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Volumn 23, Issue 4, 2003, Pages 514-525

The hypothalamic-pituitary-adrenal axis and low-dose glucocorticoids in the treatment of septic shock

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLUTETHIMIDE; ANTICOAGULANT AGENT; DOPAMINE; DROTRECOGIN; ETOMIDATE; FLUDROCORTISONE; GLUCOCORTICOID; HYDROCORTISONE; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; KETOCONAZOLE; METHYLPREDNISOLONE; NONSTEROID ANTIINFLAMMATORY AGENT; NORADRENALIN; PHENOBARBITAL; PHENYTOIN; PLACEBO; RIFAMPICIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0037380501     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.23.4.514.32123     Document Type: Review
Times cited : (8)

References (136)
  • 1
    • 0026710191 scopus 로고
    • American College of Chest Physicians/Society of Critical Care Medicine consensus conference: Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • Bone RC, Balk RA, Cerra FB, et al. American College of Chest Physicians/Society of Critical Care Medicine consensus conference: definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992;101:1644-55.
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3
  • 3
    • 0033590515 scopus 로고    scopus 로고
    • Treating patients with severe sepsis
    • Wheeler AP, Bernard GR. Treating patients with severe sepsis. N Engl J Med 1999;340:207-14.
    • (1999) N Engl J Med , vol.340 , pp. 207-214
    • Wheeler, A.P.1    Bernard, G.R.2
  • 4
    • 0032433470 scopus 로고    scopus 로고
    • Has the mortality of septic shock changed with time?
    • Friedman G, Silva E, Vincent JL. Has the mortality of septic shock changed with time? Crit Care Med 1998;26:2078-86.
    • (1998) Crit Care Med , vol.26 , pp. 2078-2086
    • Friedman, G.1    Silva, E.2    Vincent, J.L.3
  • 5
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29:1303-10.
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 6
    • 0026016470 scopus 로고
    • Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin: A randomized, double-blind, placebo-controlled trial
    • Ziegler EJ, Fisher CH, Sprung CL, Straube RC, Sadoff JC, Foulke GE. Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin: a randomized, double-blind, placebo-controlled trial. N Engl J Med 1991;324:429-36.
    • (1991) N Engl J Med , vol.324 , pp. 429-436
    • Ziegler, E.J.1    Fisher, C.H.2    Sprung, C.L.3    Straube, R.C.4    Sadoff, J.C.5    Foulke, G.E.6
  • 7
    • 0028557981 scopus 로고
    • Treatment of septic shock with human monoclonal antibody HA-1A: A randomized, double-blind, placebo-controlled trial
    • McCloskey RV, Straube RC, Sanders C, Smith SM, Smith CR. Treatment of septic shock with human monoclonal antibody HA-1A: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1994;121:1-5.
    • (1994) Ann Intern Med , vol.121 , pp. 1-5
    • McCloskey, R.V.1    Straube, R.C.2    Sanders, C.3    Smith, S.M.4    Smith, C.R.5
  • 8
    • 0029043636 scopus 로고
    • A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial
    • Bone RC, Balk RA, Fein AM, et al. A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. Crit Care Med 1995;23:994-1006.
    • (1995) Crit Care Med , vol.23 , pp. 994-1006
    • Bone, R.C.1    Balk, R.A.2    Fein, A.M.3
  • 9
    • 0027945044 scopus 로고
    • Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: A randomized, double-blind, placebo-controlled, multicenter clinical trial
    • Dhainaut JF, Tenaillon A, Le Tulzo Y. Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. Crit Care Med 1994;22:1720-8.
    • (1994) Crit Care Med , vol.22 , pp. 1720-1728
    • Dhainaut, J.F.1    Tenaillon, A.2    Le Tulzo, Y.3
  • 10
    • 0028239555 scopus 로고
    • Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome: Results from a randomized, double-blind, placebo-controlled trial
    • Fisher CJJ, Dhainaut JF, Opal SM, et al. Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome: results from a randomized, double-blind, placebo-controlled trial. JAMA 1994;271:1836-43.
    • (1994) JAMA , vol.271 , pp. 1836-1843
    • Fisher, C.J.J.1    Dhainaut, J.F.2    Opal, S.M.3
  • 11
    • 0030877935 scopus 로고    scopus 로고
    • Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, double-blind, placebo-controlled, multicenter trial
    • Opal SM, Fisher CJJ, Dhainaut JF, et al. Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. Crit Care Med 1997;25:1115-24.
    • (1997) Crit Care Med , vol.25 , pp. 1115-1124
    • Opal, S.M.1    Fisher, C.J.J.2    Dhainaut, J.F.3
  • 12
    • 0028018567 scopus 로고
    • Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: A randomized, open-label, placebo-controlled multicenter trial
    • Fisher CJJ, Slotman GJ, Opal SM, et al. Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial. Crit Care Med 1994;22:12-21.
    • (1994) Crit Care Med , vol.22 , pp. 12-21
    • Fisher, C.J.J.1    Slotman, G.J.2    Opal, S.M.3
  • 13
    • 0028957549 scopus 로고
    • Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome: A randomized, controlled, double-blind, multicenter clinical trial
    • Abraham E, Wunderink R, Silverman H, et al. Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome: a randomized, controlled, double-blind, multicenter clinical trial. JAMA 1995;273:934-41.
    • (1995) JAMA , vol.273 , pp. 934-941
    • Abraham, E.1    Wunderink, R.2    Silverman, H.3
  • 14
    • 0029835023 scopus 로고    scopus 로고
    • Intersept: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis
    • Cohen J, Carlet J. INTERSEPT: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis. Crit Care Med 1996;24:1431-40.
    • (1996) Crit Care Med , vol.24 , pp. 1431-1440
    • Cohen, J.1    Carlet, J.2
  • 15
    • 8244235133 scopus 로고    scopus 로고
    • p55 Tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock: A randomized, controlled, multicenter trial
    • Abraham E, Glauser M, Butler T, et al. p55 Tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock: a randomized, controlled, multicenter trial. JAMA 1997;277:1531-8.
    • (1997) JAMA , vol.277 , pp. 1531-1538
    • Abraham, E.1    Glauser, M.2    Butler, T.3
  • 16
    • 0032495658 scopus 로고    scopus 로고
    • Double-blind randomised controlled trial of monoclonal antibody to human tumor necrosis factor in treatment of septic shock
    • Abraham E, Anzueto A, Gutierrez G, et al. Double-blind randomised controlled trial of monoclonal antibody to human tumor necrosis factor in treatment of septic shock. Lancet 1998;351:929-33.
    • (1998) Lancet , vol.351 , pp. 929-933
    • Abraham, E.1    Anzueto, A.2    Gutierrez, G.3
  • 17
    • 0035100346 scopus 로고    scopus 로고
    • Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: A randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients
    • Abraham E, Laterre PF, Garbino J, et al. Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients. Crit Care Med 2001;29:503-10.
    • (2001) Crit Care Med , vol.29 , pp. 503-510
    • Abraham, E.1    Laterre, P.F.2    Garbino, J.3
  • 18
    • 0029900294 scopus 로고    scopus 로고
    • Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein
    • Fisher CJJ, Agosti JM, Opal SM, et al. Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. N Engl J Med 1996;334:1697-702.
    • (1996) N Engl J Med , vol.334 , pp. 1697-1702
    • Fisher, C.J.J.1    Agosti, J.M.2    Opal, S.M.3
  • 19
    • 0035046049 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES study
    • Reinhart K, Menges T, Gardlund B, et al. Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: the RAMSES study. Crit Care Med 2001;29:765-9.
    • (2001) Crit Care Med , vol.29 , pp. 765-769
    • Reinhart, K.1    Menges, T.2    Gardlund, B.3
  • 20
    • 0035826096 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344:699-709.
    • (2001) N Engl J Med , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.2    Laterre, P.F.3
  • 21
    • 0035159740 scopus 로고    scopus 로고
    • Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study
    • Abraham E, Reinhart K, Svoboda P, et al. Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: a multicenter, randomized, placebo-controlled, single-blind, dose escalation study. Crit Care Med 2001;29:2081-9.
    • (2001) Crit Care Med , vol.29 , pp. 2081-2089
    • Abraham, E.1    Reinhart, K.2    Svoboda, P.3
  • 22
    • 8044246571 scopus 로고    scopus 로고
    • The effects of ibuprofen on the physiology and survival of patients with sepsis: The ibuprofen in sepsis study group
    • Bernard GR, Wheeler AP, Russell JA, et al. The effects of ibuprofen on the physiology and survival of patients with sepsis: the ibuprofen in sepsis study group. N Engl J Med 1997:912-18.
    • (1997) N Engl J Med , pp. 912-918
    • Bernard, G.R.1    Wheeler, A.P.2    Russell, J.A.3
  • 23
    • 0023252009 scopus 로고
    • A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock
    • Bone RC, Fisher CJ, Clemmer TP, Slotman GJ, Metz CA, Balk RA. A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med 1987;317:653-8.
    • (1987) N Engl J Med , vol.317 , pp. 653-658
    • Bone, R.C.1    Fisher, C.J.2    Clemmer, T.P.3    Slotman, G.J.4    Metz, C.A.5    Balk, R.A.6
  • 24
    • 0029090390 scopus 로고
    • Corticosteroid treatment for sepsis: A critical appraisal and meta-analysis of the literature
    • Cronin L, Cook DJ, Carlet J, et al. Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature. Crit Care Med 1995;23:1430-9.
    • (1995) Crit Care Med , vol.23 , pp. 1430-1439
    • Cronin, L.1    Cook, D.J.2    Carlet, J.3
  • 25
    • 0029036182 scopus 로고
    • Steroid controversy in sepsis and septic shock: A meta-analysis
    • Lefering R, Neugebauer EA. Steroid controversy in sepsis and septic shock: a meta-analysis. Crit Care Med 1995;23:1294-303.
    • (1995) Crit Care Med , vol.23 , pp. 1294-1303
    • Lefering, R.1    Neugebauer, E.A.2
  • 26
    • 0023239471 scopus 로고
    • Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis
    • Veterans Administration Systemic Sepsis Cooperative Study Group. Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N Engl J Med 1987;317:659-65.
    • (1987) N Engl J Med , vol.317 , pp. 659-665
  • 27
    • 0032962833 scopus 로고    scopus 로고
    • Sepsis research: We must change course
    • Nasraway SA. Sepsis research: we must change course. Crit Care Med 1999;27:427-30.
    • (1999) Crit Care Med , vol.27 , pp. 427-430
    • Nasraway, S.A.1
  • 28
    • 0031026648 scopus 로고    scopus 로고
    • Vasopressin deficiency contributes to the vasodilation of septic shock
    • Landry DW, Levin HR, Gallant EM, et al. Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation 1997;95:1122-5.
    • (1997) Circulation , vol.95 , pp. 1122-1125
    • Landry, D.W.1    Levin, H.R.2    Gallant, E.M.3
  • 29
    • 0035109135 scopus 로고    scopus 로고
    • Hemodynamic and metabolic effects of low-dose vasopressin infusions in vasodilatory septic shock
    • Tsuneyoshi I, Yamada H, Kakihana Y, Nakamura M, Nakano Y, Boyle WA. Hemodynamic and metabolic effects of low-dose vasopressin infusions in vasodilatory septic shock. Crit Care Med 2001;29:487-93.
    • (2001) Crit Care Med , vol.29 , pp. 487-493
    • Tsuneyoshi, I.1    Yamada, H.2    Kakihana, Y.3    Nakamura, M.4    Nakano, Y.5    Boyle, W.A.6
  • 30
    • 84873766246 scopus 로고
    • Effect of cortisone on acute streptococcal infections and post-streptococcal complications
    • Hahn EO, Houser HB, Rammelkamp CH. Effect of cortisone on acute streptococcal infections and post-streptococcal complications. J Clin Invest 1951;30:274-81.
    • (1951) J Clin Invest , vol.30 , pp. 274-281
    • Hahn, E.O.1    Houser, H.B.2    Rammelkamp, C.H.3
  • 32
    • 0017064383 scopus 로고
    • Steroids in the treatment of clinical septic shock
    • Schumer W. Steroids in the treatment of clinical septic shock. Ann Surg 1976;184:333-41.
    • (1976) Ann Surg , vol.184 , pp. 333-341
    • Schumer, W.1
  • 33
    • 0023778758 scopus 로고
    • Dexamethasone therapy for bacterial meningitis: Results of two double-blind, placebo-controlled trials
    • Lebel MH, Freij BJ, Syrogiannopoulos GA, et al. Dexamethasone therapy for bacterial meningitis: results of two double-blind, placebo-controlled trials. N Engl J Med 1988;319:964-71.
    • (1988) N Engl J Med , vol.319 , pp. 964-971
    • Lebel, M.H.1    Freij, B.J.2    Syrogiannopoulos, G.A.3
  • 34
    • 0025876403 scopus 로고
    • The beneficial effects of early dexamethasone administration in infants and children with bacterial meningitis
    • Odio CM, Faingezicht I, Paris M, et al. The beneficial effects of early dexamethasone administration in infants and children with bacterial meningitis. N Engl J Med 1991;324:1525-31.
    • (1991) N Engl J Med , vol.324 , pp. 1525-1531
    • Odio, C.M.1    Faingezicht, I.2    Paris, M.3
  • 35
    • 0025324166 scopus 로고
    • Corticosteroids prevent early deterioration in patients with moderately severe Pneumocystis carinii pneumonia and the acquired immunodeficiency syndrome (AIDS)
    • Montaner JS, Lawson LM, Levitt N, Belzberg A, Schechter MT, Ruedy J. Corticosteroids prevent early deterioration in patients with moderately severe Pneumocystis carinii pneumonia and the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1990;113:14-20.
    • (1990) Ann Intern Med , vol.113 , pp. 14-20
    • Montaner, J.S.1    Lawson, L.M.2    Levitt, N.3    Belzberg, A.4    Schechter, M.T.5    Ruedy, J.6
  • 36
    • 0025144705 scopus 로고
    • Corticosteroids as adjunctive therapy for severe Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome: A double-blind, placebo-controlled trial
    • Gagnon S, Boota AM, Fischl MA, Baier H, Kirksey OW, La Voie L. Corticosteroids as adjunctive therapy for severe Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome: a double-blind, placebo-controlled trial. N Engl J Med 1990;323:1444-50.
    • (1990) N Engl J Med , vol.323 , pp. 1444-1450
    • Gagnon, S.1    Boota, A.M.2    Fischl, M.A.3    Baier, H.4    Kirksey, O.W.5    La Voie, L.6
  • 37
    • 0028879316 scopus 로고
    • Plasma and BAL cytokine response to corticosteroid rescue treatment in late ARDS
    • Meduri GU, Headley S, Tolley E, Shelby M, Stentz F, Postlethwaite A. Plasma and BAL cytokine response to corticosteroid rescue treatment in late ARDS. Chest 1995;108:1315-25.
    • (1995) Chest , vol.108 , pp. 1315-1325
    • Meduri, G.U.1    Headley, S.2    Tolley, E.3    Shelby, M.4    Stentz, F.5    Postlethwaite, A.6
  • 39
    • 0034536736 scopus 로고    scopus 로고
    • Hydrocortisone and the reduction of vasopressors in septic shock: Therapy or only chart cosmetics
    • Briegel J. Hydrocortisone and the reduction of vasopressors in septic shock: therapy or only chart cosmetics. Intensive Care Med 2000;26:1723-6.
    • (2000) Intensive Care Med , vol.26 , pp. 1723-1726
    • Briegel, J.1
  • 40
    • 0032946372 scopus 로고    scopus 로고
    • Stress doses of hydrocortisone to reverse hyperdynamic septic shock: A prospective, randomized, double-blind, single-center study
    • Briegel J, Forst H, Haller M, et al. Stress doses of hydrocortisone to reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med 1999;27:723-32.
    • (1999) Crit Care Med , vol.27 , pp. 723-732
    • Briegel, J.1    Forst, H.2    Haller, M.3
  • 41
    • 0034026201 scopus 로고    scopus 로고
    • Stress doses of glucocorticoids in catecholamine dependency: A new therapy for a new syndrome
    • Bollaert PE. Stress doses of glucocorticoids in catecholamine dependency: a new therapy for a new syndrome. Intensive Care Med 2000;26:3-5.
    • (2000) Intensive Care Med , vol.26 , pp. 3-5
    • Bollaert, P.E.1
  • 42
    • 0031894232 scopus 로고    scopus 로고
    • Corticosteroids in septic shock: Resurrection of last rites
    • Matot I, Sprung CL. Corticosteroids in septic shock: resurrection of last rites. Crit Care Med 1998;26:627-30.
    • (1998) Crit Care Med , vol.26 , pp. 627-630
    • Matot, I.1    Sprung, C.L.2
  • 43
    • 0031919533 scopus 로고    scopus 로고
    • Glucocorticoid treatment of sepsis and acute respiratory distress syndrome: Time for reappraisal
    • Meduri GU, Kanangat S. Glucocorticoid treatment of sepsis and acute respiratory distress syndrome: time for reappraisal. Crit Care Med 1998;26:630-3.
    • (1998) Crit Care Med , vol.26 , pp. 630-633
    • Meduri, G.U.1    Kanangat, S.2
  • 44
    • 0025915582 scopus 로고
    • Contribution of cortisol deficiency to septic shock
    • Briegel J, Forst H, Hellinger H, Haller M. Contribution of cortisol deficiency to septic shock. Lancet 1991;338:507-8.
    • (1991) Lancet , vol.338 , pp. 507-508
    • Briegel, J.1    Forst, H.2    Hellinger, H.3    Haller, M.4
  • 45
    • 0032939037 scopus 로고    scopus 로고
    • From mega to more reasonable doses of corticosteroids: A decade to recreate hope
    • Carlet J. From mega to more reasonable doses of corticosteroids: a decade to recreate hope. Crit Care Med 1999;27:672-4.
    • (1999) Crit Care Med , vol.27 , pp. 672-674
    • Carlet, J.1
  • 46
    • 0033398206 scopus 로고    scopus 로고
    • New rationale for glucocorticoid treatment in septic shock
    • Meduri GU. New rationale for glucocorticoid treatment in septic shock. J Chemother 1999;11:541-50.
    • (1999) J Chemother , vol.11 , pp. 541-550
    • Meduri, G.U.1
  • 47
    • 0030016074 scopus 로고    scopus 로고
    • Are endogenous glucocorticoid levels adequate in septic shock?
    • Annane D, Raphael JC, Gajdos P. Are endogenous glucocorticoid levels adequate in septic shock? Intensive Care Med 1996;22:711-12.
    • (1996) Intensive Care Med , vol.22 , pp. 711-712
    • Annane, D.1    Raphael, J.C.2    Gajdos, P.3
  • 48
    • 0029889310 scopus 로고    scopus 로고
    • Steroid replacement in sepsis: An unexplored side of a multifaceted drug class
    • Annane D, Raphael JC, Gajdos P. Steroid replacement in sepsis: an unexplored side of a multifaceted drug class. Crit Care Med 1996;24:899-900.
    • (1996) Crit Care Med , vol.24 , pp. 899-900
    • Annane, D.1    Raphael, J.C.2    Gajdos, P.3
  • 49
    • 0031867469 scopus 로고    scopus 로고
    • Duration of glucocorticoid treatment and outcome in sepsis: Is the right drug used the wrong way?
    • Meduri GU, Chrousos GP. Duration of glucocorticoid treatment and outcome in sepsis: is the right drug used the wrong way? Chest 1998;114:355-60.
    • (1998) Chest , vol.114 , pp. 355-360
    • Meduri, G.U.1    Chrousos, G.P.2
  • 50
    • 0037151571 scopus 로고    scopus 로고
    • Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
    • Annane D, Sébile V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002;288:862-71.
    • (2002) JAMA , vol.288 , pp. 862-871
    • Annane, D.1    Sébile, V.2    Charpentier, C.3
  • 51
    • 0029037126 scopus 로고
    • The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
    • Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 1995;20:1351-62.
    • (1995) N Engl J Med , vol.20 , pp. 1351-1362
    • Chrousos, G.P.1
  • 55
    • 0035116763 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal insufficiency
    • Zaloga GP, Marik P. Hypothalamic-pituitary-adrenal insufficiency. Crit Care Clin 2001;17:25-41.
    • (2001) Crit Care Clin , vol.17 , pp. 25-41
    • Zaloga, G.P.1    Marik, P.2
  • 56
    • 0034754254 scopus 로고    scopus 로고
    • Patterns of cortisol-binding globulin and the free cortisol index during septic shock and multitrauma
    • Beishuizen A, Thijs LG, Vermes I. Patterns of cortisol-binding globulin and the free cortisol index during septic shock and multitrauma. Intensive Care Med 2001;27:1584-91.
    • (2001) Intensive Care Med , vol.27 , pp. 1584-1591
    • Beishuizen, A.1    Thijs, L.G.2    Vermes, I.3
  • 57
    • 0028903509 scopus 로고
    • Corticosteroid effect on early beta-adrenergic down-regulation during circulatory shock: Hemodynamic study and beta-adrenergic receptor assay
    • Saito T, Takanashi M, Gallagher E, et al. Corticosteroid effect on early beta-adrenergic down-regulation during circulatory shock: hemodynamic study and beta-adrenergic receptor assay. Intensive Care Med 1995;21:204-10.
    • (1995) Intensive Care Med , vol.21 , pp. 204-210
    • Saito, T.1    Takanashi, M.2    Gallagher, E.3
  • 58
    • 0030122536 scopus 로고    scopus 로고
    • The effect of methylprednisolone on myocardial beta-adrenergic receptors and cardiovascular function in shock patients
    • Saito T, Fuse A, Gallagher ET, et al. The effect of methylprednisolone on myocardial beta-adrenergic receptors and cardiovascular function in shock patients. Shock 1996;5:241-6.
    • (1996) Shock , vol.5 , pp. 241-246
    • Saito, T.1    Fuse, A.2    Gallagher, E.T.3
  • 60
    • 0037045443 scopus 로고    scopus 로고
    • Corticosteroid supplementation for adrenal insufficiency
    • Coursin DB, Wood KE. Corticosteroid supplementation for adrenal insufficiency JAMA 2002;287:236-40.
    • (2002) JAMA , vol.287 , pp. 236-240
    • Coursin, D.B.1    Wood, K.E.2
  • 63
    • 0023263030 scopus 로고
    • Spectrum of serum cortisol response to ACTH in ICU patients: Correlation with degree of illness and mortality
    • Jurney TH, Cockrell JL, Lindberg JS, Lamiell JM, Wade CE. Spectrum of serum cortisol response to ACTH in ICU patients: correlation with degree of illness and mortality. Chest 1987;92:292-5.
    • (1987) Chest , vol.92 , pp. 292-295
    • Jurney, T.H.1    Cockrell, J.L.2    Lindberg, J.S.3    Lamiell, J.M.4    Wade, C.E.5
  • 64
    • 0342980285 scopus 로고    scopus 로고
    • A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin
    • Annane D, Sébille V, Troché G, Raphaël JC, Gajdos P, Bellissant E. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA 2000;283:1038-45.
    • (2000) JAMA , vol.283 , pp. 1038-1045
    • Annane, D.1    Sébille, V.2    Troché, G.3    Raphaël, J.C.4    Gajdos, P.5    Bellissant, E.6
  • 65
    • 0026754132 scopus 로고
    • Adrenocortical function: An indicator of severity of disease and survival in chronic critically ill patients
    • Span LF, Hermus ARM, Bartelink AKM, et al. Adrenocortical function: an indicator of severity of disease and survival in chronic critically ill patients. Intensive Care Med 1992;18:93-6.
    • (1992) Intensive Care Med , vol.18 , pp. 93-96
    • Span, L.F.1    Hermus, A.R.M.2    Bartelink, A.K.M.3
  • 66
    • 0030591713 scopus 로고    scopus 로고
    • Adrenal insufficiency
    • Oelkers W. Adrenal insufficiency. N Engl J Med 1996;335:1206-12.
    • (1996) N Engl J Med , vol.335 , pp. 1206-1212
    • Oelkers, W.1
  • 67
    • 0035100693 scopus 로고    scopus 로고
    • Adrenal insufficiency during the late stage of polymicrobial sepsis
    • Koo DJ, Jackman D, Chaudry IH, Wang P. Adrenal insufficiency during the late stage of polymicrobial sepsis. Crit Care Med 2001;29:618-22.
    • (2001) Crit Care Med , vol.29 , pp. 618-622
    • Koo, D.J.1    Jackman, D.2    Chaudry, I.H.3    Wang, P.4
  • 68
    • 0035113369 scopus 로고    scopus 로고
    • The hypothalamic-pituitary-adrenal axis of patients with severe sepsis: Altered response to corticotropin-releasing hormone
    • Schroeder S, Wichers M, Klingmüller D, et al. The hypothalamic-pituitary-adrenal axis of patients with severe sepsis: altered response to corticotropin-releasing hormone. Crit Care Med 2001;29:310-16.
    • (2001) Crit Care Med , vol.29 , pp. 310-316
    • Schroeder, S.1    Wichers, M.2    Klingmüller, D.3
  • 69
    • 0028906714 scopus 로고
    • Adrenal insufficiency occurring during septic shock: Incidence, outcome, and relationship to peripheral cytokine levels
    • Soni A, Pepper GM, Wyrwinski PM, et al. Adrenal insufficiency occurring during septic shock: incidence, outcome, and relationship to peripheral cytokine levels. Am J Med 1995;98:266-71.
    • (1995) Am J Med , vol.98 , pp. 266-271
    • Soni, A.1    Pepper, G.M.2    Wyrwinski, P.M.3
  • 70
    • 0029823003 scopus 로고    scopus 로고
    • A comparison of the adrenocortical response during septic shock and after complete recovery
    • Briegel J, Schelling G, Haller M, Mraz W, Forst H, Peter K. A comparison of the adrenocortical response during septic shock and after complete recovery. Intensive Care Med 1996;22:894-9.
    • (1996) Intensive Care Med , vol.22 , pp. 894-899
    • Briegel, J.1    Schelling, G.2    Haller, M.3    Mraz, W.4    Forst, H.5    Peter, K.6
  • 71
    • 0025974325 scopus 로고
    • Cortisol response to corticotropin and survival in septic shock
    • Rothwell PM, Udwadia ZF, Lawler PG. Cortisol response to corticotropin and survival in septic shock. Lancet 1991;337:582-3.
    • (1991) Lancet , vol.337 , pp. 582-583
    • Rothwell, P.M.1    Udwadia, Z.F.2    Lawler, P.G.3
  • 72
    • 0033756918 scopus 로고    scopus 로고
    • Endocrine and metabolic responses in children with meningococcal sepsis: Striking differences between survivors and nonsurvivors
    • Joosten KFM, De Kleijn ED, Westerterp M, et al. Endocrine and metabolic responses in children with meningococcal sepsis: striking differences between survivors and nonsurvivors. J Clin Endocrinol Metab 2000;85:3746-53.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3746-3753
    • Joosten, K.F.M.1    De Kleijn, E.D.2    Westerterp, M.3
  • 73
    • 0035892933 scopus 로고    scopus 로고
    • Adrenocorticotropic hormone and cortisol levels in relation to inflammatory response and disease severity in children with meningococcal disease
    • van Woensel JBM, Biezeveld MH, Biesterbos Alders AM, et al. Adrenocorticotropic hormone and cortisol levels in relation to inflammatory response and disease severity in children with meningococcal disease. J Infect Dis 2001;184:1532-7.
    • (2001) J Infect Dis , vol.184 , pp. 1532-1537
    • Van Woensel, J.B.M.1    Biezeveld, M.H.2    Biesterbos Alders, A.M.3
  • 74
    • 0348242049 scopus 로고    scopus 로고
    • Comparison of low-dose (1 μg) with conventional-dose cosyntropin (250 μg) for adrenal insufficiency testing in critical illness
    • Yamashita S, Drynan J, Guest C, Silverberg J. Comparison of low-dose (1 μg) with conventional-dose cosyntropin (250 μg) for adrenal insufficiency testing in critical illness [abstr]. Crit Care Med 2001;29(suppl):A164.
    • (2001) Crit Care Med , vol.29 , Issue.SUPPL.
    • Yamashita, S.1    Drynan, J.2    Guest, C.3    Silverberg, J.4
  • 75
    • 0031926417 scopus 로고    scopus 로고
    • Assessing the hypothalamic-pituitary-adrenocortical axis using physiological doses of adrenocorticotropic hormone
    • Talwar V, Lodha S, Dash RJ. Assessing the hypothalamic-pituitary-adrenocortical axis using physiological doses of adrenocorticotropic hormone. QJM 1998;91:285-90.
    • (1998) QJM , vol.91 , pp. 285-290
    • Talwar, V.1    Lodha, S.2    Dash, R.J.3
  • 76
    • 0033304514 scopus 로고    scopus 로고
    • Optimizing the diagnostic criteria for standard (250-μg) and low-dose (1-μg) adrenocorticotropin tests in the assessment of adrenal function
    • Zarkovic M, Ciric J, Stojanovic M, et al. Optimizing the diagnostic criteria for standard (250-μg) and low-dose (1-μg) adrenocorticotropin tests in the assessment of adrenal function. J Clin Endocrinol Metab 1999;84:3170-3.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3170-3173
    • Zarkovic, M.1    Ciric, J.2    Stojanovic, M.3
  • 77
    • 0033623262 scopus 로고    scopus 로고
    • A comparison between the 1-μg adrenocorticotropin (ACTH) test, the short ACTH (250 μg) test, and the insulin tolerance test in the assessment of hypothalamo-pituitary-adrenal axis immediately after pituitary surgery
    • Dökmetas HS, Colak R, Kelestimur F, Selcuklu A, Unluhizarci K, Bayram F. A comparison between the 1-μg adrenocorticotropin (ACTH) test, the short ACTH (250 μg) test, and the insulin tolerance test in the assessment of hypothalamo-pituitary-adrenal axis immediately after pituitary surgery. J Clin Endocrinol Metab 2000;85:3713-19.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3713-3719
    • Dökmetas, H.S.1    Colak, R.2    Kelestimur, F.3    Selcuklu, A.4    Unluhizarci, K.5    Bayram, F.6
  • 78
    • 0036181322 scopus 로고    scopus 로고
    • Cortisol-binding globulin is important in the interpretation of dynamic tests of the hypothalamic-pituitary-adrenal axis
    • Dhillo WS, Kong WM, Le Roux CW, et al. Cortisol-binding globulin is important in the interpretation of dynamic tests of the hypothalamic-pituitary-adrenal axis. Eur J Endocrinol 2001;146:231-5.
    • (2001) Eur J Endocrinol , vol.146 , pp. 231-235
    • Dhillo, W.S.1    Kong, W.M.2    Le Roux, C.W.3
  • 79
    • 0033561805 scopus 로고    scopus 로고
    • Relative eosinophilia and functional adrenal insufficiency in critically ill patients
    • Beishuizen A, Vermes I, Hylkema BS, Haanen C. Relative eosinophilia and functional adrenal insufficiency in critically ill patients. Lancet 1999;353:1675-6.
    • (1999) Lancet , vol.353 , pp. 1675-1676
    • Beishuizen, A.1    Vermes, I.2    Hylkema, B.S.3    Haanen, C.4
  • 80
    • 0027131202 scopus 로고
    • Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans
    • Mastorakos G, Chrousos GP, Weber JS. Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans. J Clin Endocrinol Metab 1993;77:1690-4.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1690-1694
    • Mastorakos, G.1    Chrousos, G.P.2    Weber, J.S.3
  • 81
    • 0025878555 scopus 로고
    • Interleukin-1 and interleukin-6 act synergistically to stimulate the release of adrenocorticotropic hormone in vivo
    • Perlstein RS, Mougey EH, Jackson WE, Neta R. Interleukin-1 and interleukin-6 act synergistically to stimulate the release of adrenocorticotropic hormone in vivo. Lymphokine Cytokine Res 1991;10:141-6.
    • (1991) Lymphokine Cytokine Res , vol.10 , pp. 141-146
    • Perlstein, R.S.1    Mougey, E.H.2    Jackson, W.E.3    Neta, R.4
  • 82
    • 0027511919 scopus 로고
    • Synergistic roles of interleukin-6, interleukin-1, and tumor necrosis factor in adrenocorticotropin response to bacterial lipopolysaccharide in vivo
    • Perlstein RS, Whitnall MH, Abrams JS, Mougey EH, Neta R. Synergistic roles of interleukin-6, interleukin-1, and tumor necrosis factor in adrenocorticotropin response to bacterial lipopolysaccharide in vivo. Endocrinology 1993;132:946-52.
    • (1993) Endocrinology , vol.132 , pp. 946-952
    • Perlstein, R.S.1    Whitnall, M.H.2    Abrams, J.S.3    Mougey, E.H.4    Neta, R.5
  • 83
    • 0026442110 scopus 로고
    • A central mechanism is involved in the secretion of ACTH in response to IL-6 in rats: Comparison to and interaction with IL-1b
    • Matta SG, Weatherbee J, Sharp BM. A central mechanism is involved in the secretion of ACTH in response to IL-6 in rats: comparison to and interaction with IL-1b. Neuroendocrinology 1992;56:516-25.
    • (1992) Neuroendocrinology , vol.56 , pp. 516-525
    • Matta, S.G.1    Weatherbee, J.2    Sharp, B.M.3
  • 84
    • 0025743630 scopus 로고
    • The effect of interleukin-6 on pituitary hormone release in vivo and in vitro
    • Lyson K, McCann SM. The effect of interleukin-6 on pituitary hormone release in vivo and in vitro. Neuroendocrinology 1991;54:262-6.
    • (1991) Neuroendocrinology , vol.54 , pp. 262-266
    • Lyson, K.1    McCann, S.M.2
  • 85
    • 0030839840 scopus 로고    scopus 로고
    • Interleukin-6 and the interleukin-6 receptor in the human adrenal gland: Expression and effects on steroidogenesis
    • Path G, Bornstein SR, Ehrhart-Bornstein M, Scherbaum WA. Interleukin-6 and the interleukin-6 receptor in the human adrenal gland: expression and effects on steroidogenesis. Clin Endocrinol Metab 1997;82:2343-9.
    • (1997) Clin Endocrinol Metab , vol.82 , pp. 2343-2349
    • Path, G.1    Bornstein, S.R.2    Ehrhart-Bornstein, M.3    Scherbaum, W.A.4
  • 86
    • 0027168792 scopus 로고
    • The hypothalamic-pituitary-adrenal axis in critical illness: Response to dexamethasone and corticotropin-releasing hormone
    • Reincke M, Allolio B, Wurth G, Winkelmann W. The hypothalamic-pituitary-adrenal axis in critical illness: response to dexamethasone and corticotropin-releasing hormone. J Clin Endocrinol Metab 1993;77:151-6.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 151-156
    • Reincke, M.1    Allolio, B.2    Wurth, G.3    Winkelmann, W.4
  • 87
    • 0035072786 scopus 로고    scopus 로고
    • Adrenocortical response and cortisone replacement in systemic inflammatory response syndrome
    • Ihle BU. Adrenocortical response and cortisone replacement in systemic inflammatory response syndrome. Anaesth Intensive Care 2001;29:155-62.
    • (2001) Anaesth Intensive Care , vol.29 , pp. 155-162
    • Ihle, B.U.1
  • 88
    • 0035100186 scopus 로고    scopus 로고
    • Sepsis-induced adrenal deficiency syndrome
    • Zaloga GP. Sepsis-induced adrenal deficiency syndrome. Crit Care Med 2001;29:688-90.
    • (2001) Crit Care Med , vol.29 , pp. 688-690
    • Zaloga, G.P.1
  • 89
    • 0026081771 scopus 로고
    • Tumor necrosis factor as a potent inhibitor of adrenocorticotropin-induced cortisol production and steroidogenic P450 enzyme gene expression in cultured human fetal adrenal cells
    • Jaattela M, Ilvesmaki V, Voutilainen R, Stenman UH, Saksela E. Tumor necrosis factor as a potent inhibitor of adrenocorticotropin-induced cortisol production and steroidogenic P450 enzyme gene expression in cultured human fetal adrenal cells. Endocrinology 1991;128:623-9.
    • (1991) Endocrinology , vol.128 , pp. 623-629
    • Jaattela, M.1    Ilvesmaki, V.2    Voutilainen, R.3    Stenman, U.H.4    Saksela, E.5
  • 90
    • 0025288875 scopus 로고
    • Tumor necrosis factor alpha inhibits response of the pituitary gland to hypothalamic releasing factors
    • Gaillard RC, Turnhill D, Sappino P, Muller AF. Tumor necrosis factor alpha inhibits response of the pituitary gland to hypothalamic releasing factors. Endocrinology 1990;127:101-6.
    • (1990) Endocrinology , vol.127 , pp. 101-106
    • Gaillard, R.C.1    Turnhill, D.2    Sappino, P.3    Muller, A.F.4
  • 91
    • 0026603465 scopus 로고
    • Isolation and mode of action of rabbit corticostatic (antiadrenocorticotropin) peptides
    • Zhu Q, Solomon S. Isolation and mode of action of rabbit corticostatic (antiadrenocorticotropin) peptides. Endocrinology 1992;130:1413-23.
    • (1992) Endocrinology , vol.130 , pp. 1413-1423
    • Zhu, Q.1    Solomon, S.2
  • 92
    • 0026504966 scopus 로고
    • Distribution and characterization of immunoreactive corticostatin in the hypothalamic-pituitary-adrenal axis
    • Tominaga T, Fukata J, Hayashi Y, et al. Distribution and characterization of immunoreactive corticostatin in the hypothalamic-pituitary-adrenal axis. Endocrinology 1992;130:1593-8.
    • (1992) Endocrinology , vol.130 , pp. 1593-1598
    • Tominaga, T.1    Fukata, J.2    Hayashi, Y.3
  • 94
    • 0019796951 scopus 로고
    • Effects of septic shock plasma on adrenocortical cell function
    • Keri G, Parameswaran V, Trunkey DD, Ramachandran J. Effects of septic shock plasma on adrenocortical cell function. Life Sci 1981;28:1917-23.
    • (1981) Life Sci , vol.28 , pp. 1917-1923
    • Keri, G.1    Parameswaran, V.2    Trunkey, D.D.3    Ramachandran, J.4
  • 95
    • 0029166231 scopus 로고
    • Temperature-induced down-regulation of the glucocorticoid receptor in peripheral blood mononuclear leucocyte in patients with sepsis and septic shock
    • Molijn GJ, Koper JW, van Uffelen JC, et al. Temperature-induced down-regulation of the glucocorticoid receptor in peripheral blood mononuclear leucocyte in patients with sepsis and septic shock. Clin Endocrinol 1995;43:197-203.
    • (1995) Clin Endocrinol , vol.43 , pp. 197-203
    • Molijn, G.J.1    Koper, J.W.2    Van Uffelen, J.C.3
  • 96
    • 0027242280 scopus 로고
    • Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids
    • Kam JC, Szefler SJ, Surs W, et al. Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids. J Immunol 1993;151:3460-6.
    • (1993) J Immunol , vol.151 , pp. 3460-3466
    • Kam, J.C.1    Szefler, S.J.2    Surs, W.3
  • 97
    • 0025922666 scopus 로고
    • Abrogation of glucocorticoid-mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6, and IFN-gamma
    • Almawi WY, Lipman ML, Stevens AC, Zanker B, Hadro ET, Strom TB. Abrogation of glucocorticoid-mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6, and IFN-gamma. J Immunol 1991;146:3523-7.
    • (1991) J Immunol , vol.146 , pp. 3523-3527
    • Almawi, W.Y.1    Lipman, M.L.2    Stevens, A.C.3    Zanker, B.4    Hadro, E.T.5    Strom, T.B.6
  • 98
    • 0034926040 scopus 로고    scopus 로고
    • Corticosteroids for septic shock
    • Annane D. Corticosteroids for septic shock. Crit Care Med 2001;29:S117-20.
    • (2001) Crit Care Med , vol.29
    • Annane, D.1
  • 99
    • 0034965716 scopus 로고    scopus 로고
    • Glucocorticoid and mineralocorticoid resistance/hypersensitivity syndromes
    • Kino T, Chrousos GP. Glucocorticoid and mineralocorticoid resistance/hypersensitivity syndromes. J Endocrinol 2001;169:437-45.
    • (2001) J Endocrinol , vol.169 , pp. 437-445
    • Kino, T.1    Chrousos, G.P.2
  • 101
    • 0029051393 scopus 로고
    • Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leukocytes in patients with sepsis or septic shock
    • Molijn GJ, Spek JJ, van Uffelen JCJ, deJong FH, Brinkmann AO, Bruining HA. Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leukocytes in patients with sepsis or septic shock. J Clin Endocrinol Metab 1995;80:1799-803.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1799-1803
    • Molijn, G.J.1    Spek, J.J.2    Van Uffelen, J.C.J.3    DeJong, F.H.4    Brinkmann, A.O.5    Bruining, H.A.6
  • 102
    • 0034284349 scopus 로고    scopus 로고
    • Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: Negative interference of activated glucocorticoid receptor with transcription factors
    • De Bosscher K, Berghe WV, Haegerman G. Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors. J Neuroimmunol 2000;109:16-22.
    • (2000) J Neuroimmunol , vol.109 , pp. 16-22
    • De Bosscher, K.1    Berghe, W.V.2    Haegerman, G.3
  • 103
    • 0029737089 scopus 로고    scopus 로고
    • Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids
    • Didonato JA, Saatcioglu F, Karin M. Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids. Am J Respir Crit Care Med 1996;154:S11-15.
    • (1996) Am J Respir Crit Care Med , vol.154
    • Didonato, J.A.1    Saatcioglu, F.2    Karin, M.3
  • 104
    • 0034113383 scopus 로고    scopus 로고
    • Increased nuclear factor κB activation in critically ill patients who die
    • Paterson RL, Galley HF, Dhillon JK, Webster NR. Increased nuclear factor κB activation in critically ill patients who die. Crit Care Med 2000;28:1047-51.
    • (2000) Crit Care Med , vol.28 , pp. 1047-1051
    • Paterson, R.L.1    Galley, H.F.2    Dhillon, J.K.3    Webster, N.R.4
  • 105
    • 0030611086 scopus 로고    scopus 로고
    • Role of NFkappaB in the mortality of sepsis
    • Bohrer H, Qiu F, Zimmermann T, et al. Role of NFkappaB in the mortality of sepsis. J Clin Invest 1997;100:972-85.
    • (1997) J Clin Invest , vol.100 , pp. 972-985
    • Bohrer, H.1    Qiu, F.2    Zimmermann, T.3
  • 107
    • 0034018465 scopus 로고    scopus 로고
    • NF-κB activation
    • Abraham E. NF-κB activation. Crit Care Med 2000;28:N100-4.
    • (2000) Crit Care Med , vol.28
    • Abraham, E.1
  • 108
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of Ikappa B synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of Ikappa B synthesis. Science 1995;270:286-90.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 109
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin ASJ. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 1995;270:283-6.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.J.4
  • 110
    • 0031416497 scopus 로고    scopus 로고
    • Dexamethasone suppresses iNOS gene expression by upregulating I-kappa B alpha and inhibiting NF-kappa B
    • De Vera ME, Taylor BS, Wang Q, Shapiro RA, Billiar TR, Geller DA. Dexamethasone suppresses iNOS gene expression by upregulating I-kappa B alpha and inhibiting NF-kappa B. Am J Physiol 1997;273:G1290-6.
    • (1997) Am J Physiol , vol.273
    • De Vera, M.E.1    Taylor, B.S.2    Wang, Q.3    Shapiro, R.A.4    Billiar, T.R.5    Geller, D.A.6
  • 111
    • 0034966944 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor and hypothalamo-pituitary-adrenal function during critical illness
    • Beishuizen A, Thijs LG, Haanen C, Vermes I. Macrophage migration inhibitory factor and hypothalamo-pituitary-adrenal function during critical illness. J Clin Endocrinol Metab 2001;86:2811-16.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2811-2816
    • Beishuizen, A.1    Thijs, L.G.2    Haanen, C.3    Vermes, I.4
  • 112
    • 0036162165 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor
    • Baugh JA, Bucala R. Macrophage migration inhibitory factor. Crit Care Med 2002;30:S27-35.
    • (2002) Crit Care Med , vol.30
    • Baugh, J.A.1    Bucala, R.2
  • 113
    • 0033833595 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic IkappaBalpha
    • Daun JM, Cannon JG. Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic IkappaBalpha. Am J Physiol Regul Integr Comp Physiol 2000;279:R1043-9.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279
    • Daun, J.M.1    Cannon, J.G.2
  • 114
  • 115
    • 0035144237 scopus 로고    scopus 로고
    • Immunomodulation in septic shock: Hydrocortisone differentially regulates cytokine responses
    • Briegel J, Jochum M, Gippner-Steppert C, Thiel M. Immunomodulation in septic shock: hydrocortisone differentially regulates cytokine responses. J Am Soc Nephrol 2001;12:S70-4.
    • (2001) J Am Soc Nephrol , vol.12
    • Briegel, J.1    Jochum, M.2    Gippner-Steppert, C.3    Thiel, M.4
  • 116
    • 0033111565 scopus 로고    scopus 로고
    • Inhibition of VCAM-1 expression in human bronchial epithelial cells by glucocorticoids
    • Atsuta J, Plitt J, Bochner BS, Schleimer RP. Inhibition of VCAM-1 expression in human bronchial epithelial cells by glucocorticoids. Am J Respir Cell Mol Biol 1999;20:643-50.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 643-650
    • Atsuta, J.1    Plitt, J.2    Bochner, B.S.3    Schleimer, R.P.4
  • 117
    • 0026470092 scopus 로고
    • A mechanism for the antiinflammatory effects of corticosteroids: The glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1
    • Cronstein BN, Kimmel SC, Levin RI, Martiniuk F, Weissmann G. A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci 1992;89:9991-5.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 9991-9995
    • Cronstein, B.N.1    Kimmel, S.C.2    Levin, R.I.3    Martiniuk, F.4    Weissmann, G.5
  • 118
    • 0035208279 scopus 로고    scopus 로고
    • The human pharmacology of monocyte cyclooxygenase 2 inhibition by cortisol and synthetic glucocorticoids
    • Santini G, Patrignani P, Sciulli MG, et al. The human pharmacology of monocyte cyclooxygenase 2 inhibition by cortisol and synthetic glucocorticoids. Clin Pharmacol Ther 2001;70:475-83.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 475-483
    • Santini, G.1    Patrignani, P.2    Sciulli, M.G.3
  • 119
    • 0036141917 scopus 로고    scopus 로고
    • Adrenoceptor hyporeactivity is responsible for Escherichia coli endotoxin-induced acute vascular dysfunction in humans
    • Pleiner J, Heere-Ress E, Langenberger H, et al. Adrenoceptor hyporeactivity is responsible for Escherichia coli endotoxin-induced acute vascular dysfunction in humans. Arterioscler Thromb Vasc Biol 2002;22:95-100.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 95-100
    • Pleiner, J.1    Heere-Ress, E.2    Langenberger, H.3
  • 121
    • 0025672648 scopus 로고
    • Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells
    • Radomski MW, Palmer RMJ, Moncada S. Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc Natl Acad Sci 1990;87:10043-7.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 10043-10047
    • Radomski, M.W.1    Palmer, R.M.J.2    Moncada, S.3
  • 122
    • 0033306816 scopus 로고    scopus 로고
    • Differential inhibitory actions by glucocorticoid and aspirin on cytokine-induced nitric oxide production in vascular smooth muscle cells
    • Katsuyama K, Shichiri M, Kato H, Imai T, Marumo F, Hirata Y. Differential inhibitory actions by glucocorticoid and aspirin on cytokine-induced nitric oxide production in vascular smooth muscle cells. Endocrinology 1999;140:2183-90.
    • (1999) Endocrinology , vol.140 , pp. 2183-2190
    • Katsuyama, K.1    Shichiri, M.2    Kato, H.3    Imai, T.4    Marumo, F.5    Hirata, Y.6
  • 123
    • 0035919647 scopus 로고    scopus 로고
    • Dexamethasone suppresses iNOS gene expression by inhibiting NF-kappaB in vascular smooth muscle cells
    • Matsumura M, Kakishita H, Suzuki M, Banba N, Hattori Y. Dexamethasone suppresses iNOS gene expression by inhibiting NF-kappaB in vascular smooth muscle cells. Life Sci 2001;69:1067-77.
    • (2001) Life Sci , vol.69 , pp. 1067-1077
    • Matsumura, M.1    Kakishita, H.2    Suzuki, M.3    Banba, N.4    Hattori, Y.5
  • 124
    • 0032713897 scopus 로고    scopus 로고
    • Hydrocortisone-induced inhibition of reactive oxygen species by polymorphonuclear neutrophils
    • Dandona P, Suri M, Hamouda W, Aljada A, Kumbkarni Y, Thusu K. Hydrocortisone-induced inhibition of reactive oxygen species by polymorphonuclear neutrophils. Crit Care Med 1999;27:2442-4.
    • (1999) Crit Care Med , vol.27 , pp. 2442-2444
    • Dandona, P.1    Suri, M.2    Hamouda, W.3    Aljada, A.4    Kumbkarni, Y.5    Thusu, K.6
  • 125
    • 0020675221 scopus 로고
    • Peripheral vascular adrenergic depression during hypotension induced by E. coli endotoxin
    • Bond RF. Peripheral vascular adrenergic depression during hypotension induced by E. coli endotoxin. Adv Shock Res 1983;9:157-69.
    • (1983) Adv Shock Res , vol.9 , pp. 157-169
    • Bond, R.F.1
  • 126
    • 0035940129 scopus 로고    scopus 로고
    • Mechanisms of disease: The pathogenesis of vasodilatory shock
    • Landry DW, Oliver JA. Mechanisms of disease: the pathogenesis of vasodilatory shock. N Engl J Med 2001;345:588-95.
    • (2001) N Engl J Med , vol.345 , pp. 588-595
    • Landry, D.W.1    Oliver, J.A.2
  • 127
    • 0036185788 scopus 로고    scopus 로고
    • Depletion of neurohypophyseal content of vasopressin in septic shock
    • Sharshar T, Carlier R, Blanchard A, et al. Depletion of neurohypophyseal content of vasopressin in septic shock. Crit Care Med 2002;30:497-500.
    • (2002) Crit Care Med , vol.30 , pp. 497-500
    • Sharshar, T.1    Carlier, R.2    Blanchard, A.3
  • 129
    • 0035025450 scopus 로고    scopus 로고
    • Effect of corticosteroids on nuclear factor-kappa-B activation and hemodynamics in late septic shock
    • van Leeuwen HJ, van der Bruggen T, van Asbeck BS, Boereboom FT. Effect of corticosteroids on nuclear factor-kappa-B activation and hemodynamics in late septic shock. Crit Care Med 2001;29:1074-7.
    • (2001) Crit Care Med , vol.29 , pp. 1074-1077
    • Van Leeuwen, H.J.1    Van der Bruggen, T.2    Van Asbeck, B.S.3    Boereboom, F.T.4
  • 130
    • 0033829922 scopus 로고    scopus 로고
    • Effect of hydrocortisone on phenylephrine-mean arterial pressure dose-response relationship in septic shock
    • Bellissant E, Annane D. Effect of hydrocortisone on phenylephrine-mean arterial pressure dose-response relationship in septic shock. Clin Pharmacol Ther 2000;68:293-303.
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 293-303
    • Bellissant, E.1    Annane, D.2
  • 131
    • 0031722907 scopus 로고    scopus 로고
    • Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve
    • Annane D, Bellissant E, Sebille V, et al. Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve. Br J Clin Pharmacol 1998;46:589-97.
    • (1998) Br J Clin Pharmacol , vol.46 , pp. 589-597
    • Annane, D.1    Bellissant, E.2    Sebille, V.3
  • 132
    • 0025718605 scopus 로고
    • Abrupt hemodynamic improvement in late septic shock with physiological doses of glucocorticoid
    • Schneider AJ, Voerman HJ. Abrupt hemodynamic improvement in late septic shock with physiological doses of glucocorticoid. Intensive Care Med 1991;17:436-7.
    • (1991) Intensive Care Med , vol.17 , pp. 436-437
    • Schneider, A.J.1    Voerman, H.J.2
  • 133
    • 0020616711 scopus 로고
    • Effectiveness of modified steroid-antibiotic therapies for lethal sepsis in the dog
    • Beller BK, Archer LT, Passey RB, Flournoy DJ, Hinshaw LB. Effectiveness of modified steroid-antibiotic therapies for lethal sepsis in the dog. Arch Surg 1983;118:1293-9.
    • (1983) Arch Surg , vol.118 , pp. 1293-1299
    • Beller, B.K.1    Archer, L.T.2    Passey, R.B.3    Flournoy, D.J.4    Hinshaw, L.B.5
  • 135
    • 0021184906 scopus 로고
    • The effects of high-dose corticosteroids in patients with septic shock: A prospective, controlled study
    • Sprung CL, Caralis PV, Marcial EH, Pierce M, Gelbard MA, Long WM. The effects of high-dose corticosteroids in patients with septic shock: a prospective, controlled study. N Engl J Med 1984;311:1137-43.
    • (1984) N Engl J Med , vol.311 , pp. 1137-1143
    • Sprung, C.L.1    Caralis, P.V.2    Marcial, E.H.3    Pierce, M.4    Gelbard, M.A.5    Long, W.M.6
  • 136
    • 0021359315 scopus 로고
    • The cardiopulmonary response to massive doses of steroids in patients with septic shock
    • Lucas CE, Ledgerwood AM. The cardiopulmonary response to massive doses of steroids in patients with septic shock. Arch Surg 1984;119:537-41.
    • (1984) Arch Surg , vol.119 , pp. 537-541
    • Lucas, C.E.1    Ledgerwood, A.M.2


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