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Volumn 7, Issue 2, 2003, Pages 235-248

Targeting c-Myb expression in human disease

Author keywords

Antisense; Attenuation; c Myb c Myc; Clinical applications; Epithelial cancers; HIV; Oligodeoxynucleotides (ODNs); Phosphorothioate ODN; Therapy; Transcriptional pausing

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CISPLATIN; CYCLOOXYGENASE 2; LIPOSOME; MYC PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN C MYB;

EID: 0037396879     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.7.2.235     Document Type: Review
Times cited : (79)

References (92)
  • 1
    • 0034093722 scopus 로고    scopus 로고
    • Antisense therapeutics in chronic myeloid leukaemia: The promise, the progress and the problems
    • CLARK RE: Antisense therapeutics in chronic myeloid leukaemia: the promise, the progress and the problems. Leukemia (2000) 14:347-355.
    • (2000) Leukemia , vol.14 , pp. 347-355
    • Clark, R.E.1
  • 2
    • 0022110525 scopus 로고
    • Nucleotide sequence of cDNA clones of the murine myb proto-oncogene
    • GONDA TJ, GOUGH NM, DUNN AR, DE BLAQUIERE J: Nucleotide sequence of cDNA clones of the murine myb proto-oncogene. EMBO J. (1985) 4:2003-2008.
    • (1985) EMBO J. , vol.4 , pp. 2003-2008
    • Gonda, T.J.1    Gough, N.M.2    Dunn, A.R.3    De Blaquiere, J.4
  • 4
    • 0031888616 scopus 로고    scopus 로고
    • Myb proteins in life, death and differentiation
    • WESTON K: Myb proteins in life, death and differentiation. Curr. Opin. Genet. Dev. (1998) 8:76-81.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 76-81
    • Weston, K.1
  • 5
    • 0033551375 scopus 로고    scopus 로고
    • Myb binding proteins: Regulators and cohorts in transformation
    • NESS SA: Myb binding proteins: regulators and cohorts in transformation. Oncogene (1999) 18:3039-3046.
    • (1999) Oncogene , vol.18 , pp. 3039-3046
    • Ness, S.A.1
  • 6
    • 0020463955 scopus 로고
    • Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene
    • KLEMPNAUER KH, GONDA TJ, BISHOP JM: Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: the architecture of a transduced oncogene. Cell (1982) 31:453-463.
    • (1982) Cell , vol.31 , pp. 453-463
    • Klempnauer, K.H.1    Gonda, T.J.2    Bishop, J.M.3
  • 7
    • 0343458031 scopus 로고
    • Expression of cellular homologues of retroviral onc genes in human hematopoietic cells
    • WESTIN EH, WONG-STAAL F, GELMANN EP et al.: Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proc. Natl. Acad. Sci. USA (1982) 79:2490-2494.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 2490-2494
    • Westin, E.H.1    Wong-Staal, F.2    Gelmann, E.P.3
  • 8
    • 0022373045 scopus 로고
    • Developmental regulation of c-myb in normal myeloid progenitor cells
    • DUPREY SP, BOETTIGER D: Developmental regulation of c-myb in normal myeloid progenitor cells. Proc. Natl. Acad. Sci. USA (1985) 82:6937-6941.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 6937-6941
    • Duprey, S.P.1    Boettiger, D.2
  • 9
    • 0031015205 scopus 로고    scopus 로고
    • Constitutive expression of full-length c-Myb transforms avian cells characteristic of both the monocytic and granulocytic lineages
    • FU SL, LIPSICK JS: Constitutive expression of full-length c-Myb transforms avian cells characteristic of both the monocytic and granulocytic lineages. Cell Growth Differ. (1997) 8:35-45.
    • (1997) Cell Growth Differ. , vol.8 , pp. 35-45
    • Fu, S.L.1    Lipsick, J.S.2
  • 10
    • 0024456711 scopus 로고
    • Murine myeloid cell lines derived by in vitro infection with recombinant c-myb retroviruses express myb from rearranged vector proviruses
    • GONDA TJ, RAMSAY RG, JOHNSON GR: Murine myeloid cell lines derived by in vitro infection with recombinant c-myb retroviruses express myb from rearranged vector proviruses. EMBO J. (1989) 8:1767-1775.
    • (1989) EMBO J. , vol.8 , pp. 1767-1775
    • Gonda, T.J.1    Ramsay, R.G.2    Johnson, G.R.3
  • 11
    • 0024469060 scopus 로고
    • Activation of c-myb by carboxy-terminal truncation: Relationship to transformation of murine haemopoietic cells in vitro
    • GONDA TJ, BUCKMASTER C, RAMSAY RG: Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro. EMBO J. (1989) 8:1777-1783.
    • (1989) EMBO J. , vol.8 , pp. 1777-1783
    • Gonda, T.J.1    Buckmaster, C.2    Ramsay, R.G.3
  • 12
    • 0025821494 scopus 로고
    • A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
    • MUCENSKI ML, MCLAIN K, KIER AB et al.: A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell (1991) 65:677-689.
    • (1991) Cell , vol.65 , pp. 677-689
    • Mucenski, M.L.1    McLain, K.2    Kier, A.B.3
  • 14
    • 0032534074 scopus 로고    scopus 로고
    • c-Myb down-regulation is associated with human colon cell differentiation, apoptosis, and decreased Bcl-2 expression
    • THOMPSON MA, ROSENTHAL MA, ELLIS SL et al.: c-Myb down-regulation is associated with human colon cell differentiation, apoptosis, and decreased Bcl-2 expression. Cancer Res. (1998) 58:5168-5175.
    • (1998) Cancer Res. , vol.58 , pp. 5168-5175
    • Thompson, M.A.1    Rosenthal, M.A.2    Ellis, S.L.3
  • 15
    • 0026593217 scopus 로고
    • Oncogene alterations in rat colon tumors induced by N-methyl-N-nitrosourea
    • ALEXANDER RJ, BUXBAUM JN, RAICHT RF: Oncogene alterations in rat colon tumors induced by N-methyl-N-nitrosourea. Am. J. Med. Sci. (1992) 303:16-24.
    • (1992) Am. J. Med. Sci. , vol.303 , pp. 16-24
    • Alexander, R.J.1    Buxbaum, J.N.2    Raicht, R.F.3
  • 17
    • 0033554590 scopus 로고    scopus 로고
    • c-Myb is critical for murine colon development
    • ZORBAS M, SICURELLA C, BERTONCELLO I et al.: c-Myb is critical for murine colon development. Oncogene (1999) 18:5821-5830.
    • (1999) Oncogene , vol.18 , pp. 5821-5830
    • Zorbas, M.1    Sicurella, C.2    Bertoncello, I.3
  • 18
    • 0029278720 scopus 로고
    • Myb: An old oncoprotein with new roles
    • THOMPSON MA, RAMSAY RG: Myb: an old oncoprotein with new roles. Bioessays (1995) 17:341-350.
    • (1995) Bioessays , vol.17 , pp. 341-350
    • Thompson, M.A.1    Ramsay, R.G.2
  • 19
    • 0025830266 scopus 로고
    • Inhibition of proliferation by c-myb antisense oligodeoxynucleotides in colon adenocarcinoma cell lines that express c-myb
    • MELANI C, RIVOLTINI L, PARMIANI G, CALABRETTA B, COLOMBO MP: Inhibition of proliferation by c-myb antisense oligodeoxynucleotides in colon adenocarcinoma cell lines that express c-myb. Cancer Res. (1991) 51:2897-2901.
    • (1991) Cancer Res. , vol.51 , pp. 2897-2901
    • Melani, C.1    Rivoltini, L.2    Parmiani, G.3    Calabretta, B.4    Colombo, M.P.5
  • 20
    • 0026939036 scopus 로고
    • Myb expression is higher in malignant human colonic carcinoma and premalignant adenomatous polyps than in normal mucosa
    • RAMSAY RG, THOMPSON MA, HAYMAN JA, REID G, GONDA TJ, WHITEHEAD RH: Myb expression is higher in malignant human colonic carcinoma and premalignant adenomatous polyps than in normal mucosa. Cell Growth Differ. (1992) 3:723-730.
    • (1992) Cell Growth Differ. , vol.3 , pp. 723-730
    • Ramsay, R.G.1    Thompson, M.A.2    Hayman, J.A.3    Reid, G.4    Gonda, T.J.5    Whitehead, R.H.6
  • 21
    • 0035070327 scopus 로고    scopus 로고
    • c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: Clinical and experimental findings
    • BIROCCIO A, BENASSI B, D'AGNANO I et al.:c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings. Am. J. Pathol. (2001) 158:1289-1299.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1289-1299
    • Biroccio, A.1    Benassi, B.2    D'Agnano, I.3
  • 22
    • 0035887459 scopus 로고    scopus 로고
    • Molecular classification of human carcinomas by use of gene expression signatures
    • SU AI, WELSH JB, SAPINOSO LM et al.: Molecular classification of human carcinomas by use of gene expression signatures. Cancer Res. (2001) 61:7388-7393.
    • (2001) Cancer Res. , vol.61 , pp. 7388-7393
    • Su, A.I.1    Welsh, J.B.2    Sapinoso, L.M.3
  • 23
    • 0033835810 scopus 로고    scopus 로고
    • Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells
    • JOHNSTONE CN, TEBBUTT NC, ABUD HE, et al.: Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. (2000) 279:G500-G510.
    • (2000) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.279
    • Johnstone, C.N.1    Tebbutt, N.C.2    Abud, H.E.3
  • 24
    • 0025174653 scopus 로고
    • Strong: Association between c-myb and oestrogen-receptor expression in human breast cancer
    • GUERIN M, SHENG ZM, ANDRIEU N, RIOU G: Strong association between c-myb and oestrogen-receptor expression in human breast cancer. Oncogene (1990) 5:131-135.
    • (1990) Oncogene , vol.5 , pp. 131-135
    • Guerin, M.1    Sheng, Z.M.2    Andrieu, N.3    Riou, G.4
  • 25
    • 0034307159 scopus 로고    scopus 로고
    • MYB oncogene amplification in hereditary BRCA1 breast cancer
    • KAURANIEMI P, HEDENFALK I, PERSSON K et al.: MYB oncogene amplification in hereditary BRCA1 breast cancer. Cancer Res. (2000) 60:5323-5328.
    • (2000) Cancer Res. , vol.60 , pp. 5323-5328
    • Kauraniemi, P.1    Hedenfalk, I.2    Persson, K.3
  • 26
    • 0025848916 scopus 로고
    • Enhanced expression of oncogene-encoded mRNA in rat model of colon cancer
    • ALEXANDER RJ, BUXBAUM JN, RAICHT RF: Enhanced expression of oncogene-encoded mRNA in rat model of colon cancer. Am. J. Med. Sci. (1991) 301:238-245.
    • (1991) Am. J. Med. Sci. , vol.301 , pp. 238-245
    • Alexander, R.J.1    Buxbaum, J.N.2    Raicht, R.F.3
  • 27
    • 0030001801 scopus 로고    scopus 로고
    • Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease
    • ALEXANDER RJ, PANJA A, KAPLAN-LISS E, MAYER L, RAICHT RF: Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease. Dig. Dis. Sci. (1996) 41:660-669.
    • (1996) Dig. Dis. Sci. , vol.41 , pp. 660-669
    • Alexander, R.J.1    Panja, A.2    Kaplan-Liss, E.3    Mayer, L.4    Raicht, R.F.5
  • 29
    • 0034901012 scopus 로고    scopus 로고
    • Increased c-myb mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma
    • BRABENDER J, LORD RV, DANENBERG KD et al.: Increased c-myb mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma. J. Surg. Res. (2001) 99:301-306.
    • (2001) J. Surg. Res. , vol.99 , pp. 301-306
    • Brabender, J.1    Lord, R.V.2    Danenberg, K.D.3
  • 30
    • 0026527835 scopus 로고
    • Defective c-myc and c-myb RNA turnover in acute myeloid leukemia cells
    • BAER MR, AUGUSTINOS P, KINNIBURGH AJ: Defective c-myc and c-myb RNA turnover in acute myeloid leukemia cells. Blood (1992) 79:1319-1326.
    • (1992) Blood , vol.79 , pp. 1319-1326
    • Baer, M.R.1    Augustinos, P.2    Kinniburgh, A.J.3
  • 31
    • 0030940856 scopus 로고    scopus 로고
    • Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines
    • THOMPSON MA, FLEGG R, WESTIN EH, RAMSAY RG: Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines. Oncogene (1997) 14:1715-1723.
    • (1997) Oncogene , vol.14 , pp. 1715-1723
    • Thompson, M.A.1    Flegg, R.2    Westin, E.H.3    Ramsay, R.G.4
  • 32
    • 0026350675 scopus 로고
    • Sequence requirements for premature transcription arrest within the first intron of the mouse c-fos gene
    • MECHTI N, PIECHACZYK M, BLANCHARD JM, JEANTEUR P, LEBLEU B: Sequence requirements for premature transcription arrest within the first intron of the mouse c-fos gene. Mol. Cell. Biol. (1991) 11:2832-2841.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 2832-2841
    • Mechti, N.1    Piechaczyk, M.2    Blanchard, J.M.3    Jeanteur, P.4    Lebleu, B.5
  • 33
    • 0033179498 scopus 로고    scopus 로고
    • Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes
    • KEENE RG, MUELLER A, LANDICK R, LONDON L: Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes. Nucleic Acids Res. (1999) 27:3173-3182.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 3173-3182
    • Keene, R.G.1    Mueller, A.2    Landick, R.3    London, L.4
  • 34
    • 0028823364 scopus 로고
    • Loss of transcriptional attenuation in N-myc is associated with progression towards a more malignant phenotype
    • XU L, MENG Y, WALLEN R, DEPINHO RA: Loss of transcriptional attenuation in N-myc is associated with progression towards a more malignant phenotype. Oncogene (1995) 11:1865-1872.
    • (1995) Oncogene , vol.11 , pp. 1865-1872
    • Xu, L.1    Meng, Y.2    Wallen, R.3    Depinho, R.A.4
  • 35
    • 0033745127 scopus 로고    scopus 로고
    • Biomarkers of human colonic cell growth are influenced differently by a history of colonic neoplasia and the consumption of acarbose
    • WEAVER GA, TANGEL CT, KRAUSE JA et al.: Biomarkers of human colonic cell growth are influenced differently by a history of colonic neoplasia and the consumption of acarbose. J. Nutr. (2000) 130:2718-2725.
    • (2000) J. Nutr. , vol.130 , pp. 2718-2725
    • Weaver, G.A.1    Tangel, C.T.2    Krause, J.A.3
  • 36
    • 0033367018 scopus 로고    scopus 로고
    • Chemoprevention of carcinogen-induced mammary tumorigenesis by the hybrid polar cytodifferentiation agent, suberanilohydroxamic acid (SAHA)
    • COHEN LA, AMIN S, MARKS PA, RIFKIND RA, DESAI D, RICHON VM: Chemoprevention of carcinogen-induced mammary tumorigenesis by the hybrid polar cytodifferentiation agent, suberanilohydroxamic acid (SAHA). Anticancer Res. (1999) 19:4999-5005.
    • (1999) Anticancer Res. , vol.19 , pp. 4999-5005
    • Cohen, L.A.1    Amin, S.2    Marks, P.A.3    Rifkind, R.A.4    Desai, D.5    Richon, V.M.6
  • 37
    • 0029844212 scopus 로고    scopus 로고
    • v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells
    • FRAMPTON J, RAMQVIST T, GRAF T: v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells. Genes Dev. (1996) 10:2720-2731.
    • (1996) Genes Dev. , vol.10 , pp. 2720-2731
    • Frampton, J.1    Ramqvist, T.2    Graf, T.3
  • 38
    • 0029824846 scopus 로고    scopus 로고
    • A dominant interfering Myb mutant causes apoptosis in T cells
    • TAYLOR D, BADIANI P, WESTON K: A dominant interfering Myb mutant causes apoptosis in T cells. Genes Dev. (1996) 10:2732-2744.
    • (1996) Genes Dev. , vol.10 , pp. 2732-2744
    • Taylor, D.1    Badiani, P.2    Weston, K.3
  • 39
    • 0027154047 scopus 로고
    • Mechanism of c-myc regulation by c-Myb in different cell lineages
    • COGSWELL JP, COGSWELL PC, KUEHL WM et al.: Mechanism of c-myc regulation by c-Myb in different cell lineages. Mol. Cell. Biol. (1993) 13:2858-2869.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2858-2869
    • Cogswell, J.P.1    Cogswell, P.C.2    Kuehl, W.M.3
  • 40
    • 0026511139 scopus 로고
    • Transcriptional activation of the c-myc gene by the c-myb and B-myb gene products
    • NAKAGOSHI H, KANEI-ISHII C, SAWAZAKI T, MIZUGUCHI G, ISHII S: Transcriptional activation of the c-myc gene by the c-myb and B-myb gene products. Oncogene (1992) 7:1233-1240.
    • (1992) Oncogene , vol.7 , pp. 1233-1240
    • Nakagoshi, H.1    Kanei-ishii, C.2    Sawazaki, T.3    Mizuguchi, G.4    Ishii, S.5
  • 41
    • 0033993632 scopus 로고    scopus 로고
    • Regulation of the resident chromosomal copy of the c-myc by c-Myb is involved in myeloid leukemogenesis
    • SCHMIDT M, NAZAROV V, STEVENS L, WATSON R, WOLFF L: Regulation of the resident chromosomal copy of the c-myc by c-Myb is involved in myeloid leukemogenesis. Mol. Cell. Biol. (2000) 20:1970-1981.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1970-1981
    • Schmidt, M.1    Nazarov, V.2    Stevens, L.3    Watson, R.4    Wolff, L.5
  • 42
    • 0034032244 scopus 로고    scopus 로고
    • Cyclooxygenase-2,: A colorectal cancer nonsteroidal anti-inflammatory drug target, is regulated by c-MYB
    • RAMSAY RG, FRIEND A, VIZANTIOS Y et al.: Cyclooxygenase-2, a colorectal cancer nonsteroidal anti-inflammatory drug target, is regulated by c-MYB. Cancer Res. (2000) 60:1805-1809.
    • (2000) Cancer Res. , vol.60 , pp. 1805-1809
    • Ramsay, R.G.1    Friend, A.2    Vizantios, Y.3
  • 44
    • 0025166027 scopus 로고
    • Myb protein binds to human repeat (LTR) sequences and long terminal LTR-mediated transcription
    • DASGUPTA P, SAIKUMAR P, REDDY CD, REDDY EP: Myb protein binds to human repeat (LTR) sequences and long terminal LTR-mediated transcription. Proc. Natl. Acad. Sci. USA (1990) 87:8090-8094.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8090-8094
    • Dasgupta, P.1    Saikumar, P.2    Reddy, C.D.3    Reddy, E.P.4
  • 47
    • 0027331858 scopus 로고
    • The myc family of oncogenes and their presence and importance in small-cell lung carcinoma and other tumour types
    • PRINS J, DE VRIES EG, MULDER NH: The myc family of oncogenes and their presence and importance in small-cell lung carcinoma and other tumour types. Anticancer Res. (1993) 13:1373-1385.
    • (1993) Anticancer Res. , vol.13 , pp. 1373-1385
    • Prins, J.1    Devries, E.G.2    Mulder, N.H.3
  • 48
    • 0027416659 scopus 로고
    • Chimeric oligodeoxynucleotide analogues: Enhanced cell uptake of structures which direct ribonuclease H with high specificity
    • GILES RV, SPILLER DG, TIDD DM: Chimeric oligodeoxynucleotide analogues: enhanced cell uptake of structures which direct ribonuclease H with high specificity. Anticancer Drug Des. (1993) 8:33-51.
    • (1993) Anticancer Drug Des. , vol.8 , pp. 33-51
    • Giles, R.V.1    Spiller, D.G.2    Tidd, D.M.3
  • 49
    • 0032147234 scopus 로고    scopus 로고
    • Nucleic acid therapeutic: State of the art and future prospects
    • GEWIRTZ AM, SOKOL DL, RATZCZAK MZ: Nucleic acid therapeutic: state of the art and future prospects. Blood (1998) 92:712-736.
    • (1998) Blood , vol.92 , pp. 712-736
    • Gewirtz, A.M.1    Sokol, D.L.2    Ratzczak, M.Z.3
  • 50
    • 0034798245 scopus 로고    scopus 로고
    • The experimental use of antisense oligonucleotides: A guide for the perplexed
    • STEIN CA: The experimental use of antisense oligonucleotides: a guide for the perplexed. J. Clin. Invest. (2001) 108:641-644.
    • (2001) J. Clin. Invest. , vol.108 , pp. 641-644
    • Stein, C.A.1
  • 51
    • 14744277298 scopus 로고
    • Oligonucleoside methylphosphonates as antisense reagents
    • MILLER PS: Oligonucleoside methylphosphonates as antisense reagents. Biotechnology (NY) (1991) 9:358-362.
    • (1991) Biotechnology (NY) , vol.9 , pp. 358-362
    • Miller, P.S.1
  • 52
    • 0032699477 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: The case for an RNase H-independent structural type
    • 1489
    • SUMMERTON J: Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim. Biophys. Acta (1999) 1489:141-158.
    • (1999) Biochim. Biophys. Acta , pp. 141-158
    • Summerton, J.1
  • 53
    • 0026737456 scopus 로고
    • Anti-sense oligodeoxynucleotides - Promises and pitfalls
    • STEIN CA: Anti-sense oligodeoxynucleotides - promises and pitfalls. Leukemia (1992) 6:967-974.
    • (1992) Leukemia , vol.6 , pp. 967-974
    • Stein, C.A.1
  • 54
    • 0024296609 scopus 로고
    • Physicochemical properties of phosphorothioate oligodeoxynucleotides
    • STEIN CA, SUBASINGHE C, SHINOZUKA K, COHEN JS: Physicochemical properties of phosphorothioate oligodeoxynucleotides. Nucleic Acids Res. (1988) 16:3209-3221.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 3209-3221
    • Stein, C.A.1    Subasinghe, C.2    Shinozuka, K.3    Cohen, J.S.4
  • 55
    • 0023447274 scopus 로고
    • Phosphorothioate analogs of oligodeoxynucleotides: Inhibitors of replication and cytopathic effects of human immunodeficiency virus
    • MATSUKURA M, SHINOZUKA K, ZON G et al.: Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA (1987) 84:7706-7710.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7706-7710
    • Matsukura, M.1    Shinozuka, K.2    Zon, G.3
  • 56
    • 0027492473 scopus 로고
    • Cellular pharmacology of phosphorothioate homooligodeoxynucleotides in human cells
    • GAO WY, STORM C, EGAN W, CHENG YC: Cellular pharmacology of phosphorothioate homooligodeoxynucleotides in human cells. Mol. Pharmacol. (1993) 43:45-50.
    • (1993) Mol. Pharmacol. , vol.43 , pp. 45-50
    • Gao, W.Y.1    Storm, C.2    Egan, W.3    Cheng, Y.C.4
  • 57
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents-is the bullet really magical?
    • STEIN CA, CHENG YC: Antisense oligonucleotides as therapeutic agents-is the bullet really magical? Science (1993) 261:1004-1012.
    • (1993) Science , vol.261 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.C.2
  • 58
    • 0026009971 scopus 로고
    • Interactions of antisense DNA oligonucleotide analogs with phospholipid membranes (liposomes)
    • AKHTAR S, BASU S, WICKSTROM E, JULIANO RL: Interactions of antisense DNA oligonucleotide analogs with phospholipid membranes (liposomes). Nucleic Acids Res. (1991) 19:5551-5559.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5551-5559
    • Akhtar, S.1    Basu, S.2    Wickstrom, E.3    Juliano, R.L.4
  • 59
    • 0027092897 scopus 로고
    • Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
    • BENNETT CF, CHIANG MY, CHAN H, SHOEMAKER JE, MIRABELLI CK: Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. (1992) 41:1023-1033.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 1023-1033
    • Bennett, C.F.1    Chiang, M.Y.2    Chan, H.3    Shoemaker, J.E.4    Mirabelli, C.K.5
  • 60
    • 0027459559 scopus 로고
    • Use of an antisense oligonucleotide to inhibit expression of a mutated human procollagen gene (COL1A1) in transfected mouse 3T3 cells
    • COLIGE A, SOKOLOV BP, NUGENT P, BASERGA R, PROCKOP DJ: Use of an antisense oligonucleotide to inhibit expression of a mutated human procollagen gene (COL1A1) in transfected mouse 3T3 cells. Biochemistry (1993) 32:7-11.
    • (1993) Biochemistry , vol.32 , pp. 7-11
    • Colige, A.1    Sokolov, B.P.2    Nugent, P.3    Baserga, R.4    Prockop, D.J.5
  • 61
    • 0032007293 scopus 로고    scopus 로고
    • Oligodeoxyribonucleotide uptake in primary human hematopoietic cells is enhanced by cationic lipids and depends on the hematopoietic cell subset
    • KRONENWETT R, STEIDL U, KIRSCH M, SCZAKIEL G, HAAS R: Oligodeoxyribonucleotide uptake in primary human hematopoietic cells is enhanced by cationic lipids and depends on the hematopoietic cell subset. Blood (1998) 91:852-862.
    • (1998) Blood , vol.91 , pp. 852-862
    • Kronenwett, R.1    Steidl, U.2    Kirsch, M.3    Sczakiel, G.4    Haas, R.5
  • 62
    • 0030922755 scopus 로고    scopus 로고
    • Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: Potential mechanism of action
    • HENRY SP, GICLAS PC, LEEDS J et al.: Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: potential mechanism of action. J. Pharmacol. Exp. Ther. (1997) 281:810-816.
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 810-816
    • Henry, S.P.1    Giclas, P.C.2    Leeds, J.3
  • 63
    • 0030888664 scopus 로고    scopus 로고
    • BCL-2 antisense therapy in patients with non-Hodgkin lymphoma
    • WEBB A, CUNNINGHAM D, COTTER F et al.: BCL-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet (1997) 349:1137-1141.
    • (1997) Lancet , vol.349 , pp. 1137-1141
    • Webb, A.1    Cunningham, D.2    Cotter, F.3
  • 64
    • 0033977066 scopus 로고    scopus 로고
    • A new liposomal formulation for antisense oligodeoxynucleotides with small size, high incorporation efficiency and good stability
    • 1463
    • STUART DD, ALLEN TM: A new liposomal formulation for antisense oligodeoxynucleotides with small size, high incorporation efficiency and good stability. Biochim. Biophys. Acta (2000) 1463:219-229.
    • (2000) Biochim. Biophys. Acta , pp. 219-229
    • Stuart, D.D.1    Allen, T.M.2
  • 65
    • 0029949266 scopus 로고    scopus 로고
    • Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
    • XU Y, SZOKA FC Jr: Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry (1996) 35:5616-5623.
    • (1996) Biochemistry , vol.35 , pp. 5616-5623
    • Xu, Y.1    Szoka F.C., Jr.2
  • 66
    • 0028114572 scopus 로고
    • Patterns of intracellular compartmentalization, trafficking and acidification of 5′-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells
    • TONKINSON JL, STEIN CA: Patterns of intracellular compartmentalization, trafficking and acidification of 5′-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells. Nucleic Acids Res. (1994) 22:4268-4275.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4268-4275
    • Tonkinson, J.L.1    Stein, C.A.2
  • 67
    • 0029964866 scopus 로고    scopus 로고
    • Mechanism of oligonucleotide release from cationic liposomes
    • ZELPHATI O, SZOKA FC Jr: Mechanism of oligonucleotide release from cationic liposomes. Proc. Natl. Acad. Sci. USA (1996) 93:11493-11498.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11493-11498
    • Zelphati, O.1    Szoka F.C., Jr.2
  • 68
    • 0029001621 scopus 로고
    • The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism
    • BURGESS TL, FISHER EF, ROSS SL et al.: The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism. Proc. Natl. Acad. Sci. USA (1995) 92:4051-4055.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4051-4055
    • Burgess, T.L.1    Fisher, E.F.2    Ross, S.L.3
  • 69
    • 0031051928 scopus 로고    scopus 로고
    • Contiguous four-guanosine sequence in c-myc antisense phosphorothioate oligonucleotides inhibits cell growth on human lung cancer cells: Possible involvement of cell adhesion inhibition
    • SAIJO Y, UCHIYAMA B, ABE T, SATOH K, NUKIWA T: Contiguous four-guanosine sequence in c-myc antisense phosphorothioate oligonucleotides inhibits cell growth on human lung cancer cells: possible involvement of cell adhesion inhibition. Jpn. J. Cancer Res. (1997) 88:26-33.
    • (1997) Jpn. J. Cancer Res. , vol.88 , pp. 26-33
    • Saijo, Y.1    Uchiyama, B.2    Abe, T.3    Satoh, K.4    Nukiwa, T.5
  • 70
    • 0030789137 scopus 로고    scopus 로고
    • Formation of a G-tetrad and higher order structures correlates with biological activity of the RelA (NF-κB p65) 'antisense' oligodeoxynucleotide
    • BENIMETSKAYA L, BERTON M, KOLBANOVSKY A, BENIMETSKY S, STEIN CA: Formation of a G-tetrad and higher order structures correlates with biological activity of the RelA (NF-κB p65) 'antisense' oligodeoxynucleotide. Nucleic Acids Res. (1997) 25:2648-2656.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2648-2656
    • Benimetskaya, L.1    Berton, M.2    Kolbanovsky, A.3    Benimetsky, S.4    Stein, C.A.5
  • 71
    • 0026625208 scopus 로고
    • Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN [correction of INF] and augment IFN-mediated [correction of INF] natural killer activity
    • YAMAMOTO S, YAMAMOTO T, KATAOKA T, KURAMOTO E, YANO O, TOKUNAGA T: Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN [correction of INF] and augment IFN-mediated [correction of INF] natural killer activity. J. Immunol. (1992) 148:4072-4076.
    • (1992) J. Immunol. , vol.148 , pp. 4072-4076
    • Yamamoto, S.1    Yamamoto, T.2    Kataoka, T.3    Kuramoto, E.4    Yano, O.5    Tokunaga, T.6
  • 72
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B-cell activation
    • KRIEG AM, YI AK, MATSON S et al.: CpG motifs in bacterial DNA trigger direct B-cell activation. Nature (1995) 374:546-549.
    • (1995) Nature , vol.374 , pp. 546-549
    • Krieg, A.M.1    Yi, A.K.2    Matson, S.3
  • 73
    • 0029811432 scopus 로고    scopus 로고
    • Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs
    • KRIEG AM, MATSON S, FISHER E: Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs. Antisense Nucleic Acid Drug Dev. (1996) 6:133-139.
    • (1996) Antisense Nucleic Acid Drug Dev. , vol.6 , pp. 133-139
    • Krieg, A.M.1    Matson, S.2    Fisher, E.3
  • 74
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
    • NEURATH MF, PETTERSSON S, MEYER ZUM BUSCHENFELDE KH, STROBER W: Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nat. Med. (1996) 2:998-1004.
    • (1996) Nat. Med. , vol.2 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer Zum Buschenfelde, K.H.3    Strober, W.4
  • 75
    • 9344237152 scopus 로고    scopus 로고
    • Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo
    • DEL BUFALO D, CUCCO C, LEONETTI C et al.: Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo. Br. J. Cancer (1996) 74:387-393.
    • (1996) Br. J. Cancer , vol.74 , pp. 387-393
    • Del Bufalo, D.1    Cucco, C.2    Leonetti, C.3
  • 77
    • 0029977448 scopus 로고    scopus 로고
    • Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
    • MONIA BP, JOHNSTON JF, GEIGER T, MULLER M, FABBRO D: Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat. Med. (1996) 2:668-675.
    • (1996) Nat. Med. , vol.2 , pp. 668-675
    • Monia, B.P.1    Johnston, J.F.2    Geiger, T.3    Muller, M.4    Fabbro, D.5
  • 78
    • 0027528518 scopus 로고
    • In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides
    • OFFENSPERGER WB, OFFENSPERGER S, WALTER E et al.: In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides. EMBO J. (1993) 12:1257-1262.
    • (1993) EMBO J. , vol.12 , pp. 1257-1262
    • Offensperger, W.B.1    Offensperger, S.2    Walter, E.3
  • 80
    • 0033056726 scopus 로고    scopus 로고
    • Oligonucleotides as inhibitors of human immunodeficiency virus
    • FIELD AK: Oligonucleotides as inhibitors of human immunodeficiency virus. Curr. Opin. Mol. Ther. (1999) 1:323-331.
    • (1999) Curr. Opin. Mol. Ther. , vol.1 , pp. 323-331
    • Field, A.K.1
  • 82
    • 0027729703 scopus 로고
    • Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a Phase I trial
    • BAYEVER E, IVERSEN PL, BISHOP MR et al.: Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a Phase I trial. Antisense Res. Dev. (1993) 3:383-390.
    • (1993) Antisense Res. Dev. , vol.3 , pp. 383-390
    • Bayever, E.1    Iversen, P.L.2    Bishop, M.R.3
  • 83
    • 0037082474 scopus 로고    scopus 로고
    • Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: A pilot study
    • LUGER SM, O'BRIEN SG, RATAJCZAK J et al.: Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: a pilot study. Blood (2002) 99:1150-1158.
    • (2002) Blood , vol.99 , pp. 1150-1158
    • Luger, S.M.1    O'Brien, S.G.2    Ratajczak, J.3
  • 84
    • 0035406511 scopus 로고    scopus 로고
    • Use of c-myb antisense oligonucleotides to increase the sensitivity of human colon cancer cells to cisplatin
    • FUNATO T, SATOU J, KOZAWA K, FUJIMAKI S, MIURA T, KAKU M: Use of c-myb antisense oligonucleotides to increase the sensitivity of human colon cancer cells to cisplatin. Oncol. Rep. (2001) 8:807-810.
    • (2001) Oncol. Rep. , vol.8 , pp. 807-810
    • Funato, T.1    Satou, J.2    Kozawa, K.3    Fujimaki, S.4    Miura, T.5    Kaku, M.6
  • 85
    • 0033508430 scopus 로고    scopus 로고
    • Distinct cellular factors regulate the c-myb promoter through its E2F element
    • CAMPANERO MR, ARMSTRONG M, FLEMINGTON E: Distinct cellular factors regulate the c-myb promoter through its E2F element. Mol. Cell. Biol. (1999) 19:8442-8450.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8442-8450
    • Campanero, M.R.1    Armstrong, M.2    Flemington, E.3
  • 86
    • 0023268971 scopus 로고
    • Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation
    • BENDER TP, THOMPSON CB, KUEHL WM: Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation. Science (1987) 237:1473-1476.
    • (1987) Science , vol.237 , pp. 1473-1476
    • Bender, T.P.1    Thompson, C.B.2    Kuehl, W.M.3
  • 87
    • 0023857363 scopus 로고
    • A transcriptional arrest mechanism involved in controlling constitutive levels of mouse c-myb mRNA
    • WATSON RJ: A transcriptional arrest mechanism involved in controlling constitutive levels of mouse c-myb mRNA. Oncogene (1988) 2:267-272.
    • (1988) Oncogene , vol.2 , pp. 267-272
    • Watson, R.J.1
  • 88
    • 0026848846 scopus 로고
    • Human therapeutics based on triple helix technology
    • CHUBB JM, HOGAN ME: Human therapeutics based on triple helix technology. Trends Biotech. (1992) 10:132-136.
    • (1992) Trends Biotech. , vol.10 , pp. 132-136
    • Chubb, J.M.1    Hogan, M.E.2
  • 89
    • 0029262020 scopus 로고
    • Antisense approaches to cancer gene therapy
    • MERCOLA D, COHEN JS: Antisense approaches to cancer gene therapy. Cancer Gene Ther. (1995) 2:47-59.
    • (1995) Cancer Gene Ther. , vol.2 , pp. 47-59
    • Mercola, D.1    Cohen, J.S.2
  • 90
    • 0030862707 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: Design, preparation, and properties
    • SUMMERTON J, WELLER D: Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev. (1997) 7:187-195.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 187-195
    • Summerton, J.1    Weller, D.2
  • 91
    • 0035900635 scopus 로고    scopus 로고
    • A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst
    • NISHIKURA K: A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst. Cell (2001) 107:415-418.
    • (2001) Cell , vol.107 , pp. 415-418
    • Nishikura, K.1


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