol. Biol. 40:1969;33-44.
13. Hershey J.W.B., Thach R.E. Proc. Natl. Acad. Sci. USA. 57:1967;759-766.
14. Gualerzi C.O., Pon C.L. Biochemistry. 29:1990;5881-5889.
15. Cundliffe, E. (1980) In: Ribosomes: Structure, Function, and Genetics (Chambliss, G. et al., Eds.), p. 555-581, University Park Press, Baltimore, MD.
16. Guérin M.F., Hayes D.H. Biochimie. 69:1987;965-974.
17. Lin A.H., Murray R.W., Vidmar T.J., Marotti K.R. Antimicrob. Agents Chemother. 41:1997;2127-2131.
18. Shinabarger D.L., Marotti K.R., Murray R.W., Lin A.H., Melchior E.P., Swaney S.M., Dunyak D.S., Demyan W.F., Buysse J.M. Antimicrob. Agents Chemother. 41:1997;2132-2136.