Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve

British Journal of Clinical Pharmacology

Volumn 46, Issue 6, 1998, Pages 589-597

  Annane, D ^a   Bellissant, E ^b   Sebille, V ^b   Lesieur, O ^a   Mathieu, B ^a   Raphael, J C ^a   Gajdos, P ^a  

^a RAYMOND POINCARÉ HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Adrenal function; Dose response curve; Hydrocortisone; Noradrenaline; Septic shock

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE; NORADRENALIN;

ADRENAL DISEASE; ADRENAL FUNCTION; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MEAN ARTERIAL PRESSURE; PRESSOR RESPONSE; PRIORITY JOURNAL; SEPTIC SHOCK;

ADRENAL GLAND DISEASES; ADRENAL GLANDS; ADULT; AGED; BAROREFLEX; BLOOD PRESSURE; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; NOREPINEPHRINE; SHOCK, SEPTIC; VASOCONSTRICTOR AGENTS;

EID: 0031722907     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1998.00833.x     Document Type: Article

References (44)

1. Parillo JE. Cardiovascular pattern during septic shock. Ann Intern Med 1990; 113: 227-228.
2. Parrillo JE. Pathogenic mechanisms of septic shock. N Engl J Med 1993; 328: 1471-1477.
3. Glauser MP, Zanetti G, Baumgartner JD, Cohen J. Septic shock: pathogenesis. Lancet 1991; 338: 732-735.
4. Parker MM. Cardiac dysfunction in human septic shock. Ann Intern Med 1990; 113: 229-230.
5. Bond RF. Peripheral vascular adrenergic depression during hypotension induced by E. coli endotoxin. Adv Shock Res 1983; 9: 157-169.
6. Abel FL, Beck RR. Canine peripheral vascular response to endotoxin shock at a constant cardiac output. Circ Shock 1988; 25: 267-274.
7. Joulou-Schaeffer G, Gray GA, Fleming I, Schott C, Parrat JR, Stoclet JC. Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. Am J Physiol 1990; 259: H1038-H1043.
8. Beasley D, Cohen RA, Levinsky NA. Endotoxin inhibits contraction of vascular smooth muscle in vitro. Am J Physiol 1990; 258: H1187-H1192.
9. Moncada S. The L-arginine/nitric oxide pathway. Acta Physiol Scand 1992; 145: 201-227.
10. Bond RF, Scott CG, Clevenger JC, Bond CH, Abel FL. Effect of systemic endotoxin on muscle vascular conductance during high and low adrenergic tone. Circ Shock 1990; 30: 311-322.
11. Romano FD, Jones SB. Beta adrenergic stimulation of myocardial cyclic AMP in endotoxic rats. Circ Shock 1985; 17: 243-252.
12. Motulsky HJ, Insel PA. Adrenergic receptors in man. Direct identification, physiologic regulation, and clinical alterations. N Engl J Med 1982; 307: 18-29.
13. Sibbald WJ, Short A, Chohen MP, Wilson RF. Variations in adrenocortical responsiveness during severe bacterial infections. Ann Surg 1977; 186: 29-33.
14. Davies AO, Lefkowitz RJ. Regulation of adrenergic receptor. In Receptor regulation, eds. Lefkowitz RJ, New York: Chapman & Hall: 1981: 85-121.
15. Rothwell PM, Udwadia ZF, Lawler PG. Cortisol response to corticotropin and survival in septic shock. Lancet 1991; 337: 582-583.
16. Annane D, Bellissant E, Bollaert PE, et al. The hypothalamo-pituitary axis in septic shock. Br J Intens Care 1996; 6: 260-268.
17. Hinshaw LB, Beller BK, Chang ACK, et al. Corticosteroid/ antibiotic treatment of adrenalectomized dogs challenged with lethal E. coli. Circ Shock 1985; 16: 265-277.
18. McKee JI, Finlay WE. Cortisol replacement in severely stressed patients. Lancet 1983; i: 484.
19. Benfield K, Cooper J, Scheinkestel CD, Tuxen DV. Relative-adrenal insufficiency in patients with septic shock. Anaesth Intens Care 1994; 22: 215-216.
20. Bollaert PE, Charpentier C, Lévy B, et al. Reversal of late septic shock with supraphysiologic doses of hydrocortisone. Crit Care Med 1998; 26: 645-650.
21. Bone RC. Sepsis, the sepsis syndrome, multi-organ failure: a plea for comparable definitions. Ann Intern Med 1991; 114: 332-333.
22. Le Gall JR, Lemeshow S, Saulnier F. A new simplified acute physiology score (SAPS 11) based on a european/north american multicenter study. J Am Med Ass 1993; 270: 2957-2963.
23. Imholz BPM, Settels JJ, Van den Meiracker AH, Wesseling KH, Wieling W. Noninvasive beat-to-beat finger blood pressure measurement during orthostatic stress compared to intra-arterial pressure. Cardiovasc Res 1990; 24: 214-221.
24. Elghozi JL, Laude D, Janvier F. Clonidine reduces blood pressure and heart rate oscillations in hypertensive patients. J Cardiovasc Pharmacol 1991; 17: 935-940.
25. Parati G, Gasadei R, Gropelli A, Di Rienzo A, Mancia G. Comparison of finger and intraarterial blood pressure monitoring in rest and during laboratory tests. Hypertension 1989; 13: 647-655.
26. Wieling W. Non-invasive continuous recording of heart rate and blood pressure in the evaluation of neurocardiovascular control. In Autonomic failure: a text book of clinical disorders of the autonomic nervous system, eds Bannister R, Mathias CJ, Oxford: Oxford University Press; 1992: 291-311.
27. Ménard J, Corvol P, Allegrini J, Breminer J. Méthode de mesure de l'activité rénine plasmatique de l'homme par dosage radioimmunologique de l'angiotensine I. In INSERM, eds. Techniques de radioimmunologie. Paris, France: INSERM 1972: 459-469.
28. Pham-Huu-Trung MT, Corvol P. A direct determination of plasma aldosterone. Steroids 1974; 24: 587-598.
29. ++ dependent constitutive nitric oxide synthase is not involved in the cyclic GMP-increasing effects of carbachol in ventricular cardiomyocytes. J Pharmacol Exp Ther 1993; 266: 919-925.
30. Causon RC, Carruthers ME, Rodnight R. Assay of plasma catecholamines by liquid chromatography with electrochemical detection. Anal Biochem 1981; 116: 223-226.
31. Lamberts SWJ, Bruining HA, De Jong FH. Corticosteroid therapy in severe illness. N Engl J Med 1997; 337: 1285-1292.
32. Oelkers W. Adrenal insufficiency. N Engl J Med 1996; 335: 1206-1212.
33. Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 1995; 332: 1351-1362.
34. Soni A, Pepper GM, Wyrinski PM, et al. Adrenal insufficiency occuring during septic shock: incidence, outcome, and relationship to peripheral cytokine levels. Am J Med 1995; 98: 266-271.
35. Innes IR, Nickerson M. Norepinephrine, epinephrine, and the sympathomimetic amines. In The pharmacological basis of therapeutics. eds, Goodman LS, Gilman A, Gilman AG, Koelle GB, New York: Macmillan Publishing Co; 1975: 477-513.
36. Karzai W, Reilly JM, Hoffman WD, et al. Hemodynamic effects of dopamine, norepinephrine, and fluids in a dog model of sepsis. Am J Physiol 1995; 268 (Heart Circ Physiol 37): H692-H702.
37. Parrat JR. Myocardial and circulatory effects of E. coli endotoxin: modification of response to catecholamines. Br J Pharmacol 1973; 47: 12-25.
38. Breslow M, Miller CF, Parker SD, Walman AT. Traystman RJ. Effects of vasopressors on organ blood flow during endotoxin shock in pigs. Am J Physiol 1987; 252 (Heart Circ Physiol 21): H291-H300.
39. Bernstein AD, Hersch M, Cheung FS, Rutledge FS, Sibbald WJ. The effects of various sympathomimetics on the regional circulation in hyperdynamic sepsis. Surgery 1992; 112: 549-561.
40. Hoffman WD, Banks SM, Alling DW, et al. Factors that determine the hemodynamic response to inhalation anesthetics. J Appl Physiol 1991; 70: 2155-2163.
41. Sprung CL, Caralis PV, Marcial EH, et al. The effects of high dose corticosteroids in patients with septic shock. A prospective, controlled study. N Engl J Med 1984; 311: 1137-1143.
42. Chrousos GP, Lave L, Nieman LK. Glucocorticoids and glucocorticoids antagonist: lessons from RU 486. Kidney Int 1988; 34: S18-S23.
43. Grünfeld JP, Eloy L. Glucocorticoid antagonists as probes to study the vascular effects of glucocorticoids. Kidney Int 1988; 34: S24-S26.
44. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-2012.