MYB oncogene amplification in hereditary BRCA1 breast cancer

Cancer Research

Volumn 60, Issue 19, 2000, Pages 5323-5328

  Kauraniemi, P ^a   Hedenfalk, I ^a   Persson, K ^a   Duggan, D J ^a   Tanner, M ^a   Johannsson, O ^a   Olsson, H ^a   Trent, J M ^a   Isola, J ^a   Borg, A ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREAST CANCER; CANCER GROWTH; CHROMOSOME 6Q; CHROMOSOME LOSS; FAMILIAL CANCER; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; ONCOGENE; PRIORITY JOURNAL;

BLOTTING, NORTHERN; BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 6; DNA, COMPLEMENTARY; DNA, NEOPLASM; GENE AMPLIFICATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; GENES, MYB; GERM-LINE MUTATION; HUMAN; IN SITU HYBRIDIZATION, FLUORESCENCE; NUCLEIC ACID HYBRIDIZATION; ONCOGENE PROTEINS V-MYB; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T;

EID: 0034307159     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Distinct somatic genetic changes associated with rumor progression in carriers of BRCA1 and BRCA2 germ-line mutations
2. Insights into the functions of BRCA1 and BRCA2
3. Cancer-susceptibility genes. Gatekeepers and caretakers
4. Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer
5. Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer
6. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
7. Use of a cDNA microarray to analyse gene expression patterns in human cancer
8. Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays
9. Ratio-based decisions and the quantitative analysis of cDNA microarray images
10. Characterization of a high copy number amplification at 6q24 in pancreatic cancer identifies c-myb as a candidate oncogene
11. Specificity of proto-oncogene amplification in human malignant diseases
12. Amplification of the c-myb oncogene in a case of human acute myelogenous leukemia
13. Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma
14. The Myb oncoprotein: Regulating a regulator
15. The myb oncogene family of transcription factors: Potent regulators of hematopoietic cell proliferation and differentiation
16. Constitutive expression of B-myb can bypass p53-induced Waf1/Cip1-mediated G1 arrest
17. Arrest of spermatogenesis and defective breast development in mice lacking A-myb
18. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
19. Drosophila myb is required for the G2/M transition and maintenance of diploidy
20. The Schizosaccharomyces pombe cdc5+ gene encodes an essential protein with homology to c-Myb
21. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
22. Posttranscriptional regulation of the c-myb proto-oncogene in estrogen receptor-positive breast cancer cells
23. Strong association between c-myb and oestrogen-receptor expression in human breast cancer
24. Tumour biological features of BRCA1-induced breast and ovarian cancer
25. Allelotype of human breast carcinoma: A second major site for loss of heterozygosity is on chromosome 6q