메뉴 건너뛰기




Volumn 8, Issue 1, 2003, Pages 71-83

Cardiovascular pharmacogenomics: Current status, future prospects

Author keywords

Pharmacogenetics; Pharmacogenomics

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ADDUCIN; ALPHA 2 ADRENERGIC RECEPTOR; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSINOGEN; ANTIARRHYTHMIC AGENT; ANTICOAGULANT AGENT; ANTILIPEMIC AGENT; APOLIPOPROTEIN E; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRADYKININ; CARDIOVASCULAR AGENT; CARRIER PROTEIN; CYTOCHROME P450; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; FIBRINOGEN; GUANINE NUCLEOTIDE BINDING PROTEIN; HEPARIN; LIPOPROTEIN LIPASE; LIVER TRIACYLGLYCEROL LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR; ORAL CONTRACEPTIVE AGENT; PROTHROMBIN; STROMELYSIN; UNINDEXED DRUG;

EID: 0037346529     PISSN: 10742484     EISSN: None     Source Type: Journal    
DOI: 10.1177/107424840300800i110     Document Type: Review
Times cited : (34)

References (68)
  • 1
    • 0035553086 scopus 로고    scopus 로고
    • Drug Target Pharmacogenomics: An overview
    • Johnson JA. Drug Target Pharmacogenomics: An overview. Am J Pharmacogenomics 1:271-281, 2001
    • (2001) Am J Pharmacogenomics , vol.1 , pp. 271-281
    • Johnson, J.A.1
  • 3
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. Pharmacogenomics: Translating functional genomics into rational therapeutics. Science 286:487-491, 1999
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 4
    • 0034660560 scopus 로고    scopus 로고
    • Pharmacogenetics and the practice of medicine
    • Roses AD. Pharmacogenetics and the practice of medicine. Nature 405:857-865, 2000
    • (2000) Nature , vol.405 , pp. 857-865
    • Roses, A.D.1
  • 6
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome, Science 291:1304-1351, 2001
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 7
    • 0035865087 scopus 로고    scopus 로고
    • A physical map of the human genome
    • The International Human Genome Mapping Consortium. A physical map of the human genome. Nature 409:934-941, 2001
    • (2001) Nature , vol.409 , pp. 934-941
  • 8
    • 0035861004 scopus 로고    scopus 로고
    • Implications of the human genome for understanding human biology and medicine
    • Subramanian G, Adams MD, Venter JC, Broder S. Implications of the human genome for understanding human biology and medicine. JAMA 286:2296-2307, 2001
    • (2001) JAMA , vol.286 , pp. 2296-2307
    • Subramanian, G.1    Adams, M.D.2    Venter, J.C.3    Broder, S.4
  • 9
    • 0037012486 scopus 로고    scopus 로고
    • Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension
    • Psaty BM, Smith NL, Heckbert SR, et al. Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension. JAMA 287:1680-1689, 2002
    • (2002) JAMA , vol.287 , pp. 1680-1689
    • Psaty, B.M.1    Smith, N.L.2    Heckbert, S.R.3
  • 10
    • 0032908945 scopus 로고    scopus 로고
    • The inherited long QT syndromes: From ion channel to bedside
    • Vincent GM, Timothy K, Fox J, Zhang L. The inherited long QT syndromes: From ion channel to bedside. Cardiol Rev 7:44-55, 1999
    • (1999) Cardiol Rev , vol.7 , pp. 44-55
    • Vincent, G.M.1    Timothy, K.2    Fox, J.3    Zhang, L.4
  • 11
    • 0035040834 scopus 로고    scopus 로고
    • Pharmacogenetics and drug-induced arrhythmias
    • Roden DM. Pharmacogenetics and drug-induced arrhythmias. Cardiovasc Res 50:224-231, 2001
    • (2001) Cardiovasc Res , vol.50 , pp. 224-231
    • Roden, D.M.1
  • 12
    • 0033574273 scopus 로고    scopus 로고
    • MiRP 1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
    • Abbott GW, Sesti F, Splawski I, et al. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. Cell 97:175-187, 1999
    • (1999) Cell , vol.97 , pp. 175-187
    • Abbott, G.W.1    Sesti, F.2    Splawski, I.3
  • 13
    • 0003425462 scopus 로고    scopus 로고
    • A common polymorphism associated with antibiotic-induced cardiac arrhythmia
    • Sesti F, Abbott GW, Wei J, et al. A common polymorphism associated with antibiotic-induced cardiac arrhythmia. Proc Natl Acad Sci USA 97:10613-10618, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10613-10618
    • Sesti, F.1    Abbott, G.W.2    Wei, J.3
  • 14
    • 0034083759 scopus 로고    scopus 로고
    • Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias
    • Napolitano C, Schwartz PJ, Brown AM, et al. Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias, J Cardiovasc Electrophysiol 11:691-696, 2000
    • (2000) J Cardiovasc Electrophysiol , vol.11 , pp. 691-696
    • Napolitano, C.1    Schwartz, P.J.2    Brown, A.M.3
  • 15
    • 18544383162 scopus 로고    scopus 로고
    • Variant of SCN 5A sodium channel implicated in risk of cardiac arrhythmia
    • Splawski I, Timothy KW, Tateyama M, et al. Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia. Science 297:1333-1336, 2002
    • (2002) Science , vol.297 , pp. 1333-1336
    • Splawski, I.1    Timothy, K.W.2    Tateyama, M.3
  • 16
    • 0037015231 scopus 로고    scopus 로고
    • Drug-induced long-QT syndrome associated with a subclinical SCN 5A mutation
    • Makita N, Horie M, Nakamura T, et al. Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation. Circulation 106:1269-1274, 2002
    • (2002) Circulation , vol.106 , pp. 1269-1274
    • Makita, N.1    Horie, M.2    Nakamura, T.3
  • 17
    • 0026651907 scopus 로고
    • Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels
    • Tiret L, Rigat B, Visvikis S, et al. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet 51:197-205, 1992
    • (1992) Am J Hum Genet , vol.51 , pp. 197-205
    • Tiret, L.1    Rigat, B.2    Visvikis, S.3
  • 18
    • 0034606897 scopus 로고    scopus 로고
    • Large-scale test of hypothesised association between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls
    • Keavney B, McKenzie C, Parish S, et al. Large-scale test of hypothesised association between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. Lancet 355:434-442, 2000
    • (2000) Lancet , vol.355 , pp. 434-442
    • Keavney, B.1    McKenzie, C.2    Parish, S.3
  • 19
    • 0029901973 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme genotypes and angiotensin II receptors. Response to therapy
    • Dieguez-Lucena JL, Aranda-Lara P, Ruiz-Galdon M, et al. Angiotensin I-converting enzyme genotypes and angiotensin II receptors. Response to therapy. Hypertension 28:98-103, 1996
    • (1996) Hypertension , vol.28 , pp. 98-103
    • Dieguez-Lucena, J.L.1    Aranda-Lara, P.2    Ruiz-Galdon, M.3
  • 20
    • 0035799777 scopus 로고    scopus 로고
    • Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction
    • Exner DV, Dries DL, Donmanski MJ, Cohn JN. Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction. New Engl J Med 344:1351-1357, 2001
    • (2001) New Engl J Med , vol.344 , pp. 1351-1357
    • Exner, D.V.1    Dries, D.L.2    Donmanski, M.J.3    Cohn, J.N.4
  • 21
    • 0031028894 scopus 로고    scopus 로고
    • The angiotensinogen T235 variant and the use of antihypertensive drugs in a population-based cohort
    • Schunkert H, Hense HW, Gimenez-Roqueplo AP, et al. The angiotensinogen T235 variant and the use of antihypertensive drugs in a population-based cohort. Hypertension 29:628-633, 1997
    • (1997) Hypertension , vol.29 , pp. 628-633
    • Schunkert, H.1    Hense, H.W.2    Gimenez-Roqueplo, A.P.3
  • 22
    • 0029586504 scopus 로고
    • Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition
    • Hingorani AD, Jia H, Stevens PA, et al. Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition. J Hypertens 13:1602-1609, 1995
    • (1995) J Hypertens , vol.13 , pp. 1602-1609
    • Hingorani, A.D.1    Jia, H.2    Stevens, P.A.3
  • 23
    • 0033406766 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor gene polymorphism predicts response to losartan and angiotensin II
    • Miller JA, Thai K, Sholey JW. Angiotensin II type 1 receptor gene polymorphism predicts response to losartan and angiotensin II. Kidney Int 56:2173-2180, 1999
    • (1999) Kidney Int , vol.56 , pp. 2173-2180
    • Miller, J.A.1    Thai, K.2    Sholey, J.W.3
  • 24
    • 10544228945 scopus 로고    scopus 로고
    • Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of perindopril and nitrendipine on arterial stiffness in hypertensive individuals
    • Benetos A, Cambien F, Gautier S, et al. Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of perindopril and nitrendipine on arterial stiffness in hypertensive individuals. Hypertension 28:1081-1084, 1996
    • (1996) Hypertension , vol.28 , pp. 1081-1084
    • Benetos, A.1    Cambien, F.2    Gautier, S.3
  • 25
    • 0033858856 scopus 로고    scopus 로고
    • Bradykinin B2 receptor gene polymorphism is associated with angiotensin-converting enzyme inhibitor-related cough
    • Mukae S, Aoki S, Itoh S, et al. Bradykinin B2 receptor gene polymorphism is associated with angiotensin-converting enzyme inhibitor-related cough. Hypertension 36:127-131, 2000
    • (2000) Hypertension , vol.36 , pp. 127-131
    • Mukae, S.1    Aoki, S.2    Itoh, S.3
  • 26
    • 0034942087 scopus 로고    scopus 로고
    • The ACE gene polymorphism and cough threshold for capaicin after cilazapril usage
    • Takahashi T, Yamaguchi E, Furuya K, Kawakami Y. The ACE gene polymorphism and cough threshold for capaicin after cilazapril usage. Respir Med 95:130-135, 2001
    • (2001) Respir Med , vol.95 , pp. 130-135
    • Takahashi, T.1    Yamaguchi, E.2    Furuya, K.3    Kawakami, Y.4
  • 27
    • 0035957262 scopus 로고    scopus 로고
    • Pharmacogenetic interactions between beta-blocker therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure
    • McNamara DM, Holubkov R, Janosko K, et al. Pharmacogenetic interactions between beta-blocker therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure. Circulation 103:1644-1648, 2001
    • (2001) Circulation , vol.103 , pp. 1644-1648
    • McNamara, D.M.1    Holubkov, R.2    Janosko, K.3
  • 28
    • 0035957261 scopus 로고    scopus 로고
    • Preprescription genotyping: Not yet ready for prime time, but getting there
    • Roden DM, Brown NJ. Preprescription genotyping: Not yet ready for prime time, but getting there, Circulation 103:1608-1610, 2001
    • (2001) Circulation , vol.103 , pp. 1608-1610
    • Roden, D.M.1    Brown, N.J.2
  • 29
    • 0035046061 scopus 로고    scopus 로고
    • Beta-adrenergic receptors in the failing heart: The good, the bad, and the unknown
    • Liggett SB. Beta-adrenergic receptors in the failing heart: The good, the bad, and the unknown. J Clin Invest 107:947-948, 2001
    • (2001) J Clin Invest , vol.107 , pp. 947-948
    • Liggett, S.B.1
  • 30
    • 0035105777 scopus 로고    scopus 로고
    • Pharmacogenetic applications of the Human Genome Project
    • Liggett SB. Pharmacogenetic applications of the Human Genome Project. Nature Medicine 2001:281-283, 2001
    • (2001) Nature Medicine , vol.2001 , pp. 281-283
    • Liggett, S.B.1
  • 31
    • 0033617342 scopus 로고    scopus 로고
    • A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor
    • Mason DA, Moore JD, Green SA, Liggett SB. A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor. J Biol Chem 274:12670-12674, 1999
    • (1999) J Biol Chem , vol.274 , pp. 12670-12674
    • Mason, D.A.1    Moore, J.D.2    Green, S.A.3    Liggett, S.B.4
  • 32
    • 0034725616 scopus 로고    scopus 로고
    • A four amino acid deletion polymorphism in the third intracellular loop of the human alpha2C-adrenergic receptor confers impaired coupling to multiple effectors
    • Small KM, Forbes SL, Rahman FF, Bridges KM, Liggett SB. A four amino acid deletion polymorphism in the third intracellular loop of the human alpha2C-adrenergic receptor confers impaired coupling to multiple effectors. J Biol Chem 275:23059-23064, 2000
    • (2000) J Biol Chem , vol.275 , pp. 23059-23064
    • Small, K.M.1    Forbes, S.L.2    Rahman, F.F.3    Bridges, K.M.4    Liggett, S.B.5
  • 33
    • 0037057235 scopus 로고    scopus 로고
    • Synergistic polymorphisms of beta1- and alpha 2c-adrenergic receptors and the risk of congestive heart failure
    • Small KM, Wagoner LE, Levin AM, Kardia SLR, Liggett SB. Synergistic polymorphisms of beta1- and alpha 2c-adrenergic receptors and the risk of congestive heart failure. N Engl J Med 347:1135-1142, 2002
    • (2002) N Engl J Med , vol.347 , pp. 1135-1142
    • Small, K.M.1    Wagoner, L.E.2    Levin, A.M.3    Kardia, S.L.R.4    Liggett, S.B.5
  • 34
    • 0035497742 scopus 로고    scopus 로고
    • Effect of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia
    • Humma LM, Puckett BJ, Richardson HE, et al. Effect of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia. Am J Cardiol 88:1034-1037, 2001
    • (2001) Am J Cardiol , vol.88 , pp. 1034-1037
    • Humma, L.M.1    Puckett, B.J.2    Richardson, H.E.3
  • 35
    • 0033821403 scopus 로고    scopus 로고
    • The gain-of-function G389R variant of the beta1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects
    • S'Shaughnessy KM, Fu B, Dickerson C, Thurston D, Brown MJ. The gain-of-function G389R variant of the beta1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects. Clin Sci 99:233-238, 2000
    • (2000) Clin Sci , vol.99 , pp. 233-238
    • S'Shaughnessy, K.M.1    Fu, B.2    Dickerson, C.3    Thurston, D.4    Brown, M.J.5
  • 36
    • 0032495541 scopus 로고    scopus 로고
    • The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
    • Kuivenhoven JA, Jukerna JW, Zwinderman AH, et al. The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. N Engl J Med 338:86-93, 1998
    • (1998) N Engl J Med , vol.338 , pp. 86-93
    • Kuivenhoven, J.A.1    Jukerna, J.W.2    Zwinderman, A.H.3
  • 37
    • 0012605419 scopus 로고    scopus 로고
    • The cholesterol ester transfer protein Taq 1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease
    • in press
    • Carlquist JF, Muhlestein JB, Home BD, Hart NI, Bair TL, Molhuizen HOF, Anderson JL. The cholesterol ester transfer protein Taq 1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease. Am Heart J (in press), 2003
    • (2003) Am Heart J
    • Carlquist, J.F.1    Muhlestein, J.B.2    Home, B.D.3    Hart, N.I.4    Bair, T.L.5    Molhuizen, H.O.F.6    Anderson, J.L.7
  • 38
    • 0034724089 scopus 로고    scopus 로고
    • The apolipoprotein epsilon 4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction
    • Gerdes LU, Gerdes C, Dervinen K, et al. The apolipoprotein epsilon 4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction. Circulation 101:1366-1371, 2000
    • (2000) Circulation , vol.101 , pp. 1366-1371
    • Gerdes, L.U.1    Gerdes, C.2    Dervinen, K.3
  • 39
    • 0035852726 scopus 로고    scopus 로고
    • Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment
    • Zambon A, Deeb SS, Brown BG, Hokanson JE, Brunzell JD. Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment. Circulation 103:792-798, 2001
    • (2001) Circulation , vol.103 , pp. 792-798
    • Zambon, A.1    Deeb, S.S.2    Brown, B.G.3    Hokanson, J.E.4    Brunzell, J.D.5
  • 40
    • 0030587872 scopus 로고    scopus 로고
    • The Asp 9 Asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis
    • Jukema JW, van Boven AJ, Groenemeijer B, et al. The Asp9 Asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis. Circulation 94:1913-1918, 1996
    • (1996) Circulation , vol.94 , pp. 1913-1918
    • Jukema, J.W.1    Van Boven, A.J.2    Groenemeijer, B.3
  • 41
    • 0033957209 scopus 로고    scopus 로고
    • Interactions between angiotensin-I converting enzyme insertion/deletion polymorphism and response of plasma lipids and coronary atherosclerosis to treatment with fluvastatin: The lipoprotein and coronary atherosclerosis study
    • Marian AJ, Safavi F, Ferlic L, et al. Interactions between angiotensin-I converting enzyme insertion/deletion polymorphism and response of plasma lipids and coronary atherosclerosis to treatment with fluvastatin: The lipoprotein and coronary atherosclerosis study. J Am Coll Cardiol 35:89-95, 2000
    • (2000) J Am Coll Cardiol , vol.35 , pp. 89-95
    • Marian, A.J.1    Safavi, F.2    Ferlic, L.3
  • 42
    • 0032127219 scopus 로고    scopus 로고
    • The 5A/6A polymorphism in the promoter of the stromelysin-1 gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study
    • Humphries SE, Luong LA, Talmud PJ, et al. The 5A/6A polymorphism in the promoter of the stromelysin-1 gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study. Atherosclerosis 139:49-56, 1998
    • (1998) Atherosclerosis , vol.139 , pp. 49-56
    • Humphries, S.E.1    Luong, L.A.2    Talmud, P.J.3
  • 43
    • 0033002576 scopus 로고    scopus 로고
    • Effect of the stromelysin- 1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis
    • de Maat MP, Jukema JW, Ye S, et al. Effect of the stromelysin-1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis. Am J Cardiol 83:852-856, 1999
    • (1999) Am J Cardiol , vol.83 , pp. 852-856
    • De Maat, M.P.1    Jukema, J.W.2    Ye, S.3
  • 44
    • 0031836563 scopus 로고    scopus 로고
    • 455G/A polymorphism of the betafibrinogen gene is associated with the progression of coronary atherosclerosis in symptomatic men
    • de Maat MP, Kastelein JJ, Jukema JW, et al. -455G/A polymorphism of the betafibrinogen gene is associated with the progression of coronary atherosclerosis in symptomatic men. Arterioscler Thromb Vasc Biol 18:265-271, 1998
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 265-271
    • De Maat, M.P.1    Kastelein, J.J.2    Jukema, J.W.3
  • 45
    • 0035909968 scopus 로고    scopus 로고
    • Low hepatic lipase activity is a novel risk factor for coronary artery disease
    • Dugi KA, Brandauer K, Schmidt N, et al. Low hepatic lipase activity is a novel risk factor for coronary artery disease. Circulation 104:3057-3062, 2001
    • (2001) Circulation , vol.104 , pp. 3057-3062
    • Dugi, K.A.1    Brandauer, K.2    Schmidt, N.3
  • 46
    • 0346555315 scopus 로고    scopus 로고
    • The role of alpha-adducin polymorphism in blood pressure and sodium handling regulation may not be excluded by a negative association study
    • Glorioso N, Manunta P, Filigheddu F, et al. The role of alpha-adducin polymorphism in blood pressure and sodium handling regulation may not be excluded by a negative association study. Hypertension 37:739-743, 1999
    • (1999) Hypertension , vol.37 , pp. 739-743
    • Glorioso, N.1    Manunta, P.2    Filigheddu, F.3
  • 47
    • 0030898258 scopus 로고    scopus 로고
    • Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension
    • Cusi D, Barlassina C, Azzani T, et al. Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension. Lancet 349:1353-1357, 1997
    • (1997) Lancet , vol.349 , pp. 1353-1357
    • Cusi, D.1    Barlassina, C.2    Azzani, T.3
  • 48
    • 0035092564 scopus 로고    scopus 로고
    • C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic
    • Turner ST, Schwartz GL, Chapman AB, Boerwindle E. C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic. Hypertension 37:739-743, 2001
    • (2001) Hypertension , vol.37 , pp. 739-743
    • Turner, S.T.1    Schwartz, G.L.2    Chapman, A.B.3    Boerwindle, E.4
  • 49
    • 0032543748 scopus 로고    scopus 로고
    • High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives
    • Martinelli I, Sacchi E, Landi G, et al. High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives. N Engl J Med 338:1840-1841, 1998
    • (1998) N Engl J Med , vol.338 , pp. 1840-1841
    • Martinelli, I.1    Sacchi, E.2    Landi, G.3
  • 50
    • 0032976317 scopus 로고    scopus 로고
    • Interaction between the G 20210A mutation of the prothrombin gene and oral contraceptive use in deep vein thrombosis
    • Martinelli I, Taioli E, Bucciarelli P, Akhavan S, Mannucci PM. Interaction between the G20210A mutation of the prothrombin gene and oral contraceptive use in deep vein thrombosis. Arterioscler Thromb Vasc Biol 19:700-703, 1999
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 700-703
    • Martinelli, I.1    Taioli, E.2    Bucciarelli, P.3    Akhavan, S.4    Mannucci, P.M.5
  • 51
    • 18244414272 scopus 로고    scopus 로고
    • Platelet GP IIIa P1(A) polymorphisms display different sensitivities to agonists
    • Michelson AD, Furman MI, Goldschmidt-Clermont P, et al. Platelet GP IIIa P1(A) polymorphisms display different sensitivities to agonists. Circulation 101:1013-1018, 2000
    • (2000) Circulation , vol.101 , pp. 1013-1018
    • Michelson, A.D.1    Furman, M.I.2    Goldschmidt-Clermont, P.3
  • 52
    • 0032170569 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: New insights into the impact of the FcgammaRIIa-R-H 131 polymorphism
    • Carlsson LE, Santoso S, Baurichter G, et al. Heparin-induced thrombocytopenia: New insights into the impact of the FcgammaRIIa-R-H131 polymorphism. Blood 92:1526-1531, 1998
    • (1998) Blood , vol.92 , pp. 1526-1531
    • Carlsson, L.E.1    Santoso, S.2    Baurichter, G.3
  • 53
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch NJ. Searching for genetic determinants in the new millennium. Nature 405:847-856, 2000
    • (2000) Nature , vol.405 , pp. 847-856
    • Risch, N.J.1
  • 54
    • 0036065699 scopus 로고    scopus 로고
    • SNP judgments and freedom of association
    • Hegele RA. SNP judgments and freedom of association. Arterioscler Thromb Vasc Biol 22:1058-1061, 2002
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1058-1061
    • Hegele, R.A.1
  • 56
    • 0036071296 scopus 로고    scopus 로고
    • Testing for population subdivision and association in four case-control studies
    • Ardlie KG, Lunmetta KL, Seielstad M. Testing for population subdivision and association in four case-control studies. Am J Hum Genet 71:304-311, 2002
    • (2002) Am J Hum Genet , vol.71 , pp. 304-311
    • Ardlie, K.G.1    Lunmetta, K.L.2    Seielstad, M.3
  • 57
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel SB, Schaffner SF, Nguyen H, et al. The structure of haplotype blocks in the human genome. Science 296:2225-2229, 2002
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 58
    • 18444396271 scopus 로고    scopus 로고
    • A first-generation linkage disequilibrium map of human chromosome 22
    • Dawson E, Abecasis GR, Bumpstead S, et al. A first-generation linkage disequilibrium map of human chromosome 22. Nature 418:544-548, 2002
    • (2002) Nature , vol.418 , pp. 544-548
    • Dawson, E.1    Abecasis, G.R.2    Bumpstead, S.3
  • 59
    • 0035941029 scopus 로고    scopus 로고
    • Blocks of limited haplotype diversity revealed by high resolution scanning of human chromosome 21
    • Patil N, Berno AJ, Hinds DA, et al. Blocks of limited haplotype diversity revealed by high resolution scanning of human chromosome 21. Science 294:1719-1723, 2001
    • (2001) Science , vol.294 , pp. 1719-1723
    • Patil, N.1    Berno, A.J.2    Hinds, D.A.3
  • 60
    • 0035861049 scopus 로고    scopus 로고
    • Potential role of pharmacogenomics in reducing adverse drug reactions
    • Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. Potential role of pharmacogenomics in reducing adverse drug reactions. JAMA 286:2270-2279, 2001
    • (2001) JAMA , vol.286 , pp. 2270-2279
    • Phillips, K.A.1    Veenstra, D.L.2    Oren, E.3    Lee, J.K.4    Sadee, W.5
  • 61
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • Lazarou J, Pomeranz B, Corey P. Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies. JAMA 279:1200-1205, 1998
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.2    Corey, P.3
  • 63
    • 0033608466 scopus 로고    scopus 로고
    • Association of polymorphisms in the cytochrome P 450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
    • Aithal GP, Day CP, Kesteven PJ, et al. Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 353:717-719, 1999
    • (1999) Lancet , vol.353 , pp. 717-719
    • Aithal, G.P.1    Day, C.P.2    Kesteven, P.J.3
  • 64
    • 0037012465 scopus 로고    scopus 로고
    • Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
    • Higashi MK, Veenstra DL, Kondo LM, et al. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 287:1690-1698, 2002
    • (2002) JAMA , vol.287 , pp. 1690-1698
    • Higashi, M.K.1    Veenstra, D.L.2    Kondo, L.M.3
  • 65
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk L, von Richter O, et al. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 97:3473-3478, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, L.2    Von Richter, O.3
  • 67
    • 0034641652 scopus 로고    scopus 로고
    • Plasma homocysteine predicts mortality independently of traditional risk factors and C-reactive protein in patients with angiographically defined coronary artery disease
    • Anderson JL, Muhlestein JB, Home BD, et al. Plasma homocysteine predicts mortality independently of traditional risk factors and C-reactive protein in patients with angiographically defined coronary artery disease. Circulation 102:1227-1232, 2000
    • (2000) Circulation , vol.102 , pp. 1227-1232
    • Anderson, J.L.1    Muhlestein, J.B.2    Home, B.D.3
  • 68
    • 85038469939 scopus 로고    scopus 로고
    • Polymorphisms of the CETP, ABC, MTHFR, LPL, and PAI-1 genes predict intermediate endpoints but not angiographic coronary artery disease
    • abstract (in press)
    • Horne BD, Anderson JL, Muhlestein JB, et al. Polymorphisms of the CETP, ABC, MTHFR, LPL, and PAI-1 genes predict intermediate endpoints but not angiographic coronary artery disease. J Am Coll Cardiol 41:abstract (in press), 2003
    • (2003) J Am Coll Cardiol , vol.41
    • Horne, B.D.1    Anderson, J.L.2    Muhlestein, J.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.