Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization

Journal of Cell Biology

Volumn 149, Issue 2, 2000, Pages 431-445

  Gilmore, Andrew P ^a   Metcalfe, Anthony D ^a   Romer, Lewis H ^b   Streuli, Charles H ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Adhesion; Apoptosis; Bax; Mammary; pp125FAK

Indexed keywords

CASPASE; EPITOPE; FOCAL ADHESION KINASE; INTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE P60;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CELL ADHESION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOL; EXTRACELLULAR MATRIX; FEMALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL ADHESION; CELL LINE; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; CYTOSOL; ENZYME INHIBITORS; FEMALE; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; INTEGRINS; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED ICR; POLYHYDROXYETHYL METHACRYLATE; PREGNANCY; PROTEIN CONFORMATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TRANSFECTION;

ANIMALIA;

EID: 0034678367     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.149.2.431     Document Type: Article

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