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Volumn 10, Issue 3, 1999, Pages 301-311

Positive selection as a developmental progression initiated by αβTCR signals that fix TCR specificity prior to lineage commitment

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD5 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

EID: 0033103765     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80030-8     Document Type: Article
Times cited : (27)

References (54)
  • 2
    • 0030218969 scopus 로고    scopus 로고
    • + maturation pathway in mouse thymic T cell development: Lineages and selection
    • + maturation pathway in mouse thymic T cell development: Lineages and selection. Immunity 5, 147-161.
    • (1996) Immunity , vol.5 , pp. 147-161
    • Akashi, K.1    Weissman, I.L.2
  • 3
    • 0032478068 scopus 로고    scopus 로고
    • Two distinct pathways of positive selection for thymocytes
    • Akashi, K., Kondo, M., and Weissman, I.L. (1998). Two distinct pathways of positive selection for thymocytes. Proc. Natl. Acad. Sci. USA 95, 2486-2491.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2486-2491
    • Akashi, K.1    Kondo, M.2    Weissman, I.L.3
  • 4
    • 0030737598 scopus 로고    scopus 로고
    • Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection
    • Anderson, G., Hare, K.J., Platt, N., and Jenkinson, E.J. (1997). Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection. Eur. J. Immunol. 27, 1838-1842.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1838-1842
    • Anderson, G.1    Hare, K.J.2    Platt, N.3    Jenkinson, E.J.4
  • 5
    • 0026078307 scopus 로고
    • Development of the CD4 and CD8 lineage of T cells: Instruction versus selection
    • Borgulya, P., Kishi, H., Muller, U., Kirberg, J., and von Boehmer, H. (1991). Development of the CD4 and CD8 lineage of T cells: Instruction versus selection. EMBO J. 10, 913-918.
    • (1991) EMBO J. , vol.10 , pp. 913-918
    • Borgulya, P.1    Kishi, H.2    Muller, U.3    Kirberg, J.4    Von Boehmer, H.5
  • 6
    • 0026721377 scopus 로고
    • Exclusion and inclusion of α and β T cell receptor alleles
    • Borgulya, P., Kishi, H., Uematsu, Y., and von Boehmer, H. (1992). Exclusion and inclusion of α and β T cell receptor alleles. Cell 69, 529-537.
    • (1992) Cell , vol.69 , pp. 529-537
    • Borgulya, P.1    Kishi, H.2    Uematsu, Y.3    Von Boehmer, H.4
  • 7
    • 0028107416 scopus 로고
    • Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection
    • Brandle, D., Muller, S., Muller, C., Hengartner, H., and Pircher, H. (1994). Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. Eur. J. Immunol. 24, 145-151.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 145-151
    • Brandle, D.1    Muller, S.2    Muller, C.3    Hengartner, H.4    Pircher, H.5
  • 8
    • 0027153897 scopus 로고
    • Another view of the selective model of thymocyte selection
    • Chan, S.H., Cosgrove, D., Waltzinger, C., Benoist, C., and Mathis, D. (1993). Another view of the selective model of thymocyte selection. Cell 73, 225-236.
    • (1993) Cell , vol.73 , pp. 225-236
    • Chan, S.H.1    Cosgrove, D.2    Waltzinger, C.3    Benoist, C.4    Mathis, D.5
  • 9
    • 0027266755 scopus 로고
    • Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes
    • Davis, C.B., Killeen, N., Crooks, M.E., Raulet, D., and Littman, D.R. (1993). Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes. Cell 73, 237-247.
    • (1993) Cell , vol.73 , pp. 237-247
    • Davis, C.B.1    Killeen, N.2    Crooks, M.E.3    Raulet, D.4    Littman, D.R.5
  • 10
  • 11
    • 85012710561 scopus 로고
    • Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors
    • Goldschneider, I., Komschlies, K.L., and Greiner, D.L. (1986). Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors. J. Exp. Med. 163, 1-17.
    • (1986) J. Exp. Med. , vol.163 , pp. 1-17
    • Goldschneider, I.1    Komschlies, K.L.2    Greiner, D.L.3
  • 12
    • 0027230682 scopus 로고
    • T cell receptor β chain dimers on immature thymocytes from normal mice
    • Groettrup, M., and von Boehmer, H. (1993). T cell receptor β chain dimers on immature thymocytes from normal mice. Eur. J. Immunol. 23, 1393-1396.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1393-1396
    • Groettrup, M.1    Von Boehmer, H.2
  • 13
    • 0027375004 scopus 로고
    • A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor β chain and a 33 kd glycoprotein
    • Groettrup, M., Ungewiss, K., Azogui, O., Palacios, R., Owen, M.J., Hayday, A.C., and von Boehmer, H. (1993). A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor β chain and a 33 kd glycoprotein. Cell 75, 283-294.
    • (1993) Cell , vol.75 , pp. 283-294
    • Groettrup, M.1    Ungewiss, K.2    Azogui, O.3    Palacios, R.4    Owen, M.J.5    Hayday, A.C.6    Von Boehmer, H.7
  • 16
    • 0025035509 scopus 로고
    • T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages
    • Guidos, C.J., Danska, J.S., Fathman, C.G., and Weissman, I.L. (1990). T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages. J. Exp. Med. 172, 835-845.
    • (1990) J. Exp. Med. , vol.172 , pp. 835-845
    • Guidos, C.J.1    Danska, J.S.2    Fathman, C.G.3    Weissman, I.L.4
  • 17
    • 0025933951 scopus 로고
    • Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
    • Huesmann, M., Scott, B., Kisielow, P., and von Boehmer, H. (1991). Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 66, 533-540.
    • (1991) Cell , vol.66 , pp. 533-540
    • Huesmann, M.1    Scott, B.2    Kisielow, P.3    Von Boehmer, H.4
  • 18
    • 0024288672 scopus 로고
    • T-cell development. Accessories or coreceptors?
    • Janeway, C.A., Jr. (1988). T-cell development. Accessories or coreceptors? Nature 335, 208-210.
    • (1988) Nature , vol.335 , pp. 208-210
    • Janeway C.A., Jr.1
  • 19
    • 0023837985 scopus 로고
    • Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex
    • Kappler, J.W., Staerz, U., White, J., and Marrack, P.C. (1988). Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature 332, 35-40.
    • (1988) Nature , vol.332 , pp. 35-40
    • Kappler, J.W.1    Staerz, U.2    White, J.3    Marrack, P.C.4
  • 20
    • 0028947844 scopus 로고
    • + thymocytes: Increased synthesis of TCR-α protein is an early response to TCR signaling that compensates for TCR-α instability, improves TCR assembly, and parallels other indicators of positive selection
    • + thymocytes: Increased synthesis of TCR-α protein is an early response to TCR signaling that compensates for TCR-α instability, improves TCR assembly, and parallels other indicators of positive selection. J. Exp. Med. 181, 193-202.
    • (1995) J. Exp. Med. , vol.181 , pp. 193-202
    • Kearse, K.P.1    Takahama, Y.2    Punt, J.A.3    Sharrow, S.O.4    Singer, A.5
  • 21
    • 0028872616 scopus 로고
    • Development and selection of T cells: Facts and puzzles
    • Kisielow, P., and von Boehmer, H. (1995). Development and selection of T cells: Facts and puzzles. Adv. Immunol. 58, 87-209.
    • (1995) Adv. Immunol. , vol.58 , pp. 87-209
    • Kisielow, P.1    Von Boehmer, H.2
  • 22
    • 0023683669 scopus 로고
    • Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
    • Kisielow, P., Teh, H.S., Bluthmann, H., and von Boehmer, H. (1988). Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 335, 730-733.
    • (1988) Nature , vol.335 , pp. 730-733
    • Kisielow, P.1    Teh, H.S.2    Bluthmann, H.3    Von Boehmer, H.4
  • 24
    • 0027509818 scopus 로고
    • Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3∈ determines clonal deletion or induction of developmental program
    • Levelt, C.N., Ehrfeld, A., and Eichmann, K. (1993). Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3∈ determines clonal deletion or induction of developmental program. J. Exp. Med. 177, 707-716.
    • (1993) J. Exp. Med. , vol.177 , pp. 707-716
    • Levelt, C.N.1    Ehrfeld, A.2    Eichmann, K.3
  • 25
    • 0027421675 scopus 로고
    • Normal sequence of phenotypic transitions in one cohort of 5-bromo-2′-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression
    • Lucas, B., Vasseur, F., and Penit, C. (1993). Normal sequence of phenotypic transitions in one cohort of 5-bromo-2′-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression. J. Immunol. 151, 4574-4582.
    • (1993) J. Immunol. , vol.151 , pp. 4574-4582
    • Lucas, B.1    Vasseur, F.2    Penit, C.3
  • 26
    • 0028354215 scopus 로고
    • Small cortical thymocytes are subject to positive selection
    • Lundberg, K., and Shortman, K. (1994). Small cortical thymocytes are subject to positive selection. J. Exp. Med. 179, 1475-1483.
    • (1994) J. Exp. Med. , vol.179 , pp. 1475-1483
    • Lundberg, K.1    Shortman, K.2
  • 28
    • 0028057579 scopus 로고
    • Generation of mature T cell populations in the thymus: CD4 or CD8 down-regulation occurs at different stages of thymocyte differentiation
    • Marodon, G., and Rocha, B. (1994). Generation of mature T cell populations in the thymus: CD4 or CD8 down-regulation occurs at different stages of thymocyte differentiation. Eur. J. Immunol. 24, 196-204.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 196-204
    • Marodon, G.1    Rocha, B.2
  • 29
    • 0030966756 scopus 로고    scopus 로고
    • Positive selection of thymocytes bearing αβ T cell receptors
    • Marrack, P., and Kappler, J. (1997). Positive selection of thymocytes bearing αβ T cell receptors. Curr. Opin. Immunol. 9, 250-255.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 250-255
    • Marrack, P.1    Kappler, J.2
  • 33
    • 0028467163 scopus 로고
    • An activated lck transgene promotes thymocyte development in RAG-1 mutant mice
    • Mombaerts, P., Anderson, S.J., Perlmutter, R.M., Mak, T.W., and Tonegawa, S. (1994). An activated lck transgene promotes thymocyte development in RAG-1 mutant mice. Immunity 1, 261-267.
    • (1994) Immunity , vol.1 , pp. 261-267
    • Mombaerts, P.1    Anderson, S.J.2    Perlmutter, R.M.3    Mak, T.W.4    Tonegawa, S.5
  • 35
    • 0027220211 scopus 로고
    • Multiple rearrangements in T cell receptor α chain genes maximize the production of useful thymocytes
    • Petrie, H.T., Livak, F., Schatz, D.G., Strasser, A., Crispe, I.N., and Shortman, K. (1993). Multiple rearrangements in T cell receptor α chain genes maximize the production of useful thymocytes. J. Exp. Med. 178, 615-622.
    • (1993) J. Exp. Med. , vol.178 , pp. 615-622
    • Petrie, H.T.1    Livak, F.2    Schatz, D.G.3    Strasser, A.4    Crispe, I.N.5    Shortman, K.6
  • 37
    • 0028201339 scopus 로고
    • Selective events in T cell development
    • Robey, E., and Fowlkes, B.J. (1994). Selective events in T cell development. Annu. Rev. Immunol. 12, 675-705.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 675-705
    • Robey, E.1    Fowlkes, B.J.2
  • 38
    • 0026034155 scopus 로고
    • Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
    • Robey, E.A., Fowlkes, B.J., Gordon, J.W., Kioussis, D., von Boehmer, H., Ramsdell, F., and Axel, R. (1991). Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage. Cell 64, 99-107.
    • (1991) Cell , vol.64 , pp. 99-107
    • Robey, E.A.1    Fowlkes, B.J.2    Gordon, J.W.3    Kioussis, D.4    Von Boehmer, H.5    Ramsdell, F.6    Axel, R.7
  • 40
    • 0024588554 scopus 로고
    • The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens
    • Scott, B., Bluthmann, H., Teh, H.S., and von Boehmer, H. (1989). The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens. Nature 338, 591-593.
    • (1989) Nature , vol.338 , pp. 591-593
    • Scott, B.1    Bluthmann, H.2    Teh, H.S.3    Von Boehmer, H.4
  • 42
    • 0027222868 scopus 로고
    • Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR β transgene
    • Shores, E.W., Nakayama, T., Wiest, D.L., Takahama, Y., Sharrow, S., and Singer, A. (1993). Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR β transgene. J. Immunol. 150, 1263-1275.
    • (1993) J. Immunol. , vol.150 , pp. 1263-1275
    • Shores, E.W.1    Nakayama, T.2    Wiest, D.L.3    Takahama, Y.4    Sharrow, S.5    Singer, A.6
  • 44
    • 0026030196 scopus 로고
    • ++ thymocytes as post- selection intermediates leading to mature T cells
    • ++ thymocytes as post- selection intermediates leading to mature T cells. J. Exp. Med. 173, 323-332.
    • (1991) J. Exp. Med. , vol.173 , pp. 323-332
    • Shortman, K.1    Vremec, D.2    Egerton, M.3
  • 45
    • 0003021556 scopus 로고
    • Role of self antigens in the selection of the developing T cell repertoire
    • B. Cinader and R.G. Miller, eds. (Orlando, California: Academic Press, Inc.)
    • Singer, A., Mizuochi, T., Munitz, T.I., and Gress, R.E. (1986). Role of self antigens in the selection of the developing T cell repertoire. In Progress in Immunology VI, B. Cinader and R.G. Miller, eds. (Orlando, California: Academic Press, Inc.), pp. 60-66.
    • (1986) Progress in Immunology VI , vol.6 , pp. 60-66
    • Singer, A.1    Mizuochi, T.2    Munitz, T.I.3    Gress, R.E.4
  • 46
    • 0028904213 scopus 로고
    • + T cell lineages: A new perspective on thymic commitment and selection
    • + T cell lineages: A new perspective on thymic commitment and selection. Immunity 2, 413-425.
    • (1995) Immunity , vol.2 , pp. 413-425
    • Suzuki, H.1    Punt, J.A.2    Granger, L.G.3    Singer, A.4
  • 48
    • 0027070358 scopus 로고
    • Post-transcriptional regulation of early T cell development by T cell receptor signals
    • Takahama, Y., and Singer, A. (1992). Post-transcriptional regulation of early T cell development by T cell receptor signals. Science 258, 1456-1462.
    • (1992) Science , vol.258 , pp. 1456-1462
    • Takahama, Y.1    Singer, A.2
  • 50
    • 0023813094 scopus 로고
    • Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells
    • Teh, H.S., Kisielow, P., Scott, B., Kishi, H., Uematsu, Y., Bluthmann, H., and von Boehmer, H. (1988). Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells. Nature 335, 229-233.
    • (1988) Nature , vol.335 , pp. 229-233
    • Teh, H.S.1    Kisielow, P.2    Scott, B.3    Kishi, H.4    Uematsu, Y.5    Bluthmann, H.6    Von Boehmer, H.7
  • 52
    • 0030963615 scopus 로고    scopus 로고
    • Structure and function of the pre-T cell receptor
    • von Boehmer, H., and Fehling, H.J. (1997). Structure and function of the pre-T cell receptor. Annu. Rev. Immunol. 15, 433-452.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 433-452
    • Von Boehmer, H.1    Fehling, H.J.2
  • 53
    • 0027329979 scopus 로고
    • Positive selection of immature αβ T cells
    • von Boehmer, H., Swat, W., and Kisielow, P. (1993). Positive selection of immature αβ T cells. Immunol. Rev. 135, 67-79.
    • (1993) Immunol. Rev. , vol.135 , pp. 67-79
    • Von Boehmer, H.1    Swat, W.2    Kisielow, P.3
  • 54
    • 0027427713 scopus 로고
    • CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection
    • Yamashita, I., Nagata, T., Tada, T., and Nakayama, T. (1993). CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection. Int. Immunol. 5, 1139-1150.
    • (1993) Int. Immunol. , vol.5 , pp. 1139-1150
    • Yamashita, I.1    Nagata, T.2    Tada, T.3    Nakayama, T.4


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