Corticosteroids for septic shock

Critical Care Medicine

Volumn 29, Issue 7 SUPPL., 2001, Pages

  Annane, D ^a  

^a RAYMOND POINCARÉ HOSPITAL   (France)

Author keywords

Adrenal insufficiency; Catecholamine; Clinical controlled trials; Corticosteroids; Experimental studies; Septic shock

Indexed keywords

CATECHOLAMINE; CORTICOSTEROID; HYDROCORTISONE;

CLINICAL TRIAL; CONFERENCE PAPER; DISEASE SEVERITY; DRUG MECHANISM; DRUG SAFETY; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; SUBSTITUTION THERAPY; SURVIVAL; TREATMENT OUTCOME;

EID: 0034926040     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200107001-00036     Document Type: Conference Paper

References (52)

1. Suprarenal cortical hormone and salt in the treatment of pneumonia and other severe infections
2. Steroid controversy in sepsis and septic shock: A meta-analysis
3. Corticosteroid treatment for sepsis: A critical appraisal and meta-analysis of the literature
4. The hypothalamic-pituitary adrenal axis and immune mediated inflammation
5. Individual variation in hypothalamic-pituitary adrenal responsiveness of rats to endotoxin and interleukin-1β
6. Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism
7. Subdiaphragmatic vagotomy suppresses endotoxin-induced activation of hypothalamic corticotropin-releasing hormone neurons and ACTH secretion
8. Case of suprarenal apoplexy
9. Nebennierenapoplexie bei kleinen Kindern
10. The hypothalamo-pituitary axis in septic shock
11. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin
12. Impaired pressor sensitivity to norepinephrine in septic shock patients with and without impaired adrenal function reserve
13. Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leukocytes in patients with sepsis or septic shock
14. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
15. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
16. Temperature-induced down-regulation of the glucocorticoid receptor in peripheral blood mononuclear leucocyte in patients with sepsis or septic shock
17. Molecular mechanisms of action of steroid/thyroid receptor superfamily members
18. Biological and clinical aspects of interleukin 6
19. Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer
20. Transcription factor interactions: Selectors of positive or negative regulation from a single DNA element
21. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor
22. Novel mechanism of glucocorticoid-mediated gene repression: Nuclear factor-κB is target for glucocorticoid-mediated interleukin 8 gene repression
23. Dexamethasone inhibits the induction of monocyte chemostatic-activating factor production by IL-1 or tumor necrosis factor
24. MIF as a glucocorticoid-induced modulator of cytokine production
25. Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1
26. Corticosteroids suppress cyclooxygenase messenger RNA levels and prostanoid synthesis in cultured vascular cells
27. Effects of topical corticosteroids on inflammatory mediator-induced eicosanoid release by human airway epithelial cells
28. Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages
29. Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells
30. Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man
31. Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to ehdotoxin in human beings
32. Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia: A clinical research center study
33. Low dose hydrocortisone attenuates the systemic inflammatory response syndrome
34. Effects of hydrocortisone on the immune response in patients with septic shock: Results from a double-blind cross-over study
35. Glucocorticoids modulate vascular reactivity in the rat
36. Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo
37. Studies of the mechanisms of hydrocortisone potentiation of vasoconstrictor responses to epinephrine in the anesthetized animal
38. Cortisol and hypertension
39. Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo
40. Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats
41. Local venous responses to endotoxin in humans
42. Effect of hydrocortisone on phenylephrine-mean arterial pressure dose-response relationship in septic shock
43. The cardiopulmonary response to massive doses of steroids in patients with septic shock
44. The effects of high-dose corticosteroids in patients with septic shock: A prospective, controlled study
45. Reversal of late septic shock with supraphysiologic doses of hydrocortisone
46. Stress doses of hydrocortisone reverse hyperdynamic septic shock: A prospective, randomized, double-blind, single-center study
47. Hydrocortisone reverses refractory septic shock
48. The effectiveness of hydrocortisone in the management of severe infections
49. Cortisol replacement in severely stressed patients
50. Reduction of mortality in chloramphenicol-treated severe typhoid fever by high-dose dexamethasone
51. Corticosteroids as adjunctive therapy for severe pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome: A double-blind, placebo-controlled trial
52. The beneficial effects of early dexamethasone administration in infants and children with bacterial meningitis